-
1
-
-
84856433133
-
BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer’s disease: differential Abeta antibody labeling of early-onset axon terminal pathology
-
PID: 2172
-
Cai Y, Zhang XM, Macklin LN, Cai H, Luo XG, Oddo S, Laferla FM, Struble RG, Rose GM, Patrylo PR, Yan XX (2012) BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer’s disease: differential Abeta antibody labeling of early-onset axon terminal pathology. Neurotox Res 21(2):160–174. doi:10.1007/s12640-011-9256-9
-
(2012)
Neurotox Res
, vol.21
, Issue.2
, pp. 160-174
-
-
Cai, Y.1
Zhang, X.M.2
Macklin, L.N.3
Cai, H.4
Luo, X.G.5
Oddo, S.6
Laferla, F.M.7
Struble, R.G.8
Rose, G.M.9
Patrylo, P.R.10
Yan, X.X.11
-
2
-
-
77953025222
-
Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies
-
COI: 1:CAS:528:DC%2BC3cXkt1Wqs78%3D, PID: 2009
-
Ihara M, Polvikoski TM, Hall R, Slade JY, Perry RH, Oakley AE, Englund E, O’Brien JT, Ince PG, Kalaria RN (2010) Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies. Acta Neuropathol 119(5):579–589. doi:10.1007/s00401-009-0635-8
-
(2010)
Acta Neuropathol
, vol.119
, Issue.5
, pp. 579-589
-
-
Ihara, M.1
Polvikoski, T.M.2
Hall, R.3
Slade, J.Y.4
Perry, R.H.5
Oakley, A.E.6
Englund, E.7
O’Brien, J.T.8
Ince, P.G.9
Kalaria, R.N.10
-
3
-
-
78449269612
-
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease
-
COI: 1:CAS:528:DC%2BC3cXhsVGntb3K, PID: 2109
-
Hirokawa N, Niwa S, Tanaka Y (2010) Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. Neuron 68(4):610–638. doi:10.1016/j.neuron.2010.09.039
-
(2010)
Neuron
, vol.68
, Issue.4
, pp. 610-638
-
-
Hirokawa, N.1
Niwa, S.2
Tanaka, Y.3
-
4
-
-
0035809914
-
Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
-
COI: 1:CAS:528:DC%2BD3MXhslGmur4%3D, PID: 1123
-
Verhey KJ, Meyer D, Deehan R, Blenis J, Schnapp BJ, Rapoport TA, Margolis B (2001) Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J Cell Biol 152(5):959–970
-
(2001)
J Cell Biol
, vol.152
, Issue.5
, pp. 959-970
-
-
Verhey, K.J.1
Meyer, D.2
Deehan, R.3
Blenis, J.4
Schnapp, B.J.5
Rapoport, T.A.6
Margolis, B.7
-
5
-
-
0035975946
-
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein–dynactin motors
-
COI: 1:CAS:528:DC%2BD3MXot1Okt74%3D, PID: 1169
-
Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, Janssen H, Wubbolts R, Neefjes J (2001) The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein–dynactin motors. Curr Biol 11(21):1680–1685
-
(2001)
Curr Biol
, vol.11
, Issue.21
, pp. 1680-1685
-
-
Jordens, I.1
Fernandez-Borja, M.2
Marsman, M.3
Dusseljee, S.4
Janssen, L.5
Calafat, J.6
Janssen, H.7
Wubbolts, R.8
Neefjes, J.9
-
6
-
-
3042634127
-
A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons
-
COI: 1:CAS:528:DC%2BD2cXksV2htrw%3D, PID: 1515
-
Morfini G, Szebenyi G, Brown H, Pant HC, Pigino G, DeBoer S, Beffert U, Brady ST (2004) A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. EMBO J 23(11):2235–2245. doi:10.1038/sj.emboj.7600237
-
(2004)
EMBO J
, vol.23
, Issue.11
, pp. 2235-2245
-
-
Morfini, G.1
Szebenyi, G.2
Brown, H.3
Pant, H.C.4
Pigino, G.5
DeBoer, S.6
Beffert, U.7
Brady, S.T.8
-
7
-
-
0036469290
-
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
-
COI: 1:CAS:528:DC%2BD38XhsVSnsro%3D, PID: 1182
-
Morfini G, Szebenyi G, Elluru R, Ratner N, Brady ST (2002) Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J 21(3):281–293. doi:10.1093/emboj/21.3.281
-
(2002)
EMBO J
, vol.21
, Issue.3
, pp. 281-293
-
-
Morfini, G.1
Szebenyi, G.2
Elluru, R.3
Ratner, N.4
Brady, S.T.5
-
8
-
-
0035678626
-
Regulation of kinesin: implications for neuronal development
-
COI: 1:CAS:528:DC%2BD38XlsFyisA%3D%3D, PID: 1175
-
Morfini G, Szebenyi G, Richards B, Brady ST (2001) Regulation of kinesin: implications for neuronal development. Dev Neurosci 23(4–5):364–376
-
(2001)
Dev Neurosci
, vol.23
, Issue.4-5
, pp. 364-376
-
-
Morfini, G.1
Szebenyi, G.2
Richards, B.3
Brady, S.T.4
-
9
-
-
67649826155
-
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
-
COI: 1:CAS:528:DC%2BD1MXnt1Shtro%3D, PID: 1952
-
Morfini GA, You YM, Pollema SL, Kaminska A, Liu K, Yoshioka K, Bjorkblom B, Coffey ET, Bagnato C, Han D, Huang CF, Banker G, Pigino G, Brady ST (2009) Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nat Neurosci 12(7):864–871. doi:10.1038/nn.2346
-
(2009)
Nat Neurosci
, vol.12
, Issue.7
, pp. 864-871
-
-
Morfini, G.A.1
You, Y.M.2
Pollema, S.L.3
Kaminska, A.4
Liu, K.5
Yoshioka, K.6
Bjorkblom, B.7
Coffey, E.T.8
Bagnato, C.9
Han, D.10
Huang, C.F.11
Banker, G.12
Pigino, G.13
Brady, S.T.14
-
10
-
-
33745520772
-
JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport
-
COI: 1:CAS:528:DC%2BD28XmtFCmsbo%3D, PID: 1675
-
Morfini G, Pigino G, Szebenyi G, You Y, Pollema S, Brady ST (2006) JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport. Nat Neurosci 9(7):907–916. doi:10.1038/nn1717
-
(2006)
Nat Neurosci
, vol.9
, Issue.7
, pp. 907-916
-
-
Morfini, G.1
Pigino, G.2
Szebenyi, G.3
You, Y.4
Pollema, S.5
Brady, S.T.6
-
11
-
-
0030951346
-
Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue
-
COI: 1:CAS:528:DyaK2sXisFKnu7k%3D, PID: 910
-
Cross DA, Watt PW, Shaw M, van der Kaay J, Downes CP, Holder JC, Cohen P (1997) Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue. FEBS Lett 406(1–2):211–215
-
(1997)
FEBS Lett
, vol.406
, Issue.1-2
, pp. 211-215
-
-
Cross, D.A.1
Watt, P.W.2
Shaw, M.3
van der Kaay, J.4
Downes, C.P.5
Holder, J.C.6
Cohen, P.7
-
12
-
-
0029811434
-
Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C
-
COI: 1:CAS:528:DyaK28XlvV2hs7c%3D, PID: 888
-
Cook D, Fry MJ, Hughes K, Sumathipala R, Woodgett JR, Dale TC (1996) Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. EMBO J 15(17):4526–4536
-
(1996)
EMBO J
, vol.15
, Issue.17
, pp. 4526-4536
-
-
Cook, D.1
Fry, M.J.2
Hughes, K.3
Sumathipala, R.4
Woodgett, J.R.5
Dale, T.C.6
-
13
-
-
0032189798
-
A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein
-
COI: 1:CAS:528:DyaK1cXms1aktL
-
