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Volumn 51, Issue 6, 2010, Pages 2813-2826

The mouse retina as an angiogenesis model

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; OMEGA 3 FATTY ACID; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN; VASCULOTROPIN;

EID: 77953244680     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-5176     Document Type: Review
Times cited : (505)

References (190)
  • 1
    • 33845870432 scopus 로고    scopus 로고
    • Breakthrough of the year
    • Kennedy D. Breakthrough of the year. Science. 2006;314:1841.
    • (2006) Science , vol.314 , pp. 1841
    • Kennedy, D.1
  • 2
    • 11144356305 scopus 로고    scopus 로고
    • The prevalence of diabetic retinopathy among adults in the United States
    • Kempen JH, O'Colmain BJ, Leske MC, et al. The prevalence of diabetic retinopathy among adults in the United States. Arch Ophthalmol. 2004;122:552-563.
    • (2004) Arch Ophthalmol , vol.122 , pp. 552-563
    • Kempen, J.H.1    O'Colmain, B.J.2    Leske, M.C.3
  • 3
    • 34848907420 scopus 로고    scopus 로고
    • Overview of epidemiologic studies of diabetic retinopathy
    • Klein BE. Overview of epidemiologic studies of diabetic retinopathy. Ophthalmic Epidemiol. 2007;14:179-183.
    • (2007) Ophthalmic Epidemiol , vol.14 , pp. 179-183
    • Klein, B.E.1
  • 4
    • 1842530296 scopus 로고    scopus 로고
    • Causes and prevalence of visual impairment among adults in the United States
    • Congdon N, O'Colmain B, Klaver CC, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol. 2004;122:477-485.
    • (2004) Arch Ophthalmol , vol.122 , pp. 477-485
    • Congdon, N.1    O'Colmain, B.2    Klaver, C.C.3
  • 5
    • 11144354339 scopus 로고    scopus 로고
    • Prevalence of agerelated macular degeneration in the United States
    • Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of agerelated macular degeneration in the United States. Arch Ophthalmol. 2004;122:564-572.
    • (2004) Arch Ophthalmol , vol.122 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Munoz, B.3
  • 6
    • 0042192111 scopus 로고    scopus 로고
    • Retinopathy of prematurity: Molecular pathology and therapeutic strategies
    • Mechoulam H, Pierce EA. Retinopathy of prematurity: molecular pathology and therapeutic strategies. Am J Pharmacogenomics. 2003;3:261-277.
    • (2003) Am J Pharmacogenomics , vol.3 , pp. 261-277
    • Mechoulam, H.1    Pierce, E.A.2
  • 7
    • 34248531724 scopus 로고    scopus 로고
    • UpToDate Online, Accessed November 3, 2009
    • Paysse EA. Retinopathy of prematurity. UpToDate Online. Available at http://www.uptodate.com/home/index.html. Accessed November 3, 2009.
    • Retinopathy of Prematurity
    • Paysse, E.A.1
  • 8
    • 0031765632 scopus 로고    scopus 로고
    • Regression of vessels in the tunica vasculosa lentis is initiated by coordinated endothelial apoptosis: A role for vascular endothelial growth factor as a survival factor for endothelium
    • Mitchell CA, Risau W, Drexler HC. Regression of vessels in the tunica vasculosa lentis is initiated by coordinated endothelial apoptosis: a role for vascular endothelial growth factor as a survival factor for endothelium. Dev Dyn. 1998;213:322-333.
    • (1998) Dev Dyn , vol.213 , pp. 322-333
    • Mitchell, C.A.1    Risau, W.2    Drexler, H.C.3
  • 9
    • 12144289950 scopus 로고    scopus 로고
    • Vascular development in the retina and inner ear: Control by Norrin and Frizzled-4, a highaffinity ligand-receptor pair
    • Xu Q, Wang Y, Dabdoub A, et al. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a highaffinity ligand-receptor pair. Cell. 2004;116:883-895.
    • (2004) Cell , vol.116 , pp. 883-895
    • Xu, Q.1    Wang, Y.2    Dabdoub, A.3
  • 10
    • 0035378203 scopus 로고    scopus 로고
    • The multicenter study of Early Treatment for Retinopathy of Prematurity (ETROP)
    • Good WV, Hardy RJ. The multicenter study of Early Treatment for Retinopathy of Prematurity (ETROP). Ophthalmology. 2001;108: 1013-1014.
    • (2001) Ophthalmology , vol.108 , pp. 1013-1014
    • Good, W.V.1    Hardy, R.J.2
  • 11
    • 0027446536 scopus 로고
    • Prognostic factors in the natural course of retinopathy of prematurity: The Cryotherapy for Retinopathy of Prematurity Cooperative Group
    • Schaffer DB, Palmer EA, Plotsky DF, et al. Prognostic factors in the natural course of retinopathy of prematurity: The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology. 1993;100:230-237.
    • (1993) Ophthalmology , vol.100 , pp. 230-237
    • Schaffer, D.B.1    Palmer, E.A.2    Plotsky, D.F.3
  • 12
    • 84921430745 scopus 로고    scopus 로고
    • Peripheral retinal ablation for threshold retinopathy of prematurity in preterm infants
    • Andersen CC, Phelps DL. Peripheral retinal ablation for threshold retinopathy of prematurity in preterm infants. Cochrane Database Syst Rev. 2000;CD001693.
    • (2000) Cochrane Database Syst Rev
    • Andersen, C.C.1    Phelps, D.L.2
  • 13
    • 0035746627 scopus 로고    scopus 로고
    • Pathogenesis of retinopathy of prematurity
    • Smith LE. Pathogenesis of retinopathy of prematurity. Acta Paediatr Suppl. 2002;91:26-28.
    • (2002) Acta Paediatr Suppl , vol.91 , pp. 26-28
    • Smith, L.E.1
  • 14
    • 30344470460 scopus 로고    scopus 로고
    • Outcome of eyes developing retinal detachment during the Early Treatment for Retinopathy of Prematurity Study (ETROP)
    • Repka MX, Tung B, Good WV, et al. Outcome of eyes developing retinal detachment during the Early Treatment for Retinopathy of Prematurity Study (ETROP). Arch Ophthalmol. 2006;124:24-30.
    • (2006) Arch Ophthalmol , vol.124 , pp. 24-30
    • Repka, M.X.1    Tung, B.2    Good, W.V.3
  • 15
    • 0023576277 scopus 로고
    • Retinopathy of prematurity
    • Flynn JT. Retinopathy of prematurity. Pediatr Clin North Am.1987;34:1487-1516.
    • (1987) Pediatr Clin North Am , vol.34 , pp. 1487-1516
    • Flynn, J.T.1
  • 16
    • 0026063352 scopus 로고
    • Incidence and early course of retinopathy of prematurity: The Cryotherapy for Retinopathy of Prematurity Cooperative Group
    • Palmer EA, Flynn JT, Hardy RJ, et al. Incidence and early course of retinopathy of prematurity: The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology. 1991;98: 1628-1640.
    • (1991) Ophthalmology , vol.98 , pp. 1628-1640
    • Palmer, E.A.1    Flynn, J.T.2    Hardy, R.J.3
  • 17
    • 0034085171 scopus 로고    scopus 로고
    • Involution of retinopathy of prematurity: Cryotherapy for Retinopathy of Prematurity Cooperative Group
    • Repka MX, Palmer EA, Tung B. Involution of retinopathy of prematurity: Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol. 2000;118:645-649.
    • (2000) Arch Ophthalmol , vol.118 , pp. 645-649
    • Repka, M.X.1    Palmer, E.A.2    Tung, B.3
  • 19
    • 0028803509 scopus 로고
    • Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
    • Alon T, Hemo I, Itin A, Pe'er J, Stone J, Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med. 1995;1:1024-1028.
    • (1995) Nat Med , vol.1 , pp. 1024-1028
    • Alon, T.1    Hemo, I.2    Itin, A.3    Pe'er, J.4    Stone, J.5    Keshet, E.6
  • 20
    • 0028815295 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
    • Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci U S A. 1995;92:905-909.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 905-909
    • Pierce, E.A.1    Avery, R.L.2    Foley, E.D.3    Aiello, L.P.4    Smith, L.E.5
  • 21
    • 0029816808 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity
    • Pierce EA, Foley ED, Smith LE. Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity. Arch Ophthalmol. 1996;114:1219-1228.
    • (1996) Arch Ophthalmol , vol.114 , pp. 1219-1228
    • Pierce, E.A.1    Foley, E.D.2    Smith, L.E.3
  • 22
    • 0029074024 scopus 로고
    • Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
    • Stone J, Itin A, Alon T, et al. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci. 1995;15:4738-4747.
    • (1995) J Neurosci , vol.15 , pp. 4738-4747
    • Stone, J.1    Itin, A.2    Alon, T.3
  • 23
    • 14344249625 scopus 로고    scopus 로고
    • Association of genetic polymorphisms of vascular endothelial growth factor and risk for proliferative retinopathy of prematurity
    • Vannay A, Dunai G, Banyasz I, et al. Association of genetic polymorphisms of vascular endothelial growth factor and risk for proliferative retinopathy of prematurity. Pediatr Res. 2005;57: 396-398.
