메뉴 건너뛰기




Volumn 8, Issue 4, 2002, Pages 945-954

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BCR ABL PROTEIN; CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN D2; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR; INHIBITOR OF APOPTOSIS PROTEIN; JANUS KINASE; MYC PROTEIN; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STAT PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN;

EID: 0036554816     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (997)

References (113)
  • 1
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J. E., Jr., Kerr, I. M., and Stark, G. R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science (Wash. DC), 264: 1415-1421, 1994.
    • (1994) Science (Wash. DC) , vol.264 , pp. 1415-1421
    • Darnell J.E., Jr.1    Kerr, I.M.2    Stark, G.R.3
  • 2
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg, J., and Darnell, J. E., Jr. The role of STATs in transcriptional control and their impact on cellular function. Oncogene, 19: 2468-2473, 2000.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell J.E., Jr.2
  • 3
    • 0031821617 scopus 로고    scopus 로고
    • Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway
    • Darnell, J. E., Jr. Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway. J. Interferon Cytokine Res., 18: 549-554, 1998.
    • (1998) J. Interferon Cytokine Res. , vol.18 , pp. 549-554
    • Darnell J.E., Jr.1
  • 4
    • 0032869581 scopus 로고    scopus 로고
    • Transcription factor activity of STAT proteins: Structural requirements and regulation by phosphorylation and interacting proteins
    • Decker, T., and Kovarik, P. Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins. Cell. Mol. Life Sci, 55: 1535-1546, 1999.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1535-1546
    • Decker, T.1    Kovarik, P.2
  • 5
    • 0032832056 scopus 로고    scopus 로고
    • Interferons as a paradigm for cytokine signal transduction
    • Schindler, C., and Brutsaert, S. Interferons as a paradigm for cytokine signal transduction. Cell. Mol. Life Sci., 55: 1509-1522, 1999.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1509-1522
    • Schindler, C.1    Brutsaert, S.2
  • 6
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell, J. E., Jr. STATs and gene regulation. Science (Wash. DC), 277: 1630-1635, 1997.
    • (1997) Science (Wash. DC) , vol.277 , pp. 1630-1635
    • Darnell J.E., Jr.1
  • 7
    • 0034658501 scopus 로고    scopus 로고
    • The biology of Stat4 and Stat6
    • Wurster, A. L., Tanaka, T., and Grusby, M. J. The biology of Stat4 and Stat6. Oncogene, 19: 2577-2584, 2000.
    • (2000) Oncogene , vol.19 , pp. 2577-2584
    • Wurster, A.L.1    Tanaka, T.2    Grusby, M.J.3
  • 8
    • 0034657958 scopus 로고    scopus 로고
    • Roles of STAT3 defined by tissue-specific gene targeting
    • Akira, S. Roles of STAT3 defined by tissue-specific gene targeting. Oncogene, 19: 2607-2611, 2000.
    • (2000) Oncogene , vol.19 , pp. 2607-2611
    • Akira, S.1
  • 9
    • 0032855770 scopus 로고    scopus 로고
    • Physiological significance of STAT proteins: Investigations through gene disruption in vivo
    • Levy, D. E. Physiological significance of STAT proteins: investigations through gene disruption in vivo. Cell. Mol. Life Sci., 55: 1559-1567, 1999.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1559-1567
    • Levy, D.E.1
  • 10
    • 0028845212 scopus 로고
    • Cytokine receptor signaling
    • Ihle, J. N. Cytokine receptor signaling. Nature (Lond.), 377: 591-594, 1995.
    • (1995) Nature (Lond.) , vol.377 , pp. 591-594
    • Ihle, J.N.1
  • 11
  • 12
    • 0034658583 scopus 로고    scopus 로고
    • Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
    • Kotenko, S. V., and Pestka, S. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene, 19: 2557-2565, 2000.
    • (2000) Oncogene , vol.19 , pp. 2557-2565
    • Kotenko, S.V.1    Pestka, S.2
  • 13
    • 0032827836 scopus 로고    scopus 로고
    • JAKs and STATs in invertebrate model systems
    • Dearolf, C. R. JAKs and STATs in invertebrate model systems. Cell. Mol. Life Sci., 55: 1578-1584, 1999.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1578-1584
    • Dearolf, C.R.1
  • 14
    • 0034657396 scopus 로고    scopus 로고
    • The role of Stat5a and Stat5b in signaling by IL-2 family cytokines
    • Lin, J. X., and Leonard, W. J. The role of Stat5a and Stat5b in signaling by IL-2 family cytokines. Oncogene, 19: 2566-2576, 2000.
