Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

Journal of Biological Chemistry

Volumn 280, Issue 25, 2005, Pages 23802-23814

  David, Della C ^a   Hauptmann, Susanne ^b   Scherping, Isabel ^b   Schuessel, Katrin ^b   Keil, Uta ^b   Rizzu, Patrizia ^c   Ravid, Rivka ^d   Dröse, Stefan ^b   Brandt, Ulrich ^b   Müller, Walter E ^b   Eckert, Anne ^e   Götz, Jürgen ^a,f  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b GOETHE UNIVERSITY   (Germany)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d NETHERLANDS BRAIN BANK   (Netherlands)

^e UNIVERSITY OF BASEL   (Switzerland)

^f UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; BIOCHEMISTRY; CELL MEMBRANES; CHROMOSOMES; CYTOLOGY; ENZYMES; GENETIC ENGINEERING; METABOLISM; PATHOLOGY;

ANTIOXIDANT ENZYMES; MITOCHONDRIAL RESPIRATION; SYNAPTIC PROTEINS; TRANSGENIC MICE;

MUTAGENESIS;

AMYLOID BETA PROTEIN; ANTIOXIDANT; MITOCHONDRIAL PROTEIN; PROTEIN MITOCHONDRIAL COMPLEX V; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL DEMENTIA WITH PARKINSONISM LINKED TO CHROMOSOME 17; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; LIPID PEROXIDATION; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; OXIDATIVE STRESS; PARKINSONISM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEOMICS; SYNAPSE; TRANSGENIC MOUSE; UPREGULATION;

ALZHEIMER DISEASE; ANIMALS; BRAIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MITOCHONDRIA; TAU PROTEINS; UP-REGULATION;

MUS MUSCULUS;

EID: 21244486781     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500356200     Document Type: Article

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