-
1
-
-
70350455072
-
Axonal transport defects in neurodegenerative diseases
-
Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, et al. (2009) Axonal transport defects in neurodegenerative diseases. J Neurosci 29: 12776-12786.
-
(2009)
J Neurosci
, vol.29
, pp. 12776-12786
-
-
Morfini, G.A.1
Burns, M.2
Binder, L.I.3
Kanaan, N.M.4
LaPointe, N.5
-
2
-
-
67649826155
-
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
-
Morfini GA, You YM, Pollema SL, Kaminska A, Liu K, et al. (2009) Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nat Neurosci 12: 864-871.
-
(2009)
Nat Neurosci
, vol.12
, pp. 864-871
-
-
Morfini, G.A.1
You, Y.M.2
Pollema, S.L.3
Kaminska, A.4
Liu, K.5
-
3
-
-
79958234539
-
Peripheral neuropathies: Molecular diagnosis of Charcot-Marie-Tooth disease
-
Berciano J, (2011) Peripheral neuropathies: Molecular diagnosis of Charcot-Marie-Tooth disease. Nat Rev Neurol 7: 305-306.
-
(2011)
Nat Rev Neurol
, vol.7
, pp. 305-306
-
-
Berciano, J.1
-
4
-
-
0141864562
-
Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms
-
Hiruma H, Katakura T, Takahashi S, Ichikawa T, Kawakami T, (2003) Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms. J Neurosci 23: 8967-8977.
-
(2003)
J Neurosci
, vol.23
, pp. 8967-8977
-
-
Hiruma, H.1
Katakura, T.2
Takahashi, S.3
Ichikawa, T.4
Kawakami, T.5
-
5
-
-
65249161745
-
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta
-
Pigino G, Morfini G, Atagi Y, Deshpande A, Yu C, et al. (2009) Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta. Proc Natl Acad Sci U S A 106: 5907-5912.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5907-5912
-
-
Pigino, G.1
Morfini, G.2
Atagi, Y.3
Deshpande, A.4
Yu, C.5
-
6
-
-
69949102785
-
Examination of potential mechanisms of amyloid-induced defects in neuronal transport
-
Shah SB, Nolan R, Davis E, Stokin GB, Niesman I, et al. (2009) Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis 36: 11-25.
-
(2009)
Neurobiol Dis
, vol.36
, pp. 11-25
-
-
Shah, S.B.1
Nolan, R.2
Davis, E.3
Stokin, G.B.4
Niesman, I.5
-
7
-
-
77954466407
-
Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons
-
Decker H, Lo KY, Unger SM, Ferreira ST, Silverman MA, (2010) Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons. J Neurosci 30: 9166-9171.
-
(2010)
J Neurosci
, vol.30
, pp. 9166-9171
-
-
Decker, H.1
Lo, K.Y.2
Unger, S.M.3
Ferreira, S.T.4
Silverman, M.A.5
-
8
-
-
77957737750
-
Tau reduction prevents Abeta-induced defects in axonal transport
-
Vossel KA, Zhang K, Brodbeck J, Daub AC, Sharma P, et al. (2010) Tau reduction prevents Abeta-induced defects in axonal transport. Science 330: 198.
-
(2010)
Science
, vol.330
, pp. 198
-
-
Vossel, K.A.1
Zhang, K.2
Brodbeck, J.3
Daub, A.C.4
Sharma, P.5
-
9
-
-
79954586115
-
CK1 activates minus-end-directed transport of membrane organelles along microtubules
-
Ikeda K, Zhapparova O, Brodsky I, Semenova I, Tirnauer JS, et al. (2011) CK1 activates minus-end-directed transport of membrane organelles along microtubules. Mol Biol Cell 22: 1321-1329.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1321-1329
-
-
Ikeda, K.1
Zhapparova, O.2
Brodsky, I.3
Semenova, I.4
Tirnauer, J.S.5
-
10
-
-
44049089139
-
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling
-
Magdesian MH, Carvalho MM, Mendes FA, Saraiva LM, Juliano MA, et al. (2008) Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling. J Biol Chem 283: 9359-9368.
-
(2008)
J Biol Chem
, vol.283
, pp. 9359-9368
-
-
Magdesian, M.H.1
Carvalho, M.M.2
Mendes, F.A.3
Saraiva, L.M.4
Juliano, M.A.5
-
11
-
-
36348935683
-
Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway
-
Townsend M, Mehta T, Selkoe DJ, (2007) Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem 282: 33305-33312.
