-
1
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
2-s2.0-77951540816 10.1038/nature08890
-
de Calignon A., Fox L. M., Pitstick R., Carlson G. A., Bacskai B. J., Spires-Jones T. L., Hyman B. T., Caspase activation precedes and leads to tangles. Nature 2010 464 7292 1201 1204 2-s2.0-77951540816 10.1038/nature08890
-
(2010)
Nature
, vol.464
, Issue.7292
, pp. 1201-1204
-
-
De Calignon, A.1
Fox, L.M.2
Pitstick, R.3
Carlson, G.A.4
Bacskai, B.J.5
Spires-Jones, T.L.6
Hyman, B.T.7
-
2
-
-
0027398169
-
Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament
-
Novak M., Kabat J., Wischik C. M., Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament. The EMBO Journal 1993 12 1 365 370 2-s2.0-0027398169 (Pubitemid 23042416)
-
(1993)
EMBO Journal
, vol.12
, Issue.1
, pp. 365-370
-
-
Novak, M.1
Kabat, J.2
Wischik, C.M.3
-
3
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
DOI 10.1073/pnas.1630428100
-
Gamblin T. C., Chen F., Zambrano A., Abraha A., Lagalwar S., Guillozet A. L., Lu M., Fu Y., Garcia-Sierra F., LaPointe N., Miller R., Berry R. W., Binder L. I., Cryns V. L., Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America 2003 100 17 10032 10037 2-s2.0-0041689948 10.1073/pnas.1630428100 (Pubitemid 37087063)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
4
-
-
3242749074
-
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
-
DOI 10.1172/JCI200420640
-
Rissman R. A., Poon W. W., Blurton-Jones M., Oddo S., Torp R., Vitek M. P., LaFerla F. M., Rohn T. T., Cotman C. W., Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. Journal of Clinical Investigation 2004 114 1 121 130 2-s2.0-3242749074 10.1172/JCI200420640 (Pubitemid 39071651)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.1
, pp. 121-130
-
-
Rissman, R.A.1
Poon, W.W.2
Blurton-Jones, M.3
Oddo, S.4
Torp, R.5
Vitek, M.P.6
LaFerla, F.M.7
Rohn, T.T.8
Cotman, C.W.9
-
5
-
-
33745827715
-
Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation
-
DOI 10.1074/jbc.M511697200
-
Ding H., Matthews T. A., Johnson G. V. W., Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation. Journal of Biological Chemistry 2006 281 28 19107 19114 2-s2.0-33745827715 10.1074/jbc.M511697200 (Pubitemid 44035415)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.28
, pp. 19107-19114
-
-
Ding, H.1
Matthews, T.A.2
Johnson, G.V.W.3
-
6
-
-
33947495186
-
Post-translational modifications of tau protein
-
2-s2.0-33947495186
-
Pevalova M., Filipcik P., Novak M., Avila J., Iqbal K., Post-translational modifications of tau protein. Bratislavské Lekárske Listy 2006 107 9-10 346 353 2-s2.0-33947495186
-
(2006)
Bratislavské Lekárske Listy
, vol.107
, Issue.9-10
, pp. 346-353
-
-
Pevalova, M.1
Filipcik, P.2
Novak, M.3
Avila, J.4
Iqbal, K.5
-
7
-
-
38749144389
-
Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy
-
DOI 10.2353/ajpath.2008.070627
-
Delobel P., Lavenir I., Fraser G., Ingram E., Holzer M., Ghetti B., Spillantini M. G., Crowther R. A., Goedert M., Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. American Journal of Pathology 2008 172 1 123 131 2-s2.0-38749144389 10.2353/ajpath.2008.070627 (Pubitemid 351186374)
-
(2008)
American Journal of Pathology
, vol.172
, Issue.1
, pp. 123-131
-
-
Delobel, P.1
Lavenir, I.2
Fraser, G.3
Ingram, E.4
Holzer, M.5
Ghetti, B.6
Spillantini, M.G.7
Crowther, R.A.8
Goedert, M.9
-
8
-
-
62649093953
-
Role of caspase-3 in tau truncation at D421 is restricted in transgenic mouse models for tauopathies
-
2-s2.0-62649093953 10.1111/j.1471-4159.2009.05959.x
-