Ratner N, Bloom GS, Brady ST (1998) A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. J Neurosci Off J Soc Neurosci 18(19):7717–7726
-
(1998)
J Neurosci Off J Soc Neurosci
, vol.18
, Issue.19
, pp. 7717-7726
-
-
Ratner, N.1
Bloom, G.S.2
Brady, S.T.3
-
14
-
-
33845663953
-
Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway
-
COI: 1:CAS:528:DC%2BD28Xht1yl
-
Stagi M, Gorlovoy P, Larionov S, Takahashi K, Neumann H (2006) Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway. FASEB J Off Publ Fed Am Soc Exp Biol 20(14):2573–2575. doi:10.1096/fj.06-6679fje
-
(2006)
FASEB J Off Publ Fed Am Soc Exp Biol
, vol.20
, Issue.14
, pp. 2573-2575
-
-
Stagi, M.1
Gorlovoy, P.2
Larionov, S.3
Takahashi, K.4
Neumann, H.5
-
15
-
-
84888197384
-
Epigenetic mechanisms in Alzheimer’s disease: Implications for pathogenesis and therapy
-
COI: 1:CAS:528:DC%2BC3sXpt1Cru7k%3D, PID: 2368
-
Wang J, Yu JT, Tan MS, Jiang T, Tan L (2013) Epigenetic mechanisms in Alzheimer’s disease: Implications for pathogenesis and therapy. Ageing Res Rev 12(4):1024–1041. doi:10.1016/j.arr.2013.05.003
-
(2013)
Ageing Res Rev
, vol.12
, Issue.4
, pp. 1024-1041
-
-
Wang, J.1
Yu, J.T.2
Tan, M.S.3
Jiang, T.4
Tan, L.5
-
16
-
-
0028018919
-
Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene
-
COI: 1:STN:280:DyaK2M%2FpsVanug%3D%3D, PID: 800
-
Muller U, Cristina N, Li ZW, Wolfer DP, Lipp HP, Rulicke T, Brandner S, Aguzzi A, Weissmann C (1994) Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene. Cell 79(5):755–765
-
(1994)
Cell
, vol.79
, Issue.5
, pp. 755-765
-
-
Muller, U.1
Cristina, N.2
Li, Z.W.3
Wolfer, D.P.4
Lipp, H.P.5
Rulicke, T.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
17
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2MXhsFOqt7c%3D, PID: 1573
-
Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS (2005) Axonopathy and transport deficits early in the pathogenesis of Alzheimer’s disease. Science 307(5713):1282–1288. doi:10.1126/science.1105681
-
(2005)
Science
, vol.307
, Issue.5713
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
Brusch, R.G.4
Rockenstein, E.5
Mount, S.L.6
Raman, R.7
Davies, P.8
Masliah, E.9
Williams, D.S.10
Goldstein, L.S.11
-
18
-
-
33645764470
-
Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD28XjsFSmu7Y%3D, PID: 1652
-
Wirths O, Weis J, Szczygielski J, Multhaup G, Bayer TA (2006) Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease. Acta Neuropathol 111(4):312–319. doi:10.1007/s00401-006-0041-4
-
(2006)
Acta Neuropathol
, vol.111
, Issue.4
, pp. 312-319
-
-
Wirths, O.1
Weis, J.2
Szczygielski, J.3
Multhaup, G.4
Bayer, T.A.5
-
19
-
-
34147161245
-
In vivo axonal transport rates decrease in a mouse model of Alzheimer’s disease
-
PID: 1736
-
Smith KD, Kallhoff V, Zheng H, Pautler RG (2007) In vivo axonal transport rates decrease in a mouse model of Alzheimer’s disease. NeuroImage 35(4):1401–1408. doi:10.1016/j.neuroimage.2007.01.046
-
(2007)
NeuroImage
, vol.35
, Issue.4
, pp. 1401-1408
-
-
Smith, K.D.1
Kallhoff, V.2
Zheng, H.3
Pautler, R.G.4
-
20
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
-
COI: 1:CAS:528:DC%2BD3cXoslaisLc%3D, PID: 1114
-
Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS (2000) Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28(2):449–459
-
(2000)
Neuron
, vol.28
, Issue.2
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
21
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
-
COI: 1:STN:280:DC%2BD3MjgtFCktQ%3D%3D, PID: 1174
-
Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LS (2001) Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature 414(6864):643–648. doi:10.1038/414643a
-
(2001)
Nature
, vol.414
, Issue.6864
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
22
-
-
27944444156
-
Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1
-
COI: 1:CAS:528:DC%2BD2MXht1KgtLzE, PID: 1630
-
Muresan Z, Muresan V (2005) Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. J Cell Biol 171(4):615–625. doi:10.1083/jcb.200502043
-
(2005)
J Cell Biol
, vol.171
, Issue.4
, pp. 615-625
-
-
Muresan, Z.1
Muresan, V.2
-
23
-
-
33846007738
-
PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2
-
COI: 1:CAS:528:DC%2BD28XhtlCrt7%2FJ, PID: 1705
-
Kuan YH, Gruebl T, Soba P, Eggert S, Nesic I, Back S, Kirsch J, Beyreuther K, Kins S (2006) PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2. J Biol Chem 281(52):40114–40123. doi:10.1074/jbc.M605407200
-
(2006)
J Biol Chem
, vol.281
, Issue.52
, pp. 40114-40123
-
-
Kuan, Y.H.1
Gruebl, T.2
Soba, P.3
Eggert, S.4
Nesic, I.5
Back, S.6
Kirsch, J.7
Beyreuther, K.8
Kins, S.9
-
24
-
-
33947607769
-
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport
-
COI: 1:CAS:528:DC%2BD2sXjt1Wktrw%3D, PID: 1733
-
Araki Y, Kawano T, Taru H, Saito Y, Wada S, Miyamoto K, Kobayashi H, Ishikawa HO, Ohsugi Y, Yamamoto T, Matsuno K, Kinjo M, Suzuki T (2007) The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J 26(6):1475–1486. doi:10.1038/sj.emboj.7601609
-
(2007)
EMBO J
, vol.26
, Issue.6
, pp. 1475-1486
-
-
Araki, Y.1
Kawano, T.2
Taru, H.3
Saito, Y.4
Wada, S.5
Miyamoto, K.6
Kobayashi, H.7
Ishikawa, H.O.8
Ohsugi, Y.9
Yamamoto, T.10
Matsuno, K.11
Kinjo, M.12
Suzuki, T.13
-
25
-
-
84863518335
-
Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Abeta production
-
COI: 1:CAS:528:DC%2BC38Xos1yltb8%3D, PID: 2243
-
Vagnoni A, Perkinton MS, Gray EH, Francis PT, Noble W, Miller CC (2012) Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Abeta production. Hum Mol Genet 21(13):2845–2854. doi:10.1093/hmg/dds109
-
(2012)
Hum Mol Genet
, vol.21
, Issue.13
, pp. 2845-2854
-
-
Vagnoni, A.1
Perkinton, M.S.2
Gray, E.H.3
Francis, P.T.4
Noble, W.5
Miller, C.C.6
-
26
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited
-
COI: 1:CAS:528:DC%2BD2MXisVOmtL
-
Lazarov O, Morfini GA, Lee EB, Farah MH, Szodorai A, DeBoer SR, Koliatsos VE, Kins S, Lee VM, Wong PC, Price DL, Brady ST, Sisodia SS (2005) Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. J Neurosci Off J Soc Neurosci 25(9):2386–2395. doi:10.1523/JNEUROSCI.3089-04.2005
