-
1
-
-
10744233783
-
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
-
Backman S.A., Ghazarian D., So K., Sanchez O., Wagner K.U., Hennighausen L., Suzuki A., Tsao M.S., Chapman W.B., Stambolic V., Mak T.W. Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten. Proc. Natl. Acad. Sci. U. S. A. 2004, 6:1725-1730.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.6
, pp. 1725-1730
-
-
Backman, S.A.1
Ghazarian, D.2
So, K.3
Sanchez, O.4
Wagner, K.U.5
Hennighausen, L.6
Suzuki, A.7
Tsao, M.S.8
Chapman, W.B.9
Stambolic, V.10
Mak, T.W.11
-
2
-
-
0037444638
-
A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse
-
Badea T.C., Wang Y., Nathans J. A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse. J. Neurosci. 2003, 6:2314-2322.
-
(2003)
J. Neurosci.
, vol.6
, pp. 2314-2322
-
-
Badea, T.C.1
Wang, Y.2
Nathans, J.3
-
3
-
-
34548241309
-
Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-Yl)pyrimido[2,1-alpha]isoquinolin-4-one
-
Ballou L.M., Selinger E.S., Choi J.Y., Drueckhammer D.G., Lin R.Z. Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-Yl)pyrimido[2,1-alpha]isoquinolin-4-one. J. Biol. Chem. 2007, 33:24463-24470.
-
(2007)
J. Biol. Chem.
, vol.33
, pp. 24463-24470
-
-
Ballou, L.M.1
Selinger, E.S.2
Choi, J.Y.3
Drueckhammer, D.G.4
Lin, R.Z.5
-
4
-
-
2442528552
-
Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells
-
Baron S., Manin M., Beaudoin C., Leotoing L., Communal Y., Veyssiere G., Morel L. Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells. J. Biol. Chem. 2004, 15:14579-14586.
-
(2004)
J. Biol. Chem.
, vol.15
, pp. 14579-14586
-
-
Baron, S.1
Manin, M.2
Beaudoin, C.3
Leotoing, L.4
Communal, Y.5
Veyssiere, G.6
Morel, L.7
-
5
-
-
34047095297
-
The two TORCs and Akt
-
Bhaskar P.T., Hay N. The two TORCs and Akt. Dev. Cell 2007, 4:487-502.
-
(2007)
Dev. Cell
, vol.4
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
6
-
-
0033561173
-
Roles for Nkx3.1 in prostate development and cancer
-
Bhatia-Gaur R., Donjacour A.A., Sciavolino P.J., Kim M., Desai N., Young P., Norton C.R., Gridley T., Cardiff R.D., Cunha G.R., Abate-Shen C., Shen M.M. Roles for Nkx3.1 in prostate development and cancer. Genes Dev. 1999, 8:966-977.
-
(1999)
Genes Dev.
, vol.8
, pp. 966-977
-
-
Bhatia-Gaur, R.1
Donjacour, A.A.2
Sciavolino, P.J.3
Kim, M.4
Desai, N.5
Young, P.6
Norton, C.R.7
Gridley, T.8
Cardiff, R.D.9
Cunha, G.R.10
Abate-Shen, C.11
Shen, M.M.12
-
7
-
-
0033574429
-
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase
-
Bi L., Okabe I., Bernard D.J., Wynshaw-Boris A., Nussbaum R.L. Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J. Biol. Chem. 1999, 16:10963-10968.
-
(1999)
J. Biol. Chem.
, vol.16
, pp. 10963-10968
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Wynshaw-Boris, A.4
Nussbaum, R.L.5
-
8
-
-
0036185944
-
Early embryonic lethality in mice deficient in the p110beta catalytic subunit of Pi 3-kinase
-
Bi L., Okabe I., Bernard D.J., Nussbaum R.L. Early embryonic lethality in mice deficient in the p110beta catalytic subunit of Pi 3-kinase. Mamm. Genome 2002, 3:169-172.
-
(2002)
Mamm. Genome
, vol.3
, pp. 169-172
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Nussbaum, R.L.4
-
9
-
-
0029768633
-
Prostate-specific and androgen-dependent expression of a novel homeobox gene
-
Bieberich C.J., Fujita K., He W.W., Jay G. Prostate-specific and androgen-dependent expression of a novel homeobox gene. J. Biol. Chem. 1996, 50:31779-31782.
-
(1996)
J. Biol. Chem.
, vol.50
, pp. 31779-31782
-
-
Bieberich, C.J.1
Fujita, K.2
He, W.W.3
Jay, G.4
-
10
-
-
14144250240
-
Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice
-
Brachmann S.M., Ueki K., Engelman J.A., Kahn R.C., Cantley L.C. Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice. Mol. Cell. Biol. 2005, 5:1596-1607.