    • (2000) Oncogene , vol.19 , pp. 2566-2576
    • Lin, J.X.1    Leonard, W.J.2
  • 15
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C., and Darnell, J. E. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem., 64: 621-651, 1995.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell, J.E.2
  • 16
    • 0034657415 scopus 로고    scopus 로고
    • The roles of the Drosophila Jak/Stat pathway
    • Zeidler, M. P., Bach, E. A., and Perrimon, N. The roles of the Drosophila Jak/Stat pathway. Oncogene, 19: 2598-2606, 2000.
    • (2000) Oncogene , vol.19 , pp. 2598-2606
    • Zeidler, M.P.1    Bach, E.A.2    Perrimon, N.3
  • 17
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation, and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano, T., Ishihara, K., and Hibi, M. Roles of STAT3 in mediating the cell growth, differentiation, and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene, 19: 2548-2556, 2000.
    • (2000) Oncogene , vol.19 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 19
    • 0032877019 scopus 로고    scopus 로고
    • The role of STATs in proliferation, differentiation, and apoptosis
    • Mui, A. L. The role of STATs in proliferation, differentiation, and apoptosis. Cell. Mol. Life Sci., 55: 1547-1558, 1999.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1547-1558
    • Mui, A.L.1
  • 20
    • 0035313701 scopus 로고    scopus 로고
    • The Stat family in cytokine signaling
    • Ihle, J. N. The Stat family in cytokine signaling. Curr. Opin. Cell Biol., 13: 211-217, 2001.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 211-217
    • Ihle, J.N.1
  • 21
    • 0034657348 scopus 로고    scopus 로고
    • The role of STAT proteins in growth hormone signaling
    • Herrington, J., Smit, L. S., Schwartz, J., and Carter-Su, C. The role of STAT proteins in growth hormone signaling. Oncogene, 19: 2585-2597, 2000.
    • (2000) Oncogene , vol.19 , pp. 2585-2597
    • Herrington, J.1    Smit, L.S.2    Schwartz, J.3    Carter-Su, C.4
  • 22
    • 0034657447 scopus 로고    scopus 로고
    • IL-3 signaling and the role of Src kinases. JAKs and STATs: A covert liaison unveiled
    • Reddy, E. P., Korapati, A., Chaturvedi, P., and Rane, S. IL-3 signaling and the role of Src kinases. JAKs and STATs: a covert liaison unveiled. Oncogene, 19: 2532-2547, 2000.
    • (2000) Oncogene , vol.19 , pp. 2532-2547
    • Reddy, E.P.1    Korapati, A.2    Chaturvedi, P.3    Rane, S.4
  • 23
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • Turkson, J., and Jove, R. STAT proteins: novel molecular targets for cancer drug discovery. Oncogene, 19: 6613-6626, 2000.
    • (2000) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 24
    • 0031800697 scopus 로고    scopus 로고
    • Activation of STAT transcription factors in oncogenic tyrosine kinase signaling
    • Garcia, R., and Jove, R. Activation of STAT transcription factors in oncogenic tyrosine kinase signaling. J. Biomed. Sci., 5: 79-85, 1998.
    • (1998) J. Biomed. Sci. , vol.5 , pp. 79-85
    • Garcia, R.1    Jove, R.2
  • 25
    • 0032726122 scopus 로고    scopus 로고
    • STAT proteins as novel targets for cancer therapy. Signal transducer and activator of transcription
    • Catlett-Falcone, R., Dalton, W. S., and Jove, R. STAT proteins as novel targets for cancer therapy. Signal transducer and activator of transcription. Curr. Opin. Oncol., 11: 490-496, 1999.
    • (1999) Curr. Opin. Oncol. , vol.11 , pp. 490-496
    • Catlett-Falcone, R.1    Dalton, W.S.2    Jove, R.3
  • 27
    • 0034658499 scopus 로고    scopus 로고
    • STAT signaling in head and neck cancer
    • Song, J. I., and Grandis, J. R. STAT signaling in head and neck cancer. Oncogene, 19: 2489-2495, 2000.
    • (2000) Oncogene , vol.19 , pp. 2489-2495
    • Song, J.I.1    Grandis, J.R.2
  • 28
    • 0034658551 scopus 로고    scopus 로고
    • The role of STATs in myeloid differentiation and leukemia
    • Coffer, P. J., Koenderman, L., and de Groot, R. P. The role of STATs in myeloid differentiation and leukemia. Oncogene, 19: 2511-2522, 2000.
    • (2000) Oncogene , vol.19 , pp. 2511-2522
    • Coffer, P.J.1    Koenderman, L.2    De Groot, R.P.3
  • 29
    • 0034658153 scopus 로고    scopus 로고
    • STAT signaling in the pathogenesis and treatment of leukemias
    • Lin, T. S., Mahajan, S., and Frank, D. A. STAT signaling in the pathogenesis and treatment of leukemias. Oncogene, 19: 2496-2504, 2000.
