-
1
-
-
84855484381
-
Evolutionary genetic dissection of human interferons
-
Manry J., et al. Evolutionary genetic dissection of human interferons. J. Exp. Med. 2011, 208:2747-2759.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2747-2759
-
-
Manry, J.1
-
2
-
-
80052164116
-
Cytoplasmic DNA innate immune pathways
-
Barber G.N. Cytoplasmic DNA innate immune pathways. Immunol. Rev. 2011, 243:99-108.
-
(2011)
Immunol. Rev.
, vol.243
, pp. 99-108
-
-
Barber, G.N.1
-
3
-
-
84872259257
-
A virological view of innate immune recognition
-
Iwasaki A. A virological view of innate immune recognition. Annu. Rev. Microbiol. 2012, 66:177-196.
-
(2012)
Annu. Rev. Microbiol.
, vol.66
, pp. 177-196
-
-
Iwasaki, A.1
-
4
-
-
84896958063
-
Innate immune sensing and signaling of cytosolic nucleic acids
-
Wu J., Chen Z.J. Innate immune sensing and signaling of cytosolic nucleic acids. Annu. Rev. Immunol. 2014, 32:461-488.
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 461-488
-
-
Wu, J.1
Chen, Z.J.2
-
5
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun L., et al. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013, 339:786-791.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
-
6
-
-
0019739254
-
Production of interferon in human leukocytes from normal donors with the use of Sendai virus
-
Cantell K., et al. Production of interferon in human leukocytes from normal donors with the use of Sendai virus. Methods Enzymol. 1981, 78:29-38.
-
(1981)
Methods Enzymol.
, vol.78
, pp. 29-38
-
-
Cantell, K.1
-
7
-
-
0032582712
-
Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes
-
Au W.C., et al. Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes. J. Biol. Chem. 1998, 273:29210-29217.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29210-29217
-
-
Au, W.C.1
-
8
-
-
0035968246
-
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
-
Barnes B.J., et al. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J. Biol. Chem. 2001, 276:23382-23390.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23382-23390
-
-
Barnes, B.J.1
-
9
-
-
0032538891
-
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
-
Marie I., et al. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J. 1998, 17:6660-6669.
-
(1998)
EMBO J.
, vol.17
, pp. 6660-6669
-
-
Marie, I.1
-
10
-
-
23944516870
-
The host type I interferon response to viral and bacterial infections
-
Perry A.K., et al. The host type I interferon response to viral and bacterial infections. Cell Res. 2005, 15:407-422.
-
(2005)
Cell Res.
, vol.15
, pp. 407-422
-
-
Perry, A.K.1
-
11
-
-
84875642301
-
Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness
-
Hemont C., et al. Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness. J. Leukoc. Biol. 2013, 93:599-609.
-
(2013)
J. Leukoc. Biol.
, vol.93
, pp. 599-609
-
-
Hemont, C.1
-
12
-
-
84878232476
-
The history of Toll-like receptors - redefining innate immunity
-
O'Neill L.A., et al. The history of Toll-like receptors - redefining innate immunity. Nat. Rev. Immunol. 2013, 13:453-460.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 453-460
-
-
O'Neill, L.A.1
-
13
-
-
47249129985
-
Distinct signature type I interferon responses are determined by the infecting virus and the target cell
-
Baig E., Fish E.N. Distinct signature type I interferon responses are determined by the infecting virus and the target cell. Antivir. Ther. 2008, 13:409-422.
-
(2008)
Antivir. Ther.
, vol.13
, pp. 409-422
-
-
Baig, E.1
Fish, E.N.2
-
14
-
-
1642370060
-
Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells
-
Coccia E.M., et al. Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur. J. Immunol. 2004, 34:796-805.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 796-805
-
-
Coccia, E.M.1
-
15
-
-
77956626106
-
The early interferon alpha subtype response in infant macaques infected orally with SIV
-
Easlick J., et al. The early interferon alpha subtype response in infant macaques infected orally with SIV. J. Acquir. Immune Defic. Syndr. 2010, 55:14-28.
-
(2010)
J. Acquir. Immune Defic. Syndr.
, vol.55
, pp. 14-28
-
-
Easlick, J.1
-
16
-
-
67649185871
-
Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7
-
Genin P., et al. Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 2009, 29:3435-3450.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3435-3450
-
-
Genin, P.1
-
17
-
-
84866428295
-
Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent
-
Hillyer P., et al. Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent. Immunol. Cell Biol. 2012, 90:774-783.
-
(2012)
Immunol. Cell Biol.
, vol.90
, pp. 774-783
-
-
Hillyer, P.1
-
18
-
-
0021760405
-
Differential expression of human interferon genes
-
Hiscott J., et al. Differential expression of human interferon genes. Nucleic Acids Res. 1984, 12:3727-3746.
-
(1984)
Nucleic Acids Res.
, vol.12
, pp. 3727-3746
-
-
Hiscott, J.1
-
19
-
-
9144234252
-
Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells
-
Izaguirre A., et al. Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells. J. Leukoc. Biol. 2003, 74:1125-1138.
-
(2003)
J. Leukoc. Biol.
, vol.74
, pp. 1125-1138
-
-
Izaguirre, A.1
-
20
-
-
34547911079
-
Type I interferon subtypes produced by human peripheral mononuclear cells from one normal donor stimulated by viral and non-viral inducing factors
-
Palmer P., et al. Type I interferon subtypes produced by human peripheral mononuclear cells from one normal donor stimulated by viral and non-viral inducing factors. Eur. Cytokine Netw. 2007, 18:108-114.
-
(2007)
Eur. Cytokine Netw.
, vol.18
, pp. 108-114
-
-
Palmer, P.1
-
21
-
-
84855323411
-
TLR9 and TLR7 agonists mediate distinct type I IFN responses in humans and nonhuman primates in vitro and in vivo
-
Puig M., et al. TLR9 and TLR7 agonists mediate distinct type I IFN responses in humans and nonhuman primates in vitro and in vivo. J. Leukoc. Biol. 2012, 91:147-158.
-
(2012)
J. Leukoc. Biol.
, vol.91
, pp. 147-158
-
-
Puig, M.1
-
22
-
-
57149099467
-
Rigid interferon-alpha subtype responses of human plasmacytoid dendritic cells
-
Szubin R., et al. Rigid interferon-alpha subtype responses of human plasmacytoid dendritic cells. J. Interferon Cytokine Res. 2008, 28:749-763.
