Kavalactones protect neural cells against amyloid β peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation

Molecular Pharmacology

Volumn 73, Issue 6, 2008, Pages 1785-1795

  Wruck, Christoph J ^a,c   Götz, Mario E ^b   Herdegen, Thomas ^b   Varoga, Deike ^b   Brandenburg, Lars Ove ^a   Pufe, Thomas ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; KAWAIN; METHYSTICIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF2; YANGONIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; GENE EXPRESSION; GENETIC REGULATION; IN VITRO STUDY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; UPREGULATION; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; LACTONES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PC12 CELLS; RATS;

EID: 44249103744     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.042499     Document Type: Article

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