The unfolded protein response in retinal vascular diseases: Implications and therapeutic potential beyond protein folding

Progress in Retinal and Eye Research

Volumn 45, Issue , 2015, Pages 111-131

  Zhang, Sarah X ^a,b   Ma, Jacey H ^a,b,c   Bhatta, Maulasri ^a,b   Fliesler, Steven J ^a,b,d   Wang, Joshua J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b SUNY EYE INSTITUTE   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

^d VA WESTERN NEW YORK HEALTHCARE SYSTEM   (United States)

Author keywords

Angiogenesis; Endoplasmic reticulum stress; Endothelial cells; Retina; Unfolded protein response; VEGF

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; GROWTH FACTOR; INITIATION FACTOR 2; MEMBRANE PROTEIN; PROTEIN IRE1; VASCULOTROPIN; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; EYE PROTEIN;

AGE RELATED MACULAR DEGENERATION; ANGIOGENESIS; CELL SURVIVAL; DIABETIC RETINOPATHY; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIUM CELL; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; RETINA BLOOD VESSEL; RETINA NEOVASCULARIZATION; RETROLENTAL FIBROPLASIA; REVIEW; UNFOLDED PROTEIN RESPONSE; VASCULAR REMODELING; ANIMAL; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA DISEASE; SIGNAL TRANSDUCTION;

ANIMALS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; EYE PROTEINS; HUMANS; RETINAL DISEASES; RETINAL NEOVASCULARIZATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84925362119     PISSN: 13509462     EISSN: 18731635     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2014.12.001     Document Type: Review

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