-
(2008)
J. Interferon Cytokine Res.
, vol.28
, pp. 749-763
-
-
Szubin, R.1
-
23
-
-
84906329921
-
Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens
-
Thomas J.M., et al. Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens. J. Virol. 2014, 88:10758-10766.
-
(2014)
J. Virol.
, vol.88
, pp. 10758-10766
-
-
Thomas, J.M.1
-
24
-
-
84873637980
-
Tissue-specific interferon alpha subtype response to SIV infection in brain, spleen, and lung
-
Zaritsky L.A., et al. Tissue-specific interferon alpha subtype response to SIV infection in brain, spleen, and lung. J. Interferon Cytokine Res. 2013, 33:24-33.
-
(2013)
J. Interferon Cytokine Res.
, vol.33
, pp. 24-33
-
-
Zaritsky, L.A.1
-
25
-
-
0033546053
-
The nature of the principal type 1 interferon-producing cells in human blood
-
Siegal F.P., et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 1999, 284:1835-1837.
-
(1999)
Science
, vol.284
, pp. 1835-1837
-
-
Siegal, F.P.1
-
26
-
-
15244349785
-
Plasmacytoid dendritic cells in immunity
-
Colonna M., et al. Plasmacytoid dendritic cells in immunity. Nat. Immunol. 2004, 5:1219-1226.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1219-1226
-
-
Colonna, M.1
-
27
-
-
84907033602
-
Independent of plasmacytoid dendritic cell (pDC) infection, pDC triggered by virus-infected cells mount enhanced type I IFN responses of different composition as opposed to pDC stimulated with free virus
-
Frenz T., et al. Independent of plasmacytoid dendritic cell (pDC) infection, pDC triggered by virus-infected cells mount enhanced type I IFN responses of different composition as opposed to pDC stimulated with free virus. J. Immunol. 2014, 193:2496-2503.
-
(2014)
J. Immunol.
, vol.193
, pp. 2496-2503
-
-
Frenz, T.1
-
28
-
-
0035955680
-
Interferon-kappa, a novel type I interferon expressed in human keratinocytes
-
LaFleur D.W., et al. Interferon-kappa, a novel type I interferon expressed in human keratinocytes. J. Biol. Chem. 2001, 276:39765-39771.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39765-39771
-
-
LaFleur, D.W.1
-
29
-
-
84874396777
-
Interferon-epsilon protects the female reproductive tract from viral and bacterial infection
-
Fung K.Y., et al. Interferon-epsilon protects the female reproductive tract from viral and bacterial infection. Science 2013, 339:1088-1092.
-
(2013)
Science
, vol.339
, pp. 1088-1092
-
-
Fung, K.Y.1
-
30
-
-
84867954482
-
Role of novel type I interferon epsilon in viral infection and mucosal immunity
-
Xi Y., et al. Role of novel type I interferon epsilon in viral infection and mucosal immunity. Mucosal Immunol. 2012, 5:610-622.
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 610-622
-
-
Xi, Y.1
-
31
-
-
84918829601
-
Unraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design
-
Wijesundara D.K., et al. Unraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design. Front. Immunol. 2014, 5:412.
-
(2014)
Front. Immunol.
, vol.5
, pp. 412
-
-
Wijesundara, D.K.1
-
32
-
-
79956353201
-
IFN-lambda determines the intestinal epithelial antiviral host defense
-
Pott J., et al. IFN-lambda determines the intestinal epithelial antiviral host defense. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:7944-7949.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 7944-7949
-
-
Pott, J.1
-
33
-
-
84901358668
-
Pathogenic potential of interferon alphabeta in acute influenza infection
-
Davidson S., et al. Pathogenic potential of interferon alphabeta in acute influenza infection. Nat. Commun. 2014, 5:3864.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3864
-
-
Davidson, S.1
-
34
-
-
84903779440
-
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections
-
Egli A., et al. The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Emerg. Microbes Infect. 2014, 3:e51.
-
(2014)
Emerg. Microbes Infect.
, vol.3
, pp. e51
-
-
Egli, A.1
-
35
-
-
0029052176
-
Ligand-induced association of the type I interferon receptor components
-
Cohen B., et al. Ligand-induced association of the type I interferon receptor components. Mol. Cell. Biol. 1995, 15:4208-4214.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4208-4214
-
-
Cohen, B.1
-
36
-
-
33846345778
-
Differential receptor subunit affinities of type I interferons govern differential signal activation
-
Jaks E., et al. Differential receptor subunit affinities of type I interferons govern differential signal activation. J. Mol. Biol. 2007, 366:525-539.
-
(2007)
J. Mol. Biol.
, vol.366
, pp. 525-539
-
-
Jaks, E.1
-
37
-
-
80053323418
-
Binding and activity of all human alpha interferon subtypes
-
Lavoie T.B., et al. Binding and activity of all human alpha interferon subtypes. Cytokine 2011, 56:282-289.
-
(2011)
Cytokine
, vol.56
, pp. 282-289
-
-
Lavoie, T.B.1
-
38
-
-
84867411811
-
Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation
-
Piehler J., et al. Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation. Immunol. Rev. 2012, 250:317-334.
-
(2012)
Immunol. Rev.
, vol.250
, pp. 317-334
-
-
Piehler, J.1
-
39
-
-
84895904323
-
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
-
Schoggins J.W., et al. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature 2014, 505:691-695.
-
(2014)
Nature
, vol.505
, pp. 691-695
-
-
Schoggins, J.W.1
-
40
-
-
79955542915
-
A diverse range of gene products are effectors of the type I interferon antiviral response
-
Schoggins J.W., et al. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 2011, 472:481-485.
-
(2011)
Nature
, vol.472
, pp. 481-485
-
-
Schoggins, J.W.1
-
41
-
-
79961163823
-
Stochastic receptor expression determines cell fate upon interferon treatment
-
Levin D., et al. Stochastic receptor expression determines cell fate upon interferon treatment. Mol. Cell. Biol. 2011, 31:3252-3266.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3252-3266
-
-
Levin, D.1
-
42
-
-
78349307010
-
The differential activity of interferon-alpha subtypes is consistent among distinct target genes and cell types
-
Moll H.P., et al. The differential activity of interferon-alpha subtypes is consistent among distinct target genes and cell types. Cytokine 2011, 53:52-59.
-
(2011)
Cytokine
, vol.53
, pp. 52-59
-
-
Moll, H.P.1
-
43
-
-
80051983083
-
Structural linkage between ligand discrimination and receptor activation by type I interferons
-
Thomas C., et al. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell 2011, 146:621-632.