-
(2005)
J Neurosci Off J Soc Neurosci
, vol.25
, Issue.9
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodorai, A.5
DeBoer, S.R.6
Koliatsos, V.E.7
Kins, S.8
Lee, V.M.9
Wong, P.C.10
Price, D.L.11
Brady, S.T.12
Sisodia, S.S.13
-
27
-
-
84887005627
-
Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Abeta production
-
COI: 1:CAS:528:DC%2BC3sXhs1yitrrL, PID: 2382
-
Vagnoni A, Glennon EB, Perkinton MS, Gray EH, Noble W, Miller CC (2013) Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Abeta production. Hum Mol Genet 22(22):4646–4652. doi:10.1093/hmg/ddt313
-
(2013)
Hum Mol Genet
, vol.22
, Issue.22
, pp. 4646-4652
-
-
Vagnoni, A.1
Glennon, E.B.2
Perkinton, M.S.3
Gray, E.H.4
Noble, W.5
Miller, C.C.6
-
28
-
-
84873477336
-
Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein
-
COI: 1:CAS:528:DC%2BC3sXlsV2it7g%3D, PID: 2327
-
Weaver C, Leidel C, Szpankowski L, Farley NM, Shubeita GT, Goldstein LS (2013) Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic 14(3):295–308. doi:10.1111/tra.12037
-
(2013)
Traffic
, vol.14
, Issue.3
, pp. 295-308
-
-
Weaver, C.1
Leidel, C.2
Szpankowski, L.3
Farley, N.M.4
Shubeita, G.T.5
Goldstein, L.S.6
-
29
-
-
84867766569
-
Enhanced beta-secretase processing alters APP axonal transport and leads to axonal defects
-
COI: 1:CAS:528:DC%2BC38XhsFCgsLnJ, PID: 2284
-
Rodrigues EM, Weissmiller AM, Goldstein LS (2012) Enhanced beta-secretase processing alters APP axonal transport and leads to axonal defects. Hum Mol Genet 21(21):4587–4601. doi:10.1093/hmg/dds297
-
(2012)
Hum Mol Genet
, vol.21
, Issue.21
, pp. 4587-4601
-
-
Rodrigues, E.M.1
Weissmiller, A.M.2
Goldstein, L.S.3
-
30
-
-
33745512851
-
Increased App expression in a mouse model of Down’s syndrome disrupts NGF transport and causes cholinergic neuron degeneration
-
COI: 1:CAS:528:DC%2BD28XnsVWgsrY%3D, PID: 1681
-
Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC (2006) Increased App expression in a mouse model of Down’s syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron 51(1):29–42. doi:10.1016/j.neuron.2006.05.022
-
(2006)
Neuron
, vol.51
, Issue.1
, pp. 29-42
-
-
Salehi, A.1
Delcroix, J.D.2
Belichenko, P.V.3
Zhan, K.4
Wu, C.5
Valletta, J.S.6
Takimoto-Kimura, R.7
Kleschevnikov, A.M.8
Sambamurti, K.9
Chung, P.P.10
Xia, W.11
Villar, A.12
Campbell, W.A.13
Kulnane, L.S.14
Nixon, R.A.15
Lamb, B.T.16
Epstein, C.J.17
Stokin, G.B.18
Goldstein, L.S.19
Mobley, W.C.20
more..
-
31
-
-
33750823234
-
A peptide zipcode sufficient for anterograde transport within amyloid precursor protein
-
COI: 1:CAS:528:DC%2BD28Xht1WmsLnF, PID: 1706
-
Satpute-Krishnan P, DeGiorgis JA, Conley MP, Jang M, Bearer EL (2006) A peptide zipcode sufficient for anterograde transport within amyloid precursor protein. Proc Natl Acad Sci U S A 103(44):16532–16537. doi:10.1073/pnas.0607527103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.44
, pp. 16532-16537
-
-
Satpute-Krishnan, P.1
DeGiorgis, J.A.2
Conley, M.P.3
Jang, M.4
Bearer, E.L.5
-
32
-
-
77950632324
-
Abeta promotes Alzheimer’s disease-like cytoskeleton abnormalities with consequences to APP processing in neurons
-
COI: 1:CAS:528:DC%2BC3cXls1amtbc%3D, PID: 2034
-
Henriques AG, Vieira SI, da Cruz ESEF, da Cruz ESOA (2010) Abeta promotes Alzheimer’s disease-like cytoskeleton abnormalities with consequences to APP processing in neurons. J Neurochem 113(3):761–771. doi:10.1111/j.1471-4159.2010.06643.x
-
(2010)
J Neurochem
, vol.113
, Issue.3
, pp. 761-771
-
-
Henriques, A.G.1
Vieira, S.I.2
da Cruz, E.S.E.F.3
da Cruz, E.S.O.A.4
-
33
-
-
49549083278
-
Histone deacetylase 6 interacts with the microtubule-associated protein tau
-
COI: 1:CAS:528:DC%2BD1cXhtV2rt7fM, PID: 1863
-
Ding H, Dolan PJ, Johnson GV (2008) Histone deacetylase 6 interacts with the microtubule-associated protein tau. J Neurochem 106(5):2119–2130. doi:10.1111/j.1471-4159.2008.05564.x
-
(2008)
J Neurochem
, vol.106
, Issue.5
, pp. 2119-2130
-
-
Ding, H.1
Dolan, P.J.2
Johnson, G.V.3
-
34
-
-
0141864562
-
Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms
-
COI: 1:CAS:528:DC%2BD3sXotFOnur
-
Hiruma H, Katakura T, Takahashi S, Ichikawa T, Kawakami T (2003) Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms. J Neurosci Off J Soc Neurosci 23(26):8967–8977
-
(2003)
J Neurosci Off J Soc Neurosci
, vol.23
, Issue.26
, pp. 8967-8977
-
-
Hiruma, H.1
Katakura, T.2
Takahashi, S.3
Ichikawa, T.4
Kawakami, T.5
-
35
-
-
33748306219
-
2+ oscillations in cultured hippocampal networks
-
COI: 1:CAS:528:DC%2BD28XpsVOmtbg%3D, PID: 1679
-
2+ oscillations in cultured hippocampal networks. Cell Biol Int 30(9):733–740. doi:10.1016/j.cellbi.2006.05.005
-
(2006)
Cell Biol Int
, vol.30
, Issue.9
, pp. 733-740
-
-
Rui, Y.1
Li, R.2
Liu, Y.3
Zhu, S.4
Yu, X.5
Sheng, Z.6
Xie, Z.7
-
36
-
-
84859726053
-
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease- associated Abeta oligomers
-
COI: 1:CAS:528:DC%2BC38Xlt1egtbc%3D, PID: 2247
-
Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG (2012) An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease- associated Abeta oligomers. J Clin Invest 122(4):1339–1353. doi:10.1172/JCI57256
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1339-1353
-
-
Bomfim, T.R.1
Forny-Germano, L.2
Sathler, L.B.3
Brito-Moreira, J.4
Houzel, J.C.5
Decker, H.6
Silverman, M.A.7
Kazi, H.8
Melo, H.M.9
McClean, P.L.10
Holscher, C.11
Arnold, S.E.12
Talbot, K.13
Klein, W.L.14
Munoz, D.P.15
Ferreira, S.T.16
De Felice, F.G.17
-
37
-
-
65249161745
-
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta
-
COI: 1:CAS:528:DC%2BD1MXkvFehtro%3D, PID: 1932
-
Pigino G, Morfini G, Atagi Y, Deshpande A, Yu C, Jungbauer L, LaDu M, Busciglio J, Brady S (2009) Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta. Proc Natl Acad Sci U S A 106(14):5907–5912. doi:10.1073/pnas.0901229106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.14