    • (2000) Oncogene , vol.19 , pp. 2496-2504
    • Lin, T.S.1    Mahajan, S.2    Frank, D.A.3
  • 32
    • 0029799912 scopus 로고    scopus 로고
    • Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon α and interferon γ
    • Bromberg, J. F., Horvath, C. M., Wen, Z., Schreiber, R. D., and Darnell, J. E., Jr. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon α and interferon γ. Proc. Natl. Acad. Sci. USA, 93: 7673-7678, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7673-7678
    • Bromberg, J.F.1    Horvath, C.M.2    Wen, Z.3    Schreiber, R.D.4    Darnell J.E., Jr.5
  • 34
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Durbin, J. E., Hackenmiller, R., Simon, M. C., and Levy, D. E. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell, 84: 443-450, 1996.
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 36
    • 0034658690 scopus 로고    scopus 로고
    • Divergent roles of Stat1 and Stat5 in malignancy as revealed by gene disruptions in mice
    • Levy, D. E., and Gilliland, D. G. Divergent roles of Stat1 and Stat5 in malignancy as revealed by gene disruptions in mice. Oncogene, 19: 2505-2510, 2000.
    • (2000) Oncogene , vol.19 , pp. 2505-2510
    • Levy, D.E.1    Gilliland, D.G.2
  • 37
    • 0033151612 scopus 로고    scopus 로고
    • FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
    • Sahni, M., Ambrosetti, D. C., Mansukhani, A., Gertner, R., Levy, D., and Basilico, C. FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev., 13: 1361-1366, 1999.
    • (1999) Genes Dev. , vol.13 , pp. 1361-1366
    • Sahni, M.1    Ambrosetti, D.C.2    Mansukhani, A.3    Gertner, R.4    Levy, D.5    Basilico, C.6
  • 38
    • 0013689209 scopus 로고    scopus 로고
    • Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro
    • Grandis, J. R., Drenning, S. D., Chakraborty, A., Zhou, M. Y., Zeng, Q., Pitt, A. S., and Tweardy, D. J. Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro. J. Clin. Investig., 102: 1385-1392, 1998.
    • (1998) J. Clin. Investig. , vol.102 , pp. 1385-1392
    • Grandis, J.R.1    Drenning, S.D.2    Chakraborty, A.3    Zhou, M.Y.4    Zeng, Q.5    Pitt, A.S.6    Tweardy, D.J.7
  • 39
    • 0034677195 scopus 로고    scopus 로고
    • Regulation of c-myc expression by IFN-γ through Stat1-dependent and -independent pathways
    • Ramana, C. V., Grammatikakis, N., Chernov, M., Nguyen, H., Goh, K. C., Williams, B. R., and Stark, G. R. Regulation of c-myc expression by IFN-γ through Stat1-dependent and -independent pathways. EMBO J., 19: 263-272, 2000.
    • (2000) EMBO J. , vol.19 , pp. 263-272
    • Ramana, C.V.1    Grammatikakis, N.2    Chernov, M.3    Nguyen, H.4    Goh, K.C.5    Williams, B.R.6    Stark, G.R.7
  • 40
    • 0035353191 scopus 로고    scopus 로고
    • Down-regulation of interleukin-3/granulocyte-macrophage colony-stimulating factor receptor β-chain in BCR-ABL(+) human leukemic cells: Association with loss of cytokine-mediated Stat-5 activation and protection from apoptosis after BCR-ABL inhibition
    • Donato, N. J., Wu, J. Y., Zhang, L., Kantarjian, H., and Talpaz, M. Down-regulation of interleukin-3/granulocyte-macrophage colony-stimulating factor receptor β-chain in BCR-ABL(+) human leukemic cells: association with loss of cytokine-mediated Stat-5 activation and protection from apoptosis after BCR-ABL inhibition. Blood, 97: 2846-2853, 2001.
    • (2001) Blood , vol.97 , pp. 2846-2853
    • Donato, N.J.1    Wu, J.Y.2    Zhang, L.3    Kantarjian, H.4    Talpaz, M.5
  • 42
    • 0028946158 scopus 로고
    • Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway
    • Heim, M. H., Kerr, I. M., Stark, G. R., and Darnell, J. E., Jr. Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway. Science (Wash. DC), 267: 1347-1349, 1995.
    • (1995) Science (Wash. DC) , vol.267 , pp. 1347-1349
    • Heim, M.H.1    Kerr, I.M.2    Stark, G.R.3    Darnell J.E., Jr.4
  • 43
    • 0034657999 scopus 로고    scopus 로고
    • Jak-Stat signaling activated by Abl oncogenes
    • Danial, N. N., and Rothman, P., Jak-Stat signaling activated by Abl oncogenes. Oncogene, 19: 2523-2531, 2000.
