Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 10, 2009, Pages 1989-2004

  Aliev, Gjumrakch ^a,b   Palacios, Hector H ^a   Walrafen, Brianna ^a   Lipsitt, Amanda E ^c   Obrenovich, Mark E ^d   Morales, Ludis ^b  

^a University of San Antonio   (United States)

^b PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^c University of Texas Health Science Center   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer disease; Brain hypoperfusion; Mitochondrial failure; Neurodegeneration; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; APOLIPOPROTEIN E4; CARNITINE; LEVACECARNINE; LIPID; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

AGING; ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; BLOOD BRAIN BARRIER; BRAIN ATHEROSCLEROSIS; BRAIN BLOOD FLOW; BRAIN DAMAGE; BRAIN MITOCHONDRION; BRAIN PERFUSION; CEREBROVASCULAR DISEASE; DEGENERATIVE DISEASE; DEMENTIA; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFICACY; GENE DELETION; HUMAN; LIPID PEROXIDATION; NEUROPATHOLOGY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; REVIEW; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TREATMENT PLANNING; VASCULAR ENDOTHELIUM;

AGING; ALZHEIMER DISEASE; ANIMALS; BRAIN; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 68949152521     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.03.015     Document Type: Review

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