    • (2005) Pediatr Res , vol.57 , pp. 396-398
    • Vannay, A.1    Dunai, G.2    Banyasz, I.3
  • 24
    • 0031150509 scopus 로고    scopus 로고
    • Histopathology and vascular endothelial growth factor in untreated and diode laser-treated retinopathy of prematurity
    • Young TL, Anthony DC, Pierce E, Foley E, Smith LE. Histopathology and vascular endothelial growth factor in untreated and diode laser-treated retinopathy of prematurity. J AAPOS. 1997;1: 105-110.
    • (1997) J AAPOS , vol.1 , pp. 105-110
    • Young, T.L.1    Anthony, D.C.2    Pierce, E.3    Foley, E.4    Smith, L.E.5
  • 25
    • 84959071336 scopus 로고
    • Experimental approach to the pathogenesis of retrolental fibroplasia. I. Changes of the eye induced by exposure of newborn mice to concentrated oxygen
    • Gyllensten LJ, Hellstrom BE. Experimental approach to the pathogenesis of retrolental fibroplasia. I. Changes of the eye induced by exposure of newborn mice to concentrated oxygen. Acta Paediatr Suppl. 1954;43:131-148.
    • (1954) Acta Paediatr Suppl , vol.43 , pp. 131-148
    • Gyllensten, L.J.1    Hellstrom, B.E.2
  • 26
    • 25144451336 scopus 로고    scopus 로고
    • WNT7b mediates macrophageinduced programmed cell death in patterning of the vasculature
    • Lobov IB, Rao S, Carroll TJ, et al. WNT7b mediates macrophageinduced programmed cell death in patterning of the vasculature. Nature. 2005;437:417-421.
    • (2005) Nature , vol.437 , pp. 417-421
    • Lobov, I.B.1    Rao, S.2    Carroll, T.J.3
  • 27
    • 58149357540 scopus 로고    scopus 로고
    • An essential role for frizzled 5 in mammalian ocular development
    • Liu C, Nathans J. An essential role for frizzled 5 in mammalian ocular development. Development. 2008;135:3567-3576.
    • (2008) Development , vol.135 , pp. 3567-3576
    • Liu, C.1    Nathans, J.2
  • 28
    • 37549046071 scopus 로고    scopus 로고
    • The Wnt signaling pathway in familial exudative vitreoretinopathy and Norrie disease
    • Warden SM, Andreoli CM, Mukai S. The Wnt signaling pathway in familial exudative vitreoretinopathy and Norrie disease. Semin Ophthalmol. 2007;22:211-217.
    • (2007) Semin Ophthalmol , vol.22 , pp. 211-217
    • Warden, S.M.1    Andreoli, C.M.2    Mukai, S.3
  • 29
    • 0036789449 scopus 로고    scopus 로고
    • Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy
    • Robitaille J, MacDonald ML, Kaykas A, et al. Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy. Nat Genet. 2002;32:326-330.
    • (2002) Nat Genet , vol.32 , pp. 326-330
    • Robitaille, J.1    Macdonald, M.L.2    Kaykas, A.3
  • 30
    • 12144288372 scopus 로고    scopus 로고
    • Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q
    • Toomes C, Bottomley HM, Jackson RM, et al. Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q. Am J Hum Genet. 2004;74:721-730.
    • (2004) Am J Hum Genet , vol.74 , pp. 721-730
    • Toomes, C.1    Bottomley, H.M.2    Jackson, R.M.3
  • 31
    • 6344241957 scopus 로고    scopus 로고
    • Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5
    • Jiao X, Ventruto V, Trese MT, Shastry BS, Hejtmancik JF. Autosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5. Am J Hum Genet. 2004;75:878-884.
    • (2004) Am J Hum Genet , vol.75 , pp. 878-884
    • Jiao, X.1    Ventruto, V.2    Trese, M.T.3    Shastry, B.S.4    Hejtmancik, J.F.5
  • 32
    • 0027367772 scopus 로고
    • A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy
    • Chen ZY, Battinelli EM, Fielder A, et al. A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy. Nat Genet. 1993;5:180-183.
    • (1993) Nat Genet , vol.5 , pp. 180-183
    • Chen, Z.Y.1    Battinelli, E.M.2    Fielder, A.3
  • 33
    • 0030902358 scopus 로고    scopus 로고
    • Identification of novel missense mutations in the Norrie disease gene associated with one X-linked and four sporadic cases of familial exudative vitreoretinopathy
    • Shastry BS, Hejtmancik JF, Trese MT. Identification of novel missense mutations in the Norrie disease gene associated with one X-linked and four sporadic cases of familial exudative vitreoretinopathy. Hum Mutat. 1997;9:396-401.
    • (1997) Hum Mutat , vol.9 , pp. 396-401
    • Shastry, B.S.1    Hejtmancik, J.F.2    Trese, M.T.3
  • 34
    • 22844443861 scopus 로고    scopus 로고
    • Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes
    • Qin M, Hayashi H, Oshima K, Tahira T, Hayashi K, Kondo H. Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes. Hum Mutat. 2005;26:104-112.
    • (2005) Hum Mutat , vol.26 , pp. 104-112
    • Qin, M.1    Hayashi, H.2    Oshima, K.3    Tahira, T.4    Hayashi, K.5    Kondo, H.6
  • 35
    • 33646869290 scopus 로고    scopus 로고
    • Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina
    • Dorrell MI, Friedlander M. Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina. Prog Retin Eye Res. 2006;25:277-295.
    • (2006) Prog Retin Eye Res , vol.25 , pp. 277-295
    • Dorrell, M.I.1    Friedlander, M.2
  • 37
    • 0037039350 scopus 로고    scopus 로고
    • A fragment of human TrpRS as a potent antagonist of ocular angiogenesis
    • Otani A, Slike BM, Dorrell MI, et al. A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proc Natl Acad Sci U S A. 2002;99:178-183.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 178-183
    • Otani, A.1    Slike, B.M.2    Dorrell, M.I.3
  • 39
    • 30744476478 scopus 로고    scopus 로고
    • Retinal angiogenesis in development and disease
    • Gariano RF, Gardner TW. Retinal angiogenesis in development and disease. Nature. 2005;438:960-966.
    • (2005) Nature , vol.438 , pp. 960-966
    • Gariano, R.F.1    Gardner, T.W.2
  • 40
    • 33947330375 scopus 로고    scopus 로고
    • Development of the retinal vasculature
    • Fruttiger M. Development of the retinal vasculature. Angiogenesis. 2007;10:77-88.
    • (2007) Angiogenesis , vol.10 , pp. 77-88
    • Fruttiger, M.1
  • 42
    • 0027424155 scopus 로고
    • Microscopic visualization of the retina by angiography with high-molecular-weight fluorescein-labeled dextrans in the mouse
    • D'Amato R, Wesolowski E, Smith LE. Microscopic visualization of the retina by angiography with high-molecular-weight fluorescein-labeled dextrans in the mouse. Microvasc Res. 1993;46:135-142.
    • (1993) Microvasc Res , vol.46 , pp. 135-142
    • D'amato, R.1    Wesolowski, E.2    Smith, L.E.3
  • 44
    • 0036174063 scopus 로고    scopus 로고
    • Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms
    • Stalmans I, Ng YS, Rohan R, et al. Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest. 2002;109:327-336.
    • (2002) J Clin Invest , vol.109 , pp. 327-336
    • Stalmans, I.1    Ng, Y.S.2    Rohan, R.3
  • 45
    • 0037815292 scopus 로고    scopus 로고
    • VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
    • Gerhardt H, Golding M, Fruttiger M, et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 2003;161:1163-1177.
    • (2003) J Cell Biol , vol.161 , pp. 1163-1177
    • Gerhardt, H.1    Golding, M.2    Fruttiger, M.3
  • 46
    • 66449123068 scopus 로고    scopus 로고
    • The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
    • Benedito R, Roca C, Sorensen I, et al. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell. 2009;137: 1124-1135.
    • (2009) Cell , vol.137 , pp. 1124-1135
    • Benedito, R.1    Roca, C.2    Sorensen, I.3
  • 47
    • 33847046849 scopus 로고    scopus 로고
    • Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
    • Hellstrom M, Phng LK, Hofmann JJ, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 2007;445:776-780.
    • (2007) Nature , vol.445 , pp. 776-780
    • Hellstrom, M.1    Phng, L.K.2    Hofmann, J.J.3
  • 48
    • 33847635620 scopus 로고    scopus 로고
    • Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting
    • Lobov IB, Renard RA, Papadopoulos N, et al. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad Sci U S A. 2007;104:3219-3224.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3219-3224
    • Lobov, I.B.1    Renard, R.A.2    Papadopoulos, N.3
  • 50
    • 1942425164 scopus 로고    scopus 로고
    • Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina
    • Dorrell MI, Otani A, Aguilar E, Moreno SK, Friedlander M. Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina. Blood. 2004;103: 3420-3427.
