Increased mTORC1 Signaling UPRegulates Stress

Molecular Cell

Volumn 29, Issue 5, 2008, Pages 533-535

  Reiling, Jan H ^a,b   Sabatini, David M ^a,b,c  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; BORTEZOMIB; CANNABINOID; CISPLATIN; CYCLOHEXIMIDE; EDELFOSINE; GELDANAMYCIN; INSULIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; S6 KINASE;

CANCER CELL; CONFORMATION; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; HUMAN; NONHUMAN; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN SYNTHESIS; SHORT SURVEY; UPREGULATION;

ANIMALS; ENDOPLASMIC RETICULUM; HUMANS; MICE; NEOPLASMS; OXIDATIVE STRESS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 40649120732     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2008.02.011     Document Type: Short Survey

References (11)

1. Endo H., Murata K., Mukai M., Ishikawa O., and Inoue M. Cancer Res. 67 (2007) 8095-8103
2. Guertin D.A., and Sabatini D.M. Cancer Cell 12 (2007) 9-22
3. Inoki K., Zhu T., and Guan K.L. Cell 115 (2003) 577-590
4. Kaper F., Dornhoefer N., and Giaccia A.J. Cancer Res. 66 (2006) 1561-1569
5. Lee A.H., Iwakoshi N.N., Anderson K.C., and Glimcher L.H. Proc. Natl. Acad. Sci. USA 100 (2003) 9946-9951
6. Ma Y., and Hendershot L.M. Nat. Rev. Cancer 4 (2004) 966-977
7. Moenner M., Pluquet O., Bouchecareilh M., and Chevet E. Cancer Res. 67 (2007) 10631-10634
8. Nawrocki S.T., Carew J.S., Pino M.S., Highway R.A., Dunner Jr. K., Huang P., Abbruzzese J.L., and McConkey D.J. Cancer Res. 65 (2005) 11658-11666
9. Nieto-Miguel T., Fonteriz R.I., Vay L., Gajate C., Lopez-Hernandez S., and Mollinedo F. Cancer Res. 67 (2007) 10368-10378
10. Ozcan U., Cao Q., Yilmaz E., Lee A.H., Iwakoshi N.N., Ozdelen E., Tuncman G., Gorgun C., Glimcher L.H., and Hotamisligil G.S. Science 306 (2004) 457-461
11. Ozcan U., Ozcan L., Yilmaz E., Düvel K., Sahin M., Manning B.D., and Hotamisligil G.S. Mol. Cell 29 (2008) 541-551 this issue