-
(2011)
Cell
, vol.146
, pp. 621-632
-
-
Thomas, C.1
-
44
-
-
84901945177
-
Multifaceted activities of type I interferon are revealed by a receptor antagonist
-
Levin D., et al. Multifaceted activities of type I interferon are revealed by a receptor antagonist. Sci. Signal. 2014, 7:ra50.
-
(2014)
Sci. Signal.
, vol.7
, pp. ra50
-
-
Levin, D.1
-
45
-
-
68849114353
-
Receptor density is key to the alpha2/beta interferon differential activities
-
Moraga I., et al. Receptor density is key to the alpha2/beta interferon differential activities. Mol. Cell. Biol. 2009, 29:4778-4787.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4778-4787
-
-
Moraga, I.1
-
46
-
-
84866175713
-
Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection
-
Gibbert K., et al. Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection. PLoS Pathog. 2012, 8:e1002868.
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1002868
-
-
Gibbert, K.1
-
47
-
-
33745626171
-
Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors
-
Marchetti M., et al. Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors. Mol. Biol. Cell 2006, 17:2896-2909.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2896-2909
-
-
Marchetti, M.1
-
48
-
-
0020403301
-
Down-regulation of the interferon receptor
-
Branca A.A., Baglioni C. Down-regulation of the interferon receptor. J. Biol. Chem. 1982, 257:13197-13200.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13197-13200
-
-
Branca, A.A.1
Baglioni, C.2
-
49
-
-
77649319880
-
Biochemical monitoring of the early endocytic traffic of the type I interferon receptor
-
Payelle-Brogard B., Pellegrini S. Biochemical monitoring of the early endocytic traffic of the type I interferon receptor. J. Interferon Cytokine Res. 2010, 30:89-98.
-
(2010)
J. Interferon Cytokine Res.
, vol.30
, pp. 89-98
-
-
Payelle-Brogard, B.1
Pellegrini, S.2
-
50
-
-
33644522358
-
Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta
-
Jaitin D.A., et al. Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta. Mol. Cell. Biol. 2006, 26:1888-1897.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1888-1897
-
-
Jaitin, D.A.1
-
51
-
-
84883146392
-
Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1
-
de Weerd N.A., et al. Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1. Nat. Immunol. 2013, 14:901-907.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 901-907
-
-
de Weerd, N.A.1
-
52
-
-
33750037600
-
Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide
-
Thomas K.E., et al. Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide. J. Biol. Chem. 2006, 281:31119-31130.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 31119-31130
-
-
Thomas, K.E.1
-
53
-
-
0022619257
-
Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction
-
Larner A.C., et al. Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction. J. Biol. Chem. 1986, 261:453-459.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 453-459
-
-
Larner, A.C.1
-
54
-
-
33745761009
-
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
-
Malakhova O.A., et al. UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J. 2006, 25:2358-2367.
-
(2006)
EMBO J.
, vol.25
, pp. 2358-2367
-
-
Malakhova, O.A.1
-
55
-
-
79960313095
-
USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon alpha response
-
Francois-Newton V., et al. USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon alpha response. PLoS ONE 2011, 6:e22200.
-
(2011)
PLoS ONE
, vol.6
, pp. e22200
-
-
Francois-Newton, V.1
-
56
-
-
85044706808
-
Interferon-beta and interferon-lambda signaling is not affected by interferon-induced refractoriness to interferon-alpha in vivo
-
Makowska Z., et al. Interferon-beta and interferon-lambda signaling is not affected by interferon-induced refractoriness to interferon-alpha in vivo. Hepatology 2011, 53:1154-1163.
-
(2011)
Hepatology
, vol.53
, pp. 1154-1163
-
-
Makowska, Z.1
-
57
-
-
0036731485
-
Stats: transcriptional control and biological impact
-
Levy D.E., Darnell J.E. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 2002, 3:651-662.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell, J.E.2
-
58
-
-
79952237300
-
STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor
-
Perry S.T., et al. STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor. PLoS Pathog. 2011, 7:e1001297.
-
(2011)
PLoS Pathog.
, vol.7
, pp. e1001297
-
-
Perry, S.T.1
-
59
-
-
0033569905
-
P38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
-
Goh K.C., et al. p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. EMBO J. 1999, 18:5601-5608.
-
(1999)
EMBO J.
, vol.18
, pp. 5601-5608
-
-
Goh, K.C.1
-
60
-
-
42449150892
-
Role of the Akt pathway in mRNA translation of interferon-stimulated genes
-
Kaur S., et al. Role of the Akt pathway in mRNA translation of interferon-stimulated genes. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:4808-4813.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 4808-4813
-
-
Kaur, S.1
-
61
-
-
0028982917
-
Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase
-
Uddin S., et al. Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase. J. Biol. Chem. 1995, 270:15938-15941.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15938-15941
-
-
Uddin, S.1
-
62
-
-
34848817968
-
Acetylation-dependent signal transduction for type I interferon receptor
-
Tang X., et al. Acetylation-dependent signal transduction for type I interferon receptor. Cell 2007, 131:93-105.
-
(2007)
Cell
, vol.131
, pp. 93-105
-
-
Tang, X.1
-
63
-
-
33847687659
-
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity
-
Tenoever B.R., et al. Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science 2007, 315:1274-1278.
-
(2007)
Science
, vol.315
, pp. 1274-1278
-
-
Tenoever, B.R.1
-
64
-
-
0142152429
-
PIAS proteins promote SUMO-1 conjugation to STAT1
-
Ungureanu D., et al. PIAS proteins promote SUMO-1 conjugation to STAT1. Blood 2003, 102:3311-3313.
-
(2003)
Blood
, vol.102
, pp. 3311-3313
-
-
Ungureanu, D.1
-
65
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen Z., et al. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995, 82:241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
-
66
-
-
0034717054
-
Nipah virus: a recently emergent deadly paramyxovirus
-
Chua K.B., et al. Nipah virus: a recently emergent deadly paramyxovirus. Science 2000, 288:1432-1435.
-
(2000)
Science
, vol.288
, pp. 1432-1435
-
-
Chua, K.B.1
-
67
-
-
77955090647
-
Evolution of the mutation rate
-
Lynch M. Evolution of the mutation rate. Trends Genet. 2010, 26:345-352.
-
(2010)
Trends Genet.
, vol.26
, pp. 345-352
-
-
Lynch, M.1
-
68
-
-
0028852337
-
Translation initiation at alternate in-frame AUG codons in the rabies virus phosphoprotein mRNA is mediated by a ribosomal leaky scanning mechanism
-
Chenik M., et al. Translation initiation at alternate in-frame AUG codons in the rabies virus phosphoprotein mRNA is mediated by a ribosomal leaky scanning mechanism. J. Virol. 1995, 69:707-712.