    • (2004) Blood , vol.103 , pp. 3420-3427
    • Dorrell, M.I.1    Otani, A.2    Aguilar, E.3    Moreno, S.K.4    Friedlander, M.5
  • 51
    • 9644268242 scopus 로고    scopus 로고
    • Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineagenegative hematopoietic stem cells
    • Otani A, Dorrell MI, Kinder K, et al. Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineagenegative hematopoietic stem cells. J Clin Invest. 2004;114:765-774.
    • (2004) J Clin Invest , vol.114 , pp. 765-774
    • Otani, A.1    Dorrell, M.I.2    Kinder, K.3
  • 52
    • 0036732459 scopus 로고    scopus 로고
    • Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis
    • Otani A, Kinder K, Ewalt K, Otero FJ, Schimmel P, Friedlander M. Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis. Nat Med. 2002;8:1004-1010.
    • (2002) Nat Med , vol.8 , pp. 1004-1010
    • Otani, A.1    Kinder, K.2    Ewalt, K.3    Otero, F.J.4    Schimmel, P.5    Friedlander, M.6
  • 53
    • 69849084521 scopus 로고    scopus 로고
    • Therapeutic potential of manipulating VEGF splice isoforms in oncology
    • Rennel ES, Harper SJ, Bates DO. Therapeutic potential of manipulating VEGF splice isoforms in oncology. Future Oncol. 2009;5: 703-712.
    • (2009) Future Oncol , vol.5 , pp. 703-712
    • Rennel, E.S.1    Harper, S.J.2    Bates, D.O.3
  • 54
  • 55
    • 3242686399 scopus 로고    scopus 로고
    • Animal models of oxygen-induced retinopathy
    • Madan A, Penn JS. Animal models of oxygen-induced retinopathy. Front Biosci. 2003;8:d1030-d1043.
    • (2003) Front Biosci , vol.8
    • Madan, A.1    Penn, J.S.2
  • 56
    • 0026681569 scopus 로고
    • Degeneration of astrocytes in feline retinopathy of prematurity causes failure of the blood-retinal barrier
    • Chan-Ling T, Stone J. Degeneration of astrocytes in feline retinopathy of prematurity causes failure of the blood-retinal barrier. Invest Ophthalmol Vis Sci. 1992;33:2148-2159.
    • (1992) Invest Ophthalmol Vis Sci , vol.33 , pp. 2148-2159
    • Chan-Ling, T.1    Stone, J.2
  • 57
    • 0026749986 scopus 로고
    • Vascular changes and their mechanisms in the feline model of retinopathy of prematurity
    • Chan-Ling T, Tout S, Hollander H, Stone J. Vascular changes and their mechanisms in the feline model of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1992;33:2128-2147.
    • (1992) Invest Ophthalmol Vis Sci , vol.33 , pp. 2128-2147
    • Chan-Ling, T.1    Tout, S.2    Hollander, H.3    Stone, J.4
  • 58
    • 0023894735 scopus 로고
    • Reduced severity of oxygen-induced retinopathy in kittens recovered in 28% oxygen
    • Phelps DL. Reduced severity of oxygen-induced retinopathy in kittens recovered in 28% oxygen. Pediatr Res. 1988;24:106-109.
    • (1988) Pediatr Res , vol.24 , pp. 106-109
    • Phelps, D.L.1
  • 59
    • 0031706503 scopus 로고    scopus 로고
    • Clinical and histopathologic features of canine oxygen-induced proliferative retinopathy
    • McLeod DS, D'Anna SA, Lutty GA. Clinical and histopathologic features of canine oxygen-induced proliferative retinopathy. Invest Ophthalmol Vis Sci. 1998;39:1918-1932.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1918-1932
    • McLeod, D.S.1    D'anna, S.A.2    Lutty, G.A.3
  • 60
    • 0027400804 scopus 로고
    • Variable oxygen exposure causes preretinal neovascularization in the newborn rat
    • Penn JS, Tolman BL, Lowery LA. Variable oxygen exposure causes preretinal neovascularization in the newborn rat. Invest Ophthalmol Vis Sci. 1993;34:576-585.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 576-585
    • Penn, J.S.1    Tolman, B.L.2    Lowery, L.A.3
  • 62
    • 20444429446 scopus 로고    scopus 로고
    • Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization
    • Chan CK, Pham LN, Zhou J, Spee C, Ryan SJ, Hinton DR. Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization. Lab Invest. 2005;85:721-733.
    • (2005) Lab Invest , vol.85 , pp. 721-733
    • Chan, C.K.1    Pham, L.N.2    Zhou, J.3    Spee, C.4    Ryan, S.J.5    Hinton, D.R.6
  • 63
    • 33845297656 scopus 로고    scopus 로고
    • Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy
    • Ritter MR, Banin E, Moreno SK, Aguilar E, Dorrell MI, Friedlander M. Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy. J Clin Invest.2006;116:3266-3276.
    • (2006) J Clin Invest , vol.116 , pp. 3266-3276
    • Ritter, M.R.1    Banin, E.2    Moreno, S.K.3    Aguilar, E.4    Dorrell, M.I.5    Friedlander, M.6
  • 64
    • 0036820720 scopus 로고    scopus 로고
    • Incidence and severity of neovascularization in oxygen- and metabolic acidosis-induced retinopathy depend on rat source
    • Kitzmann A, Leske D, Chen Y, Kendall A, Lanier W, Holmes J. Incidence and severity of neovascularization in oxygen- and metabolic acidosis-induced retinopathy depend on rat source. Curr Eye Res. 2002;25:215-220.
    • (2002) Curr Eye Res , vol.25 , pp. 215-220
    • Kitzmann, A.1    Leske, D.2    Chen, Y.3    Kendall, A.4    Lanier, W.5    Holmes, J.6
  • 65
    • 0034566953 scopus 로고    scopus 로고
    • Poor postnatal weight gain: A risk factor for severe retinopathy of prematurity
    • Wallace DK, Kylstra JA, Phillips SJ, Hall JG. Poor postnatal weight gain: a risk factor for severe retinopathy of prematurity. J AAPOS. 2000;4:343-347.
    • (2000) J AAPOS , vol.4 , pp. 343-347
    • Wallace, D.K.1    Kylstra, J.A.2    Phillips, S.J.3    Hall, J.G.4
  • 66
    • 0038310406 scopus 로고    scopus 로고
    • Perinatal growth characteristics and associated risk of developing threshold retinopathy of prematurity
    • Allegaert K, Vanhole C, Casteels I, et al. Perinatal growth characteristics and associated risk of developing threshold retinopathy of prematurity. J AAPOS. 2003;7:34-37.
    • (2003) J AAPOS , vol.7 , pp. 34-37
    • Allegaert, K.1    Vanhole, C.2    Casteels, I.3
  • 67
    • 33845495388 scopus 로고    scopus 로고
    • Longitudinal postnatal weight and insulin-like growth factor I measurements in the prediction of retinopathy of prematurity
    • Lofqvist C, Andersson E, Sigurdsson J, et al. Longitudinal postnatal weight and insulin-like growth factor I measurements in the prediction of retinopathy of prematurity. Arch Ophthalmol. 2006;124:1711-1718.
    • (2006) Arch Ophthalmol , vol.124 , pp. 1711-1718
    • Lofqvist, C.1    Andersson, E.2    Sigurdsson, J.3
  • 68
    • 77649197682 scopus 로고    scopus 로고
    • New insights into the development of retinopathy of prematurity: Importance of early weight gain
    • Hellstrom A, Ley D, Hansen-Pupp I, et al. New insights into the development of retinopathy of prematurity: importance of early weight gain. Acta Paediatr. 2010;99:502-508.
    • (2010) Acta Paediatr , vol.99 , pp. 502-508
    • Hellstrom, A.1    Ley, D.2    Hansen-Pupp, I.3
  • 69
    • 65649119585 scopus 로고    scopus 로고
    • Validation of a new retinopathy of prematurity screening method monitoring longitudinal postnatal weight and insulinlike growth factor I
    • Lofqvist C, Hansen-Pupp I, Andersson E, et al. Validation of a new retinopathy of prematurity screening method monitoring longitudinal postnatal weight and insulinlike growth factor I. Arch Ophthalmol. 2009;127:622-627.
    • (2009) Arch Ophthalmol , vol.127 , pp. 622-627
    • Lofqvist, C.1    Hansen-Pupp, I.2    Andersson, E.3
  • 70
    • 67349174962 scopus 로고    scopus 로고
    • Weight gain measured at 6 weeks after birth as a predictor for severe retinopathy of prematurity: Study with 317 very low birth weight preterm babies
    • Fortes Filho JB, Bonomo PP, Maia M, Procianoy RS. Weight gain measured at 6 weeks after birth as a predictor for severe retinopathy of prematurity: study with 317 very low birth weight preterm babies. Graefes Arch Clin Exp Ophthalmol. 2009;247:831-836.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 831-836
    • Fortes, F.J.B.1    Bonomo, P.P.2    Maia, M.3    Procianoy, R.S.4
  • 71
    • 65349154512 scopus 로고    scopus 로고
    • Early weight gain predicts retinopathy in preterm infants: New, simple, efficient approach to screening
    • Hellstrom A, Hard AL, Engstrom E, et al. Early weight gain predicts retinopathy in preterm infants: new, simple, efficient approach to screening. Pediatrics. 2009;123:e638-e645.
