Loss of the m-AAA protease subunit AFG3L2 causes mitochondrial transport defects and tau hyperphosphorylation

EMBO Journal

Volumn 33, Issue 9, 2014, Pages 1011-1026

  Kondadi, Arun Kumar ^a   Wang, Shuaiyu ^a   Montagner, Sara ^a   Kladt, Nikolay ^b   Korwitz, Anne ^a   Martinelli, Paola ^a   Herholz, David ^a   Baker, Michael J ^a   Schauss, Astrid C ^b   Langer, Thomas ^a,b,c   Rugarli, Elena I ^a,b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

m AAA protease; mitochondrial transport; N acetylcysteine; Neurodegeneration; tau

Indexed keywords

ACETYLCYSTEINE; AFG3L2 PROTEASE; ALPHA TOCOPHEROL; DYNAMIN; OPA1 ENZYME; PROTEINASE; REACTIVE OXYGEN METABOLITE; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL TRANSPORT; CONTROLLED STUDY; DEGRADATION; MITOCHONDRIAL TRANSPORT; MITOCHONDRION; MOUSE; NERVE CELL; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION;

ACETYLCYSTEINE; ANIMALS; ATP-DEPENDENT PROTEASES; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EMBRYO, MAMMALIAN; MAP KINASE SIGNALING SYSTEM; METALLOPROTEASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL PROTEINS; NEURONS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; TAU PROTEINS;

EID: 84899885579     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201387009     Document Type: Article

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