, pp. 5907-5912
-
-
Pigino, G.1
Morfini, G.2
Atagi, Y.3
Deshpande, A.4
Yu, C.5
Jungbauer, L.6
LaDu, M.7
Busciglio, J.8
Brady, S.9
-
38
-
-
77954466407
-
Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons
-
COI: 1:CAS:528:DC%2BC3cXpt1yisb
-
Decker H, Lo KY, Unger SM, Ferreira ST, Silverman MA (2010) Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons. J Neurosci Off J Soc Neurosci 30(27):9166–9171. doi:10.1523/JNEUROSCI.1074-10.2010
-
(2010)
J Neurosci Off J Soc Neurosci
, vol.30
, Issue.27
, pp. 9166-9171
-
-
Decker, H.1
Lo, K.Y.2
Unger, S.M.3
Ferreira, S.T.4
Silverman, M.A.5
-
39
-
-
77956587739
-
Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines
-
COI: 1:CAS:528:DC%2BC3cXhtF2q
-
Zempel H, Thies E, Mandelkow E, Mandelkow EM (2010) Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci Off J Soc Neurosci 30(36):11938–11950. doi:10.1523/JNEUROSCI.2357-10.2010
-
(2010)
J Neurosci Off J Soc Neurosci
, vol.30
, Issue.36
, pp. 11938-11950
-
-
Zempel, H.1
Thies, E.2
Mandelkow, E.3
Mandelkow, E.M.4
-
40
-
-
13144265717
-
Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau
-
COI: 1:CAS:528:DyaK1cXltlCltr0%3D, PID: 968
-
Takashima A, Murayama M, Murayama O, Kohno T, Honda T, Yasutake K, Nihonmatsu N, Mercken M, Yamaguchi H, Sugihara S, Wolozin B (1998) Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proc Natl Acad Sci U S A 95(16):9637–9641
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.16
, pp. 9637-9641
-
-
Takashima, A.1
Murayama, M.2
Murayama, O.3
Kohno, T.4
Honda, T.5
Yasutake, K.6
Nihonmatsu, N.7
Mercken, M.8
Yamaguchi, H.9
Sugihara, S.10
Wolozin, B.11
-
41
-
-
0034534014
-
GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations
-
COI: 1:CAS:528:DC%2BD3MXotlaisA%3D%3D, PID: 1119
-
Tesco G, Tanzi RE (2000) GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations. Ann N Y Acad Sci 920:227–232
-
(2000)
Ann N Y Acad Sci
, vol.920
, pp. 227-232
-
-
Tesco, G.1
Tanzi, R.E.2
-
42
-
-
0038118207
-
Alzheimer’s presenilin 1 mutations impair kinesin-based axonal transport
-
COI: 1:CAS:528:DC%2BD3sXkslOksr
-
Pigino G, Morfini G, Pelsman A, Mattson MP, Brady ST, Busciglio J (2003) Alzheimer’s presenilin 1 mutations impair kinesin-based axonal transport. J Neurosci Off J Soc Neurosci 23(11):4499–4508
-
(2003)
J Neurosci Off J Soc Neurosci
, vol.23
, Issue.11
, pp. 4499-4508
-
-
Pigino, G.1
Morfini, G.2
Pelsman, A.3
Mattson, M.P.4
Brady, S.T.5
Busciglio, J.6
-
43
-
-
34347353311
-
Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer’s disease-linked mutant presenilin 1
-
COI: 1:CAS:528:DC%2BD2sXnsVyjt7
-
Lazarov O, Morfini GA, Pigino G, Gadadhar A, Chen X, Robinson J, Ho H, Brady ST, Sisodia SS (2007) Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer’s disease-linked mutant presenilin 1. J Neurosci Off J Soc Neurosci 27(26):7011–7020. doi:10.1523/JNEUROSCI.4272-06.2007
-
(2007)
J Neurosci Off J Soc Neurosci
, vol.27
, Issue.26
, pp. 7011-7020
-
-
Lazarov, O.1
Morfini, G.A.2
Pigino, G.3
Gadadhar, A.4
Chen, X.5
Robinson, J.6
Ho, H.7
Brady, S.T.8
Sisodia, S.S.9
-
44
-
-
84894086136
-
Presenilin influences glycogen synthase kinase-3 beta (GSK-3beta) for kinesin-1 and dynein function during axonal transport
-
COI: 1:CAS:528:DC%2BC2cXitFWiurw%3D, PID: 2410
-
Dolma K, Iacobucci GJ, Hong Zheng K, Shandilya J, Toska E, White JA 2nd, Spina E, Gunawardena S (2014) Presenilin influences glycogen synthase kinase-3 beta (GSK-3beta) for kinesin-1 and dynein function during axonal transport. Hum Mol Genet 23(5):1121–1133. doi:10.1093/hmg/ddt505
-
(2014)
Hum Mol Genet
, vol.23
, Issue.5
, pp. 1121-1133
-
-
Dolma, K.1
Iacobucci, G.J.2
Hong Zheng, K.3
Shandilya, J.4
Toska, E.5
White, J.A.6
Spina, E.7
Gunawardena, S.8
-
45
-
-
0022550260
-
Defective brain microtubule assembly in Alzheimer’s disease
-
COI: 1:CAS:528:DyaL28XlsFSrur0%3D, PID: 287
-
Iqbal K, Grundke-Iqbal I, Zaidi T, Merz PA, Wen GY, Shaikh SS, Wisniewski HM, Alafuzoff I, Winblad B (1986) Defective brain microtubule assembly in Alzheimer’s disease. Lancet 2(8504):421–426
-
(1986)
Lancet
, vol.2
, Issue.8504
, pp. 421-426
-
-
Iqbal, K.1
Grundke-Iqbal, I.2
Zaidi, T.3
Merz, P.A.4
Wen, G.Y.5
Shaikh, S.S.6
Wisniewski, H.M.7
Alafuzoff, I.8
Winblad, B.9
-
46
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
COI: 1:CAS:528:DyaL28XksFyqtrg%3D, PID: 308
-
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI (1986) Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci U S A 83(13):4913–4917
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, Issue.13
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
47
-
-
0027308924
-
Abnormal tau phosphorylation at Ser396 in Alzheimer’s disease recapitulates development and contributes to reduced microtubule binding
-
COI: 1:CAS:528:DyaK3sXmsVOitL8%3D, PID: 831
-
Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee VM (1993) Abnormal tau phosphorylation at Ser396 in Alzheimer’s disease recapitulates development and contributes to reduced microtubule binding. Neuron 10(6):1089–1099
-
(1993)
Neuron
, vol.10
, Issue.6
, pp. 1089-1099
-
-
Bramblett, G.T.1
Goedert, M.2
Jakes, R.3
Merrick, S.E.4
Trojanowski, J.Q.5
Lee, V.M.6
-
48
-
-
0033042978
-
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation
-
COI: 1:CAS:528:DyaK1MXhvVCmtLw%3D, PID: 1010
-
Dayanandan R, Van Slegtenhorst M, Mack TG, Ko L, Yen SH, Leroy K, Brion JP, Anderton BH, Hutton M, Lovestone S (1999) Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation. FEBS Lett 446(2–3):228–232
-
(1999)
FEBS Lett
, vol.446
, Issue.2-3
, pp. 228-232
-
-
Dayanandan, R.1
Van Slegtenhorst, M.2
Mack, T.G.3
Ko, L.4
Yen, S.H.5
Leroy, K.6
Brion, J.P.7
Anderton, B.H.8
Hutton, M.9
Lovestone, S.10
-
49
-
-
3142592230
-
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
-
COI: 1:CAS:528:DC%2BD2cXjsV2nu78%3D, PID: 1499
-