-
(2005)
Mol. Cell. Biol.
, vol.5
, pp. 1596-1607
-
-
Brachmann, S.M.1
Ueki, K.2
Engelman, J.A.3
Kahn, R.C.4
Cantley, L.C.5
-
11
-
-
0029831167
-
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
-
Brunn G.J., Williams J., Sabers C., Wiederrecht G., Lawrence J.C., Abraham R.T. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J. 1996, 19:5256-5267.
-
(1996)
EMBO J.
, vol.19
, pp. 5256-5267
-
-
Brunn, G.J.1
Williams, J.2
Sabers, C.3
Wiederrecht, G.4
Lawrence, J.C.5
Abraham, R.T.6
-
12
-
-
77954985337
-
Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis
-
Cai H., Das S., Kamimura Y., Long Y., Parent C.A., Devreotes P.N. Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis. J. Cell Biol. 2010, 2:233-245.
-
(2010)
J. Cell Biol.
, vol.2
, pp. 233-245
-
-
Cai, H.1
Das, S.2
Kamimura, Y.3
Long, Y.4
Parent, C.A.5
Devreotes, P.N.6
-
13
-
-
69249206717
-
MTOR mediates Wnt-induced epidermal stem cell exhaustion and aging
-
Castilho R.M., Squarize C.H., Chodosh L.A., Williams B.O., Gutkind J.S. MTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. Cell Stem Cell 2009, 5:279-289.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 279-289
-
-
Castilho, R.M.1
Squarize, C.H.2
Chodosh, L.A.3
Williams, B.O.4
Gutkind, J.S.5
-
14
-
-
77952920346
-
A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration
-
Charest P.G., Shen Z., Lakoduk A., Sasaki A.T., Briggs S.P., Firtel R.A. A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration. Dev. Cell 2010, 5:737-749.
-
(2010)
Dev. Cell
, vol.5
, pp. 737-749
-
-
Charest, P.G.1
Shen, Z.2
Lakoduk, A.3
Sasaki, A.T.4
Briggs, S.P.5
Firtel, R.A.6
-
15
-
-
28444464758
-
Distinct regulatory elements mediate the dynamic expression pattern of Nkx3.1
-
Chen H., Mutton L.N., Prins G.S., Bieberich C.J. Distinct regulatory elements mediate the dynamic expression pattern of Nkx3.1. Dev. Dyn. 2005, 4:961-973.
-
(2005)
Dev. Dyn.
, vol.4
, pp. 961-973
-
-
Chen, H.1
Mutton, L.N.2
Prins, G.S.3
Bieberich, C.J.4
-
16
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen C., Liu Y., Liu R., Ikenoue T., Guan K.L., Liu Y., Zheng P. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Med. 2008, 205:2397-2408.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Liu, Y.6
Zheng, P.7
-
17
-
-
0015535245
-
The role of androgens in the epithelio-mesenchymal interactions involved in prostatic morphogenesis in embryonic mice
-
Cunha G.R. The role of androgens in the epithelio-mesenchymal interactions involved in prostatic morphogenesis in embryonic mice. Anat. Rec. 1973, 1:87-96.
-
(1973)
Anat. Rec.
, vol.1
, pp. 87-96
-
-
Cunha, G.R.1
-
18
-
-
0018002388
-
The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice
-
Cunha G.R., Lung B. The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice. J. Exp. Zool. 1978, 2:181-193.
-
(1978)
J. Exp. Zool.
, vol.2
, pp. 181-193
-
-
Cunha, G.R.1
Lung, B.2
-
19
-
-
79952985551
-
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
-
Delgoffe G.M., Pollizzi K.N., Waickman A.T., Heikamp E., Meyers D.J., Horton M.R., Xiao B., Worley P.F., Powell J.D. The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat. Immunol. 2011, 4:295-303.
-
(2011)
Nat. Immunol.
, vol.4
, pp. 295-303
-
-
Delgoffe, G.M.1
Pollizzi, K.N.2
Waickman, A.T.3
Heikamp, E.4
Meyers, D.J.5
Horton, M.R.6
Xiao, B.7
Worley, P.F.8
Powell, J.D.9
-
20
-
-
28744444214
-
Growth, morphogenesis, and differentiation during mouse prostate development in situ, in renal grafts, and in vitro
-
Doles J.D., Vezina C.M., Lipinski R.J., Peterson R.E., Bushman W. Growth, morphogenesis, and differentiation during mouse prostate development in situ, in renal grafts, and in vitro. Prostate 2005, 4:390-399.