Zhang Q., Zhang X., Chen J., Miao Y., Sun A., Role of caspase-3 in tau truncation at D421 is restricted in transgenic mouse models for tauopathies. Journal of Neurochemistry 2009 109 2 476 484 2-s2.0-62649093953 10.1111/j.1471-4159.2009.05959.x
-
(2009)
Journal of Neurochemistry
, vol.109
, Issue.2
, pp. 476-484
-
-
Zhang, Q.1
Zhang, X.2
Chen, J.3
Miao, Y.4
Sun, A.5
-
9
-
-
43249129441
-
391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease
-
DOI 10.1097/NEN.0b013e31817275c7
-
Basurto-Islas G., Luna-Muñoz J., Guillozet-Bongaarts A. L., Binder L. I., Mena R., García-Sierra F., Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer's disease. Journal of Neuropathology and Experimental Neurology 2008 67 5 470 483 2-s2.0-43249129441 10.1097/NEN.0b013e31817275c7 (Pubitemid 351653539)
-
(2008)
Journal of Neuropathology and Experimental Neurology
, vol.67
, Issue.5
, pp. 470-483
-
-
Basurto-Islas, G.1
Luna-Munoz, J.2
Guillozet-Bongaarts, A.L.3
Binder, L.I.4
Mena, R.5
Garcia-Sierra, F.6
-
10
-
-
20044381844
-
Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2004.09.019
-
Guillozet-Bongaarts A. L., Garcia-Sierra F., Reynolds M. R., Horowitz P. M., Fu Y., Wang T., Cahill M. E., Bigio E. H., Berry R. W., Binder L. I., Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease. Neurobiology of Aging 2005 26 7 1015 1022 2-s2.0-20044381844 10.1016/j.neurobiolaging.2004.09.019 (Pubitemid 40312665)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.7
, pp. 1015-1022
-
-
Guillozet-Bongaarts, A.L.1
Garcia-Sierra, F.2
Reynolds, M.R.3
Horowitz, P.M.4
Fu, Y.5
Wang, T.6
Cahill, M.E.7
Bigio, E.H.8
Berry, R.W.9
Binder, L.I.10
-
11
-
-
34247604427
-
Phosphorylation and cleavage of tau in non-AD tauopathies
-
DOI 10.1007/s00401-007-0209-6
-
Guillozet-Bongaarts A. L., Glajch K. E., Libson E. G., Cahill M. E., Bigio E., Berry R. W., Binder L. I., Phosphorylation and cleavage of tau in non-AD tauopathies. Acta Neuropathologica 2007 113 5 513 520 2-s2.0-34247604427 10.1007/s00401-007-0209-6 (Pubitemid 46672597)
-
(2007)
Acta Neuropathologica
, vol.113
, Issue.5
, pp. 513-520
-
-
Guillozet-Bongaarts, A.L.1
Glajch, K.E.2
Libson, E.G.3
Cahill, M.E.4
Bigio, E.5
Berry, R.W.6
Binder, L.I.7
-
12
-
-
10944248857
-
Tau, tangles, and Alzheimer's disease
-
DOI 10.1016/j.bbadis.2004.08.014, PII S0925443904001619
-
Binder L. I., Guillozet-Bongaarts A. L., Garcia-Sierra F., Berry R. W., Tau, tangles, and Alzheimer's disease. Biochimica et Biophysica Acta 2005 1739 2 216 223 2-s2.0-10944248857 10.1016/j.bbadis.2004.08.014 (Pubitemid 40018540)
-
(2005)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.2
, pp. 216-223
-
-
Binder, L.I.1
Guillozet-Bongaarts, A.L.2
Garcia-Sierra, F.3
Berry, R.W.4
-
13
-
-
12644260802
-
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology
-
DOI 10.1074/jbc.271.51.32789
-
Carmel G., Mager E. M., Binder L. I., Kuret J., The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. Journal of Biological Chemistry 1996 271 51 32789 32795 2-s2.0-12644260802 10.1074/jbc.271.51.32789 (Pubitemid 27008707)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.51
, pp. 32789-32795
-
-
Carmel, G.1
Mager, E.M.2
Binder, L.I.3
Kuret, J.4
-
14
-
-
0035011587
-
Tau-66: Evidence for a novel tau conformation in alzheimer's disease
-
DOI 10.1046/j.1471-4159.2001.00346.x
-
Ghoshal N., García-Sierra F., Fu Y., Beckett L. A., Mufson E. J., Kuret J., Berry R. W., Binder L. I., Tau-66: evidence for a novel tau conformation in Alzheimer's disease. Journal of Neurochemistry 2001 77 5 1372 1385 2-s2.0-0035011587 10.1046/j.1471-4159.2001.00346.x (Pubitemid 32523690)
-
(2001)
Journal of Neurochemistry
, vol.77
