Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 9, Issue 2, 2006, Pages 167-181

  De La Monte, Suzanne M ^a   Wands, Jack R ^a  

^a RHODE ISLAND HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Central nervous system; Insulin resistance; Mitochondria; NADPH oxidase; Oxidative stress; Real time RT PCR

Indexed keywords

CYTOCHROME C OXIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; NEURONAL NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SOMATOMEDIN BINDING PROTEIN; SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 4; UNCOUPLING PROTEIN 5;

ALZHEIMER DISEASE; ARTICLE; BRAIN MITOCHONDRION; CLINICAL RESEARCH; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY YIELD; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FRONTAL LOBE; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN VARIANT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 33746238205     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2006-9209     Document Type: Article

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