-
1
-
-
0024616167
-
Molecular interactions in macrophage activation
-
Adams, D. O. (1989) Molecular interactions in macrophage activation. Immunol. Today 10, 33-35.
-
(1989)
Immunol. Today
, vol.10
, pp. 33-35
-
-
Adams, D.O.1
-
2
-
-
0021018773
-
Immune interferon and leukocyte-conditioned medium induce normal and leukemic myeloid cells to differentiate along the monocytic pathway
-
Perussia, B., Dayton, E. T., Fanning, V., Thiagarajan, P., Hoxie, J., Trinchieri, G. (1983) Immune interferon and leukocyte-conditioned medium induce normal and leukemic myeloid cells to differentiate along the monocytic pathway. J. Exp. Med. 158, 2058-2080.
-
(1983)
J. Exp. Med.
, vol.158
, pp. 2058-2080
-
-
Perussia, B.1
Dayton, E.T.2
Fanning, V.3
Thiagarajan, P.4
Hoxie, J.5
Trinchieri, G.6
-
3
-
-
0028848472
-
Role of interferon-gamma in immune cell regulation
-
Young, H. A., Hardy, K. J. (1995) Role of interferon-gamma in immune cell regulation. J. Leukoc. Biol. 58, 373-381.
-
(1995)
J. Leukoc. Biol.
, vol.58
, pp. 373-381
-
-
Young, H.A.1
Hardy, K.J.2
-
4
-
-
0030890586
-
Cellular responses to interferon-gamma
-
Boehm, U., Klamp, T., Groot, M., Howard, J. C. (1997) Cellular responses to interferon-gamma. Annu. Rev. Immunol. 15, 749-795.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 749-795
-
-
Boehm, U.1
Klamp, T.2
Groot, M.3
Howard, J.C.4
-
5
-
-
0032729476
-
Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells
-
Carnaud, C., Lee, D., Donnars, O., Park, S. H., Beavis, A., Koezuka, Y., Bendelac, A. (1999) Cutting edge: cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J. Immunol. 163, 4647-4650.
-
(1999)
J. Immunol.
, vol.163
, pp. 4647-4650
-
-
Carnaud, C.1
Lee, D.2
Donnars, O.3
Park, S.H.4
Beavis, A.5
Koezuka, Y.6
Bendelac, A.7
-
6
-
-
0023839463
-
IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses
-
Finkelman, F. D., Katona, I. M., Mosmann, T. R., Coffman, R. L. (1988) IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. J. Immunol. 140, 1022-1027.
-
(1988)
J. Immunol.
, vol.140
, pp. 1022-1027
-
-
Finkelman, F.D.1
Katona, I.M.2
Mosmann, T.R.3
Coffman, R.L.4
-
8
-
-
0030889207
-
The IFN gamma receptor: A paradigm for cytokine receptor signaling
-
Bach, E. A., Aguet, M., Schreiber, R. D. (1997) The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol. 15, 563-591.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 563-591
-
-
Bach, E.A.1
Aguet, M.2
Schreiber, R.D.3
-
9
-
-
0035134688
-
Interferon in oncological practice: Review of interferon biology, clinical applications, and toxicities
-
Jonasch, E., Haluska, F. G. (2001) Interferon in oncological practice: review of interferon biology, clinical applications, and toxicities. Oncologist 6, 34-55.
-
(2001)
Oncologist
, vol.6
, pp. 34-55
-
-
Jonasch, E.1
Haluska, F.G.2
-
10
-
-
0030976772
-
Interferon tau: A novel pregnancy recognition signal
-
Bazer, F. W., Spencer, T. E., Ott, T. L. (1997) Interferon tau: a novel pregnancy recognition signal. Am. J. Reprod. Immunol. 37, 412-420.
-
(1997)
Am. J. Reprod. Immunol.
, vol.37
, pp. 412-420
-
-
Bazer, F.W.1
Spencer, T.E.2
Ott, T.L.3
-
11
-
-
0029819030
-
Regulation of interferon-gamma gene expression
-
Young, H. A. (1996) Regulation of interferon-gamma gene expression. J. Interferon Cytokine Res. 16, 563-568.
-
(1996)
J. Interferon Cytokine Res.
, vol.16
, pp. 563-568
-
-
Young, H.A.1
-
12
-
-
0035472079
-
IFN-gamma production by antigen-presenting cells: Mechanisms emerge
-
Frucht, D. M., Fukao, T., Bogdan, C., Schindler, H., O'Shea, J. J., Koyasu, S. (2001) IFN-gamma production by antigen-presenting cells: mechanisms emerge. Trends Immunol. 22, 556-560.