, Issue.5
, pp. 1372-1385
-
-
Ghoshal, N.1
Garcia-Sierra, F.2
Fu, Y.3
Beckett, L.A.4
Mufson, E.J.5
Kuret, J.6
Berry, R.W.7
Binder, L.I.8
-
15
-
-
0037458021
-
Caspase 3 activation is essential for neuroprotection in preconditioning
-
DOI 10.1073/pnas.0232966100
-
McLaughlin B., Hartnett K. A., Erhardt J. A., Legos J. J., White R. F., Barone F. C., Aizenman E., Caspase 3 activation is essential for neuroprotection in preconditioning. Proceedings of the National Academy of Sciences of the United States of America 2003 100 2 715 720 2-s2.0-0037458021 10.1073/pnas.0232966100 (Pubitemid 36126118)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.2
, pp. 715-720
-
-
McLaughlin, B.1
Hartnett, K.A.2
Erhardt, J.A.3
Legos, J.J.4
White, R.F.5
Barone, F.C.6
Aizenman, E.7
-
16
-
-
68249138795
-
Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy
-
2-s2.0-68249138795 10.1097/NEN.0b013e3181a9fc66
-
de Calignon A., Spires-Jones T. L., Pitstick R., Carlson G. A., Hyman B. T., Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy. Journal of Neuropathology and Experimental Neurology 2009 68 7 757 761 2-s2.0-68249138795 10.1097/NEN.0b013e3181a9fc66
-
(2009)
Journal of Neuropathology and Experimental Neurology
, vol.68
, Issue.7
, pp. 757-761
-
-
De Calignon, A.1
Spires-Jones, T.L.2
Pitstick, R.3
Carlson, G.A.4
Hyman, B.T.5
-
18
-
-
80052163592
-
Immunoelectron microscopic and biochemical studies of caspase-cleaved tau in a mouse model of tauopathy
-
Lin W. L., Dickson D. W., Sahara N., Immunoelectron microscopic and biochemical studies of caspase-cleaved tau in a mouse model of tauopathy. Journal of Neuropathology and Experimental Neurology 2011 70 9 779 787
-
(2011)
Journal of Neuropathology and Experimental Neurology
, vol.70
, Issue.9
, pp. 779-787
-
-
Lin, W.L.1
Dickson, D.W.2
Sahara, N.3
-
19
-
-
4544248870
-
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease
-
DOI 10.1523/JNEUROSCI.1988-04.2004
-
Horowitz P. M., Patterson K. R., Guillozet-Bongaarts A. L., Reynolds M. R., Carroll C. A., Weintraub S. T., Bennett D. A., Cryns V. L., Berry R. W., Binder L. I., Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. Journal of Neuroscience 2004 24 36 7895 7902 2-s2.0-4544248870 10.1523/JNEUROSCI.1988-04.2004 (Pubitemid 39215694)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.36
, pp. 7895-7902
-
-
Horowitz, P.M.1
Patterson, K.R.2
Guillozet-Bongaarts, A.L.3
Reynolds, M.R.4
Carroll, C.A.5
Weintraub, S.T.6
Bennett, D.A.7
Cryns, V.L.8
Berry, R.W.9
Binder, L.I.10
-
20
-
-
3242811902
-
Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease
-
Guo H., Albrecht S., Bourdeau M., Petzke T., Bergeron C., LeBlanc A. C., Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease. American Journal of Pathology 2004 165 2 523 531 2-s2.0-3242811902 (Pubitemid 38971382)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.2
, pp. 523-531
-
-
Guo, H.1
Albrecht, S.2
Bourdeau, M.3
Petzke, T.4
Bergeron, C.5
LeBlanc, A.C.6
-
21
-
-
77955972018
-
Proteolytic processing of tau
-
2-s2.0-77955972018 10.1042/BST0380955
-
Wang Y., Garg S., Mandelkow E. M., Mandelkow E., Proteolytic processing of tau. Biochemical Society Transactions 2010 38 4 955 961 2-s2.0-77955972018 10.1042/BST0380955
-
(2010)
Biochemical Society Transactions
, vol.38
, Issue.4
, pp. 955-961
-
-
Wang, Y.1
Garg, S.2
Mandelkow, E.M.3
Mandelkow, E.4
-
22
-
-
80052795886
-
Potentiation of tau aggregation by cdk5 and GSK3beta
-
Lee S., Hall G. F., Shea T. B., Potentiation of tau aggregation by cdk5 and GSK3beta. Journal of Alzheimer's Disease 2011 26 2 355 364
-
(2011)