    • (2009) Pediatrics , vol.123
    • Hellstrom, A.1    Hard, A.L.2    Engstrom, E.3
  • 72
    • 61949479859 scopus 로고    scopus 로고
    • Oxygen-induced retinopathy in mice: Amplification by neonatal IGF-I deficit and attenuation by IGF-I administration
    • Vanhaesebrouck S, Daniels H, Moons L, Vanhole C, Carmeliet P, De Zegher F. Oxygen-induced retinopathy in mice: amplification by neonatal IGF-I deficit and attenuation by IGF-I administration. Pediatr Res. 2009;65:307-310.
    • (2009) Pediatr Res , vol.65 , pp. 307-310
    • Vanhaesebrouck, S.1    Daniels, H.2    Moons, L.3    Vanhole, C.4    Carmeliet, P.5    de Zegher, F.6
  • 73
    • 70350036077 scopus 로고    scopus 로고
    • Quantification of oxygen-induced retinopathy in the mouse: A model of vessel loss, vessel regrowth and pathological angiogenesis
    • Connor KM, Krah NM, Dennison RJ, et al. Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat Protoc. 2009; 4:1565-1573.
    • (2009) Nat Protoc , vol.4 , pp. 1565-1573
    • Connor, K.M.1    Krah, N.M.2    Dennison, R.J.3
  • 74
    • 0037390258 scopus 로고    scopus 로고
    • Retinal oxygen: Fundamental and clinical aspects
    • Wangsa-Wirawan ND, Linsenmeier RA. Retinal oxygen: fundamental and clinical aspects. Arch Ophthalmol. 2003;121:547-557.
    • (2003) Arch Ophthalmol , vol.121 , pp. 547-557
    • Wangsa-Wirawan, N.D.1    Linsenmeier, R.A.2
  • 75
    • 68549132280 scopus 로고    scopus 로고
    • Kinetics of retinal vaso-obliteration and neovascularisation in the oxygen-induced retinopathy (OIR) mouse model
    • Lange C, Ehlken C, Stahl A, Martin G, Hansen L, Agostini HT. Kinetics of retinal vaso-obliteration and neovascularisation in the oxygen-induced retinopathy (OIR) mouse model. Graefes Arch Clin Exp Ophthalmol. 2009;247:1205-1211.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 1205-1211
    • Lange, C.1    Ehlken, C.2    Stahl, A.3    Martin, G.4    Hansen, L.5    Agostini, H.T.6
  • 76
    • 0036152407 scopus 로고    scopus 로고
    • Effects of sustained hyperoxia on revascularization in experimental retinopathy of prematurity
    • Gu X, Samuel S, El-Shabrawey M, et al. Effects of sustained hyperoxia on revascularization in experimental retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2002;43:496-502.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 496-502
    • Gu, X.1    Samuel, S.2    El-Shabrawey, M.3
  • 77
    • 0032932138 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha is increased in ischemic retina: Temporal and spatial correlation with VEGF expression
    • Ozaki H, Yu AY, Della N, et al. Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression. Invest Ophthalmol Vis Sci. 1999;40:182-189.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 182-189
    • Ozaki, H.1    Yu, A.Y.2    Della, N.3
  • 78
    • 62649142360 scopus 로고    scopus 로고
    • Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy
    • Chen J, Connor KM, Aderman CM, Willett KL, Aspegren OP, Smith LE. Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy. Invest Ophthalmol Vis Sci. 2009;50:1329-1335.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1329-1335
    • Chen, J.1    Connor, K.M.2    Aderman, C.M.3    Willett, K.L.4    Aspegren, O.P.5    Smith, L.E.6
  • 79
    • 0032758384 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin- like growth factor-1 receptor
    • Smith LE, Shen W, Perruzzi C, et al. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin- like growth factor-1 receptor. Nat Med. 1999;5:1390-1395.
    • (1999) Nat Med , vol.5 , pp. 1390-1395
    • Smith, L.E.1    Shen, W.2    Perruzzi, C.3
  • 80
    • 45549090431 scopus 로고    scopus 로고
    • Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model
    • Saito Y, Uppal A, Byfield G, Budd S, Hartnett ME. Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model. Invest Ophthalmol Vis Sci. 2008;49:1591-1598.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1591-1598
    • Saito, Y.1    Uppal, A.2    Byfield, G.3    Budd, S.4    Hartnett, M.E.5
  • 81
    • 53149121027 scopus 로고    scopus 로고
    • MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy
    • Davies MH, Stempel AJ, Powers MR. MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy. Invest Ophthalmol Vis Sci. 2008;49:4195-4202.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4195-4202
    • Davies, M.H.1    Stempel, A.J.2    Powers, M.R.3
  • 82
    • 0028786651 scopus 로고
    • Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
    • Aiello LP, Pierce EA, Foley ED, et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci U S A. 1995;92:10457-10461.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10457-10461
    • Aiello, L.P.1    Pierce, E.A.2    Foley, E.D.3
  • 84
    • 13244271330 scopus 로고    scopus 로고
    • An increase in superoxide dismutase ameliorates oxygen-induced retinopathy in transgenic mice
    • Spierer A, Rabinowitz R, Pri-Chen S, Rosner M. An increase in superoxide dismutase ameliorates oxygen-induced retinopathy in transgenic mice. Eye. 2005;19:86-91.
    • (2005) Eye , vol.19 , pp. 86-91
    • Spierer, A.1    Rabinowitz, R.2    Pri-Chen, S.3    Rosner, M.4
  • 85
    • 33744729949 scopus 로고    scopus 로고
    • T2-TrpRS inhibits preretinal neovascularization and enhances physiological vascular regrowth in OIR as assessed by a new method of quantification
    • Banin E, Dorrell MI, Aguilar E, et al. T2-TrpRS inhibits preretinal neovascularization and enhances physiological vascular regrowth in OIR as assessed by a new method of quantification. Invest Ophthalmol Vis Sci. 2006;47:2125-2134.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2125-2134
    • Banin, E.1    Dorrell, M.I.2    Aguilar, E.3
  • 86
    • 70349556527 scopus 로고    scopus 로고
    • Computer-aided quantification of retinal neovascularization
    • Stahl A, Connor KM, Sapieha P, et al. Computer-aided quantification of retinal neovascularization. Angiogenesis. 2009;12:297-301.
    • (2009) Angiogenesis , vol.12 , pp. 297-301
    • Stahl, A.1    Connor, K.M.2    Sapieha, P.3
  • 87
    • 0030947071 scopus 로고    scopus 로고
    • Therapeutic effect of liposomal superoxide dismutase in an animal model of retinopathy of prematurity
    • Niesman MR, Johnson KA, Penn JS. Therapeutic effect of liposomal superoxide dismutase in an animal model of retinopathy of prematurity. Neurochem Res. 1997;22:597-605.
    • (1997) Neurochem Res , vol.22 , pp. 597-605
    • Niesman, M.R.1    Johnson, K.A.2    Penn, J.S.3
  • 88
    • 0036197157 scopus 로고    scopus 로고
    • Nitric oxide is proangiogenic in the retina and choroid
    • Ando A, Yang A, Mori K, et al. Nitric oxide is proangiogenic in the retina and choroid. J Cell Physiol. 2002;191:116-124.
    • (2002) J Cell Physiol , vol.191 , pp. 116-124
    • Ando, A.1    Yang, A.2    Mori, K.3
  • 89
    • 7444239689 scopus 로고    scopus 로고
    • Redox-dependent effects of nitric oxide on microvascular integrity in oxygen-induced retinopathy
    • Beauchamp MH, Sennlaub F, Speranza G, et al. Redox-dependent effects of nitric oxide on microvascular integrity in oxygen-induced retinopathy. Free Radic Biol Med. 2004;37:1885-1894.
    • (2004) Free Radic Biol Med , vol.37 , pp. 1885-1894
    • Beauchamp, M.H.1    Sennlaub, F.2    Speranza, G.3
  • 90
    • 28644431994 scopus 로고    scopus 로고
    • Transarachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration
    • Kermorvant-Duchemin E, Sennlaub F, Sirinyan M, et al. Transarachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. Nat Med. 2005;11:1339-1345.
    • (2005) Nat Med , vol.11 , pp. 1339-1345
    • Kermorvant-Duchemin, E.1    Sennlaub, F.2    Sirinyan, M.3
  • 91
    • 13244257265 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy
    • Gardiner TA, Gibson DS, de Gooyer TE, de la Cruz VF, McDonald DM, Stitt AW. Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy. Am J Pathol. 2005;166:637-644.