    • (2000) Oncogene , vol.19 , pp. 2523-2531
    • Danial, N.N.1    Rothman, P.2
  • 44
    • 0032577678 scopus 로고    scopus 로고
    • Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
    • Chen, X., Vinkemeier, U., Zhao, Y., Jeruzalmi, D., Darnell, J. E., Jr., and Kuriyan, J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell, 93: 827-839, 1998.
    • (1998) Cell , vol.93 , pp. 827-839
    • Chen, X.1    Vinkemeier, U.2    Zhao, Y.3    Jeruzalmi, D.4    Darnell J.E., Jr.5    Kuriyan, J.6
  • 45
    • 0033621066 scopus 로고    scopus 로고
    • A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1
    • Haspel, R. L., and Darnell, J. E., Jr. A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1. Proc. Natl. Acad. Sci. USA, 96: 10188-10193, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10188-10193
    • Haspel, R.L.1    Darnell J.E., Jr.2
  • 46
    • 0032499801 scopus 로고    scopus 로고
    • Three-dimensional structure of the Stat3β homodimer bound to DNA
    • Becker, S., Groner, B., and Muller, C. W. Three-dimensional structure of the Stat3β homodimer bound to DNA. Nature (Lond.), 394: 145-151, 1998.
    • (1998) Nature (Lond.) , vol.394 , pp. 145-151
    • Becker, S.1    Groner, B.2    Muller, C.W.3
  • 47
    • 0029903770 scopus 로고    scopus 로고
    • DNA binding of in vitro activated Stat1 α, Stat1 β and truncated Stat1: Interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites
    • Vinkemeier, U., Cohen, S. L., Moarefi, I., Chait, B. T., Kuriyan, J., and Darnell, J. E., Jr. DNA binding of in vitro activated Stat1 α, Stat1 β and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J., 15: 5616-5626, 1996.
    • (1996) EMBO J. , vol.15 , pp. 5616-5626
    • Vinkemeier, U.1    Cohen, S.L.2    Moarefi, I.3    Chait, B.T.4    Kuriyan, J.5    Darnell J.E., Jr.6
  • 49
    • 0028349904 scopus 로고
    • Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
    • Shuai, K., Horvath, C. M., Huang, L. H., Qureshi, S. A., Cowburn, D., and Darnell, J. E., Jr. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell, 76: 821-828, 1994.
    • (1994) Cell , vol.76 , pp. 821-828
    • Shuai, K.1    Horvath, C.M.2    Huang, L.H.3    Qureshi, S.A.4    Cowburn, D.5    Darnell J.E., Jr.6
  • 50
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen, Z., Zhong, Z., and Darnell, J. E., Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell. 82: 241-250, 1995.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell J.E., Jr.3
  • 55
    • 0033214903 scopus 로고    scopus 로고
    • Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3
    • Chapman, R. S., Lourenco, P. C., Tonner, E., Flint, D. J., Selbert, S., Takeda, K., Akira, S., Clarke, A. R., and Watson, C. J. Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. Genes Dev., 13: 2604-2616, 1999.
    • (1999) Genes Dev. , vol.13 , pp. 2604-2616
    • Chapman, R.S.1    Lourenco, P.C.2    Tonner, E.3    Flint, D.J.4    Selbert, S.5    Takeda, K.6    Akira, S.7    Clarke, A.R.8    Watson, C.J.9
  • 56
    • 0033198793 scopus 로고    scopus 로고
    • Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
    • Sano, S., Itami, S., Takeda, K., Tarutani, M., Yamaguchi, Y., Miura, H., Yoshikawa, K., Akira, S., and Takeda, J. Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J., 18: 4657-4668, 1999.
    • (1999) EMBO J. , vol.18 , pp. 4657-4668
    • Sano, S.1    Itami, S.2    Takeda, K.3    Tarutani, M.4    Yamaguchi, Y.5    Miura, H.6    Yoshikawa, K.7    Akira, S.8    Takeda, J.9
  • 57
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
    • Takeda, K., Clausen, B. E., Kaisho, T., Tsujimura, T., Terada, N., Forster, I., and Akira, S. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity, 10: 39-49, 1999.
    • (1999) Immunity , vol.10 , pp. 39-49
    • Takeda, K.1    Clausen, B.E.2    Kaisho, T.3    Tsujimura, T.4    Terada, N.5    Forster, I.6    Akira, S.7
  • 59
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu, C. L., Meyer, D. J., Campbell, G. S., Lamer, A. C., Carter-Su, C., Schwartz, J., and Jove, R. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science (Wash. DC), 269: 81-83, 1995.