Mudher A, Shepherd D, Newman TA, Mildren P, Jukes JP, Squire A, Mears A, Drummond JA, Berg S, MacKay D, Asuni AA, Bhat R, Lovestone S (2004) GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Mol Psychiatry 9(5):522–530. doi:10.1038/sj.mp.4001483
-
(2004)
Mol Psychiatry
, vol.9
, Issue.5
, pp. 522-530
-
-
Mudher, A.1
Shepherd, D.2
Newman, T.A.3
Mildren, P.4
Jukes, J.P.5
Squire, A.6
Mears, A.7
Drummond, J.A.8
Berg, S.9
MacKay, D.10
Asuni, A.A.11
Bhat, R.12
Lovestone, S.13
-
50
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
COI: 1:CAS:528:DyaK1MXnvFyjsrg%3D, PID: 1059
-
Ishihara T, Hong M, Zhang B, Nakagawa Y, Lee MK, Trojanowski JQ, Lee VM (1999) Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron 24(3):751–762
-
(1999)
Neuron
, vol.24
, Issue.3
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.7
-
51
-
-
26844433190
-
Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies
-
COI: 1:CAS:528:DC%2BD2MXhtFGm
-
Higuchi M, Zhang B, Forman MS, Yoshiyama Y, Trojanowski JQ, Lee VM (2005) Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies. J Neurosci Off J Soc Neurosci 25(41):9434–9443. doi:10.1523/JNEUROSCI.2691-05.2005
-
(2005)
J Neurosci Off J Soc Neurosci
, vol.25
, Issue.41
, pp. 9434-9443
-
-
Higuchi, M.1
Zhang, B.2
Forman, M.S.3
Yoshiyama, Y.4
Trojanowski, J.Q.5
Lee, V.M.6
-
52
-
-
0036008557
-
Coexpression of GSK-3beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau
-
COI: 1:CAS:528:DC%2BD38Xht1GnsL0%3D, PID: 1184
-
Nuydens R, Van Den Kieboom G, Nolten C, Verhulst C, Van Osta P, Spittaels K, Van den Haute C, De Feyter E, Geerts H, Van Leuven F (2002) Coexpression of GSK-3beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau. Neurobiol Dis 9(1):38–48. doi:10.1006/nbdi.2001.0454
-
(2002)
Neurobiol Dis
, vol.9
, Issue.1
, pp. 38-48
-
-
Nuydens, R.1
Van Den Kieboom, G.2
Nolten, C.3
Verhulst, C.4
Van Osta, P.5
Spittaels, K.6
Van den Haute, C.7
De Feyter, E.8
Geerts, H.9
Van Leuven, F.10
-
53
-
-
84859348885
-
Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau
-
COI: 1:CAS:528:DC%2BC38Xlslejur8%3D, PID: 2249
-
Bull ND, Guidi A, Goedert M, Martin KR, Spillantini MG (2012) Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau. PLoS One 7(4):e34724. doi:10.1371/journal.pone.0034724
-
(2012)
PLoS One
, vol.7
, Issue.4
, pp. 34724
-
-
Bull, N.D.1
Guidi, A.2
Goedert, M.3
Martin, K.R.4
Spillantini, M.G.5
-
54
-
-
2442642836
-
Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy
-
COI: 1:CAS:528:DC%2BD2cXksFCqur
-
Zhang B, Higuchi M, Yoshiyama Y, Ishihara T, Forman MS, Martinez D, Joyce S, Trojanowski JQ, Lee VM (2004) Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy. J Neurosci Off J Soc Neurosci 24(19):4657–4667. doi:10.1523/JNEUROSCI.0797-04.2004
-
(2004)
J Neurosci Off J Soc Neurosci
, vol.24
, Issue.19
, pp. 4657-4667
-
-
Zhang, B.1
Higuchi, M.2
Yoshiyama, Y.3
Ishihara, T.4
Forman, M.S.5
Martinez, D.6
Joyce, S.7
Trojanowski, J.Q.8
Lee, V.M.9
-
55
-
-
0037119947
-
Single-molecule investigation of the interference between kinesin, tau and MAP2c
-
COI: 1:CAS:528:DC%2BD38Xnt1Gnt7g%3D, PID: 1223
-
Seitz A, Kojima H, Oiwa K, Mandelkow EM, Song YH, Mandelkow E (2002) Single-molecule investigation of the interference between kinesin, tau and MAP2c. EMBO J 21(18):4896–4905
-
(2002)
EMBO J
, vol.21
, Issue.18
, pp. 4896-4905
-
-
Seitz, A.1
Kojima, H.2
Oiwa, K.3
Mandelkow, E.M.4
Song, Y.H.5
Mandelkow, E.6
-
56
-
-
79960032374
-
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases
-
COI: 1:CAS:528:DC%2BC3MXptFWrur
-
Kanaan NM, Morfini GA, LaPointe NE, Pigino GF, Patterson KR, Song Y, Andreadis A, Fu Y, Brady ST, Binder LI (2011) Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases. J Neurosci Off J Soc Neurosci 31(27):9858–9868. doi:10.1523/JNEUROSCI.0560-11.2011
-
(2011)
J Neurosci Off J Soc Neurosci
, vol.31
, Issue.27
, pp. 9858-9868
-
-
Kanaan, N.M.1
Morfini, G.A.2
LaPointe, N.E.3
Pigino, G.F.4
Patterson, K.R.5
Song, Y.6
Andreadis, A.7
Fu, Y.8
Brady, S.T.9
Binder, L.I.10
-
57
-
-
34250317264
-
Tau binding to microtubules does not directly affect microtubule-based vesicle motility
-
COI: 1:CAS:528:DC%2BD2sXht1Wntr%2FI, PID: 1726
-
Morfini G, Pigino G, Mizuno N, Kikkawa M, Brady ST (2007) Tau binding to microtubules does not directly affect microtubule-based vesicle motility. J Neurosci Res 85(12):2620–2630. doi:10.1002/jnr.21154
-
(2007)
J Neurosci Res
, vol.85
, Issue.12
, pp. 2620-2630
-
-
Morfini, G.1
Pigino, G.2
Mizuno, N.3
Kikkawa, M.4
Brady, S.T.5
-
58
-
-
62849088641
-
The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity
-
COI: 1:CAS:528:DC%2BD1MXhvFCrsLs%3D, PID: 1879
-
LaPointe NE, Morfini G, Pigino G, Gaisina IN, Kozikowski AP, Binder LI, Brady ST (2009) The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. J Neurosci Res 87(2):440–451. doi:10.1002/jnr.21850
-
(2009)
J Neurosci Res
, vol.87
, Issue.2
, pp. 440-451
-
-
LaPointe, N.E.1
Morfini, G.2
Pigino, G.3
Gaisina, I.N.4
Kozikowski, A.P.5
Binder, L.I.6
Brady, S.T.7
-
59
-
-
35649028013
-
Interaction of tau protein with the dynactin complex
-
COI: 1:CAS:528:DC%2BD2sXht1emtbjM, PID: 1793
-
Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA, Spillantini MG (2007) Interaction of tau protein with the dynactin complex. EMBO J 26(21):4546–4554. doi:10.1038/sj.emboj.7601878
-
(2007)
EMBO J
, vol.26
, Issue.21
, pp. 4546-4554
-
-
Magnani, E.1
Fan, J.2
Gasparini, L.3
Golding, M.4
Williams, M.5
Schiavo, G.6
Goedert, M.7
Amos, L.A.8
Spillantini, M.G.9
-
60
-
-
68949105821
-
Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease
-
COI: 1:CAS:528:DC%2BD1MXovFWrtLg%3D, PID: 1949
-
Ittner LM, Ke YD, Gotz J (2009) Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. J Biol Chem 284(31):20909–20916. doi:10.1074/jbc.M109.014472
-
(2009)
J Biol Chem
, vol.284
, Issue.31
, pp. 20909-20916
-
-
Ittner, L.M.1
Ke, Y.D.2
Gotz, J.3
-
61
-
-
79952897585
-
Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability
-
COI: 1:CAS:528:DC%2BC3MXjvVOqsLk%3D, PID: 1935
-
