LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 4, 2010, Pages 1512-1517

  Satoh, Takashi ^a   Kato, Hiroki ^a,e   Kumagai, Yutaro ^a   Yoneyama, Mitsutoshi ^b,c   Sato, Shintaro ^a,f   Matsushita, Kazufumi ^a   Tsujimura, Tohru ^d   Fujita, Takashi ^b   Akira, Shizuo ^a   Takeuchi, Osamu ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Innate immunity; Type I interferon; Virus infection

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BETA INTERFERON; PROTEIN; PROTEIN LGP2; PROTEIN MDA5; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; ENZYME ACTIVITY; FEMALE; INTERFERON PRODUCTION; MOUSE; NONHUMAN; PICORNAVIRUS INFECTION; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; VIRUS INHIBITION;

ANIMALS; CARDIOVIRUS INFECTIONS; CELL LINE; DEAD-BOX RNA HELICASES; ENCEPHALOMYOCARDITIS VIRUS; FEMALE; INTERFERON-BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RNA HELICASES; RNA, VIRAL; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ENCEPHALOMYOCARDITIS VIRUS; MUS; PICORNAVIRIDAE; RNA VIRUSES;

EID: 76549109497     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912986107     Document Type: Article

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