    • (1995) Science (Wash. DC) , vol.269 , pp. 81-83
    • Yu, C.L.1    Meyer, D.J.2    Campbell, G.S.3    Lamer, A.C.4    Carter-Su, C.5    Schwartz, J.6    Jove, R.7
  • 60
    • 0029916933 scopus 로고    scopus 로고
    • Activation and association of Stat3 with Src in v-Src-transformed cell lines
    • Cao, X., Tay, A., Guy, G. R., and Tan, Y. H. Activation and association of Stat3 with Src in v-Src-transformed cell lines. Mol. Cell. Biol., 16: 1595-1603, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1595-1603
    • Cao, X.1    Tay, A.2    Guy, G.R.3    Tan, Y.H.4
  • 61
    • 0030992813 scopus 로고    scopus 로고
    • Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs
    • Chaturvedi, P., Sharma, S., and Reddy, E. P. Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs. Mol. Cell. Biol., 17: 3295-3304, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3295-3304
    • Chaturvedi, P.1    Sharma, S.2    Reddy, E.P.3
  • 63
    • 0031953831 scopus 로고    scopus 로고
    • Stat3 activation by Src induces specific gene regulation and is required for cell transformation
    • Turkson, J., Bowman, T., Garcia, R., Caldenhoven, E., De Groot, R. P., and Jove, R. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol. Cell. Biol., 18: 2545-2552, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 64
    • 0030034383 scopus 로고    scopus 로고
    • Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines
    • Chiu, J. J., Sgagias, M. K., and Cowan, K. H. Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines. Clin. Cancer Res., 2: 215-221, 1996.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 215-221
    • Chiu, J.J.1    Sgagias, M.K.2    Cowan, K.H.3
  • 66
    • 0033548431 scopus 로고    scopus 로고
    • Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption
    • Park, S. H., Liu, X., Hennighausen, L., Davey, H. W., and Waxman, D. J. Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption. J. Biol. Chem., 274: 7421-7430, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7421-7430
    • Park, S.H.1    Liu, X.2    Hennighausen, L.3    Davey, H.W.4    Waxman, D.J.5
  • 68
    • 0033597715 scopus 로고    scopus 로고
    • Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: A direct role for Stat5 in Bcl-X(L) induction
    • Socolovsky, M., Fallon, A. E., Wang, S., Brugnara, C., and Lodish, H. F. Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell, 98: 181-191, 1999.
    • (1999) Cell , vol.98 , pp. 181-191
    • Socolovsky, M.1    Fallon, A.E.2    Wang, S.3    Brugnara, C.4    Lodish, H.F.5
  • 69
    • 0028217452 scopus 로고
    • Mammary gland factor (MGF) is a novel member of the cytokine-regulated transcription factor gene family and confers the prolactin response
    • Wakao, H., Gouilleux, F., and Groner, B. Mammary gland factor (MGF) is a novel member of the cytokine-regulated transcription factor gene family and confers the prolactin response. EMBO J., 13: 2182-2191, 1994.
    • (1994) EMBO J. , vol.13 , pp. 2182-2191
    • Wakao, H.1    Gouilleux, F.2    Groner, B.3
  • 71
    • 0033180185 scopus 로고    scopus 로고
    • Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells
    • Moriggl, R., Sexl, V., Piekorz, R., Topham, D., and Ihle, J. N. Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells. Immunity, 11: 225-230, 1999.
    • (1999) Immunity , vol.11 , pp. 225-230
    • Moriggl, R.1    Sexl, V.2    Piekorz, R.3    Topham, D.4    Ihle, J.N.5
  • 73
    • 0031836964 scopus 로고    scopus 로고
    • Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
    • Onishi, M., Nosaka, T., Misawa, K., Mui, A. L., Gorman, D., McMahon, M., Miyajima, A., and Kitamura, T. Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol. Cell. Biol., 18: 3871-3879, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3871-3879
    • Onishi, M.1    Nosaka, T.2    Misawa, K.3    Mui, A.L.4    Gorman, D.5    McMahon, M.6    Miyajima, A.7    Kitamura, T.8
  • 74
    • 0029810923 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
    • Shuai, K., Halpern, J., ten Hoeve, J., Rao, X., and Sawyers, C. L. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia. Oncogene, 13: 247-254, 1996.