Gasparini L, Crowther RA, Martin KR, Berg N, Coleman M, Goedert M, Spillantini MG (2011) Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability. Neurobiol Aging 32(3):419–433. doi:10.1016/j.neurobiolaging.2009.03.002
-
(2011)
Neurobiol Aging
, vol.32
, Issue.3
, pp. 419-433
-
-
Gasparini, L.1
Crowther, R.A.2
Martin, K.R.3
Berg, N.4
Coleman, M.5
Goedert, M.6
Spillantini, M.G.7
-
62
-
-
84892690719
-
Global axonal transport rates are unaltered in htau mice invivo
-
Yuan A, Kumar A, Sasaki T, Duff K, Nixon RA (2013) Global axonal transport rates are unaltered in htau mice invivo. J Alzheimer’s Dis 37(3):579–586. doi:10.3233/JAD-130671
-
(2013)
J Alzheimer’s Dis
, vol.37
, Issue.3
, pp. 579-586
-
-
Yuan, A.1
Kumar, A.2
Sasaki, T.3
Duff, K.4
Nixon, R.A.5
-
63
-
-
84898833069
-
Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice
-
COI: 1:CAS:528:DC%2BC2cXhvVWqtLc%3D, PID: 2440
-
Onishi T, Matsumoto Y, Hattori M, Obayashi Y, Nakamura K, Yano T, Horiguchi T, Iwashita H (2014) Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice. Neurosci Res 80:76–85. doi:10.1016/j.neures.2013.12.006
-
(2014)
Neurosci Res
, vol.80
, pp. 76-85
-
-
Onishi, T.1
Matsumoto, Y.2
Hattori, M.3
Obayashi, Y.4
Nakamura, K.5
Yano, T.6
Horiguchi, T.7
Iwashita, H.8
-
64
-
-
34247172582
-
Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival
-
COI: 1:CAS:528:DC%2BD2sXhvVaitrY%3D, PID: 1716
-
Tal R, Winter G, Ecker N, Klionsky DJ, Abeliovich H (2007) Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. J Biol Chem 282(8):5617–5624. doi:10.1074/jbc.M605940200
-
(2007)
J Biol Chem
, vol.282
, Issue.8
, pp. 5617-5624
-
-
Tal, R.1
Winter, G.2
Ecker, N.3
Klionsky, D.J.4
Abeliovich, H.5
-
65
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD1MXovFegu7
-
Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer’s disease. J Neurosci Off J Soc Neurosci 29(28):9090–9103. doi:10.1523/JNEUROSCI.1357-09.2009
-
(2009)
J Neurosci Off J Soc Neurosci
, vol.29
, Issue.28
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
Perry, G.5
Smith, M.A.6
Zhu, X.7
-
66
-
-
84878623135
-
Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXotFagtb
-
Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI (2013) Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer’s disease. Curr Alzheimers Res 10(4):406–419
-
(2013)
Curr Alzheimers Res
, vol.10
, Issue.4
, pp. 406-419
-
-
Correia, S.C.1
Santos, R.X.2
Santos, M.S.3
Casadesus, G.4
Lamanna, J.C.5
Perry, G.6
Smith, M.A.7
Moreira, P.I.8
-
67
-
-
0025217385
-
Quantitative assessment of cortical synaptic density in Alzheimer’s disease
-
COI: 1:STN:280:DyaK3c3itFShug%3D%3D, PID: 232
-
Scheff SW, DeKosky ST, Price DA (1990) Quantitative assessment of cortical synaptic density in Alzheimer’s disease. Neurobiol Aging 11(1):29–37
-
(1990)
Neurobiol Aging
, vol.11
, Issue.1
, pp. 29-37
-
-
Scheff, S.W.1
DeKosky, S.T.2
Price, D.A.3
-
68
-
-
33749854516
-
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons
-
COI: 1:CAS:528:DC%2BD28XhtFegur
-
Rui Y, Tiwari P, Xie Z, Zheng JQ (2006) Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons. J Neurosci Off J Soc Neurosci 26(41):10480–10487. doi:10.1523/JNEUROSCI.3231-06.2006
-
(2006)
J Neurosci Off J Soc Neurosci
, vol.26
, Issue.41
, pp. 10480-10487
-
-
Rui, Y.1
Tiwari, P.2
Xie, Z.3
Zheng, J.Q.4
-
69
-
-
79751537405
-
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer’s disease neurons
-
COI: 1:CAS:528:DC%2BC3MXit1ynt7c%3D, PID: 2124
-
Calkins MJ, Reddy PH (2011) Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer’s disease neurons. Biochim Biophys Acta 1812(4):507–513. doi:10.1016/j.bbadis.2011.01.007
-
(2011)
Biochim Biophys Acta
, vol.1812
, Issue.4
, pp. 507-513
-
-
Calkins, M.J.1
Reddy, P.H.2
-
70
-
-
75349092711
-
Expression of beta-amyloid induced age-dependent presynaptic and axonal changes in Drosophila
-
COI: 1:CAS:528:DC%2BC3cXhsVOqsr
-
Zhao XL, Wang WA, Tan JX, Huang JK, Zhang X, Zhang BZ, Wang YH, YangCheng HY, Zhu HL, Sun XJ, Huang FD (2010) Expression of beta-amyloid induced age-dependent presynaptic and axonal changes in Drosophila. J Neurosci Off J Soc Neurosci 30(4):1512–1522. doi:10.1523/JNEUROSCI.3699-09.2010
-
(2010)
J Neurosci Off J Soc Neurosci
, vol.30
, Issue.4
, pp. 1512-1522
-
-
Zhao, X.L.1
Wang, W.A.2
Tan, J.X.3
Huang, J.K.4
Zhang, X.5
Zhang, B.Z.6
Wang, Y.H.7
YangCheng, H.Y.8
Zhu, H.L.9
Sun, X.J.10
Huang, F.D.11
-
71
-
-
78649815388
-
Early deficits in synaptic mitochondria in an Alzheimer’s disease mouse model
-
COI: 1:CAS:528:DC%2BC3cXhtl2lsr7E, PID: 2093
-
Du H, Guo L, Yan S, Sosunov AA, McKhann GM, Yan SS (2010) Early deficits in synaptic mitochondria in an Alzheimer’s disease mouse model. Proc Natl Acad Sci U S A 107(43):18670–18675. doi:10.1073/pnas.1006586107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.43
, pp. 18670-18675
-
-
Du, H.1
Guo, L.2
Yan, S.3
Sosunov, A.A.4
McKhann, G.M.5
Yan, S.S.6
-
72
-
-
84865179881
-
HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons
-
COI: 1:CAS:528:DC%2BC38Xht1GqsbzI, PID: 2293
-
Kim C, Choi H, Jung ES, Lee W, Oh S, Jeon NL, Mook-Jung I (2012) HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons. PLoS One 7(8):e42983. doi:10.1371/journal.pone.0042983
-
(2012)
PLoS One
, vol.7
, Issue.8
, pp. 42983
-
-
Kim, C.1
Choi, H.2
Jung, E.S.3
Lee, W.4
Oh, S.5
Jeon, N.L.6
Mook-Jung, I.7
-
73
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer’s disease brain is associated with mitochondrial dysfunction
-
COI: 1:CAS:528:DC%2BD28Xpt1aqu7
-
Devi L, Prabhu BM, Galati DF, Avadhani NG, Anandatheerthavarada HK (2006) Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer’s disease brain is associated with mitochondrial dysfunction. J Neurosci Off J Soc Neurosci 26(35):9057–9068. doi:10.1523/JNEUROSCI.1469-06.2006
-
(2006)
J Neurosci Off J Soc Neurosci
, vol.26
, Issue.35
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
74
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD1cXht1Slu7vJ, PID: 1880