    • (2005) Am J Pathol , vol.166 , pp. 637-644
    • Gardiner, T.A.1    Gibson, D.S.2    de Gooyer, T.E.3    de la Cruz, V.F.4    McDonald, D.M.5    Stitt, A.W.6
  • 92
    • 0037902889 scopus 로고    scopus 로고
    • Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease
    • Ishida S, Yamashiro K, Usui T, et al. Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease. Nat Med. 2003;9:781-788.
    • (2003) Nat Med , vol.9 , pp. 781-788
    • Ishida, S.1    Yamashiro, K.2    Usui, T.3
  • 93
    • 34247169524 scopus 로고    scopus 로고
    • Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor-deficient mice
    • Kociok N, Radetzky S, Krohne TU, Gavranic C, Joussen AM. Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor-deficient mice. Invest Ophthalmol Vis Sci. 2006;47:5057-5065.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 5057-5065
    • Kociok, N.1    Radetzky, S.2    Krohne, T.U.3    Gavranic, C.4    Joussen, A.M.5
  • 94
    • 0035717940 scopus 로고    scopus 로고
    • Dexamethasone alters TNF-alpha expression in retinopathy
    • Yossuck P, Yan Y, Tadesse M, Higgins RD. Dexamethasone alters TNF-alpha expression in retinopathy. Mol Genet Metab. 2001;72: 164-167.
    • (2001) Mol Genet Metab , vol.72 , pp. 164-167
    • Yossuck, P.1    Yan, Y.2    Tadesse, M.3    Higgins, R.D.4
  • 95
    • 0242665386 scopus 로고    scopus 로고
    • Angiopoietin/Tek interactions regulate mmp-9 expression and retinal neovascularization
    • Das A, Fanslow W, Cerretti D, Warren E, Talarico N, McGuire P. Angiopoietin/Tek interactions regulate mmp-9 expression and retinal neovascularization. Lab Invest. 2003;83:1637-1645.
    • (2003) Lab Invest , vol.83 , pp. 1637-1645
    • Das, A.1    Fanslow, W.2    Cerretti, D.3    Warren, E.4    Talarico, N.5    McGuire, P.6
  • 96
    • 33847006938 scopus 로고    scopus 로고
    • Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin- 2 overexpression
    • Feng Y, vom Hagen F, Pfister F, et al. Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin- 2 overexpression. Thromb Haemost. 2007;97:99-108.
    • (2007) Thromb Haemost , vol.97 , pp. 99-108
    • Feng, Y.1    vom Hagen, F.2    Pfister, F.3
  • 97
    • 66749176681 scopus 로고    scopus 로고
    • Decreased hypoxia-induced neovascularization in angiopoietin- 2 heterozygous knockout mouse through reduced MMP activity
    • Feng Y, Wang Y, Pfister F, Hillebrands JL, Deutsch U, Hammes HP. Decreased hypoxia-induced neovascularization in angiopoietin- 2 heterozygous knockout mouse through reduced MMP activity. Cell Physiol Biochem. 2009;23:277-284.
    • (2009) Cell Physiol Biochem , vol.23 , pp. 277-284
    • Feng, Y.1    Wang, Y.2    Pfister, F.3    Hillebrands, J.L.4    Deutsch, U.5    Hammes, H.P.6
  • 99
    • 0037088694 scopus 로고    scopus 로고
    • Down-regulation of vascular endothelial growth factor and up-regulation of pigment epithelium-derived factor: A possible mechanism for the anti-angiogenic activity of plasminogen kringle 5
    • Gao G, Li Y, Gee S, et al. Down-regulation of vascular endothelial growth factor and up-regulation of pigment epithelium-derived factor: a possible mechanism for the anti-angiogenic activity of plasminogen kringle 5. J Biol Chem. 2002;277:9492-9497.
    • (2002) J Biol Chem , vol.277 , pp. 9492-9497
    • Gao, G.1    Li, Y.2    Gee, S.3
  • 100
    • 39549088686 scopus 로고    scopus 로고
    • Neutralizing antibody to VEGF reduces intravitreous neovascularization and may not interfere with ongoing intraretinal vascularization in a rat model of retinopathy of prematurity
    • Geisen P, Peterson LJ, Martiniuk D, Uppal A, Saito Y, Hartnett ME. Neutralizing antibody to VEGF reduces intravitreous neovascularization and may not interfere with ongoing intraretinal vascularization in a rat model of retinopathy of prematurity. Mol Vis.2008;14:345-357.
    • (2008) Mol Vis , vol.14 , pp. 345-357
    • Geisen, P.1    Peterson, L.J.2    Martiniuk, D.3    Uppal, A.4    Saito, Y.5    Hartnett, M.E.6
  • 101
    • 0030044257 scopus 로고    scopus 로고
    • Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity
    • Stone J, Chan-Ling T, Pe'er J, Itin A, Gnessin H, Keshet E. Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1996;37:290-299.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 290-299
    • Stone, J.1    Chan-Ling, T.2    Pe'er, J.3    Itin, A.4    Gnessin, H.5    Keshet, E.6
  • 102
    • 0030013610 scopus 로고    scopus 로고
    • Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy
    • Robinson GS, Pierce EA, Rook SL, Foley E, Webb R, Smith LE. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy. Proc Natl Acad Sci U S A. 1996;93:4851-4856.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4851-4856
    • Robinson, G.S.1    Pierce, E.A.2    Rook, S.L.3    Foley, E.4    Webb, R.5    Smith, L.E.6
  • 103
    • 85047699046 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1
    • Bainbridge JW, Mistry A, De Alwis M, et al. Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther. 2002;9:320-326.
    • (2002) Gene Ther , vol.9 , pp. 320-326
    • Bainbridge, J.W.1    Mistry, A.2    de Alwis, M.3
  • 104
    • 0033882794 scopus 로고    scopus 로고
    • Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization
    • Ozaki H, Seo MS, Ozaki K, et al. Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization. Am J Pathol. 2000;156:697-707.
    • (2000) Am J Pathol , vol.156 , pp. 697-707
    • Ozaki, H.1    Seo, M.S.2    Ozaki, K.3
  • 105
    • 0346734123 scopus 로고    scopus 로고
    • Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: Mechanism of pericyte-induced vascular survival in vivo
    • Shih SC, Ju M, Liu N, Mo JR, Ney JJ, Smith LE. Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: mechanism of pericyte-induced vascular survival in vivo. Proc Natl Acad Sci U S A. 2003;100:15859-15864.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15859-15864
    • Shih, S.C.1    Ju, M.2    Liu, N.3    Mo, J.R.4    Ney, J.J.5    Smith, L.E.6
  • 106
    • 85047693011 scopus 로고    scopus 로고
    • Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity
    • Shih SC, Ju M, Liu N, Smith LE. Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity. J Clin Invest. 2003;112:50-57.
    • (2003) J Clin Invest , vol.112 , pp. 50-57
    • Shih, S.C.1    Ju, M.2    Liu, N.3    Smith, L.E.4
  • 107
    • 23944523376 scopus 로고    scopus 로고
    • Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy
    • Watanabe D, Suzuma K, Matsui S, et al. Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy. N Engl J Med. 2005;353:782-792.
    • (2005) N Engl J Med , vol.353 , pp. 782-792
    • Watanabe, D.1    Suzuma, K.2    Matsui, S.3
  • 108
    • 0037416792 scopus 로고    scopus 로고
    • HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin
    • Morita M, Ohneda O, Yamashita T, et al. HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin. EMBO J. 2003;22:1134-1146.
    • (2003) EMBO J , vol.22 , pp. 1134-1146
    • Morita, M.1    Ohneda, O.2    Yamashita, T.3
  • 109
    • 0036678821 scopus 로고    scopus 로고
    • Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury
    • Junk AK, Mammis A, Savitz SI, et al. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2002;99:10659-10664.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10659-10664
    • Junk, A.K.1    Mammis, A.2    Savitz, S.I.3
  • 110
    • 38849162389 scopus 로고    scopus 로고
    • Erythropoietin deficiency decreases vascular stability in mice
    • Chen J, Connor KM, Aderman CM, Smith LE. Erythropoietin deficiency decreases vascular stability in mice. J Clin Invest.2008;118:526-533.
    • (2008) J Clin Invest , vol.118 , pp. 526-533
    • Chen, J.1    Connor, K.M.2    Aderman, C.M.3    Smith, L.E.4
  • 112
    • 78049307897 scopus 로고    scopus 로고
    • Vitreal levels of erythropoietin are increased in patients with retinal vein occlusion and correlate with vitreal VEGF and the extent of macular edema
    • In press
    • Stahl A, Buchwald A, Martin G, et al. Vitreal levels of erythropoietin are increased in patients with retinal vein occlusion and correlate with vitreal VEGF and the extent of macular edema. Retina. In press.
    • Retina
    • Stahl, A.1    Buchwald, A.2    Martin, G.3
  • 113
    • 66349093990 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Ferrara N. Vascular endothelial growth factor. Arterioscler Thromb Vasc Biol. 2009;29:789-791.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 789-791
    • Ferrara, N.1
  • 114
    • 0041743158 scopus 로고    scopus 로고
    • Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization
    • Kondo T, Vicent D, Suzuma K, et al. Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. J Clin Invest. 2003;111:1835-1842.