    • (1996) Oncogene , vol.13 , pp. 247-254
    • Shuai, K.1    Halpern, J.2    Ten Hoeve, J.3    Rao, X.4    Sawyers, C.L.5
  • 75
    • 0022859356 scopus 로고
    • Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome
    • Mes-Masson, A. M., McLaughlin, J., Daley, G. Q., Paskind, M., and Witte, O. N. Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome. Proc. Natl. Acad. Sci. USA, 83: 9768-9772, 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9768-9772
    • Mes-Masson, A.M.1    McLaughlin, J.2    Daley, G.Q.3    Paskind, M.4    Witte, O.N.5
  • 76
    • 0025766195 scopus 로고
    • BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a nonphosphotyrosine-dependent manner
    • Pendergast, A. M., Muller, A. J., Havlik, M. H., Maru, Y., and Witte, O. N. BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a nonphosphotyrosine-dependent manner. Cell, 66: 161-171, 1991.
    • (1991) Cell , vol.66 , pp. 161-171
    • Pendergast, A.M.1    Muller, A.J.2    Havlik, M.H.3    Maru, Y.4    Witte, O.N.5
  • 77
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo, T. G., Pendergast, A. M., Muller, A. J., and Witte, O. N. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science (Wash. DC), 247: 1079-1082, 1990.
    • (1990) Science (Wash. DC) , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 78
    • 0034653929 scopus 로고    scopus 로고
    • STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells
    • Sillaber, C., Gesbert, F., Frank, D. A., Sattler, M., and Griffin, J. D. STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells. Blood, 95: 2118-2125, 2000.
    • (2000) Blood , vol.95 , pp. 2118-2125
    • Sillaber, C.1    Gesbert, F.2    Frank, D.A.3    Sattler, M.4    Griffin, J.D.5
  • 79
    • 0033178667 scopus 로고    scopus 로고
    • STAT5 activation by BCR-Abl contributes to transformation of K562 leukemia cells
    • de Groot, R. P., Raaijmakers, J. A., Lammers, J. W., Jove, R., and Koenderman, L. STAT5 activation by BCR-Abl contributes to transformation of K562 leukemia cells. Blood, 94: 1108-1112, 1999.
    • (1999) Blood , vol.94 , pp. 1108-1112
    • De Groot, R.P.1    Raaijmakers, J.A.2    Lammers, J.W.3    Jove, R.4    Koenderman, L.5
  • 80
    • 0033583530 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis
    • Nieborowska-Skorska, M., Wasik, M. A., Slupianek, A., Salomoni, P., Kitamura, T., Calabretta, B., and Skorski, T. Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis. J. Exp. Med., 189: 1229-1242, 1999.
    • (1999) J. Exp. Med. , vol.189 , pp. 1229-1242
    • Nieborowska-Skorska, M.1    Wasik, M.A.2    Slupianek, A.3    Salomoni, P.4    Kitamura, T.5    Calabretta, B.6    Skorski, T.7
  • 81
    • 0028817880 scopus 로고
    • Jak-Stat signaling induced by the v-Abl oncogene
    • Danial, N. N., Pernis, A., and Rothman, P. B. Jak-Stat signaling induced by the v-Abl oncogene. Science (Wash. DC), 269: 1875-1877, 1995.
    • (1995) Science (Wash. DC) , vol.269 , pp. 1875-1877
    • Danial, N.N.1    Pernis, A.2    Rothman, P.B.3
  • 83
    • 0034660853 scopus 로고    scopus 로고
    • STAT5 activation is required for interleukin-9-dependent growth and transformation of lymphoid cells
    • Demoulin, J. B., Uyttenhove, C., Lejeune, D., Mui, A., Groner, B., and Renauld, J. C. STAT5 activation is required for interleukin-9-dependent growth and transformation of lymphoid cells. Cancer Res., 60: 3971-3977, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 3971-3977
    • Demoulin, J.B.1    Uyttenhove, C.2    Lejeune, D.3    Mui, A.4    Groner, B.5    Renauld, J.C.6
  • 85
    • 0034665780 scopus 로고    scopus 로고
    • Bcr/Abl activates transcription of the Bcl-X gene through STAT5
    • Gesbert, F., and Griffin, J. D. Bcr/Abl activates transcription of the Bcl-X gene through STAT5. Blood, 96: 2269-2276, 2000.
    • (2000) Blood , vol.96 , pp. 2269-2276
    • Gesbert, F.1    Griffin, J.D.2
  • 86
    • 0033584297 scopus 로고    scopus 로고
    • Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors
    • Karni, R., Jove, R., and Levitzki, A. Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors. Oncogene, 18: 4654-4662, 1999.
    • (1999) Oncogene , vol.18 , pp. 4654-4662
    • Karni, R.1    Jove, R.2    Levitzki, A.3
  • 87
    • 0031034078 scopus 로고    scopus 로고
    • Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions
    • Zhou, P., Qian, L., Kozopas, K. M., and Craig, R. W. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood, 89: 630-643, 1997.
