Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development

Cancer Letters

Volumn 332, Issue 1, 2013, Pages 120-129

  Ruan, Qing ^a   Xi, Lei ^a   Boye, Sanford L ^b   Han, Song ^b   Chen, Zhi J ^a   Hauswirth, William W ^b   Lewin, Alfed S ^a   Boulton, Michael E ^a   Law, Brian K ^a   Jiang, Wen G ^c   Jiang, Huabei ^a   Cai, Jun ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Angiogenesis; Breast cancer; Photoacoustic imaging; ScAAV2; SiRNA; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; PARVOVIRUS VECTOR; PROTEIN IRE1; PROTEIN IRE1ALPHA; SELF COMPLEMENTARY ADENO ASSOCIATED VIRUS SEROTYPE 2 VECTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC GENE THERAPY; ARTICLE; BREAST CANCER; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTOACOUSTICS; PRIORITY JOURNAL; SELF COMPLEMENTARY ADENO ASSOCIATED VIRUS SEROTYPE 2; TUMOR VASCULARIZATION; UNFOLDED PROTEIN RESPONSE; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; BREAST NEOPLASMS; CAPSID PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; DEPENDOVIRUS; DNA-BINDING PROTEINS; ENDORIBONUCLEASES; ENDOTHELIAL CELLS; FEMALE; GENETIC THERAPY; GENETIC VECTORS; MICE; MICE, NUDE; MICROSCOPY; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PHOTOACOUSTIC TECHNIQUES; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC; TRANSFECTION; TUMOR BURDEN; UNFOLDED PROTEIN RESPONSE;

ADENO-ASSOCIATED VIRUS; MIRIDAE;

EID: 84875233197     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.11.016     Document Type: Article

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