-
Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM, Yan Y, Wang C, Zhang H, Molkentin JD, Gunn-Moore FJ, Vonsattel JP, Arancio O, Chen JX, Yan SD (2008) Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer’s disease. Nat Med 14(10):1097–1105. doi:10.1038/nm.1868
-
(2008)
Nat Med
, vol.14
, Issue.10
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
Yan, Y.7
Wang, C.8
Zhang, H.9
Molkentin, J.D.10
Gunn-Moore, F.J.11
Vonsattel, J.P.12
Arancio, O.13
Chen, J.X.14
Yan, S.D.15
-
75
-
-
33646152108
-
Mitochondria are a direct site of A beta accumulation in Alzheimer’s disease neurons: implications for free radical generation and oxidative damage in disease progression
-
COI: 1:CAS:528:DC%2BD28XjslGhsLs%3D, PID: 1655
-
Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Reddy PH (2006) Mitochondria are a direct site of A beta accumulation in Alzheimer’s disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum Mol Genet 15(9):1437–1449. doi:10.1093/hmg/ddl066
-
(2006)
Hum Mol Genet
, vol.15
, Issue.9
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
76
-
-
28744449206
-
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2MXhtlSm
-
Caspersen C, Wang N, Yao J, Sosunov A, Chen X, Lustbader JW, Xu HW, Stern D, McKhann G, Yan SD (2005) Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer’s disease. FASEB J Off Publ Fed Am Soc Exp Biol 19(14):2040–2041. doi:10.1096/fj.05-3735fje
-
(2005)
FASEB J Off Publ Fed Am Soc Exp Biol
, vol.19
, Issue.14
, pp. 2040-2041
-
-
Caspersen, C.1
Wang, N.2
Yao, J.3
Sosunov, A.4
Chen, X.5
Lustbader, J.W.6
Xu, H.W.7
Stern, D.8
McKhann, G.9
Yan, S.D.10
-
77
-
-
77649233060
-
Regulation of axonal trafficking of cytochrome c oxidase IV mRNA
-
COI: 1:CAS:528:DC%2BC3cXjtVSgtr4%3D, PID: 2014
-
Aschrafi A, Natera-Naranjo O, Gioio AE, Kaplan BB (2010) Regulation of axonal trafficking of cytochrome c oxidase IV mRNA. Mol Cell Neurosci 43(4):422–430. doi:10.1016/j.mcn.2010.01.009
-
(2010)
Mol Cell Neurosci
, vol.43
, Issue.4
, pp. 422-430
-
-
Aschrafi, A.1
Natera-Naranjo, O.2
Gioio, A.E.3
Kaplan, B.B.4
-
78
-
-
77954979874
-
The mitochondrial secret(ase) of Alzheimer’s disease
-
Young KJ, Bennett JP (2010) The mitochondrial secret(ase) of Alzheimer’s disease. J Alzheimer’s Dis 20(Suppl 2):S381–S400. doi:10.3233/JAD-2010-100360
-
(2010)
J Alzheimer’s Dis
, vol.20
, pp. 381-400
-
-
Young, K.J.1
Bennett, J.P.2
-
79
-
-
77956553917
-
Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer’s disease
-
PID: 2047
-
Massaad CA, Amin SK, Hu L, Mei Y, Klann E, Pautler RG (2010) Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer’s disease. PLoS One 5(5):e10561. doi:10.1371/journal.pone.0010561
-
(2010)
PLoS One
, vol.5
, Issue.5
, pp. 10561
-
-
Massaad, C.A.1
Amin, S.K.2
Hu, L.3
Mei, Y.4
Klann, E.5
Pautler, R.G.6
-
80
-
-
84873130522
-
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer’s neurons
-
COI: 1:CAS:528:DC%2BC3sXis1ymsbo%3D, PID: 2338
-
Guo L, Du H, Yan S, Wu X, McKhann GM, Chen JX, Yan SS (2013) Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer’s neurons. PLoS One 8(1):e54914. doi:10.1371/journal.pone.0054914
-
(2013)
PLoS One
, vol.8
, Issue.1
, pp. 54914
-
-
Guo, L.1
Du, H.2
Yan, S.3
Wu, X.4
McKhann, G.M.5
Chen, J.X.6
Yan, S.S.7
-
81
-
-
9444226972
-
Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit
-
COI: 1:CAS:528:DC%2BD2cXhtVaqtbzK, PID: 1554
-
Yi M, Weaver D, Hajnoczky G (2004) Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit. J Cell Biol 167(4):661–672. doi:10.1083/jcb.200406038
-
(2004)
J Cell Biol
, vol.167
, Issue.4
, pp. 661-672
-
-
Yi, M.1
Weaver, D.2
Hajnoczky, G.3
-
82
-
-
84890478683
-
Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway
-
COI: 1:CAS:528:DC%2BC3sXhvVOn
-
Roh SE, Woo JA, Lakshmana MK, Uhlar C, Ankala V, Boggess T, Liu T, Hong YH, Mook-Jung I, Kim SJ, Kang DE (2013) Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway. FASEB J Off Publ Fed Am Soc Exp Biol 27(12):4776–4789. doi:10.1096/fj.13-234765
-
(2013)
FASEB J Off Publ Fed Am Soc Exp Biol
, vol.27
, Issue.12
, pp. 4776-4789
-
-
Roh, S.E.1
Woo, J.A.2
Lakshmana, M.K.3
Uhlar, C.4
Ankala, V.5
Boggess, T.6
Liu, T.7
Hong, Y.H.8
Mook-Jung, I.9
Kim, S.J.10
Kang, D.E.11
-
83
-
-
77949801029
-
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
-
COI: 1:CAS:528:DC%2BC3cXlvVagur
-
Misko A, Jiang S, Wegorzewska I, Milbrandt J, Baloh RH (2010) Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J Neurosci Off J Soc Neurosci 30(12):4232–4240. doi:10.1523/JNEUROSCI.6248-09.2010
-
(2010)
J Neurosci Off J Soc Neurosci
, vol.30
, Issue.12
, pp. 4232-4240
-
-
Misko, A.1
Jiang, S.2
Wegorzewska, I.3
Milbrandt, J.4
Baloh, R.H.5
-
84
-
-
84899895001
-
Oxidative stress in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXmvFCnsLo%3D, PID: 2466
-
Chen Z, Zhong C (2014) Oxidative stress in Alzheimer’s disease. Neurosci Bull 30(2):271–281. doi:10.1007/s12264-013-1423-y
-
(2014)
Neurosci Bull
, vol.30
, Issue.2
, pp. 271-281
-
-
Chen, Z.1
Zhong, C.2
-
85
-
-
84903215603
-
March separate, strike together—role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer’s disease
-
Eckert A, Nisbet R, Grimm A, Gotz J (2013) March separate, strike together—role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer’s disease. Biochim Biophys Acta. doi:10.1016/j.bbadis.2013.08.013
-
(2013)
Biochim Biophys Acta
-
-
Eckert, A.1
Nisbet, R.2
Grimm, A.3
Gotz, J.4
-
86
-
-
38349046973
-
Autophagy, amyloidogenesis and Alzheimer disease
-
COI: 1:CAS:528:DC%2BD1cXmtFeisg%3D%3D, PID: 1803
-
Nixon RA (2007) Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 120(Pt 23):4081–4091. doi:10.1242/jcs.019265
-
(2007)
J Cell Sci
, vol.120
, pp. 4081-4091
-
-
Nixon, R.A.1
-
87
-
-
84904678185
-
Apolipoprotein E in Alzheimer’s disease: an update
-
COI: 1:CAS:528:DC%2BC2cXhsVKgt7fP, PID: 2482
-
Yu JT, Tan L, Hardy J (2014) Apolipoprotein E in Alzheimer’s disease: an update. Annu Rev Neurosci 37:79–100. doi:10.1146/annurev-neuro-071013-014300