-
(1995)
J. Virol.
, vol.69
, pp. 707-712
-
-
Chenik, M.1
-
69
-
-
0025145908
-
RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts
-
Paterson R.G., Lamb R.A. RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts. J. Virol. 1990, 64:4137-4145.
-
(1990)
J. Virol.
, vol.64
, pp. 4137-4145
-
-
Paterson, R.G.1
Lamb, R.A.2
-
70
-
-
0027938880
-
Paramyxovirus mRNA editing leads to G deletions as well as insertions
-
Jacques J.P., et al. Paramyxovirus mRNA editing leads to G deletions as well as insertions. EMBO J. 1994, 13:5496-5503.
-
(1994)
EMBO J.
, vol.13
, pp. 5496-5503
-
-
Jacques, J.P.1
-
71
-
-
64049083722
-
Nipah virus edits its P gene at high frequency to express the V and W proteins
-
Kulkarni S., et al. Nipah virus edits its P gene at high frequency to express the V and W proteins. J. Virol. 2009, 83:3982-3987.
-
(2009)
J. Virol.
, vol.83
, pp. 3982-3987
-
-
Kulkarni, S.1
-
72
-
-
0025141746
-
Editing of the Sendai virus P/C mRNA by G insertion occurs during mRNA synthesis via a virus-encoded activity
-
Vidal S., et al. Editing of the Sendai virus P/C mRNA by G insertion occurs during mRNA synthesis via a virus-encoded activity. J. Virol. 1990, 64:239-246.
-
(1990)
J. Virol.
, vol.64
, pp. 239-246
-
-
Vidal, S.1
-
73
-
-
0025359331
-
A stuttering model for paramyxovirus P mRNA editing
-
Vidal S., et al. A stuttering model for paramyxovirus P mRNA editing. EMBO J. 1990, 9:2017-2022.
-
(1990)
EMBO J.
, vol.9
, pp. 2017-2022
-
-
Vidal, S.1
-
74
-
-
59749095300
-
Mechanism of mda-5 inhibition by paramyxovirus V proteins
-
Childs K.S., et al. Mechanism of mda-5 inhibition by paramyxovirus V proteins. J. Virol. 2009, 83:1465-1473.
-
(2009)
J. Virol.
, vol.83
, pp. 1465-1473
-
-
Childs, K.S.1
-
75
-
-
46949097299
-
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
-
Kato H., et al. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 2008, 205:1601-1610.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1601-1610
-
-
Kato, H.1
-
76
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V., et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006, 314:994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
-
77
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
-
Pichlmair A., et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006, 314:997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
-
78
-
-
84908192059
-
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates
-
Goubau D., et al. Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates. Nature 2014, 514:372-375.
-
(2014)
Nature
, vol.514
, pp. 372-375
-
-
Goubau, D.1
-
79
-
-
33846863325
-
Mda-5, but not RIG-I, is a common target for paramyxovirus V proteins
-
Childs K., et al. Mda-5, but not RIG-I, is a common target for paramyxovirus V proteins. Virology 2007, 359:190-200.
-
(2007)
Virology
, vol.359
, pp. 190-200
-
-
Childs, K.1
-
80
-
-
84861304915
-
Paramyxovirus V proteins interact with the RNA helicase LGP2 to inhibit RIG-I-dependent interferon induction
-
Childs K., et al. Paramyxovirus V proteins interact with the RNA helicase LGP2 to inhibit RIG-I-dependent interferon induction. J. Virol. 2012, 86:3411-3421.
-
(2012)
J. Virol.
, vol.86
, pp. 3411-3421
-
-
Childs, K.1
-
81
-
-
67650439286
-
A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2
-
Parisien J.P., et al. A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2. J. Virol. 2009, 83:7252-7260.
-
(2009)
J. Virol.
, vol.83
, pp. 7252-7260
-
-
Parisien, J.P.1
-
82
-
-
76549109497
-
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
-
Satoh T., et al. LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:1512-1517.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 1512-1517
-
-
Satoh, T.1
-
83
-
-
54449099369
-
The multifunctional NS1 protein of influenza A viruses
-
Hale B.G., et al. The multifunctional NS1 protein of influenza A viruses. J. Gen. Virol. 2008, 89:2359-2376.
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 2359-2376
-
-
Hale, B.G.1
-
84
-
-
65549164536
-
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I
-
Gack M.U., et al. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe 2009, 5:439-449.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 439-449
-
-
Gack, M.U.1
-
85
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack M.U., et al. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 2007, 446:916-920.
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
-
86
-
-
84870820660
-
Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein
-
Rajsbaum R., et al. Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein. PLoS Pathog. 2012, 8:e1003059.
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1003059
-
-
Rajsbaum, R.1
-
87
-
-
59449091450
-
Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection
-
Oshiumi H., et al. Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection. J. Biol. Chem. 2009, 284:807-817.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 807-817
-
-
Oshiumi, H.1
-
88
-
-
78650189572
-
The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection
-
Oshiumi H., et al. The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection. Cell Host Microbe 2010, 8:496-509.
-
(2010)
Cell Host Microbe
, vol.8
, pp. 496-509
-
-
Oshiumi, H.1
-
89
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou F., et al. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 2011, 146:448-461.
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
-
90
-
-
34249855382
-
Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor
-
Yang Y., et al. Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:7253-7258.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 7253-7258
-
-
Yang, Y.1
-
91
-
-
29144462494
-
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
Li X.D., et al. Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:17717-17722.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 17717-17722
-
-
Li, X.D.1
-
92
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E., et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005, 437:1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
-
93
-
-
77955496554
-
The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein
-
Wei C., et al. The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J. Immunol. 2010, 185:1158-1168.
-
(2010)
J. Immunol.
, vol.185
, pp. 1158-1168
-
-
Wei, C.1
-
94
-
-
47249132062
-
Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1
-
Lu L.L., et al. Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1. J. Biol. Chem. 2008, 283:14269-14276.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14269-14276
-
-
Lu, L.L.1
-
95
-
-
84864118573
-
Inhibition of interferon regulatory factor 3 activation by paramyxovirus V protein
-
Irie T., et al. Inhibition of interferon regulatory factor 3 activation by paramyxovirus V protein. J. Virol. 2012, 86:7136-7145.
-
(2012)
J. Virol.
, vol.86
, pp. 7136-7145
-
-
Irie, T.1
-
96
-
-
18144378011
-
Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways
-
Shaw M.L., et al. Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways. J. Virol. 2005, 79:6078-6088.
