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Volumn 116, Issue , 2013, Pages 177-184

Retinal pigment epithelium cells produce VEGF in response to oxidized phospholipids through mechanisms involving ATF4 and protein kinase CK2

Author keywords

Angiogenesis; Oxidized phospholipids; Protein kinase CK2; RPE; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASEIN KINASE II; MESSENGER RNA; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; SMALL INTERFERING RNA; VASCULOTROPIN;

EID: 84884725047     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2013.08.021     Document Type: Article
Times cited : (27)

References (32)
  • 1
    • 0027225863 scopus 로고
    • Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells
    • Adamis A.P., Shima D.T., Yeo K.T., Yeo T.K., Brown L.F., Berse B., D'Amore P.A., Folkman J. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem. Biophys. Res. Comm. 1993, 193:631-638.
    • (1993) Biochem. Biophys. Res. Comm. , vol.193 , pp. 631-638
    • Adamis, A.P.1    Shima, D.T.2    Yeo, K.T.3    Yeo, T.K.4    Brown, L.F.5    Berse, B.6    D'Amore, P.A.7    Folkman, J.8
  • 2
    • 78650903532 scopus 로고    scopus 로고
    • Involvement of CK2 in activation of electrophilic genes in endothelial cells by oxidized phospholipids
    • Afonyushkin T., Oskolkova O.V., Binder B.R., Bochkov V.N. Involvement of CK2 in activation of electrophilic genes in endothelial cells by oxidized phospholipids. J.Lipid Res. 2011, 52:98-103.
    • (2011) J.Lipid Res. , vol.52 , pp. 98-103
    • Afonyushkin, T.1    Oskolkova, O.V.2    Binder, B.R.3    Bochkov, V.N.4
  • 3
    • 77951479702 scopus 로고    scopus 로고
    • Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways
    • Afonyushkin T., Oskolkova O.V., Philippova M., Resink T.J., Erne P., Binder B.R., Bochkov V.N. Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways. Arterioscler. Thromb. Vasc. Biol. 2010, 30:1007-1013.
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 1007-1013
    • Afonyushkin, T.1    Oskolkova, O.V.2    Philippova, M.3    Resink, T.J.4    Erne, P.5    Binder, B.R.6    Bochkov, V.N.7
  • 4
    • 0036568813 scopus 로고    scopus 로고
    • Joining the cell survival squad: an emerging role for protein kinase CK2
    • Ahmed K., Gerber D.A., Cochet C. Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol. 2002, 12:226-230.
    • (2002) Trends Cell Biol. , vol.12 , pp. 226-230
    • Ahmed, K.1    Gerber, D.A.2    Cochet, C.3
  • 5
    • 0347651828 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution
    • Becerra S.P., Fariss R.N., Wu Y.Q., Montuenga L.M., Wong P., Pfeffer B.A. Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution. Exp. Eye Res. 2004, 78:223-234.
    • (2004) Exp. Eye Res. , vol.78 , pp. 223-234
    • Becerra, S.P.1    Fariss, R.N.2    Wu, Y.Q.3    Montuenga, L.M.4    Wong, P.5    Pfeffer, B.A.6
  • 6
    • 0032807809 scopus 로고    scopus 로고
    • Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation
    • Blaauwgeers H.G., Holtkamp G.M., Rutten H., Witmer A.N., Koolwijk P., Partanen T.A., Alitalo K., Kroon M.E., Kijlstra A., van Hinsbergh V.W., Schlingemann R.O. Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation. Am. J. Pathol. 1999, 155:421-428.
    • (1999) Am. J. Pathol. , vol.155 , pp. 421-428
    • Blaauwgeers, H.G.1    Holtkamp, G.M.2    Rutten, H.3    Witmer, A.N.4    Koolwijk, P.5    Partanen, T.A.6    Alitalo, K.7    Kroon, M.E.8    Kijlstra, A.9    van Hinsbergh, V.W.10    Schlingemann, R.O.11
  • 9
    • 0014402405 scopus 로고
    • Phospholipids in tissues of the eye. I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids
    • Broekhuyse R.M. Phospholipids in tissues of the eye. I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids. Biochem. Biophys. Acta 1968, 152:307-315.
    • (1968) Biochem. Biophys. Acta , vol.152 , pp. 307-315
    • Broekhuyse, R.M.1
  • 10
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • de Jong P.T. Age-related macular degeneration. N.Engl. J. Med. 2006, 355:1474-1485.