-
(2001)
Trends Immunol.
, vol.22
, pp. 556-560
-
-
Frucht, D.M.1
Fukao, T.2
Bogdan, C.3
Schindler, H.4
O'Shea, J.J.5
Koyasu, S.6
-
13
-
-
0344193087
-
IFN-gamma expression in macrophages and its possible biological significance
-
Gessani, S., Belardelli, F. (1998) IFN-gamma expression in macrophages and its possible biological significance. Cytokine Growth Factor Rev. 9, 117-123.
-
(1998)
Cytokine Growth Factor Rev.
, vol.9
, pp. 117-123
-
-
Gessani, S.1
Belardelli, F.2
-
14
-
-
0032193770
-
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-gamma production
-
Yoshimoto, T., Takeda, K., Tanaka, T., Ohkusu, K., Kashiwamura, S., Okamura, H., Akira, S., Nakanishi, K. (1998) IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J. Immunol. 161, 3400-3407.
-
(1998)
J. Immunol.
, vol.161
, pp. 3400-3407
-
-
Yoshimoto, T.1
Takeda, K.2
Tanaka, T.3
Ohkusu, K.4
Kashiwamura, S.5
Okamura, H.6
Akira, S.7
Nakanishi, K.8
-
15
-
-
0034613687
-
Autocrine secretion of interferon gamma negatively regulates homing of immature B cells
-
Flaishon, L., Hershkoviz, R., Lantner, F., Lider, O., Alon, R., Levo, Y., Flavell, R. A., Shachar, I. (2000) Autocrine secretion of interferon gamma negatively regulates homing of immature B cells. J. Exp. Med. 192, 1381-1388.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1381-1388
-
-
Flaishon, L.1
Hershkoviz, R.2
Lantner, F.3
Lider, O.4
Alon, R.5
Levo, Y.6
Flavell, R.A.7
Shachar, I.8
-
16
-
-
0034568991
-
Reciprocal regulation of polarized cytokine production by effector B and T cells
-
Harris, D. P., Haynes, L., Sayles, P. C., Duso, D. K., Eaton, S. M., Lepak, N. M., Johnson, L. L., Swain, S. L., Lund, F. E. (2000) Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat. Immunol. 1, 475-482.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 475-482
-
-
Harris, D.P.1
Haynes, L.2
Sayles, P.C.3
Duso, D.K.4
Eaton, S.M.5
Lepak, N.M.6
Johnson, L.L.7
Swain, S.L.8
Lund, F.E.9
-
17
-
-
0034769960
-
Viruses and interferons
-
Sen, G. C. (2001) Viruses and interferons. Annu. Rev. Microbiol. 55, 255-281.
-
(2001)
Annu. Rev. Microbiol.
, vol.55
, pp. 255-281
-
-
Sen, G.C.1
-
18
-
-
0034213540
-
Direct stimulation of macrophages by IL-12 and IL-18-a bridge too far?
-
Golab, J., Zagozdzon, Stoklosal, T., Kaminski, R., Kozar, K., Jakohisiak, M. (2000) Direct stimulation of macrophages by IL-12 and IL-18-a bridge too far? Immunol. Lett. 72, 153-157.
-
(2000)
Immunol. Lett.
, vol.72
, pp. 153-157
-
-
Golab, J.1
Zagozdzon2
Stoklosal, T.3
Kaminski, R.4
Kozar, K.5
Jakohisiak, M.6
-
19
-
-
0035201197
-
Direct stimulation of macrophages by IL-12 and IL-18-a bridge built on solid ground
-
Munder, M., Mallo, M., Eichmann, K., Modolell, M. (2001) Direct stimulation of macrophages by IL-12 and IL-18-a bridge built on solid ground. Immunol. Lett. 75, 159-160.
-
(2001)
Immunol. Lett.
, vol.75
, pp. 159-160
-
-
Munder, M.1
Mallo, M.2
Eichmann, K.3
Modolell, M.4
-
20
-
-
0032526840
-
Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation
-
Munder, M., Mallo, M., Eichmann, K., Modolell, M. (1998) Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J. Exp. Med. 187, 2103-2108.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2103-2108
-
-
Munder, M.1
Mallo, M.2
Eichmann, K.3
Modolell, M.4
-
21
-
-
0033970867
-
Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN-gamma production by dendritic cells
-
Fukao, T., Matsuda, S., Koyasu, S. (2000) Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN-gamma production by dendritic cells. J. Immunol. 164, 64-71.