-
(2005)
Prostate
, vol.4
, pp. 390-399
-
-
Doles, J.D.1
Vezina, C.M.2
Lipinski, R.J.3
Peterson, R.E.4
Bushman, W.5
-
21
-
-
0042162919
-
FGF-10 plays an essential role in the growth of the fetal prostate
-
Donjacour A.A., Thomson A.A., Cunha G.R. FGF-10 plays an essential role in the growth of the fetal prostate. Dev. Biol. 2003, 1:39-54.
-
(2003)
Dev. Biol.
, vol.1
, pp. 39-54
-
-
Donjacour, A.A.1
Thomson, A.A.2
Cunha, G.R.3
-
22
-
-
33845896298
-
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis
-
Ferguson G.J., Milne L., Kulkarni S., Sasaki T., Walker S., Andrews S., Crabbe T., Finan P., Jones G., Jackson S., Camps M., Rommel C., Wymann M., Hirsch E., Hawkins P., Stephens L. PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat. Cell Biol. 2007, 1:86-91.
-
(2007)
Nat. Cell Biol.
, vol.1
, pp. 86-91
-
-
Ferguson, G.J.1
Milne, L.2
Kulkarni, S.3
Sasaki, T.4
Walker, S.5
Andrews, S.6
Crabbe, T.7
Finan, P.8
Jones, G.9
Jackson, S.10
Camps, M.11
Rommel, C.12
Wymann, M.13
Hirsch, E.14
Hawkins, P.15
Stephens, L.16
-
23
-
-
58149108929
-
Cell migration and activated PI3K/AKT-directed elongation in the developing rat Mullerian duct
-
Fujino A., Arango N.A., Zhan Y., Manganaro T.F., Li X., MacLaughlin D.T., Donahoe P.K. Cell migration and activated PI3K/AKT-directed elongation in the developing rat Mullerian duct. Dev. Biol. 2009, 2:351-362.
-
(2009)
Dev. Biol.
, vol.2
, pp. 351-362
-
-
Fujino, A.1
Arango, N.A.2
Zhan, Y.3
Manganaro, T.F.4
Li, X.5
MacLaughlin, D.T.6
Donahoe, P.K.7
-
24
-
-
58049196780
-
MTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization
-
Gan B., Sahin E., Jiang S., Sanchez-Aguilera A., Scott K.L., Chin L., Williams D.A., Kwiatkowski D.J., DePinho R.A. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:19384-19389.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 19384-19389
-
-
Gan, B.1
Sahin, E.2
Jiang, S.3
Sanchez-Aguilera, A.4
Scott, K.L.5
Chin, L.6
Williams, D.A.7
Kwiatkowski, D.J.8
DePinho, R.A.9
-
25
-
-
19944432425
-
Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro
-
Griffin R.J., Fontana G., Golding B.T., Guiard S., Hardcastle I.R., Leahy J.J., Martin N., Richardson C., Rigoreau L., Stockley M., Smith G.C. Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro. J. Med. Chem. 2005, 2:569-585.
-
(2005)
J. Med. Chem.
, vol.2
, pp. 569-585
-
-
Griffin, R.J.1
Fontana, G.2
Golding, B.T.3
Guiard, S.4
Hardcastle, I.R.5
Leahy, J.J.6
Martin, N.7
Richardson, C.8
Rigoreau, L.9
Stockley, M.10
Smith, G.C.11
-
26
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin D.A., Sabatini D.M. Defining the role of mTOR in cancer. Cancer Cell 2007, 1:9-22.
-
(2007)
Cancer Cell
, vol.1
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
27
-
-
68149096799
-
The pharmacology of mTOR inhibition
-
pe24
-
Guertin D.A., Sabatini D.M. The pharmacology of mTOR inhibition. Sci. Signal. 2009, 67. pe24.
-
(2009)
Sci. Signal.
, vol.67
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
28
-
-
33751348056
-
Ablation in mice of the mTORC components Raptor, Rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
-
Guertin D.A., Stevens D.M., Thoreen C.C., Burds A.A., Kalaany N.Y., Moffat J., Brown M., Fitzgerald K.J., Sabatini D.M. Ablation in mice of the mTORC components Raptor, Rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev. Cell 2006, 6:859-871.
-
(2006)
Dev. Cell
, vol.6
, pp. 859-871
-
-
Guertin, D.A.1
Stevens, D.M.2
Thoreen, C.C.3
Burds, A.A.4
Kalaany, N.Y.5
Moffat, J.6
Brown, M.7
Fitzgerald, K.J.8
Sabatini, D.M.9
-
29
-
-
58649114084
-
MTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice
-
Guertin D.A., Stevens D.M., Saitoh M., Kinkel S., Crosby K., Sheen J.H., Mullholland D.J., Magnuson M.A., Wu H., Sabatini D.M. MTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell 2009, 2:148-159.