-
(2007)
J Biol Chem
, vol.282
, pp. 33305-33312
-
-
Townsend, M.1
Mehta, T.2
Selkoe, D.J.3
-
12
-
-
0037975676
-
Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta
-
Hoshi M, Sato M, Matsumoto S, Noguchi A, Yasutake K, et al. (2003) Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta. Proc Natl Acad Sci U S A 100: 6370-6375.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 6370-6375
-
-
Hoshi, M.1
Sato, M.2
Matsumoto, S.3
Noguchi, A.4
Yasutake, K.5
-
13
-
-
47049120422
-
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers
-
De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, et al. (2008) Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers. Neurobiol Aging 29: 1334-1347.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1334-1347
-
-
de Felice, F.G.1
Wu, D.2
Lambert, M.P.3
Fernandez, S.J.4
Velasco, P.T.5
-
14
-
-
0036469290
-
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
-
Morfini G, Szebenyi G, Elluru R, Ratner N, Brady ST, (2002) Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J 21: 281-293.
-
(2002)
EMBO J
, vol.21
, pp. 281-293
-
-
Morfini, G.1
Szebenyi, G.2
Elluru, R.3
Ratner, N.4
Brady, S.T.5
-
15
-
-
51349143580
-
Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin
-
Cuchillo-Ibanez I, Seereeram A, Byers HL, Leung KY, Ward MA, et al. (2008) Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin. FASEB J 22: 3186-3195.
-
(2008)
FASEB J
, vol.22
, pp. 3186-3195
-
-
Cuchillo-Ibanez, I.1
Seereeram, A.2
Byers, H.L.3
Leung, K.Y.4
Ward, M.A.5
-
16
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
-
Ebneth A, Godemann R, Stamer K, Illenberger S, Trinczek B, et al. (1998) Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J Cell Biol 143: 777-794.
-
(1998)
J Cell Biol
, vol.143
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
-
17
-
-
5444273804
-
MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
-
Mandelkow EM, Thies E, Trinczek B, Biernat J, Mandelkow E, (2004) MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons. J Cell Biol 167: 99-110.
-
(2004)
J Cell Biol
, vol.167
, pp. 99-110
-
-
Mandelkow, E.M.1
Thies, E.2
Trinczek, B.3
Biernat, J.4
Mandelkow, E.5
-
18
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
Lucas JJ, Hernandez F, Gomez-Ramos P, Moran MA, Hen R, et al. (2001) Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 20: 27-39.
-
(2001)
EMBO J
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernandez, F.2
Gomez-Ramos, P.3
Moran, M.A.4
Hen, R.5
-
19
-
-
0029152786
-
Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos
-
Dominguez I, Itoh K, Sokol SY, (1995) Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos. Proc Natl Acad Sci U S A 92: 8498-8502.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8498-8502
-
-
Dominguez, I.1
Itoh, K.2
Sokol, S.Y.3
-
20
-
-
34147192803
-
Visualization and quantification of mitochondrial dynamics in living animal cells
-
De Vos KJ, Sheetz MP, (2007) Visualization and quantification of mitochondrial dynamics in living animal cells. Methods Cell Biol 80: 627-682.
-
(2007)
Methods Cell Biol
, vol.80
, pp. 627-682
-
-
de Vos, K.J.1
Sheetz, M.P.2
-
21
-
-
0028820411
-
Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules
-
Trinczek B, Biernat J, Baumann K, Mandelkow EM, Mandelkow E, (1995) Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules. Mol Biol Cell 6: 1887-1902.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 1887-1902
-
-
Trinczek, B.1
Biernat, J.2
Baumann, K.3
Mandelkow, E.M.4
Mandelkow, E.5
-
22
-
-
35948978460
-
Moving mitochondria: establishing distribution of an essential organelle
-
Frederick RL, Shaw JM, (2007) Moving mitochondria: establishing distribution of an essential organelle. Traffic 8: 1668-1675.
-
(2007)
Traffic
, vol.8
, pp. 1668-1675
-
-
Frederick, R.L.1
Shaw, J.M.2
-
23
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
Dixit R, Ross JL, Goldman YE, Holzbaur EL, (2008) Differential regulation of dynein and kinesin motor proteins by tau. Science 319: 1086-1089.
-
(2008)
Science
, vol.319
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.4
-
24
-
-
33745567523
-
Role of MAP1B in axonal retrograde transport of mitochondria
-
Jimenez-Mateos EM, Gonzalez-Billault C, Dawson HN, Vitek MP, Avila J, (2006) Role of MAP1B in axonal retrograde transport of mitochondria. Biochem J 397: 53-59.