-
(2000)
J. Immunol.
, vol.164
, pp. 64-71
-
-
Fukao, T.1
Matsuda, S.2
Koyasu, S.3
-
22
-
-
0033381309
-
Identification of IFN-gamma-producing cells in IL-12/IL-18-treated mice
-
Otani, T., Nakamura, S., Toki, M., Motoda, R., Kurimoto, M., Orita, K. (1999) Identification of IFN-gamma-producing cells in IL-12/IL-18-treated mice. Cell. Immunol. 198, 111-119.
-
(1999)
Cell. Immunol.
, vol.198
, pp. 111-119
-
-
Otani, T.1
Nakamura, S.2
Toki, M.3
Motoda, R.4
Kurimoto, M.5
Orita, K.6
-
23
-
-
0033952638
-
The role of IL-18 in innate immunity
-
Akira, S. (2000) The role of IL-18 in innate immunity. Curr. Opin. Immunol. 12, 59-63.
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 59-63
-
-
Akira, S.1
-
24
-
-
0032607876
-
IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family
-
Dinarello, C. A. (1999) IL-18: a TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J. Allergy Clin. Immunol. 103, 11-24.
-
(1999)
J. Allergy Clin. Immunol.
, vol.103
, pp. 11-24
-
-
Dinarello, C.A.1
-
25
-
-
0034045085
-
A chemokine-to-cytokine-to-chemokine cascade critical in antiviral defense
-
Salazar-Mather, T. P., Hamilton, T. A., Biron, C. A. (2000) A chemokine-to-cytokine-to-chemokine cascade critical in antiviral defense. J. Clin. Invest. 105, 985-993.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 985-993
-
-
Salazar-Mather, T.P.1
Hamilton, T.A.2
Biron, C.A.3
-
26
-
-
0034327172
-
Cutting edge: Selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection
-
Pien, G. C., Satoskar, A. R., Takeda, K., Akira, S., Biron, C. A. (2000) Cutting edge: selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection. J. Immunol. 165, 4787-4791.
-
(2000)
J. Immunol.
, vol.165
, pp. 4787-4791
-
-
Pien, G.C.1
Satoskar, A.R.2
Takeda, K.3
Akira, S.4
Biron, C.A.5
-
27
-
-
0035284905
-
The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4
-
Schindler, H., Lutz, M. B., Rollinghoff, M., Bogdan, C. (2001) The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4. J. Immunol. 166, 3075-3082.
-
(2001)
J. Immunol.
, vol.166
, pp. 3075-3082
-
-
Schindler, H.1
Lutz, M.B.2
Rollinghoff, M.3
Bogdan, C.4
-
28
-
-
0035313545
-
Inducible expression of Stat4 in dendritic cells and macrophages and its critical role in innate and adaptive immune responses
-
Fukao, T., Frucht, D. M., Yap, G., Gadina, M., O'Shea, J. J., Koyasu, S. (2001) Inducible expression of Stat4 in dendritic cells and macrophages and its critical role in innate and adaptive immune responses. J. Immunol. 166, 4446-4455.
-
(2001)
J. Immunol.
, vol.166
, pp. 4446-4455
-
-
Fukao, T.1
Frucht, D.M.2
Yap, G.3
Gadina, M.4
O'Shea, J.J.5
Koyasu, S.6
-
29
-
-
0035339882
-
Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets
-
Hochrein, H., Shortman, K., Vremec, D., Scott, B., Hertzog, P., O'Keeffe, M. (2001) Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets. J. Immunol. 166, 5448-5455.
-
(2001)
J. Immunol.
, vol.166
, pp. 5448-5455
-
-
Hochrein, H.1
Shortman, K.2
Vremec, D.3
Scott, B.4
Hertzog, P.5
O'Keeffe, M.6
-
30
-
-
0030243473
-
Effects of the route of infection on immunoglobulin G subclasses and specificity of the reovirus-specific humoral immune response
-
Major, A. S., Cuff, C. F. (1996) Effects of the route of infection on immunoglobulin G subclasses and specificity of the reovirus-specific humoral immune response. J. Virol. 70, 5968-5974.