-
(2009)
Cancer Cell
, vol.2
, pp. 148-159
-
-
Guertin, D.A.1
Stevens, D.M.2
Saitoh, M.3
Kinkel, S.4
Crosby, K.5
Sheen, J.H.6
Mullholland, D.J.7
Magnuson, M.A.8
Wu, H.9
Sabatini, D.M.10
-
30
-
-
0025100521
-
Primary culture of normal rat mammary epithelial cells within a basement membrane matrix. II. Functional differentiation under serum-free conditions
-
Hahm H.A., Ip M.M., Darcy K., Black J.D., Shea W.K., Forczek S., Yoshimura M., Oka T. Primary culture of normal rat mammary epithelial cells within a basement membrane matrix. II. Functional differentiation under serum-free conditions. In Vitro Cell. Dev. Biol. 1990, 8:803-814.
-
(1990)
In Vitro Cell. Dev. Biol.
, vol.8
, pp. 803-814
-
-
Hahm, H.A.1
Ip, M.M.2
Darcy, K.3
Black, J.D.4
Shea, W.K.5
Forczek, S.6
Yoshimura, M.7
Oka, T.8
-
31
-
-
12944299782
-
The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens
-
Huang L., Pu Y., Alam S., Birch L., Prins G.S. The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens. Dev. Biol. 2005, 2:396-414.
-
(2005)
Dev. Biol.
, vol.2
, pp. 396-414
-
-
Huang, L.1
Pu, Y.2
Alam, S.3
Birch, L.4
Prins, G.S.5
-
32
-
-
45849107594
-
The mTOR signaling network: insights from its role during embryonic development
-
Hwang M., Perez C.A., Moretti L., Lu B. The mTOR signaling network: insights from its role during embryonic development. Curr. Med. Chem. 2008, 15:1192-1208.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 1192-1208
-
-
Hwang, M.1
Perez, C.A.2
Moretti, L.3
Lu, B.4
-
33
-
-
0037205230
-
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
-
Iijima M., Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 2002, 5:599-610.
-
(2002)
Cell
, vol.5
, pp. 599-610
-
-
Iijima, M.1
Devreotes, P.2
-
34
-
-
0036773899
-
Temporal and spatial regulation of chemotaxis
-
Iijima M., Huang Y.E., Devreotes P. Temporal and spatial regulation of chemotaxis. Dev. Cell 2002, 4:469-478.
-
(2002)
Dev. Cell
, vol.4
, pp. 469-478
-
-
Iijima, M.1
Huang, Y.E.2
Devreotes, P.3
-
35
-
-
33646383684
-
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling
-
Knight Z.A., Gonzalez B., Feldman M.E., Zunder E.R., Goldenberg D.D., Williams O., Loewith R., Stokoe D., Balla A., Toth B., Balla T., Weiss W.A., Williams R.L., Shokat K.M. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell 2006, 4:733-747.
-
(2006)
Cell
, vol.4
, pp. 733-747
-
-
Knight, Z.A.1
Gonzalez, B.2
Feldman, M.E.3
Zunder, E.R.4
Goldenberg, D.D.5
Williams, O.6
Loewith, R.7
Stokoe, D.8
Balla, A.9
Toth, B.10
Balla, T.11
Weiss, W.A.12
Williams, R.L.13
Shokat, K.M.14
-
36
-
-
42149177825
-
The regulation of cell motility and chemotaxis by phospholipid signaling
-
Kolsch V., Charest P.G., Firtel R.A. The regulation of cell motility and chemotaxis by phospholipid signaling. J. Cell. Sci. 2008, Pt 5:551-559.
-
(2008)
J. Cell. Sci.
, Issue.PART 5
, pp. 551-559
-
-
Kolsch, V.1
Charest, P.G.2
Firtel, R.A.3
-
37
-
-
34548133730
-
Fibroblast growth factor receptor signaling through MEK-ERK is required for prostate bud induction
-
Kuslak S.L., Marker P.C. Fibroblast growth factor receptor signaling through MEK-ERK is required for prostate bud induction. Differentiation 2007, 7:638-651.
-
(2007)
Differentiation
, vol.7
, pp. 638-651
-
-
Kuslak, S.L.1
Marker, P.C.2
-
38
-
-
0037333510
-
Role of PI 3-kinase and PIP3 in submandibular gland branching morphogenesis
-
Larsen M., Hoffman M.P., Sakai T., Neibaur J.C., Mitchell J.M., Yamada K.M. Role of PI 3-kinase and PIP3 in submandibular gland branching morphogenesis. Dev. Biol. 2003, 1:178-191.