    • (2003) J Clin Invest , vol.111 , pp. 1835-1842
    • Kondo, T.1    Vicent, D.2    Suzuma, K.3
  • 115
    • 0242300678 scopus 로고    scopus 로고
    • Postnatal serum insulinlike growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth
    • Hellstrom A, Engstrom E, Hard AL, et al. Postnatal serum insulinlike growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth. Pediatrics. 2003;112:1016-1020.
    • (2003) Pediatrics , vol.112 , pp. 1016-1020
    • Hellstrom, A.1    Engstrom, E.2    Hard, A.L.3
  • 116
    • 14344279279 scopus 로고    scopus 로고
    • Low IGF-I suppresses VEGFsurvival signaling in retinal endothelial cells: Direct correlation with clinical retinopathy of prematurity
    • Hellstrom A, Perruzzi C, Ju M, et al. Low IGF-I suppresses VEGFsurvival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci U S A. 2001;98:5804-5808.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5804-5808
    • Hellstrom, A.1    Perruzzi, C.2    Ju, M.3
  • 117
    • 18444410241 scopus 로고    scopus 로고
    • IGF-I is critical for normal vascularization of the human retina
    • Hellstrom A, Carlsson B, Niklasson A, et al. IGF-I is critical for normal vascularization of the human retina. J Clin Endocrinol Metab. 2002;87:3413-3416.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3413-3416
    • Hellstrom, A.1    Carlsson, B.2    Niklasson, A.3
  • 118
    • 34547551937 scopus 로고    scopus 로고
    • IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth
    • Lofqvist C, Chen J, Connor KM, et al. IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth. Proc Natl Acad Sci U S A. 2007; 104:10589-10594.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10589-10594
    • Lofqvist, C.1    Chen, J.2    Connor, K.M.3
  • 119
    • 64049105381 scopus 로고    scopus 로고
    • Quantification and localization of the IGF/insulin system expression in retinal blood vessels and neurons during oxygen-induced retinopathy in mice
    • Lofqvist C, Willett KL, Aspegren O, et al. Quantification and localization of the IGF/insulin system expression in retinal blood vessels and neurons during oxygen-induced retinopathy in mice. Invest Ophthalmol Vis Sci. 2009;50:1831-1837.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1831-1837
    • Lofqvist, C.1    Willett, K.L.2    Aspegren, O.3
  • 120
    • 70350719504 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation
    • Kielczewski JL, Jarajapu YP, McFarland EL, et al. Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res. 2009;105:897-905.
    • (2009) Circ Res , vol.105 , pp. 897-905
    • Kielczewski, J.L.1    Jarajapu, Y.P.2    McFarland, E.L.3
  • 121
    • 69049098085 scopus 로고    scopus 로고
    • A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGFbinding protein-3 complex to preterm infants
    • Lofqvist C, Niklasson A, Engstrom E, et al. A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGFbinding protein-3 complex to preterm infants. Pediatr Res. 2009; 65:574-579.
    • (2009) Pediatr Res , vol.65 , pp. 574-579
    • Lofqvist, C.1    Niklasson, A.2    Engstrom, E.3
  • 122
    • 34547552852 scopus 로고    scopus 로고
    • IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development
    • Chang KH, Chan-Ling T, McFarland EL, et al. IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development. Proc Natl Acad Sci U S A. 2007;104:10595-10600.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10595-10600
    • Chang, K.H.1    Chan-Ling, T.2    McFarland, E.L.3
  • 123
    • 0036281597 scopus 로고    scopus 로고
    • Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization
    • Grant MB, May WS, Caballero S, et al. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nat Med. 2002;8:607-612.
    • (2002) Nat Med , vol.8 , pp. 607-612
    • Grant, M.B.1    May, W.S.2    Caballero, S.3
  • 125
    • 8844256502 scopus 로고    scopus 로고
    • The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina
    • SanGiovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res. 2005;24:87-138.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 87-138
    • Sangiovanni, J.P.1    Chew, E.Y.2
  • 126
    • 0030856729 scopus 로고    scopus 로고
    • Are deficits of arachidonic and docosahexaenoic acids responsible for the neural and vascular complications of preterm babies?
    • Crawford MA, Costeloe K, Ghebremeskel K, Phylactos A, Skirvin L, Stacey F. Are deficits of arachidonic and docosahexaenoic acids responsible for the neural and vascular complications of preterm babies? Am J Clin Nutr. 1997;66:1032S-1041S.
    • (1997) Am J Clin Nutr , vol.66
    • Crawford, M.A.1    Costeloe, K.2    Ghebremeskel, K.3    Phylactos, A.4    Skirvin, L.5    Stacey, F.6
  • 127
    • 34447119437 scopus 로고    scopus 로고
    • Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis
    • Connor KM, SanGiovanni JP, Lofqvist C, et al. Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis. Nat Med. 2007;13:868-873.
    • (2007) Nat Med , vol.13 , pp. 868-873
    • Connor, K.M.1    Sangiovanni, J.P.2    Lofqvist, C.3
  • 128
    • 0038447915 scopus 로고    scopus 로고
    • Cyclooxygenase- 2 in human and experimental ischemic proliferative retinopathy
    • Sennlaub F, Valamanesh F, Vazquez-Tello A, et al. Cyclooxygenase- 2 in human and experimental ischemic proliferative retinopathy. Circulation. 2003;108:198-204.
    • (2003) Circulation , vol.108 , pp. 198-204
    • Sennlaub, F.1    Valamanesh, F.2    Vazquez-Tello, A.3
  • 129
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan CN, Hong S, Gronert K, et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med. 2002;196:1025-1037.
    • (2002) J Exp Med , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3
  • 130
    • 0021449829 scopus 로고
    • The negative coincidence of retinitis pigmentosa and proliferative diabetic retinopathy
    • Sternberg P Jr, Landers MB 3rd, Wolbarsht M. The negative coincidence of retinitis pigmentosa and proliferative diabetic retinopathy. Am J Ophthalmol. 1984;97:788-789.
    • (1984) Am J Ophthalmol , vol.97 , pp. 788-789
    • Sternberg Jr., P.1    Landers, M.B.2    Wolbarsht, M.3
  • 132
    • 0035964261 scopus 로고    scopus 로고
    • An antiangiogenic state in mice and humans with retinal photoreceptor cell degeneration
    • Lahdenranta J, Pasqualini R, Schlingemann RO, et al. An antiangiogenic state in mice and humans with retinal photoreceptor cell degeneration. Proc Natl Acad Sci U S A. 2001;98:10368-10373.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10368-10373
    • Lahdenranta, J.1    Pasqualini, R.2    Schlingemann, R.O.3
  • 133
    • 0033823838 scopus 로고    scopus 로고
    • Metabolic dependence of photoreceptors on the choroid in the normal and detached retina
    • Linsenmeier RA, Padnick-Silver L. Metabolic dependence of photoreceptors on the choroid in the normal and detached retina. Invest Ophthalmol Vis Sci. 2000;41:3117-3123.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3117-3123
    • Linsenmeier, R.A.1    Padnick-Silver, L.2
  • 134
    • 0033753749 scopus 로고    scopus 로고
    • Intraretinal oxygen levels before and after photoreceptor loss in the RCS rat
    • Yu DY, Cringle SJ, Su EN, Yu PK. Intraretinal oxygen levels before and after photoreceptor loss in the RCS rat. Invest Ophthalmol Vis Sci. 2000;41:3999-4006.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3999-4006
    • Yu, D.Y.1    Cringle, S.J.2    Su, E.N.3    Yu, P.K.4
  • 135
    • 0033759858 scopus 로고    scopus 로고
    • Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa
    • Penn JS, Li S, Naash MI. Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2000;41:4007-4013.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 4007-4013
    • Penn, J.S.1    Li, S.2    Naash, M.I.3
  • 137
    • 34248214623 scopus 로고    scopus 로고
    • Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia- regulated gene expression
    • de Gooyer TE, Stevenson KA, Humphries P, et al. Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia- regulated gene expression. Invest Ophthalmol Vis Sci.2006;47:5553-5560.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 5553-5560
    • de Gooyer, T.E.1    Stevenson, K.A.2    Humphries, P.3
  • 138
    • 35148835128 scopus 로고    scopus 로고
    • Rod photoreceptor function predicts blood vessel abnormality in retinopathy of prematurity
    • Akula JD, Hansen RM, Martinez-Perez ME, Fulton AB. Rod photoreceptor function predicts blood vessel abnormality in retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2007;48:4351-4359.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4351-4359
    • Akula, J.D.1    Hansen, R.M.2    Martinez-Perez, M.E.3    Fulton, A.B.4
  • 139
    • 34548783448 scopus 로고    scopus 로고
    • Neuronal and glial cell changes are determined by retinal vascularization in retinopathy of prematurity
    • Downie LE, Pianta MJ, Vingrys AJ, Wilkinson-Berka JL, Fletcher EL. Neuronal and glial cell changes are determined by retinal vascularization in retinopathy of prematurity. J Comp Neurol. 2007;504:404-417.