-
(2014)
Annu Rev Neurosci
, vol.37
, pp. 79-100
-
-
Yu, J.T.1
Tan, L.2
Hardy, J.3
-
88
-
-
84939895008
-
The role of SORL1 in Alzheimer’s disease
-
Yin RH, Yu JT, Tan L (2014) The role of SORL1 in Alzheimer’s disease. Mol Neurobiol. doi:10.1007/s12035-014-8742-5
-
(2014)
Mol Neurobiol
-
-
Yin, R.H.1
Yu, J.T.2
Tan, L.3
-
89
-
-
77952549902
-
Abeta exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3cXlsFShtr4%3D, PID: 1978
-
Folwell J, Cowan CM, Ubhi KK, Shiabh H, Newman TA, Shepherd D, Mudher A (2010) Abeta exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer’s disease. Exp Neurol 223(2):401–409. doi:10.1016/j.expneurol.2009.09.014
-
(2010)
Exp Neurol
, vol.223
, Issue.2
, pp. 401-409
-
-
Folwell, J.1
Cowan, C.M.2
Ubhi, K.K.3
Shiabh, H.4
Newman, T.A.5
Shepherd, D.6
Mudher, A.7
-
90
-
-
77957737750
-
Tau reduction prevents Abeta-induced defects in axonal transport
-
COI: 1:CAS:528:DC%2BC3cXht1CgtrfN, PID: 2082
-
Vossel KA, Zhang K, Brodbeck J, Daub AC, Sharma P, Finkbeiner S, Cui B, Mucke L (2010) Tau reduction prevents Abeta-induced defects in axonal transport. Science 330(6001):198. doi:10.1126/science.1194653
-
(2010)
Science
, vol.330
, Issue.6001
, pp. 198
-
-
Vossel, K.A.1
Zhang, K.2
Brodbeck, J.3
Daub, A.C.4
Sharma, P.5
Finkbeiner, S.6
Cui, B.7
Mucke, L.8
-
91
-
-
77953808475
-
Loss of tau elicits axonal degeneration in a mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3cXnvVOmsb8%3D, PID: 2043
-
Dawson HN, Cantillana V, Jansen M, Wang H, Vitek MP, Wilcock DM, Lynch JR, Laskowitz DT (2010) Loss of tau elicits axonal degeneration in a mouse model of Alzheimer’s disease. Neuroscience 169(1):516–531. doi:10.1016/j.neuroscience.2010.04.037
-
(2010)
Neuroscience
, vol.169
, Issue.1
, pp. 516-531
-
-
Dawson, H.N.1
Cantillana, V.2
Jansen, M.3
Wang, H.4
Vitek, M.P.5
Wilcock, D.M.6
Lynch, J.R.7
Laskowitz, D.T.8
-
92
-
-
84886752586
-
Presenilin controls kinesin-1 and dynein function during APP-vesicle transport invivo
-
COI: 1:CAS:528:DC%2BC3sXhvVGqu7zI, PID: 2371
-
Gunawardena S, Yang G, Goldstein LS (2013) Presenilin controls kinesin-1 and dynein function during APP-vesicle transport invivo. Hum Mol Genet 22(19):3828–3843. doi:10.1093/hmg/ddt237
-
(2013)
Hum Mol Genet
, vol.22
, Issue.19
, pp. 3828-3843
-
-
Gunawardena, S.1
Yang, G.2
Goldstein, L.S.3
-
93
-
-
84866150232
-
Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer’s disease-related tau phosphorylation via PAR-1
-
COI: 1:CAS:528:DC%2BC38XhtlSjsrrM, PID: 2295
-
Iijima-Ando K, Sekiya M, Maruko-Otake A, Ohtake Y, Suzuki E, Lu B, Iijima KM (2012) Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer’s disease-related tau phosphorylation via PAR-1. PLoS Genet 8(8):e1002918. doi:10.1371/journal.pgen.1002918
-
(2012)
PLoS Genet
, vol.8
, Issue.8
, pp. 1002918
-
-
Iijima-Ando, K.1
Sekiya, M.2
Maruko-Otake, A.3
Ohtake, Y.4
Suzuki, E.5
Lu, B.6
Iijima, K.M.7
-
94
-
-
77958459087
-
Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies
-
COI: 1:CAS:528:DC%2BC3cXhtlaktrvJ, PID: 2081
-
Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS (2010) Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet 19(22):4399–4408. doi:10.1093/hmg/ddq363
-
(2010)
Hum Mol Genet
, vol.19
, Issue.22
, pp. 4399-4408
-
-
Falzone, T.L.1
Gunawardena, S.2
McCleary, D.3
Reis, G.F.4
Goldstein, L.S.5
-
95
-
-
84864395349
-
Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies
-
COI: 1:CAS:528:DC%2BC38XhtVOjtrnJ, PID: 2281
-
Brunden KR, Ballatore C, Lee VM, Smith AB 3rd, Trojanowski JQ (2012) Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies. Biochem Soc Trans 40(4):661–666. doi:10.1042/BST20120010
-
(2012)
Biochem Soc Trans
, vol.40
, Issue.4
, pp. 661-666
-
-
Brunden, K.R.1
Ballatore, C.2
Lee, V.M.3
Smith, A.B.4
Trojanowski, J.Q.5
-
96
-
-
84879412186
-
NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy
-
COI: 1:CAS:528:DC%2BC3sXhtVSiu7rN, PID: 2358
-
Quraishe S, Cowan CM, Mudher A (2013) NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy. Mol Psychiatry 18(7):834–842. doi:10.1038/mp.2013.32
-
(2013)
Mol Psychiatry
, vol.18
, Issue.7
, pp. 834-842
-
-
Quraishe, S.1
Cowan, C.M.2
Mudher, A.3
-
97
-
-
84887848354
-
Notch signalling in adult neurons: a potential target for microtubule stabilization
-
COI: 1:CAS:528:DC%2BC2cXhs1OgtL3K, PID: 2422
-
Bonini SA, Ferrari-Toninelli G, Montinaro M, Memo M (2013) Notch signalling in adult neurons: a potential target for microtubule stabilization. Ther Adv Neurol Disord 6(6):375–385. doi:10.1177/1756285613490051
-
(2013)
Ther Adv Neurol Disord
, vol.6
, Issue.6
, pp. 375-385
-
-
Bonini, S.A.1
Ferrari-Toninelli, G.2
Montinaro, M.3
Memo, M.4
-
98
-
-
84890676730
-
Proteasome inhibition induces stress kinase dependent transport deficits—implications for Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXitleqtr4%3D, PID: 2427
-
Agholme L, Nath S, Domert J, Marcusson J, Kagedal K, Hallbeck M (2014) Proteasome inhibition induces stress kinase dependent transport deficits—implications for Alzheimer’s disease. Mol Cell Neurosci 58:29–39. doi:10.1016/j.mcn.2013.11.001
-
(2014)
Mol Cell Neurosci
, vol.58
, pp. 29-39
-
-
Agholme, L.1
Nath, S.2
Domert, J.3
Marcusson, J.4
Kagedal, K.5
Hallbeck, M.6
-
99
-
-
84884680215
-
Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3beta signaling
-
COI: 1:CAS:528:DC%2BC3sXhsFKitb3P, PID: 2408
-
Shaw JL, Chang KT (2013) Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3beta signaling. PLoS Genet 9(9):e1003792. doi:10.1371/journal.pgen.1003792
-
(2013)
PLoS Genet
, vol.9
, Issue.9
, pp. 1003792
-
-
Shaw, J.L.1
Chang, K.T.2
-
100
-
-
84939885240
-
The role of cholesterol metabolism in Alzheimer’s disease
-
Sun JH, Yu JT, Tan L (2014) The role of cholesterol metabolism in Alzheimer’s disease. Mol Neurobiol. doi:10.1007/s12035-014-8749-y
-
(2014)
Mol Neurobiol
-
-
Sun, J.H.1
Yu, J.T.2
Tan, L.3
|