-
(2003)
Dev. Biol.
, vol.1
, pp. 178-191
-
-
Larsen, M.1
Hoffman, M.P.2
Sakai, T.3
Neibaur, J.C.4
Mitchell, J.M.5
Yamada, K.M.6
-
39
-
-
0036195102
-
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene
-
Lesche R., Groszer M., Gao J., Wang Y., Messing A., Sun H., Liu X., Wu H. Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 2002, 2:148-149.
-
(2002)
Genesis
, vol.2
, pp. 148-149
-
-
Lesche, R.1
Groszer, M.2
Gao, J.3
Wang, Y.4
Messing, A.5
Sun, H.6
Liu, X.7
Wu, H.8
-
40
-
-
33947324354
-
Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis
-
Lin Y., Liu G., Zhang Y., Hu Y.P., Yu K., Lin C., McKeehan K., Xuan J.W., Ornitz D.M., Shen M.M., Greenberg N., McKeehan W.L., Wang F. Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis. Development 2007, 4:723-734.
-
(2007)
Development
, vol.4
, pp. 723-734
-
-
Lin, Y.1
Liu, G.2
Zhang, Y.3
Hu, Y.P.4
Yu, K.5
Lin, C.6
McKeehan, K.7
Xuan, J.W.8
Ornitz, D.M.9
Shen, M.M.10
Greenberg, N.11
McKeehan, W.L.12
Wang, F.13
-
41
-
-
0030906678
-
Differentiation of rat neonatal ventral prostates grown in a serum-free organ culture system
-
Lipschutz J.H., Foster B.A., Cunha G.R. Differentiation of rat neonatal ventral prostates grown in a serum-free organ culture system. Prostate 1997, 1:35-42.
-
(1997)
Prostate
, vol.1
, pp. 35-42
-
-
Lipschutz, J.H.1
Foster, B.A.2
Cunha, G.R.3
-
42
-
-
78649956469
-
MTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion
-
Liu L., Das S., Losert W., Parent C.A. MTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion. Dev. Cell 2010, 6:845-857.
-
(2010)
Dev. Cell
, vol.6
, pp. 845-857
-
-
Liu, L.1
Das, S.2
Losert, W.3
Parent, C.A.4
-
43
-
-
0002708968
-
Fibroblast growth factor-10. A second candidate stromal to epithelial cell andromedin in prostate
-
Lu W., Luo Y., Kan M., McKeehan W.L. Fibroblast growth factor-10. A second candidate stromal to epithelial cell andromedin in prostate. J. Biol. Chem. 1999, 18:12827-12834.
-
(1999)
J. Biol. Chem.
, vol.18
, pp. 12827-12834
-
-
Lu, W.1
Luo, Y.2
Kan, M.3
McKeehan, W.L.4
-
44
-
-
8444224619
-
Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis
-
Manning B.D. Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis. J. Cell Biol. 2004, 3:399-403.
-
(2004)
J. Cell Biol.
, vol.3
, pp. 399-403
-
-
Manning, B.D.1
-
45
-
-
23744516268
-
Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2
-
Manning B.D., Logsdon M.N., Lipovsky A.I., Abbott D., Kwiatkowski D.J., Cantley L.C. Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2. Genes Dev. 2005, 15:1773-1778.
-
(2005)
Genes Dev.
, vol.15
, pp. 1773-1778
-
-
Manning, B.D.1
Logsdon, M.N.2
Lipovsky, A.I.3
Abbott, D.4
Kwiatkowski, D.J.5
Cantley, L.C.6
-
46
-
-
0020579117
-
A morphometric analysis of rat ventral prostate in organ culture
-
Martikainen P., Suominen J. A morphometric analysis of rat ventral prostate in organ culture. Anat. Rec. 1983, 2:279-288.
-
(1983)
Anat. Rec.
, vol.2
, pp. 279-288
-
-
Martikainen, P.1
Suominen, J.2
-
47
-
-
35548932872
-
A global double-fluorescent Cre reporter mouse
-
Muzumdar M.D., Tasic B., Miyamichi K., Li L., Luo L. A global double-fluorescent Cre reporter mouse. Genesis 2007, 9:593-605.
-
(2007)
Genesis
, vol.9
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, L.4
Luo, L.5
-
48
-
-
0028943805
-
Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture
-
Nogawa H., Ito T. Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture. Development 1995, 4:1015-1022.
-
(1995)
Development
, vol.4
, pp. 1015-1022
-
-
Nogawa, H.1
Ito, T.2
-
49
-
-
0025861394
-
Substitution for mesenchyme by basement-membrane-like substratum and epidermal growth factor in inducing branching morphogenesis of mouse salivary epithelium
-
Nogawa H., Takahashi Y. Substitution for mesenchyme by basement-membrane-like substratum and epidermal growth factor in inducing branching morphogenesis of mouse salivary epithelium. Development 1991, 3:855-861.