    • (1997) Blood , vol.89 , pp. 630-643
    • Zhou, P.1    Qian, L.2    Kozopas, K.M.3    Craig, R.W.4
  • 88
    • 0035876931 scopus 로고    scopus 로고
    • Cooperative regulation of Mcl-1 by Janus kinase/Stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils
    • Epling-Burnette, P. K., Zhong, B., Bai, F., Jiang, K., Bailey, R. D., Garcia, R., Jove, R., Djeu, J. Y., Loughran, T. P., Jr., and Wei, S. Cooperative regulation of Mcl-1 by Janus kinase/Stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils. J. Immunol., 166: 7486-7495, 2001.
    • (2001) J. Immunol. , vol.166 , pp. 7486-7495
    • Epling-Burnette, P.K.1    Zhong, B.2    Bai, F.3    Jiang, K.4    Bailey, R.D.5    Garcia, R.6    Jove, R.7    Djeu, J.Y.8    Loughran T.P., Jr.9    Wei, S.10
  • 89
    • 0034163579 scopus 로고    scopus 로고
    • The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the transactivation domain of Stat5
    • Lord, J. D., McIntosh, B. C., Greenberg, P. D., and Nelson, B. H. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the transactivation domain of Stat5. J. Immunol., 164: 2533-2541, 2000.
    • (2000) J. Immunol. , vol.164 , pp. 2533-2541
    • Lord, J.D.1    McIntosh, B.C.2    Greenberg, P.D.3    Nelson, B.H.4
  • 91
    • 0034676267 scopus 로고    scopus 로고
    • Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling
    • Sinibaldi, D., Wharton, W., Turkson, J., Bowman, T., Pledger, W. J., and Jove, R. Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene, 19: 5419-5427, 2000.
    • (2000) Oncogene , vol.19 , pp. 5419-5427
    • Sinibaldi, D.1    Wharton, W.2    Turkson, J.3    Bowman, T.4    Pledger, W.J.5    Jove, R.6
  • 92
    • 0035253352 scopus 로고    scopus 로고
    • Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2
    • Martino, A., Holmes, J. H., IV, Lord, J. D., Moon, J. J., and Nelson, B. H. Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2. J. Immunol., 166: 1723-1729, 2001.
    • (2001) J. Immunol. , vol.166 , pp. 1723-1729
    • Martino, A.1    Holmes J.H. IV2    Lord, J.D.3    Moon, J.J.4    Nelson, B.H.5
  • 93
    • 0034657917 scopus 로고    scopus 로고
    • Modulation of STAT signaling by STAT-interacting proteins
    • Shuai, K. Modulation of STAT signaling by STAT-interacting proteins. Oncogene, 19: 2638-2644, 2000.
    • (2000) Oncogene , vol.19 , pp. 2638-2644
    • Shuai, K.1
  • 94
    • 0034841006 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling
    • Greenhalgh, C. J., and Hilton, D. J. Negative regulation of cytokine signaling. J. Leukocyte Biol., 70: 348-356, 2001.
    • (2001) J. Leukocyte Biol. , vol.70 , pp. 348-356
    • Greenhalgh, C.J.1    Hilton, D.J.2
  • 95
    • 0032966863 scopus 로고    scopus 로고
    • Negative regulation of the JAK/STAT pathway
    • Starr, R., and Hilton, D. J. Negative regulation of the JAK/STAT pathway. Bioessays, 21: 47-52, 1999.
    • (1999) Bioessays , vol.21 , pp. 47-52
    • Starr, R.1    Hilton, D.J.2
  • 98
    • 0035036625 scopus 로고    scopus 로고
    • Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
    • Frantsve, J., Schwaller, J., Sternberg, D. W., Kutok, J., and Gilliland, D. G. Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation. Mol. Cell. Biol., 21: 3547-3557, 2001.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3547-3557
    • Frantsve, J.1    Schwaller, J.2    Sternberg, D.W.3    Kutok, J.4    Gilliland, D.G.5
  • 99
    • 0032706054 scopus 로고    scopus 로고
    • Localization of a target region of allelic loss to a 1-cM interval on chromosome 16p.13.13 in hepatocellular carcinoma
    • Koyama, M., Nagai, H., Bando, K., Ito, M., Moriyama, Y., and Emi, M. Localization of a target region of allelic loss to a 1-cM interval on chromosome 16p.13.13 in hepatocellular carcinoma. Jpn. J. Cancer Res., 90: 951-956, 1999.