    • (2007) J Comp Neurol , vol.504 , pp. 404-417
    • Downie, L.E.1    Pianta, M.J.2    Vingrys, A.J.3    Wilkinson-Berka, J.L.4    Fletcher, E.L.5
  • 140
    • 0030448313 scopus 로고    scopus 로고
    • PDGF mediates a neuron-astrocyte interaction in the developing retina
    • Fruttiger M, Calver AR, Kruger WH, et al. PDGF mediates a neuron-astrocyte interaction in the developing retina. Neuron. 1996;17:1117-1131.
    • (1996) Neuron , vol.17 , pp. 1117-1131
    • Fruttiger, M.1    Calver, A.R.2    Kruger, W.H.3
  • 141
    • 0030668663 scopus 로고    scopus 로고
    • Development of the human retinal vasculature: Cellular relations and VEGF expression
    • Provis JM, Leech J, Diaz CM, Penfold PL, Stone J, Keshet E. Development of the human retinal vasculature: cellular relations and VEGF expression. Exp Eye Res. 1997;65:555-568.
    • (1997) Exp Eye Res , vol.65 , pp. 555-568
    • Provis, J.M.1    Leech, J.2    Diaz, C.M.3    Penfold, P.L.4    Stone, J.5    Keshet, E.6
  • 142
    • 0030774945 scopus 로고    scopus 로고
    • Role of astrocytes in the control of developing retinal vessels
    • Zhang Y, Stone J. Role of astrocytes in the control of developing retinal vessels. Invest Ophthalmol Vis Sci. 1997;38:1653-1666.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 1653-1666
    • Zhang, Y.1    Stone, J.2
  • 143
    • 0036847476 scopus 로고    scopus 로고
    • Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion
    • Dorrell MI, Aguilar E, Friedlander M. Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion. Invest Ophthalmol Vis Sci. 2002;43:3500-3510.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3500-3510
    • Dorrell, M.I.1    Aguilar, E.2    Friedlander, M.3
  • 144
    • 18844424905 scopus 로고    scopus 로고
    • Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes
    • West H, Richardson WD, Fruttiger M. Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes. Development. 2005;132:1855-1862.
    • (2005) Development , vol.132 , pp. 1855-1862
    • West, H.1    Richardson, W.D.2    Fruttiger, M.3
  • 145
    • 70549094339 scopus 로고    scopus 로고
    • Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy
    • Dorrell MI, Aguilar E, Jacobson R, et al. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy. Glia. 2010;58: 43-54.
    • (2010) Glia , vol.58 , pp. 43-54
    • Dorrell, M.I.1    Aguilar, E.2    Jacobson, R.3
  • 146
    • 53549118277 scopus 로고    scopus 로고
    • The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
    • Sapieha P, Sirinyan M, Hamel D, et al. The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis. Nat Med. 2008;14:1067-1076.
    • (2008) Nat Med , vol.14 , pp. 1067-1076
    • Sapieha, P.1    Sirinyan, M.2    Hamel, D.3
  • 147
    • 0029761062 scopus 로고    scopus 로고
    • A mouse model of diabetic retinopathy
    • Kern TS, Engerman RL. A mouse model of diabetic retinopathy. Arch Ophthalmol. 1996;114:986-990.
    • (1996) Arch Ophthalmol , vol.114 , pp. 986-990
    • Kern, T.S.1    Engerman, R.L.2
  • 148
    • 33644689817 scopus 로고    scopus 로고
    • Vascular damage in a mouse model of diabetic retinopathy: Relation to neuronal and glial changes
    • Feit-Leichman RA, Kinouchi R, Takeda M, et al. Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes. Invest Ophthalmol Vis Sci. 2005;46:4281-4287.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4281-4287
    • Feit-Leichman, R.A.1    Kinouchi, R.2    Takeda, M.3
  • 149
    • 7044228789 scopus 로고    scopus 로고
    • A central role for inflammation in the pathogenesis of diabetic retinopathy
    • Joussen AM, Poulaki V, Le ML, et al. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J. 2004; 18:1450-1452.
    • (2004) FASEB J , vol.18 , pp. 1450-1452
    • Joussen, A.M.1    Poulaki, V.2    Le, M.L.3
  • 150
    • 34547674399 scopus 로고    scopus 로고
    • Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes
    • Zheng L, Du Y, Miller C, et al. Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes. Diabetologia. 2007;50:1987-1996.
    • (2007) Diabetologia , vol.50 , pp. 1987-1996
    • Zheng, L.1    Du, Y.2    Miller, C.3
  • 152
    • 34250723764 scopus 로고    scopus 로고
    • Incipient diabetic retinopathy: Insights from an experimental model
    • Feng Y, vom Hagen F, Lin J, Hammes HP. Incipient diabetic retinopathy: insights from an experimental model. Ophthalmologica. 2007;221:269-274.
    • (2007) Ophthalmologica , vol.221 , pp. 269-274
    • Feng, Y.1    vom Hagen, F.2    Lin, J.3    Hammes, H.P.4
  • 153
    • 51849157860 scopus 로고    scopus 로고
    • Retinal ganglion cells in diabetes
    • Kern TS, Barber AJ. Retinal ganglion cells in diabetes. J Physiol. 2008;586:4401-4408.
    • (2008) J Physiol , vol.586 , pp. 4401-4408
    • Kern, T.S.1    Barber, A.J.2
  • 154
    • 63849118178 scopus 로고    scopus 로고
    • Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy
    • Zheng L, Kern TS. Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy. Front Biosci. 2009;14:3974-3987.
    • (2009) Front Biosci , vol.14 , pp. 3974-3987
    • Zheng, L.1    Kern, T.S.2
  • 155
    • 17844364194 scopus 로고    scopus 로고
    • New insights into the retinal circulation: Inflammatory lipid mediators in ischemic retinopathy
    • Hardy P, Beauchamp M, Sennlaub F, et al. New insights into the retinal circulation: inflammatory lipid mediators in ischemic retinopathy. Prostaglandins Leukot Essent Fatty Acids. 2005;72: 301-325.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.72 , pp. 301-325
    • Hardy, P.1    Beauchamp, M.2    Sennlaub, F.3
  • 157
    • 11144236527 scopus 로고    scopus 로고
    • Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygeninduced retinopathy
    • Zhang SX, Ma JX, Sima J, et al. Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygeninduced retinopathy. Am J Pathol. 2005;166:313-321.
    • (2005) Am J Pathol , vol.166 , pp. 313-321
    • Zhang, S.X.1    Ma, J.X.2    Sima, J.3
  • 158
    • 77952534629 scopus 로고    scopus 로고
    • The significance of neuronal and glial cell changes in the rat retina during oxygeninduced retinopathy
    • Fletcher EL, Downie LE, Hatzopoulos K, et al. The significance of neuronal and glial cell changes in the rat retina during oxygeninduced retinopathy. Doc Ophthalmol. 2010;120:67-86.
    • (2010) Doc Ophthalmol , vol.120 , pp. 67-86
    • Fletcher, E.L.1    Downie, L.E.2    Hatzopoulos, K.3
  • 159
    • 13744249120 scopus 로고    scopus 로고
    • Nonproliferative retinopathy in diabetes type 2. Initial stages and characterization of phenotypes
    • Cunha-Vaz J, Bernardes R. Nonproliferative retinopathy in diabetes type 2. Initial stages and characterization of phenotypes. Prog Retin Eye Res. 2005;24:355-377.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 355-377
    • Cunha-Vaz, J.1    Bernardes, R.2
  • 160
    • 0031038075 scopus 로고    scopus 로고
    • Upregulation of vascular endothelial growth factor in ischemic and non-ischemic human and experimental retinal disease
    • Vinores SA, Youssri AI, Luna JD, et al. Upregulation of vascular endothelial growth factor in ischemic and non-ischemic human and experimental retinal disease. Histol Histopathol. 1997;12: 99-109.
    • (1997) Histol Histopathol , vol.12 , pp. 99-109
    • Vinores, S.A.1    Youssri, A.I.2    Luna, J.D.3
  • 161
    • 0034854865 scopus 로고    scopus 로고
    • VEGF-initiated blood-retinal barrier breakdown in early diabetes
    • Qaum T, Xu Q, Joussen AM, et al. VEGF-initiated blood-retinal barrier breakdown in early diabetes. Invest Ophthalmol Vis Sci. 2001;42:2408-2413.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2408-2413
    • Qaum, T.1    Xu, Q.2    Joussen, A.M.3
  • 162
    • 0346777254 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives
    • Caldwell RB, Bartoli M, Behzadian MA, et al. Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives. Diabetes Metab Res Rev. 2003;19:442-455.
    • (2003) Diabetes Metab Res Rev , vol.19 , pp. 442-455
    • Caldwell, R.B.1    Bartoli, M.2    Behzadian, M.A.3
  • 163
    • 0030832082 scopus 로고    scopus 로고
    • Growth factors in age-related macular degeneration: Pathogenic and therapeutic implications
    • Frank RN. Growth factors in age-related macular degeneration: pathogenic and therapeutic implications. Ophthalmic Res. 1997; 29:341-353.