-
(1991)
Development
, vol.3
, pp. 855-861
-
-
Nogawa, H.1
Takahashi, Y.2
-
50
-
-
32944457518
-
MTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
O'Reilly K.E., Rojo F., She Q.B., Solit D., Mills G.B., Smith D., Lane H., Hofmann F., Hicklin D.J., Ludwig D.L., Baselga J., Rosen N. MTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res. 2006, 3:1500-1508.
-
(2006)
Cancer Res.
, vol.3
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
Lane, H.7
Hofmann, F.8
Hicklin, D.J.9
Ludwig, D.L.10
Baselga, J.11
Rosen, N.12
-
51
-
-
47749093561
-
Molecular signaling pathways that regulate prostate gland development
-
Prins G.S., Putz O. Molecular signaling pathways that regulate prostate gland development. Differentiation 2008, 6:641-659.
-
(2008)
Differentiation
, vol.6
, pp. 641-659
-
-
Prins, G.S.1
Putz, O.2
-
52
-
-
47749085539
-
Gene expression profiling in the developing prostate
-
Pritchard C.C., Nelson P.S. Gene expression profiling in the developing prostate. Differentiation 2008, 6:624-640.
-
(2008)
Differentiation
, vol.6
, pp. 624-640
-
-
Pritchard, C.C.1
Nelson, P.S.2
-
53
-
-
62449179630
-
Conserved gene expression programs integrate mammalian prostate development and tumorigenesis
-
Pritchard C., Mecham B., Dumpit R., Coleman I., Bhattacharjee M., Chen Q., Sikes R.A., Nelson P.S. Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009, 5:1739-1747.
-
(2009)
Cancer Res.
, vol.5
, pp. 1739-1747
-
-
Pritchard, C.1
Mecham, B.2
Dumpit, R.3
Coleman, I.4
Bhattacharjee, M.5
Chen, Q.6
Sikes, R.A.7
Nelson, P.S.8
-
54
-
-
40649121309
-
Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma
-
Ratnacaram C.K., Teletin M., Jiang M., Meng X., Chambon P., Metzger D. Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma. Proc. Natl. Acad. Sci. U. S. A. 2008, 7:2521-2526.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.7
, pp. 2521-2526
-
-
Ratnacaram, C.K.1
Teletin, M.2
Jiang, M.3
Meng, X.4
Chambon, P.5
Metzger, D.6
-
55
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov D.D., Ali S.M., Sengupta S., Sheen J.H., Hsu P.P., Bagley A.F., Markhard A.L., Sabatini D.M. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol. Cell 2006, 2:159-168.
-
(2006)
Mol. Cell
, vol.2
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
56
-
-
34247177148
-
Non-invasive visualization of the lipid product of class I PI3K in transgenic mouse models
-
Sasaki T., Sasaki J., Watanabe K., Suzuki A. Non-invasive visualization of the lipid product of class I PI3K in transgenic mouse models. Biochem. Soc. Trans. 2007, Pt 2:215-218.
-
(2007)
Biochem. Soc. Trans.
, Issue.PART 2
, pp. 215-218
-
-
Sasaki, T.1
Sasaki, J.2
Watanabe, K.3
Suzuki, A.4
-
57
-
-
57349137675
-
Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
-
Schaeffer E.M., Marchionni L., Huang Z., Simons B., Blackman A., Yu W., Parmigiani G., Berman D.M. Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer. Oncogene 2008, 57:7180-7191.
-
(2008)
Oncogene
, vol.57
, pp. 7180-7191
-
-
Schaeffer, E.M.1
Marchionni, L.2
Huang, Z.3
Simons, B.4
Blackman, A.5
Yu, W.6
Parmigiani, G.7
Berman, D.M.8
-
58
-
-
2442601508
-
Bisperoxovanadium compounds are potent PTEN inhibitors
-
Schmid A.C., Byrne R.D., Vilar R., Woscholski R. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004, 1:35-38.
-
(2004)
FEBS Lett.
, vol.1
, pp. 35-38
-
-
Schmid, A.C.1
Byrne, R.D.2
Vilar, R.3
Woscholski, R.4
-
59
-
-
77957370442
-
Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock
-
Scott C.L., Walker D.J., Cwiklinski E., Tait C., Tee A.R., Land S.C. Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock. Am. J. Physiol. Lung Cell. Mol. Physiol. 2010, 4:L455-L471.