-
(2005)
J. Virol.
, vol.79
, pp. 6078-6088
-
-
Shaw, M.L.1
-
97
-
-
84856918188
-
Measles virus C protein interferes with beta interferon transcription in the nucleus
-
Sparrer K.M., et al. Measles virus C protein interferes with beta interferon transcription in the nucleus. J. Virol. 2012, 86:796-805.
-
(2012)
J. Virol.
, vol.86
, pp. 796-805
-
-
Sparrer, K.M.1
-
98
-
-
0029972194
-
The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
-
Haspel R.L., et al. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J. 1996, 15:6262-6268.
-
(1996)
EMBO J.
, vol.15
, pp. 6262-6268
-
-
Haspel, R.L.1
-
99
-
-
0030851840
-
Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity
-
Lee C.K., et al. Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity. J. Biol. Chem. 1997, 272:21872-21877.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21872-21877
-
-
Lee, C.K.1
-
100
-
-
0035837045
-
The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2
-
Parisien J.P., et al. The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. Virology 2001, 283:230-239.
-
(2001)
Virology
, vol.283
, pp. 230-239
-
-
Parisien, J.P.1
-
101
-
-
0036827626
-
The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5
-
Andrejeva J., et al. The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5. J. Virol. 2002, 76:11379-11386.
-
(2002)
J. Virol.
, vol.76
, pp. 11379-11386
-
-
Andrejeva, J.1
-
102
-
-
65549090186
-
DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress
-
Leung-Pineda V., et al. DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress. Cancer Res. 2009, 69:2630-2637.
-
(2009)
Cancer Res.
, vol.69
, pp. 2630-2637
-
-
Leung-Pineda, V.1
-
103
-
-
0032530431
-
The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein
-
Lin G.Y., et al. The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein. Virology 1998, 249:189-200.
-
(1998)
Virology
, vol.249
, pp. 189-200
-
-
Lin, G.Y.1
-
104
-
-
79955416634
-
The cullin protein family
-
Sarikas A., et al. The cullin protein family. Genome Biol. 2011, 12:220.
-
(2011)
Genome Biol.
, vol.12
, pp. 220
-
-
Sarikas, A.1
-
105
-
-
0032731094
-
The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation
-
Didcock L., et al. The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation. J. Virol. 1999, 73:9928-9933.
-
(1999)
J. Virol.
, vol.73
, pp. 9928-9933
-
-
Didcock, L.1
-
106
-
-
0033520422
-
Stat protein transactivation domains recruit p300/CBP through widely divergent sequences
-
Paulson M., et al. Stat protein transactivation domains recruit p300/CBP through widely divergent sequences. J. Biol. Chem. 1999, 274:25343-25349.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25343-25349
-
-
Paulson, M.1
-
107
-
-
0036284219
-
STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication
-
Parisien J.P., et al. STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication. J. Virol. 2002, 76:6435-6441.
-
(2002)
J. Virol.
, vol.76
, pp. 6435-6441
-
-
Parisien, J.P.1
-
108
-
-
78349248232
-
Mouse STAT2 restricts early dengue virus replication
-
Ashour J., et al. Mouse STAT2 restricts early dengue virus replication. Cell Host Microbe 2010, 8:410-421.
-
(2010)
Cell Host Microbe
, vol.8
, pp. 410-421
-
-
Ashour, J.1
-
109
-
-
66149146738
-
NS5 of dengue virus mediates STAT2 binding and degradation
-
Ashour J., et al. NS5 of dengue virus mediates STAT2 binding and degradation. J. Virol. 2009, 83:5408-5418.
-
(2009)
J. Virol.
, vol.83
, pp. 5408-5418
-
-
Ashour, J.1
-
110
-
-
70349432365
-
Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation
-
Mazzon M., et al. Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation. J. Infect. Dis. 2009, 200:1261-1270.
-
(2009)
J. Infect. Dis.
, vol.200
, pp. 1261-1270
-
-
Mazzon, M.1
-
111
-
-
0038664389
-
STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling
-
Ulane C.M., et al. STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling. J. Virol. 2003, 77:6385-6393.
-
(2003)
J. Virol.
, vol.77
, pp. 6385-6393
-
-
Ulane, C.M.1
-
112
-
-
0036891861
-
C-terminal region of STAT-1alpha is not necessary for its ubiquitination and degradation caused by mumps virus V protein
-
Yokosawa N., et al. C-terminal region of STAT-1alpha is not necessary for its ubiquitination and degradation caused by mumps virus V protein. J. Virol. 2002, 76:12683-12690.
-
(2002)
J. Virol.
, vol.76
, pp. 12683-12690
-
-
Yokosawa, N.1
-
113
-
-
33744920357
-
Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation
-
Ho H.H., Ivashkiv L.B. Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation. J. Biol. Chem. 2006, 281:14111-14118.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14111-14118
-
-
Ho, H.H.1
Ivashkiv, L.B.2
-
114
-
-
0028349735
-
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong Z., et al. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994, 264:95-98.
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
-
115
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner R., et al. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin. Cancer Res. 2002, 8:945-954.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 945-954
-
-
Buettner, R.1
-
117
-
-
1042302005
-
The STATs of cancer - new molecular targets come of age
-
Yu H., Jove R. The STATs of cancer - new molecular targets come of age. Nat. Rev. Cancer 2004, 4:97-105.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
118
-
-
0036827851
-
Nipah virus V protein evades alpha and gamma interferons by preventing STAT1 and STAT2 activation and nuclear accumulation
-
Rodriguez J.J., et al. Nipah virus V protein evades alpha and gamma interferons by preventing STAT1 and STAT2 activation and nuclear accumulation. J. Virol. 2002, 76:11476-11483.
-
(2002)
J. Virol.
, vol.76
, pp. 11476-11483
-
-
Rodriguez, J.J.1
-
119
-
-
0142060816
-
Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulation
-
Rodriguez J.J., et al. Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulation. J. Virol. 2003, 77:11842-11845.
-
(2003)
J. Virol.
, vol.77
, pp. 11842-11845
-
-
Rodriguez, J.J.1
-
120
-
-
0036470732
-
Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways
-
Meyer T., et al. Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways. EMBO J. 2002, 21:344-354.
-
(2002)
EMBO J.