    • (2006) N.Engl. J. Med. , vol.355 , pp. 1474-1485
    • de Jong, P.T.1
  • 11
    • 70649094281 scopus 로고    scopus 로고
    • Neovascular age-related macular degeneration: intraocular cytokines and growth factors and the influence of therapy with ranibizumab
    • Funk M., Karl D., Georgopoulos M., Benesch T., Sacu S., Polak K., Zlabinger G.J., Schmidt-Erfurth U. Neovascular age-related macular degeneration: intraocular cytokines and growth factors and the influence of therapy with ranibizumab. Ophthalmology 2009, 116:2393-2399.
    • (2009) Ophthalmology , vol.116 , pp. 2393-2399
    • Funk, M.1    Karl, D.2    Georgopoulos, M.3    Benesch, T.4    Sacu, S.5    Polak, K.6    Zlabinger, G.J.7    Schmidt-Erfurth, U.8
  • 17
    • 0029879849 scopus 로고    scopus 로고
    • Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes
    • Lopez P.F., Sippy B.D., Lambert H.M., Thach A.B., Hinton D.R. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Invest. Ophthalmol. Vis. Sci. 1996, 37:855-868.
    • (1996) Invest. Ophthalmol. Vis. Sci. , vol.37 , pp. 855-868
    • Lopez, P.F.1    Sippy, B.D.2    Lambert, H.M.3    Thach, A.B.4    Hinton, D.R.5
  • 20
    • 79958786721 scopus 로고    scopus 로고
    • Asystematic review of the efficacy and safety outcomes of anti-VEGF agents used for treating neovascular age-related macular degeneration: comparison of ranibizumab and bevacizumab
    • Mitchell P. Asystematic review of the efficacy and safety outcomes of anti-VEGF agents used for treating neovascular age-related macular degeneration: comparison of ranibizumab and bevacizumab. Curr. Med. Res. Opin. 2011, 27:1465-1475.
    • (2011) Curr. Med. Res. Opin. , vol.27 , pp. 1465-1475
    • Mitchell, P.1
  • 21
    • 78449240947 scopus 로고    scopus 로고
    • Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation
    • Niture S.K., Jaiswal A.K. Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation. J.Biol. Chem. 2010, 19:36865-36875.
    • (2010) J.Biol. Chem. , vol.19 , pp. 36865-36875
    • Niture, S.K.1    Jaiswal, A.K.2
  • 22
    • 47649102147 scopus 로고    scopus 로고
    • ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response
    • Oskolkova O.V., Afonyushkin T., Leitner A., von Schlieffen E., Gargalovic P.S., Lusis A.J., Binder B.R., Bochkov V.N. ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response. Blood 2008, 112:330-339.
    • (2008) Blood , vol.112 , pp. 330-339
    • Oskolkova, O.V.1    Afonyushkin, T.2    Leitner, A.3    von Schlieffen, E.4    Gargalovic, P.S.5    Lusis, A.J.6    Binder, B.R.7    Bochkov, V.N.8
  • 26
    • 20144378800 scopus 로고    scopus 로고
    • The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism
    • Roybal C.N., Hunsaker L.A., Barbash O., Vander Jagt D.L., Abcouwer S.F. The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism. J.Biol. Chem. 2005, 280:20331-20339.
    • (2005) J.Biol. Chem. , vol.280 , pp. 20331-20339
    • Roybal, C.N.1    Hunsaker, L.A.2    Barbash, O.3    Vander Jagt, D.L.4    Abcouwer, S.F.5
  • 27
    • 2442572249 scopus 로고    scopus 로고
    • Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4
    • Roybal C.N., Yang S., Sun C.W., Hurtado D., Vander Jagt D.L., Townes T.M., Abcouwer S.F. Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. J.Biol. Chem. 2004, 279:14844-14852.
    • (2004) J.Biol. Chem. , vol.279 , pp. 14844-14852
    • Roybal, C.N.1    Yang, S.2    Sun, C.W.3    Hurtado, D.4    Vander Jagt, D.L.5    Townes, T.M.6    Abcouwer, S.F.7
  • 28
    • 34249802348 scopus 로고    scopus 로고
    • Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration
    • Suzuki M., Kamei M., Itabe H., Yoneda K., Bando H., Kume N., Tano Y. Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration. Mol. Vis. 2007, 13:772-778.
    • (2007) Mol. Vis. , vol.13 , pp. 772-778
    • Suzuki, M.1    Kamei, M.2    Itabe, H.3    Yoneda, K.4    Bando, H.5    Kume, N.6    Tano, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.