-
(2010)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.4
-
-
Scott, C.L.1
Walker, D.J.2
Cwiklinski, E.3
Tait, C.4
Tee, A.R.5
Land, S.C.6
-
60
-
-
33748950810
-
Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability
-
Shiota C., Woo J.T., Lindner J., Shelton K.D., Magnuson M.A. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev. Cell 2006, 4:583-589.
-
(2006)
Dev. Cell
, vol.4
, pp. 583-589
-
-
Shiota, C.1
Woo, J.T.2
Lindner, J.3
Shelton, K.D.4
Magnuson, M.A.5
-
61
-
-
42349113247
-
A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis
-
Shor B., Zhang W.G., Toral-Barza L., Lucas J., Abraham R.T., Gibbons J.J., Yu K. A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis. Cancer Res. 2008, 8:2934-2943.
-
(2008)
Cancer Res.
, vol.8
, pp. 2934-2943
-
-
Shor, B.1
Zhang, W.G.2
Toral-Barza, L.3
Lucas, J.4
Abraham, R.T.5
Gibbons, J.J.6
Yu, K.7
-
62
-
-
0005307025
-
Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate
-
Sugimura Y., Foster B.A., Hom Y.K., Lipschutz J.H., Rubin J.S., Finch P.W., Aaronson S.A., Hayashi N., Kawamura J., Cunha G.R. Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate. Int. J. Dev. Biol. 1996, 5:941-951.
-
(1996)
Int. J. Dev. Biol.
, vol.5
, pp. 941-951
-
-
Sugimura, Y.1
Foster, B.A.2
Hom, Y.K.3
Lipschutz, J.H.4
Rubin, J.S.5
Finch, P.W.6
Aaronson, S.A.7
Hayashi, N.8
Kawamura, J.9
Cunha, G.R.10
-
63
-
-
77955762208
-
TSC1/2 tumor suppressor complex maintains Drosophila germline stem cells by preventing differentiation
-
Sun P., Quan Z., Zhang B., Wu T., Xi R. TSC1/2 tumor suppressor complex maintains Drosophila germline stem cells by preventing differentiation. Development 2010, 137:2461-2469.
-
(2010)
Development
, vol.137
, pp. 2461-2469
-
-
Sun, P.1
Quan, Z.2
Zhang, B.3
Wu, T.4
Xi, R.5
-
64
-
-
0022525029
-
Analysis of prostatic bud induction by brief androgen treatment in the fetal rat urogenital sinus
-
Takeda H., Lasnitzki I., Mizuno T. Analysis of prostatic bud induction by brief androgen treatment in the fetal rat urogenital sinus. J. Endocrinol. 1986, 3:467-470.
-
(1986)
J. Endocrinol.
, vol.3
, pp. 467-470
-
-
Takeda, H.1
Lasnitzki, I.2
Mizuno, T.3
-
65
-
-
0036499904
-
Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase
-
Tang M.J., Cai Y., Tsai S.J., Wang Y.K., Dressler G.R. Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase. Dev. Biol. 2002, 1:128-136.
-
(2002)
Dev. Biol.
, vol.1
, pp. 128-136
-
-
Tang, M.J.1
Cai, Y.2
Tsai, S.J.3
Wang, Y.K.4
Dressler, G.R.5
-
66
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor B.S., Schultz N., Hieronymus H., Gopalan A., Xiao Y., Carver B.S., Arora V.K., Kaushik P., Cerami E., Reva B., Antipin Y., Mitsiades N., Landers T., Dolgalev I., Major J.E., Wilson M., Socci N.D., Lash A.E., Heguy A., Eastham J.A., Scher H.I., Reuter V.E., Scardino P.T., Sander C., Sawyers C.L., Gerald W.L. Integrative genomic profiling of human prostate cancer. Cancer Cell 2010, 1:11-22.
-
(2010)
Cancer Cell
, vol.1
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
Arora, V.K.7
Kaushik, P.8
Cerami, E.9
Reva, B.10
Antipin, Y.11
Mitsiades, N.12
Landers, T.13
Dolgalev, I.14
Major, J.E.15
Wilson, M.16
Socci, N.D.17
Lash, A.E.18
Heguy, A.19
Eastham, J.A.20
Scher, H.I.21
Reuter, V.E.22
Scardino, P.T.23
Sander, C.24
Sawyers, C.L.25
Gerald, W.L.26
more..
-
67
-
-
0035116502
-
Role of androgens and fibroblast growth factors in prostatic development
-
Thomson A.A. Role of androgens and fibroblast growth factors in prostatic development. Reproduction 2001, 2:187-195.