, vol.21
, pp. 344-354
-
-
Meyer, T.1
-
121
-
-
1942496600
-
Identification of the nuclear export signal and STAT-binding domains of the Nipah virus V protein reveals mechanisms underlying interferon evasion
-
Rodriguez J.J., et al. Identification of the nuclear export signal and STAT-binding domains of the Nipah virus V protein reveals mechanisms underlying interferon evasion. J. Virol. 2004, 78:5358-5367.
-
(2004)
J. Virol.
, vol.78
, pp. 5358-5367
-
-
Rodriguez, J.J.1
-
122
-
-
2442661542
-
Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively
-
Shaw M.L., et al. Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively. J. Virol. 2004, 78:5633-5641.
-
(2004)
J. Virol.
, vol.78
, pp. 5633-5641
-
-
Shaw, M.L.1
-
123
-
-
57149103678
-
Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2
-
Caignard G., et al. Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2. Virology 2009, 383:112-120.
-
(2009)
Virology
, vol.383
, pp. 112-120
-
-
Caignard, G.1
-
124
-
-
0037790930
-
STAT protein interference and suppression of cytokine signal transduction by measles virus V protein
-
Palosaari H., et al. STAT protein interference and suppression of cytokine signal transduction by measles virus V protein. J. Virol. 2003, 77:7635-7644.
-
(2003)
J. Virol.
, vol.77
, pp. 7635-7644
-
-
Palosaari, H.1
-
125
-
-
35648940788
-
Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling
-
Caignard G., et al. Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling. Virology 2007, 368:351-362.
-
(2007)
Virology
, vol.368
, pp. 351-362
-
-
Caignard, G.1
-
126
-
-
0037864215
-
Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation
-
Takeuchi K., et al. Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation. FEBS Lett. 2003, 545:177-182.
-
(2003)
FEBS Lett.
, vol.545
, pp. 177-182
-
-
Takeuchi, K.1
-
127
-
-
0029069540
-
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
-
Yu C.L., et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 1995, 269:81-83.
-
(1995)
Science
, vol.269
, pp. 81-83
-
-
Yu, C.L.1
-
128
-
-
0037320240
-
The amino-terminal extensions of the longer Sendai virus C proteins modulate pY701-Stat1 and bulk Stat1 levels independently of interferon signaling
-
Garcin D., et al. The amino-terminal extensions of the longer Sendai virus C proteins modulate pY701-Stat1 and bulk Stat1 levels independently of interferon signaling. J. Virol. 2003, 77:2321-2329.
-
(2003)
J. Virol.
, vol.77
, pp. 2321-2329
-
-
Garcin, D.1
-
129
-
-
0037334497
-
The STAT2 activation process is a crucial target of Sendai virus C protein for the blockade of alpha interferon signaling
-
Gotoh B., et al. The STAT2 activation process is a crucial target of Sendai virus C protein for the blockade of alpha interferon signaling. J. Virol. 2003, 77:3360-3370.
-
(2003)
J. Virol.
, vol.77
, pp. 3360-3370
-
-
Gotoh, B.1
-
130
-
-
0036058864
-
Dephosphorylation failure of tyrosine-phosphorylated STAT1 in IFN-stimulated Sendai virus C protein-expressing cells
-
Saito S., et al. Dephosphorylation failure of tyrosine-phosphorylated STAT1 in IFN-stimulated Sendai virus C protein-expressing cells. Virology 2002, 293:205-209.
-
(2002)
Virology
, vol.293
, pp. 205-209
-
-
Saito, S.1
-
131
-
-
0037196382
-
Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1
-
Komatsu T., et al. Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1. FEBS Lett. 2002, 511:139-144.
-
(2002)
FEBS Lett.
, vol.511
, pp. 139-144
-
-
Komatsu, T.1
-
132
-
-
84857088880
-
The C proteins of human parainfluenza virus type 1 block IFN signaling by binding and retaining Stat1 in perinuclear aggregates at the late endosome
-
Schomacker H., et al. The C proteins of human parainfluenza virus type 1 block IFN signaling by binding and retaining Stat1 in perinuclear aggregates at the late endosome. PLoS ONE 2012, 7:e28382.
-
(2012)
PLoS ONE
, vol.7
, pp. e28382
-
-
Schomacker, H.1
-
133
-
-
33646754920
-
Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation
-
Reid S.P., et al. Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation. J. Virol. 2006, 80:5156-5167.
-
(2006)
J. Virol.
, vol.80
, pp. 5156-5167
-
-
Reid, S.P.1
-
134
-
-
37149040796
-
Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1
-
Reid S.P., et al. Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. J. Virol. 2007, 81:13469-13477.
-
(2007)
J. Virol.
, vol.81
, pp. 13469-13477
-
-
Reid, S.P.1
-
135
-
-
79955407974
-
Marburg virus VP40 antagonizes interferon signaling in a species-specific manner
-
Valmas C., Basler C.F. Marburg virus VP40 antagonizes interferon signaling in a species-specific manner. J. Virol. 2011, 85:4309-4317.
-
(2011)
J. Virol.
, vol.85
, pp. 4309-4317
-
-
Valmas, C.1
Basler, C.F.2
-
136
-
-
77649195743
-
Marburg virus evades interferon responses by a mechanism distinct from ebola virus
-
Valmas C., et al. Marburg virus evades interferon responses by a mechanism distinct from ebola virus. PLoS Pathog. 2010, 6:e1000721.
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000721
-
-
Valmas, C.1
-
137
-
-
84885869823
-
IFNbeta-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
-
Cheon H., et al. IFNbeta-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage. EMBO J. 2013, 32:2751-2763.
-
(2013)
EMBO J.
, vol.32
, pp. 2751-2763
-
-
Cheon, H.1
-
138
-
-
4644316070
-
Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response
-
Abate D.A., et al. Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response. J. Virol. 2004, 78:10995-11006.
-
(2004)
J. Virol.
, vol.78
, pp. 10995-11006
-
-
Abate, D.A.1
-
139
-
-
3543054546
-
Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production
-
Melroe G.T., et al. Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J. Virol. 2004, 78:8411-8420.
-
(2004)
J. Virol.
, vol.78
, pp. 8411-8420
-
-
Melroe, G.T.1
-
140
-
-
77951227282
-
Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen inhibits interferon (IFN) beta expression by competing with IFN regulatory factor-3 for binding to IFNB promoter
-
Cloutier N., Flamand L. Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen inhibits interferon (IFN) beta expression by competing with IFN regulatory factor-3 for binding to IFNB promoter. J. Biol. Chem. 2010, 285:7208-7221.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7208-7221
-
-
Cloutier, N.1
Flamand, L.2
-
141
-
-
0038315187
-
Transcription mapping of human herpesvirus 8 genes encoding viral interferon regulatory factors
-
Cunningham C., et al. Transcription mapping of human herpesvirus 8 genes encoding viral interferon regulatory factors. J. Gen. Virol. 2003, 84:1471-1483.