Journal of Alzheimer's Disease
, vol.26
, Issue.2
, pp. 355-364
-
-
Lee, S.1
Hall, G.F.2
Shea, T.B.3
-
23
-
-
33845974450
-
Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity
-
DOI 10.1074/jbc.M604863200
-
Iliev A. I., Ganesan S., Bunt G., Wouters F. S., Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity. Journal of Biological Chemistry 2006 281 48 37195 37204 2-s2.0-33845974450 10.1074/jbc.M604863200 (Pubitemid 46042189)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 37195-37204
-
-
Iliev, A.I.1
Ganesan, S.2
Bunt, G.3
Wouters, F.S.4
-
24
-
-
0035821647
-
Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms
-
DOI 10.1038/sj.onc.1204436
-
Belmokhtar C. A., Híllion J., Segal-Bendirdjian E., Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene 2001 20 26 3354 3362 2-s2.0-0035821647 10.1038/sj.onc. 1204436 (Pubitemid 32588984)
-
(2001)
Oncogene
, vol.20
, Issue.26
, pp. 3354-3362
-
-
Belmokhtar, C.A.1
Hillion, J.2
Segal-Bendirdjian, E.3
-
25
-
-
0029995766
-
A license to kill
-
DOI 10.1016/S0092-8674(00)81005-3
-
Fraser A., Evan G., A license to kill. Cell 1996 85 6 781 784 2-s2.0-0029995766 10.1016/S0092-8674(00)81005-3 (Pubitemid 26192130)
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 781-784
-
-
Fraser, A.1
Evan, G.2
-
26
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
2-s2.0-0029068871
-
Nicholson D. W., Ali A., Thornberry N. A., Vaillancourt J. P., Ding C. K., Gallant M., Gareau Y., Griffin P. R., Labelle M., Lazebnik Y. A., Munday N. A., Raju S. M., Smulson M. E., Yamin T. T., Yu V. L., Miller D. K., Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995 376 6535 37 43 2-s2.0-0029068871
-
(1995)
Nature
, vol.376
, Issue.6535
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
Munday, N.A.11
Raju, S.M.12
Smulson, M.E.13
Yamin, T.T.14
Yu, V.L.15
Miller, D.K.16
-
27
-
-
0024109687
-
Epitopes that span the tau molecule are shared with paired helical filaments
-
2-s2.0-0024109687
-
Kosik K. S., Orecchio L. D., Binder L., Trojanowski J. Q., Lee V. M. Y., Lee G., Epitopes that span the tau molecule are shared with paired helical filaments. Neuron 1988 1 9 817 825 2-s2.0-0024109687
-
(1988)
Neuron
, vol.1
, Issue.9
, pp. 817-825
-
-
Kosik, K.S.1
Orecchio, L.D.2
Binder, L.3
Trojanowski, J.Q.4
Lee, V.M.Y.5
Lee, G.6
-
28
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
DOI 10.1038/371346a0
-
Lazebnik Y. A., Kaufmann S. H., Desnoyers S., Poirier G. G., Earnshaw W. C., Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 1994 371 6495 346 347 2-s2.0-0028102478 10.1038/371346a0 (Pubitemid 24300618)
-
(1994)
Nature
, vol.371
, Issue.6495
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
29
-
-
14844328111
-
The role of caspase cleavage of tau in Alzheimer disease neuropathology
-
Cotman C. W., Poon W. W., Rissman R. A., Blurton-Jones M., The role of caspase cleavage of tau in Alzheimer disease neuropathology. Journal of Neuropathology and Experimental Neurology 2005 64 2 104 112 2-s2.0-14844328111 (Pubitemid 40349308)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.2
, pp. 104-112
-
-
Cotman, C.W.1
Poon, W.W.2
Rissman, R.A.3
Blurton-Jones, M.4
-
30
-
-
11144228296
-
Glycogen synthase kinase 3β induces caspase-cleaved tau aggregation in situ
-
DOI 10.1074/jbc.M403364200
-
Cho J. H., Johnson G. V. W., Glycogen synthase kinase 3 β induces caspase-cleaved tau aggregation in situ. Journal of Biological Chemistry 2004 279 52 54716 54723 2-s2.0-11144228296 10.1074/jbc.M403364200 (Pubitemid 40053216)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54716-54723
-
-
Cho, J.-H.1
Johnson, G.V.W.2
|