-
(2001)
Reproduction
, vol.2
, pp. 187-195
-
-
Thomson, A.A.1
-
68
-
-
0032825023
-
Prostatic growth and development are regulated by FGF10
-
Thomson A.A., Cunha G.R. Prostatic growth and development are regulated by FGF10. Development 1999, 16:3693-3701.
-
(1999)
Development
, vol.16
, pp. 3693-3701
-
-
Thomson, A.A.1
Cunha, G.R.2
-
69
-
-
33747054722
-
Branching morphogenesis in the prostate gland and seminal vesicles
-
Thomson A.A., Marker P.C. Branching morphogenesis in the prostate gland and seminal vesicles. Differentiation 2006, 7:382-392.
-
(2006)
Differentiation
, vol.7
, pp. 382-392
-
-
Thomson, A.A.1
Marker, P.C.2
-
70
-
-
65549145048
-
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
-
Thoreen C.C., Kang S.A., Chang J.W., Liu Q., Zhang J., Gao Y., Reichling L.J., Sim T., Sabatini D.M., Gray N.S. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J. Biol. Chem. 2009, 12:8023-8032.
-
(2009)
J. Biol. Chem.
, vol.12
, pp. 8023-8032
-
-
Thoreen, C.C.1
Kang, S.A.2
Chang, J.W.3
Liu, Q.4
Zhang, J.5
Gao, Y.6
Reichling, L.J.7
Sim, T.8
Sabatini, D.M.9
Gray, N.S.10
-
71
-
-
0000913937
-
The culture of mature organs in a synthetic medium
-
Trowell O.A. The culture of mature organs in a synthetic medium. Exp. Cell Res. 1959, 1:118-147.
-
(1959)
Exp. Cell Res.
, vol.1
, pp. 118-147
-
-
Trowell, O.A.1
-
72
-
-
0036143774
-
Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival
-
Ueki K., Fruman D.A., Brachmann S.M., Tseng Y.H., Cantley L.C., Kahn C.R. Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival. Mol. Cell. Biol. 2002, 3:965-977.
-
(2002)
Mol. Cell. Biol.
, vol.3
, pp. 965-977
-
-
Ueki, K.1
Fruman, D.A.2
Brachmann, S.M.3
Tseng, Y.H.4
Cantley, L.C.5
Kahn, C.R.6
-
73
-
-
0346220260
-
Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling
-
Ueki K., Fruman D.A., Yballe C.M., Fasshauer M., Klein J., Asano T., Cantley L.C., Kahn C.R. Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling. J. Biol. Chem. 2003, 48:48453-48466.
-
(2003)
J. Biol. Chem.
, vol.48
, pp. 48453-48466
-
-
Ueki, K.1
Fruman, D.A.2
Yballe, C.M.3
Fasshauer, M.4
Klein, J.5
Asano, T.6
Cantley, L.C.7
Kahn, C.R.8
-
74
-
-
13444269610
-
PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung
-
Wang J., Ito T., Udaka N., Okudela K., Yazawa T., Kitamura H. PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell 2005, 1:25-35.
-
(2005)
Tissue Cell
, vol.1
, pp. 25-35
-
-
Wang, J.1
Ito, T.2
Udaka, N.3
Okudela, K.4
Yazawa, T.5
Kitamura, H.6
-
75
-
-
0037328574
-
Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures
-
Yu W., O'Brien L.E., Wang F., Bourne H., Mostov K.E., Zegers M.M. Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Mol. Biol. Cell 2003, 2:748-763.
-
(2003)
Mol. Biol. Cell
, vol.2
, pp. 748-763
-
-
Yu, W.1
O'Brien, L.E.2
Wang, F.3
Bourne, H.4
Mostov, K.E.5
Zegers, M.M.6
-
76
-
-
57349186277
-
Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis
-
Zhang J., Lin Y., Zhang Y., Lan Y., Lin C., Moon A.M., Schwartz R.J., Martin J.F., Wang F. Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. Development 2008, 21:3611-3622.
-
(2008)
Development
, vol.21
, pp. 3611-3622
-
-
Zhang, J.1
Lin, Y.2
Zhang, Y.3
Lan, Y.4
Lin, C.5
Moon, A.M.6
Schwartz, R.J.7
Martin, J.F.8
Wang, F.9
-
77
-
-
33750826279
-
The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation
-
Zhao J.J., Cheng H., Jia S., Wang L., Gjoerup O.V., Mikami A., Roberts T.M. The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation. Proc. Natl. Acad. Sci. U. S. A. 2006, 44:16296-16300.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.44
, pp. 16296-16300
-
-
Zhao, J.J.1
Cheng, H.2
Jia, S.3
Wang, L.4
Gjoerup, O.V.5
Mikami, A.6
Roberts, T.M.7
|