Loss of Axonal Mitochondria Promotes Tau-Mediated Neurodegeneration and Alzheimer's Disease-Related Tau Phosphorylation Via PAR-1

PLoS Genetics

Volumn 8, Issue 8, 2012, Pages

  Iijima Ando, Kanae ^a   Sekiya, Michiko ^a   Maruko Otake, Akiko ^a   Ohtake, Yosuke ^a   Suzuki, Emiko ^b,c   Lu, Bingwei ^d   Iijima, Koichi M ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; MICRORNA; MILTON PROTEIN; MIRO PROTEIN; PARTITIONING DEFECTIVE 1 PROTEIN; PHOSPHOTRANSFERASE; SERINE; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONAL MITOCHONDRIA; BRAIN MITOCHONDRION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE; GENE OVEREXPRESSION; GENE SILENCING; MICROTUBULE; MILTON GENE; MIRO GENE; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; PARTITIONING DEFECTIVE 1 GENE; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE;

ALZHEIMER DISEASE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AXONS; DROSOPHILA; DROSOPHILA PROTEINS; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MICROTUBULES; MITOCHONDRIA; NERVE DEGENERATION; PHOSPHORYLATION; RHO GTP-BINDING PROTEINS; TAU PROTEINS;

MAMMALIA;

EID: 84866150232     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002918     Document Type: Article

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