-
(2003)
J. Gen. Virol.
, vol.84
, pp. 1471-1483
-
-
Cunningham, C.1
-
142
-
-
0030925274
-
Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity?
-
Neipel F., et al. Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity?. J. Virol. 1997, 71:4187-4192.
-
(1997)
J. Virol.
, vol.71
, pp. 4187-4192
-
-
Neipel, F.1
-
143
-
-
0000842916
-
Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)
-
Russo J.J., et al. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc. Natl. Acad. Sci. U.S.A. 1996, 93:14862-14867.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 14862-14867
-
-
Russo, J.J.1
-
144
-
-
0344564198
-
Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300
-
Burysek L., et al. Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300. J. Virol. 1999, 73:7334-7342.
-
(1999)
J. Virol.
, vol.73
, pp. 7334-7342
-
-
Burysek, L.1
-
145
-
-
0035864786
-
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators
-
Lin R., et al. HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators. Oncogene 2001, 20:800-811.
-
(2001)
Oncogene
, vol.20
, pp. 800-811
-
-
Lin, R.1
-
146
-
-
59649113242
-
Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway
-
Wang J.T., et al. Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway. J. Virol. 2009, 83:1856-1869.
-
(2009)
J. Virol.
, vol.83
, pp. 1856-1869
-
-
Wang, J.T.1
-
147
-
-
33751203273
-
The Epstein-Barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells
-
Geiger T.R., Martin J.M. The Epstein-Barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells. J. Virol. 2006, 80:11638-11650.
-
(2006)
J. Virol.
, vol.80
, pp. 11638-11650
-
-
Geiger, T.R.1
Martin, J.M.2
-
148
-
-
0032128003
-
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity
-
Ronco L.V., et al. Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev. 1998, 12:2061-2072.
-
(1998)
Genes Dev.
, vol.12
, pp. 2061-2072
-
-
Ronco, L.V.1
-
149
-
-
80052474239
-
Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance
-
Hong S., et al. Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance. J. Virol. 2011, 85:9486-9494.
-
(2011)
J. Virol.
, vol.85
, pp. 9486-9494
-
-
Hong, S.1
-
150
-
-
0033554631
-
The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha
-
Li S., et al. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha. Oncogene 1999, 18:5727-5737.
-
(1999)
Oncogene
, vol.18
, pp. 5727-5737
-
-
Li, S.1
-
151
-
-
0033526860
-
The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha
-
Barnard P., McMillan N.A. The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha. Virology 1999, 259:305-313.
-
(1999)
Virology
, vol.259
, pp. 305-313
-
-
Barnard, P.1
McMillan, N.A.2
-
152
-
-
0032544059
-
Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3
-
Juang Y.T., et al. Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:9837-9842.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 9837-9842
-
-
Juang, Y.T.1
-
153
-
-
0029665857
-
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
-
Yang X.J., et al. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 1996, 382:319-324.
-
(1996)
Nature
, vol.382
, pp. 319-324
-
-
Yang, X.J.1
-
154
-
-
0032432076
-
Direct suppression of Stat1 function during adenoviral infection
-
Look D.C., et al. Direct suppression of Stat1 function during adenoviral infection. Immunity 1998, 9:871-880.
-
(1998)
Immunity
, vol.9
, pp. 871-880
-
-
Look, D.C.1
-
155
-
-
0035051928
-
West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays
-
Davis B.S., et al. West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays. J. Virol. 2001, 75:4040-4047.
-
(2001)
J. Virol.
, vol.75
, pp. 4040-4047
-
-
Davis, B.S.1
-
156
-
-
84878173821
-
Cytosolic sensing of viruses
-
Goubau D., et al. Cytosolic sensing of viruses. Immunity 2013, 38:855-869.
-
(2013)
Immunity
, vol.38
, pp. 855-869
-
-
Goubau, D.1
-
157
-
-
27144508442
-
Innate immune recognition of nucleic acids: beyond toll-like receptors
-
Ishii K.J., Akira S. Innate immune recognition of nucleic acids: beyond toll-like receptors. Int. J. Cancer 2005, 117:517-523.
-
(2005)
Int. J. Cancer
, vol.117
, pp. 517-523
-
-
Ishii, K.J.1
Akira, S.2
-
158
-
-
80052184362
-
Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity
-
Kawasaki T., et al. Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity. Immunol. Rev. 2011, 243:61-73.
-
(2011)
Immunol. Rev.
, vol.243
, pp. 61-73
-
-
Kawasaki, T.1
-
159
-
-
84855486511
-
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
-
Caskey M., et al. Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans. J. Exp. Med. 2011, 208:2357-2366.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2357-2366
-
-
Caskey, M.1
-
160
-
-
84868547474
-
Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques
-
Stahl-Hennig C., et al. Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques. PLoS Pathog. 2009, 5:e1000373.
-
(2009)
PLoS Pathog.
, vol.5
, pp. e1000373
-
-
Stahl-Hennig, C.1
-
161
-
-
23944497673
-
Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells
-
Patole P.S., et al. Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells. J. Am. Soc. Nephrol. 2005, 16:1326-1338.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 1326-1338
-
-
Patole, P.S.1
-
162
-
-
77953212611
-
Structure-activity relationships in human toll-like receptor 7-active imidazoquinoline analogues
-
Shukla N.M., et al. Structure-activity relationships in human toll-like receptor 7-active imidazoquinoline analogues. J. Med. Chem. 2010, 53:4450-4465.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 4450-4465
-
-
Shukla, N.M.1
-
163
-
-
79956306542
-
The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691)
-
Fidock M.D., et al. The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691). Clin. Pharmacol. Ther. 2011, 89:821-829.
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 821-829
-
-
Fidock, M.D.1
-
164
-
-
36949030224
-
Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine
-
Xiang A.X., et al. Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine. Nucleosides Nucleotides Nucleic Acids 2007, 26:635-640.
-
(2007)
Nucleosides Nucleotides Nucleic Acids
, vol.26
, pp. 635-640
-
-
Xiang, A.X.1
-
165
-
-
70450200218
-
Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists
-
Hamm S., et al. Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists. J. Immunotoxicol. 2009, 6:257-265.
-
(2009)
J. Immunotoxicol.
, vol.6
, pp. 257-265
-
-
Hamm, S.1
-
166
-
-
0036242206
-
Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo
-
Dalpke A.H., et al. Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo. Immunology 2002, 106:102-112.
