Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of κB kinase ε (IKKe)/TBK1

Journal of Biological Chemistry

Volumn 283, Issue 21, 2008, Pages 14269-14276

  Lu, Lenette L ^a,b   Puri, Mamta ^c   Horvath, Curt M ^c   Sen, Ganes C ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; IMMUNOLOGY; NUCLEIC ACIDS; ORGANIC ACIDS; PHOSPHORYLATION; RNA; VIRUSES;

ACCESSORY PROTEINS; ALTERNATIVE SUBSTRATES; ANTIVIRAL EFFECTS; BINDING KINASES; CELL SURVIVAL ASSAYS; CELLULAR LEVELS; FAMILY MEMBERS; GENE INDUCTIONS; INNATE IMMUNE RESPONSES; INTERFERON REGULATORY FACTOR 3; SIGNALING PATHWAYS; TERMINAL KINASES;

PROTEINS;

CYTOKINE; DOUBLE STRANDED RNA; I KAPPA B KINASE EPSILON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; VIRUS PROTEIN V; I KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; VIRUS PROTEIN;

ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME SUBSTRATE; GENE INDUCTION; MUMPS VIRUS; NONHUMAN; PARAINFLUENZA VIRUS; PARAINFLUENZA VIRUS 2; PARAINFLUENZA VIRUS 5; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VIRUS REPLICATION; ANIMAL; CELL LINE; CERCOPITHECUS; DRUG ANTAGONISM; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PARAMYXOVIRUS; PHOSPHORYLATION; PROTEIN BINDING;

HUMAN PARAINFLUENZA VIRUS 2; MUMPS VIRUS; PARAINFLUENZA VIRUS; RUBULAVIRUS;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; INTERFERON REGULATORY FACTOR-3; PARAMYXOVIRIDAE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TOLL-LIKE RECEPTOR 3; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 47249132062     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710089200     Document Type: Article

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