    • (1999) Jpn. J. Cancer Res. , vol.90 , pp. 951-956
    • Koyama, M.1    Nagai, H.2    Bando, K.3    Ito, M.4    Moriyama, Y.5    Emi, M.6
  • 102
    • 0030986236 scopus 로고    scopus 로고
    • A signature motif in transcriptional coactivators mediates binding to nuclear receptors
    • Heery, D. M., Kalkhoven, E., Hoare, S., and Parker, M. G. A signature motif in transcriptional coactivators mediates binding to nuclear receptors. Nature (Lond.), 387: 733-736, 1997.
    • (1997) Nature (Lond.) , vol.387 , pp. 733-736
    • Heery, D.M.1    Kalkhoven, E.2    Hoare, S.3    Parker, M.G.4
  • 103
    • 0034624877 scopus 로고    scopus 로고
    • Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction
    • Liao, J., Fu, Y., and Shuai, K. Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction. Proc. Natl. Acad. Sci. USA, 97: 5267-5272, 2000.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5267-5272
    • Liao, J.1    Fu, Y.2    Shuai, K.3
  • 104
    • 0035943676 scopus 로고    scopus 로고
    • Activation of estrogen receptor blocks interleukin-6-inducible cell growth of human multiple myeloma involving molecular cross-talk between estrogen receptor and STAT3 mediated by coregulator PIAS3
    • Wang, L. H., Yang, X. Y., Mihalic, K., Xiao, W., Li, D., and Farrar, W. L. Activation of estrogen receptor blocks interleukin-6-inducible cell growth of human multiple myeloma involving molecular cross-talk between estrogen receptor and STAT3 mediated by coregulator PIAS3. J. Biol. Chem., 276: 31839-31844, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31839-31844
    • Wang, L.H.1    Yang, X.Y.2    Mihalic, K.3    Xiao, W.4    Li, D.5    Farrar, W.L.6
  • 106
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker, T., and Kovarik, P. Serine phosphorylation of STATs. Oncogene, 19: 2628-2637, 2000.
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 107
    • 0032746702 scopus 로고    scopus 로고
    • Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein
    • Turkson, J., Bowman, T., Adnane, J., Zhang, Y., Djeu, J., Sekharam, M., Frank, D. A., Holzman, L. B., Wu, J., Sebti, S., and Jove, R. Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein. Mol. Cell. Biol., 19: 7519-7528, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7519-7528
    • Turkson, J.1    Bowman, T.2    Adnane, J.3    Zhang, Y.4    Djeu, J.5    Sekharam, M.6    Frank, D.A.7    Holzman, L.B.8    Wu, J.9    Sebti, S.10    Jove, R.11
  • 108
    • 0034677755 scopus 로고    scopus 로고
    • Mechanism-based target identification and drug discovery in cancer research
    • Gibbs, J. B. Mechanism-based target identification and drug discovery in cancer research. Science (Wash. DC), 287: 1969-1973, 2000.
    • (2000) Science (Wash. DC) , vol.287 , pp. 1969-1973
    • Gibbs, J.B.1
  • 109
    • 0032718891 scopus 로고    scopus 로고
    • Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
    • Niu, G., Heller, R., Catlett-Falcone, R., Coppola, D., Jaroszeski, M., Dalton, W., Jove, R., and Yu, H. Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res., 59: 5059-5063, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 5059-5063
    • Niu, G.1    Heller, R.2    Catlett-Falcone, R.3    Coppola, D.4    Jaroszeski, M.5    Dalton, W.6    Jove, R.7    Yu, H.8
  • 110
    • 0033061032 scopus 로고    scopus 로고
    • Protein tyrosine kinase inhibitors as novel therapeutic agents
    • Levitzki, A. Protein tyrosine kinase inhibitors as novel therapeutic agents. Pharmacol. Ther., 82: 231-239, 1999.
    • (1999) Pharmacol. Ther. , vol.82 , pp. 231-239
    • Levitzki, A.1
  • 111
    • 0035870249 scopus 로고    scopus 로고
    • Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
    • Niu, G., Shain, K. H., Huang, M., Ravi, R., Bedi, A., Dalton, W. S., Jove, R., and Yu, H. Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest. Cancer Res., 61: 3276-3280, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3276-3280
    • Niu, G.1    Shain, K.H.2    Huang, M.3    Ravi, R.4    Bedi, A.5    Dalton, W.S.6    Jove, R.7    Yu, H.8
  • 112
    • 0034658111 scopus 로고    scopus 로고
    • Pharmaceutical intervention in the JAK/STAT signaling pathway
    • Seidel, H. M., Lamb, P., and Rosen, J. Pharmaceutical intervention in the JAK/STAT signaling pathway. Oncogene, 19: 2645-2656, 2000.
    • (2000) Oncogene , vol.19 , pp. 2645-2656
    • Seidel, H.M.1    Lamb, P.2    Rosen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.