    • (1997) Ophthalmic Res , vol.29 , pp. 341-353
    • Frank, R.N.1
  • 164
    • 20144387561 scopus 로고    scopus 로고
    • Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey
    • Husain D, Kim I, Gauthier D, et al. Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey. Arch Ophthalmol. 2005;123:509-516.
    • (2005) Arch Ophthalmol , vol.123 , pp. 509-516
    • Husain, D.1    Kim, I.2    Gauthier, D.3
  • 165
    • 0018653493 scopus 로고
    • The development of an experimental model of subretinal neovascularization in disciform macular degeneration
    • Ryan SJ. The development of an experimental model of subretinal neovascularization in disciform macular degeneration. Trans Am Ophthalmol Soc. 1979;77:707-745.
    • (1979) Trans Am Ophthalmol Soc , vol.77 , pp. 707-745
    • Ryan, S.J.1
  • 167
    • 0037401890 scopus 로고    scopus 로고
    • VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier
    • Saishin Y, Saishin Y, Takahashi K, et al. VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J Cell Physiol. 2003;195:241-248.
    • (2003) J Cell Physiol , vol.195 , pp. 241-248
    • Saishin, Y.1    Saishin, Y.2    Takahashi, K.3
  • 168
    • 33644653277 scopus 로고    scopus 로고
    • Hematopoietic stem cells provide repair functions after laser-induced Bruch's membrane rupture model of choroidal neovascularization
    • Chan-Ling T, Baxter L, Afzal A, et al. Hematopoietic stem cells provide repair functions after laser-induced Bruch's membrane rupture model of choroidal neovascularization. Am J Pathol. 2006;168:1031-1044.
    • (2006) Am J Pathol , vol.168 , pp. 1031-1044
    • Chan-Ling, T.1    Baxter, L.2    Afzal, A.3
  • 171
    • 11144251226 scopus 로고    scopus 로고
    • Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors
    • Sengupta N, Caballero S, Mames RN, Timmers AM, Saban D, Grant MB. Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors. Invest Ophthalmol Vis Sci. 2005;46:343-348.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 343-348
    • Sengupta, N.1    Caballero, S.2    Mames, R.N.3    Timmers, A.M.4    Saban, D.5    Grant, M.B.6
  • 172
    • 68549125419 scopus 로고    scopus 로고
    • Genetic loci that control the size of laser-induced choroidal neovascularization
    • Nakai K, Rogers MS, Baba T, et al. Genetic loci that control the size of laser-induced choroidal neovascularization. FASEB J. 2009; 23:2235-2243.
    • (2009) FASEB J , vol.23 , pp. 2235-2243
    • Nakai, K.1    Rogers, M.S.2    Baba, T.3
  • 174
    • 0038147049 scopus 로고    scopus 로고
    • Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization
    • Sakurai E, Taguchi H, Anand A, et al. Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003;44:2743-2749.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 2743-2749
    • Sakurai, E.1    Taguchi, H.2    Anand, A.3
  • 175
    • 33144488589 scopus 로고    scopus 로고
    • Drusen complement components C3a and C5a promote choroidal neovascularization
    • Nozaki M, Raisler BJ, Sakurai E, et al. Drusen complement components C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci U S A. 2006;103:2328-2333.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2328-2333
    • Nozaki, M.1    Raisler, B.J.2    Sakurai, E.3
  • 176
    • 67650457597 scopus 로고    scopus 로고
    • CCR3 is a target for age-related macular degeneration diagnosis and therapy
    • Takeda A, Baffi JZ, Kleinman ME, et al. CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature. 2009;460:225-230.
    • (2009) Nature , vol.460 , pp. 225-230
    • Takeda, A.1    Baffi, J.Z.2    Kleinman, M.E.3
  • 177
    • 0344676389 scopus 로고    scopus 로고
    • An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2- deficient mice
    • Ambati J, Anand A, Fernandez S, et al. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2- deficient mice. Nat Med. 2003;9:1390-1397.
    • (2003) Nat Med , vol.9 , pp. 1390-1397
    • Ambati, J.1    Anand, A.2    Fernandez, S.3
  • 178
    • 34948898131 scopus 로고    scopus 로고
    • CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration
    • Combadiere C, Feumi C, Raoul W, et al. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest. 2007; 117:2920-2928.
    • (2007) J Clin Invest , vol.117 , pp. 2920-2928
    • Combadiere, C.1    Feumi, C.2    Raoul, W.3
  • 179
    • 34648846532 scopus 로고    scopus 로고
    • Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration
    • Tuo J, Bojanowski CM, Zhou M, et al. Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. Invest Ophthalmol Vis Sci. 2007;48:3827-3836.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 3827-3836
    • Tuo, J.1    Bojanowski, C.M.2    Zhou, M.3
  • 180
    • 68449094580 scopus 로고    scopus 로고
    • A high omega-3 fatty acid diet reduces retinal lesions in a murine model of macular degeneration
    • Tuo J, Ross RJ, Herzlich AA, et al. A high omega-3 fatty acid diet reduces retinal lesions in a murine model of macular degeneration. Am J Pathol. 2009;175:799-807.
    • (2009) Am J Pathol , vol.175 , pp. 799-807
    • Tuo, J.1    Ross, R.J.2    Herzlich, A.A.3
  • 181
    • 72749091971 scopus 로고    scopus 로고
    • ω-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: A prospective cohort study from the Age-Related Eye Disease Study
    • Sangiovanni JP, Agron E, Meleth AD, et al. ω-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2009;90:1601-1607.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1601-1607
    • Sangiovanni, J.P.1    Agron, E.2    Meleth, A.D.3
  • 182
    • 45749143528 scopus 로고    scopus 로고
    • Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits
    • Scheppke L, Aguilar E, Gariano RF, et al. Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits. J Clin Invest. 2008;118: 2337-2346.
    • (2008) J Clin Invest , vol.118 , pp. 2337-2346
    • Scheppke, L.1    Aguilar, E.2    Gariano, R.F.3
  • 183
    • 13144267708 scopus 로고    scopus 로고
    • Functions of the two glutamate transporters GLAST and GLT-1 in the retina
    • Harada T, Harada C, Watanabe M, et al. Functions of the two glutamate transporters GLAST and GLT-1 in the retina. Proc Natl Acad Sci U S A. 1998;95:4663-4666.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4663-4666
    • Harada, T.1    Harada, C.2    Watanabe, M.3
  • 184
    • 33846916279 scopus 로고    scopus 로고
    • Retinal ischemia and reperfusion causes capillary degeneration: Similarities to diabetes
    • Zheng L, Gong B, Hatala DA, Kern TS. Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes. Invest Ophthalmol Vis Sci. 2007;48:361-367.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 361-367
    • Zheng, L.1    Gong, B.2    Hatala, D.A.3    Kern, T.S.4
  • 185
    • 34047144378 scopus 로고    scopus 로고
    • Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells
    • Caballero S, Sengupta N, Afzal A, et al. Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes. 2007;56:960-967.
    • (2007) Diabetes , vol.56 , pp. 960-967
    • Caballero, S.1    Sengupta, N.2    Afzal, A.3
  • 186
    • 66149139466 scopus 로고    scopus 로고
    • Review of anti-VEGF therapy in proliferative diabetic retinopathy
    • Jardeleza MS, Miller JW. Review of anti-VEGF therapy in proliferative diabetic retinopathy. Semin Ophthalmol. 2009;24:87-92.
    • (2009) Semin Ophthalmol , vol.24 , pp. 87-92
    • Jardeleza, M.S.1    Miller, J.W.2
  • 187
    • 0030844479 scopus 로고    scopus 로고
    • Transgenic mice with increased expression of vascular endothelial growth factor in the retina: A new model of intraretinal and subretinal neovascularization
    • Okamoto N, Tobe T, Hackett SF, et al. Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization. Am J Pathol. 1997;151:281-291.
    • (1997) Am J Pathol , vol.151 , pp. 281-291
    • Okamoto, N.1    Tobe, T.2    Hackett, S.F.3
  • 188
    • 0031975156 scopus 로고    scopus 로고
    • Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors
    • Tobe T, Okamoto N, Vinores MA, et al. Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors. Invest Ophthalmol Vis Sci. 1998;39:180-188.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 180-188
    • Tobe, T.1    Okamoto, N.2    Vinores, M.A.3
  • 189
    • 0036168483 scopus 로고    scopus 로고
    • Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment
    • Ohno-Matsui K, Hirose A, Yamamoto S, et al. Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment. Am J Pathol. 2002;160:711-719.
    • (2002) Am J Pathol , vol.160 , pp. 711-719
    • Ohno-Matsui, K.1    Hirose, A.2    Yamamoto, S.3
  • 190
    • 11144354304 scopus 로고    scopus 로고
    • Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease
    • Ruberte J, Ayuso E, Navarro M, et al. Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease. J Clin Invest. 2004;113:1149-1157.
    • (2004) J Clin Invest , vol.113 , pp. 1149-1157
    • Ruberte, J.1    Ayuso, E.2    Navarro, M.3


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