-
(2006)
Biochem J
, vol.397
, pp. 53-59
-
-
Jimenez-Mateos, E.M.1
Gonzalez-Billault, C.2
Dawson, H.N.3
Vitek, M.P.4
Avila, J.5
-
25
-
-
0030908590
-
Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly
-
Utton MA, Vandecandelaere A, Wagner U, Reynolds CH, Gibb GM, et al. (1997) Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly. Biochem J 323 (Pt 3): 741-747.
-
(1997)
Biochem J
, vol.323
, Issue.Pt 3
, pp. 741-747
-
-
Utton, M.A.1
Vandecandelaere, A.2
Wagner, U.3
Reynolds, C.H.4
Gibb, G.M.5
-
26
-
-
39549117998
-
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
-
Yuan A, Kumar A, Peterhoff C, Duff K, Nixon RA, (2008) Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. J Neurosci 28: 1682-1687.
-
(2008)
J Neurosci
, vol.28
, pp. 1682-1687
-
-
Yuan, A.1
Kumar, A.2
Peterhoff, C.3
Duff, K.4
Nixon, R.A.5
-
27
-
-
0028861992
-
Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons
-
Morris RL, Hollenbeck PJ, (1995) Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J Cell Biol 131: 1315-1326.
-
(1995)
J Cell Biol
, vol.131
, pp. 1315-1326
-
-
Morris, R.L.1
Hollenbeck, P.J.2
-
28
-
-
0019867311
-
Dependence of fast axonal transport on the local concentration of organelles
-
Mackey S, Schuessler G, Goldberg DJ, Schwartz JH, (1981) Dependence of fast axonal transport on the local concentration of organelles. Biophys J 36: 455-459.
-
(1981)
Biophys J
, vol.36
, pp. 455-459
-
-
Mackey, S.1
Schuessler, G.2
Goldberg, D.J.3
Schwartz, J.H.4
-
29
-
-
30544452263
-
The axonal transport of mitochondria
-
Hollenbeck PJ, Saxton WM, (2005) The axonal transport of mitochondria. J Cell Sci 118: 5411-5419.
-
(2005)
J Cell Sci
, vol.118
, pp. 5411-5419
-
-
Hollenbeck, P.J.1
Saxton, W.M.2
-
30
-
-
33845927357
-
Mitochondrial trafficking and morphology in healthy and injured neurons
-
Chang DT, Reynolds IJ, (2006) Mitochondrial trafficking and morphology in healthy and injured neurons. Prog Neurobiol 80: 241-268.
-
(2006)
Prog Neurobiol
, vol.80
, pp. 241-268
-
-
Chang, D.T.1
Reynolds, I.J.2
-
31
-
-
33745601933
-
The relationship between mitochondrial shape and function and the cytoskeleton
-
Anesti V, Scorrano L, (2006) The relationship between mitochondrial shape and function and the cytoskeleton. Biochim Biophys Acta 1757: 692-699.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 692-699
-
-
Anesti, V.1
Scorrano, L.2
-
32
-
-
79151485570
-
Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses
-
MacAskill AF, Atkin TA, Kittler JT, (2010) Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses. Eur J Neurosci 32: 231-240.
-
(2010)
Eur J Neurosci
, vol.32
, pp. 231-240
-
-
MacAskill, A.F.1
Atkin, T.A.2
Kittler, J.T.3
-
33
-
-
75149115122
-
Control of mitochondrial transport and localization in neurons
-
MacAskill AF, Kittler JT, (2010) Control of mitochondrial transport and localization in neurons. Trends Cell Biol 20: 102-112.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 102-112
-
-
MacAskill, A.F.1
Kittler, J.T.2
-
34
-
-
77952548853
-
Glycogen synthase kinase-3beta and the p25 activator of cyclin dependent kinase 5 increase pausing of mitochondria in neurons
-
Morel M, Authelet M, Dedecker R, Brion JP, (2010) Glycogen synthase kinase-3beta and the p25 activator of cyclin dependent kinase 5 increase pausing of mitochondria in neurons. Neuroscience 167: 1044-1056.
-
(2010)
Neuroscience
, vol.167
, pp. 1044-1056
-
-
Morel, M.1
Authelet, M.2
Dedecker, R.3
Brion, J.P.4
-
35
-
-
0037119947
-
Single-molecule investigation of the interference between kinesin, tau and MAP2c
-
Seitz A, Kojima H, Oiwa K, Mandelkow EM, Song YH, et al. (2002) Single-molecule investigation of the interference between kinesin, tau and MAP2c. EMBO J 21: 4896-4905.