-
(2002)
Immunology
, vol.106
, pp. 102-112
-
-
Dalpke, A.H.1
-
167
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
-
Krug A., et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur. J. Immunol. 2001, 31:2154-2163.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2154-2163
-
-
Krug, A.1
-
168
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg A.M., et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995, 374:546-549.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
-
169
-
-
79955088827
-
Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV safety and efficacy
-
Cooper C., Mackie D. Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV safety and efficacy. Expert Rev. Vaccines 2011, 10:417-427.
-
(2011)
Expert Rev. Vaccines
, vol.10
, pp. 417-427
-
-
Cooper, C.1
Mackie, D.2
-
170
-
-
3042548183
-
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
-
Boule M.W., et al. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J. Exp. Med. 2004, 199:1631-1640.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1631-1640
-
-
Boule, M.W.1
-
171
-
-
22944490869
-
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
-
Christensen S.R., et al. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J. Exp. Med. 2005, 202:321-331.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 321-331
-
-
Christensen, S.R.1
-
172
-
-
0033038486
-
Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis
-
Deng G.M., et al. Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis. Nat. Med. 1999, 5:702-705.
-
(1999)
Nat. Med.
, vol.5
, pp. 702-705
-
-
Deng, G.M.1
-
173
-
-
33846190681
-
TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat
-
Zipris D., et al. TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat. J. Immunol. 2007, 178:693-701.
-
(2007)
J. Immunol.
, vol.178
, pp. 693-701
-
-
Zipris, D.1
-
174
-
-
84879385334
-
CGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING
-
Ablasser A., et al. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature 2013, 498:380-384.
-
(2013)
Nature
, vol.498
, pp. 380-384
-
-
Ablasser, A.1
-
175
-
-
67651125824
-
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
-
McWhirter S.M., et al. A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. J. Exp. Med. 2009, 206:1899-1911.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1899-1911
-
-
McWhirter, S.M.1
-
176
-
-
84869208004
-
5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential
-
Prantner D., et al. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential. J. Biol. Chem. 2012, 287:39776-39788.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 39776-39788
-
-
Prantner, D.1
-
177
-
-
34447330454
-
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis
-
Roberts Z.J., et al. The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. J. Exp. Med. 2007, 204:1559-1569.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1559-1569
-
-
Roberts, Z.J.1
-
178
-
-
84877795529
-
Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid
-
Conlon J., et al. Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid. J. Immunol. 2013, 190:5216-5225.
-
(2013)
J. Immunol.
, vol.190
, pp. 5216-5225
-
-
Conlon, J.1
-
179
-
-
68249131533
-
3',5'-Cyclic diguanylic acid elicits mucosal immunity against bacterial infection
-
Yan H., et al. 3',5'-Cyclic diguanylic acid elicits mucosal immunity against bacterial infection. Biochem. Biophys. Res. Commun. 2009, 387:581-584.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.387
, pp. 581-584
-
-
Yan, H.1
-
180
-
-
79960291542
-
Bis-(3',5')-cyclic dimeric adenosine monophosphate: strong Th1/Th2/Th17 promoting mucosal adjuvant
-
Ebensen T., et al. Bis-(3',5')-cyclic dimeric adenosine monophosphate: strong Th1/Th2/Th17 promoting mucosal adjuvant. Vaccine 2011, 29:5210-5220.
-
(2011)
Vaccine
, vol.29
, pp. 5210-5220
-
-
Ebensen, T.1
-
181
-
-
84874244715
-
IFN-alpha subtypes: distinct biological activities in anti-viral therapy
-
Gibbert K., et al. IFN-alpha subtypes: distinct biological activities in anti-viral therapy. Br. J. Pharmacol. 2013, 168:1048-1058.
-
(2013)
Br. J. Pharmacol.
, vol.168
, pp. 1048-1058
-
-
Gibbert, K.1
-
182
-
-
9644262469
-
Interferons, interferon-like cytokines, and their receptors
-
Pestka S., et al. Interferons, interferon-like cytokines, and their receptors. Immunol. Rev. 2004, 202:8-32.
-
(2004)
Immunol. Rev.
, vol.202
, pp. 8-32
-
-
Pestka, S.1
-
183
-
-
0842266786
-
Interferon-gamma: an overview of signals, mechanisms and functions
-
Schroder K., et al. Interferon-gamma: an overview of signals, mechanisms and functions. J. Leukoc. Biol. 2004, 75:163-189.
-
(2004)
J. Leukoc. Biol.
, vol.75
, pp. 163-189
-
-
Schroder, K.1
-
184
-
-
0037243222
-
IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
-
Kotenko S.V., et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat. Immunol. 2003, 4:69-77.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 69-77
-
-
Kotenko, S.V.1
-
185
-
-
84873083416
-
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
-
Prokunina-Olsson L., et al. A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat. Genet. 2013, 45:164-171.
-
(2013)
Nat. Genet.
, vol.45
, pp. 164-171
-
-
Prokunina-Olsson, L.1
-
186
-
-
0037236826
-
IL-28, IL-29 and their class II cytokine receptor IL-28R
-
Sheppard P., et al. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat. Immunol. 2003, 4:63-68.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 63-68
-
-
Sheppard, P.1
-
187
-
-
42949160129
-
IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo
-
Sommereyns C., et al. IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo. PLoS Pathog. 2008, 4:e1000017.
-
(2008)
PLoS Pathog.
, vol.4
, pp. e1000017
-
-
Sommereyns, C.1
-
188
-
-
84896987305
-
Interferon-stimulated genes: a complex web of host defenses
-
Schneider W.M., et al. Interferon-stimulated genes: a complex web of host defenses. Annu. Rev. Immunol. 2014, 32:513-545.
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 513-545
-
-
Schneider, W.M.1
-
189
-
-
84924265294
-
Dynamic control of type I IFN signalling by an integrated network of negative regulators
-
Poritt R.A., Hertzog P.J. Dynamic control of type I IFN signalling by an integrated network of negative regulators. Trends Immunol. 2015, 10.1016/j.it.2015.02.002.
-
(2015)
Trends Immunol.
-
-
Poritt, R.A.1
Hertzog, P.J.2
-
190
-
-
84924240604
-
The molecular basis for functional plasticity in type I interferon signaling
-
Schreiber G., Piehler J. The molecular basis for functional plasticity in type I interferon signaling. Trends Immunol. 2015, 10.1016/j.it.2015.01.002.
-
(2015)
Trends Immunol.
-
-
Schreiber, G.1
Piehler, J.2
|