-
(2002)
EMBO J
, vol.21
, pp. 4896-4905
-
-
Seitz, A.1
Kojima, H.2
Oiwa, K.3
Mandelkow, E.M.4
Song, Y.H.5
-
36
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow EM, Stamer K, Vogel R, Thies E, Mandelkow E, (2003) Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 24: 1079-1085.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 1079-1085
-
-
Mandelkow, E.M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
37
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow EM, (2002) Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol 156: 1051-1063.
-
(2002)
J Cell Biol
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.M.5
-
38
-
-
34250019938
-
Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice
-
Gomez-Sintes R, Hernandez F, Bortolozzi A, Artigas F, Avila J, et al. (2007) Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice. EMBO J 26: 2743-2754.
-
(2007)
EMBO J
, vol.26
, pp. 2743-2754
-
-
Gomez-Sintes, R.1
Hernandez, F.2
Bortolozzi, A.3
Artigas, F.4
Avila, J.5
-
39
-
-
84858796216
-
Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress
-
Zhang LF, Shi L, Liu H, Meng FT, Liu YJ, et al. (2011) Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. Int J Neuropsychopharmacol pp. 1-12.
-
(2011)
Int J Neuropsychopharmacol
, pp. 1-12
-
-
Zhang, L.F.1
Shi, L.2
Liu, H.3
Meng, F.T.4
Liu, Y.J.5
-
40
-
-
81055138730
-
Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
-
Kanaan NM, Morfini G, Pigino G, Lapointe NE, Andreadis A, et al. (2011) Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport. Neurobiol Aging.
-
(2011)
Neurobiol Aging
-
-
Kanaan, N.M.1
Morfini, G.2
Pigino, G.3
Lapointe, N.E.4
Andreadis, A.5
-
41
-
-
0029835019
-
A spatial gradient of tau protein phosphorylation in nascent axons
-
Mandell JW, Banker GA, (1996) A spatial gradient of tau protein phosphorylation in nascent axons. J Neurosci 16: 5727-5740.
-
(1996)
J Neurosci
, vol.16
, pp. 5727-5740
-
-
Mandell, J.W.1
Banker, G.A.2
-
42
-
-
33846118789
-
Multiple-motor based transport and its regulation by Tau
-
Vershinin M, Carter BC, Razafsky DS, King SJ, Gross SP, (2007) Multiple-motor based transport and its regulation by Tau. Proc Natl Acad Sci U S A 104: 87-92.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 87-92
-
-
Vershinin, M.1
Carter, B.C.2
Razafsky, D.S.3
King, S.J.4
Gross, S.P.5
-
43
-
-
79960032374
-
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases
-
Kanaan NM, Morfini GA, LaPointe NE, Pigino GF, Patterson KR, et al. (2011) Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases. J Neurosci 31: 9858-9868.
-
(2011)
J Neurosci
, vol.31
, pp. 9858-9868
-
-
Kanaan, N.M.1
Morfini, G.A.2
LaPointe, N.E.3
Pigino, G.F.4
Patterson, K.R.5
-
44
-
-
0028175823
-
Role of phosphorylated MAPlB in neuritogenesis
-
Avila J, Ulloa L, Diez-Guerra J, Diaz-Nido J, (1994) Role of phosphorylated MAPlB in neuritogenesis. Cell Biol Int 18: 309-314.
-
(1994)
Cell Biol Int
, vol.18
, pp. 309-314
-
-
Avila, J.1
Ulloa, L.2
Diez-Guerra, J.3
Diaz-Nido, J.4
-
45
-
-
0023729788
-
A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation
-
Diaz-Nido J, Serrano L, Mendez E, Avila J, (1988) A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation. J Cell Biol 106: 2057-2065.
-
(1988)
J Cell Biol
, vol.106
, pp. 2057-2065
-
-
Diaz-Nido, J.1
Serrano, L.2
Mendez, E.3
Avila, J.4
-
46
-
-
0027538331
-
Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells
-
Ulloa L, Diaz-Nido J, Avila J, (1993) Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells. EMBO J 12: 1633-1640.
-
(1993)
EMBO J
, vol.12
, pp. 1633-1640
-
-
Ulloa, L.1
Diaz-Nido, J.2
Avila, J.3
|