-
(1996)
J. Virol.
, vol.70
, pp. 5968-5974
-
-
Major, A.S.1
Cuff, C.F.2
-
31
-
-
0028120945
-
Desferrioxamine-promoted virulence of Yersinia enterocolitica in mice depends on both desferrioxamine type and mouse strain
-
Autenrieth, I. B., Reissbrodt, R., Saken, E., Berner, R., Vogel, U., Rabsch, W., Heesemann, J. (1994) Desferrioxamine-promoted virulence of Yersinia enterocolitica in mice depends on both desferrioxamine type and mouse strain. J. Infect. Dis. 169, 562-567.
-
(1994)
J. Infect. Dis.
, vol.169
, pp. 562-567
-
-
Autenrieth, I.B.1
Reissbrodt, R.2
Saken, E.3
Berner, R.4
Vogel, U.5
Rabsch, W.6
Heesemann, J.7
-
32
-
-
0028242631
-
Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: An essential role for gamma interferon
-
Autenrieth, I. B., Beer, M., Bohn, E., Kaufmann, S. H., Heesemann, J. (1994) Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: an essential role for gamma interferon. Infect. Immun. 62, 2590-2599.
-
(1994)
Infect. Immun.
, vol.62
, pp. 2590-2599
-
-
Autenrieth, I.B.1
Beer, M.2
Bohn, E.3
Kaufmann, S.H.4
Heesemann, J.5
-
33
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan, J. F. (1990) Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. USA 87, 6934-6938.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
34
-
-
0025755810
-
Structural symmetry of the extracellular domain of the cytokine/growth hormone/prolactin receptor family and interferon receptors revealed by hydrophobic cluster analysis
-
Thoreau, E., Petridou, B., Kelly, P. A., Djiane, J., Mornon, J. P. (1991) Structural symmetry of the extracellular domain of the cytokine/growth hormone/prolactin receptor family and interferon receptors revealed by hydrophobic cluster analysis. FEBS Lett. 282, 26-31.
-
(1991)
FEBS Lett.
, vol.282
, pp. 26-31
-
-
Thoreau, E.1
Petridou, B.2
Kelly, P.A.3
Djiane, J.4
Mornon, J.P.5
-
35
-
-
0035216135
-
Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death
-
Bernabei, P., Coccia, E. M., Rigamonti, L., Bosticardo, M., Forni, G., Pestka, S., Krause, C. D., Battistini, A., Novelli, F. (2001) Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death. J. Leukoc. Biol. 70, 950-960.
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 950-960
-
-
Bernabei, P.1
Coccia, E.M.2
Rigamonti, L.3
Bosticardo, M.4
Forni, G.5
Pestka, S.6
Krause, C.D.7
Battistini, A.8
Novelli, F.9
-
36
-
-
0029015464
-
Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells
-
Pernis, A., Gupta, S., Gollob, K. J., Garfein, E., Coffman, R. L., Schindler, C., Rothman, P. (1995) Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells. Science 269, 245-247.
-
(1995)
Science
, vol.269
, pp. 245-247
-
-
Pernis, A.1
Gupta, S.2
Gollob, K.J.3
Garfein, E.4
Coffman, R.L.5
Schindler, C.6
Rothman, P.7
-
37
-
-
0028972504
-
Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets
-
Bach, E. A., Szabo, S. J., Dighe, A. S., Ashkenazi, A., Aguet, M., Murphy, K. M., Schreiber, R. D. (1995) Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets. Science 270, 1215-1218.
-
(1995)
Science
, vol.270
, pp. 1215-1218
-
-
Bach, E.A.1
Szabo, S.J.2
Dighe, A.S.3
Ashkenazi, A.4
Aguet, M.5
Murphy, K.M.6
Schreiber, R.D.7
-
38
-
-
0026507228
-
Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones
-
Maggi, E., Parronchi, P., Manetti, R., Simonelli, C., Piccinni, M. P., Rugiu, F. S., De Carli, M., Ricci, M., Romagnani, S. (1992) Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones. J. Immunol. 148, 2142-2147.
-
(1992)
J. Immunol.
, vol.148
, pp. 2142-2147
-
-
Maggi, E.1
Parronchi, P.2
Manetti, R.3
Simonelli, C.4
Piccinni, M.P.5
Rugiu, F.S.6
De Carli, M.7
Ricci, M.8
Romagnani, S.9
-
39
-
-
0023726937
-
Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clone
-
Gajewski, T. F., Fitch, F. W. (1988) Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clone. J. Immunol. 140, 4245-4252.
-
(1988)
J. Immunol.
, vol.140
, pp. 4245-4252
-
-
Gajewski, T.F.1
Fitch, F.W.2
-
40
-
-
0029671421
-
Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding
-
Kaplan, D. H., Greenlund, A. C., Tanner, J. W., Shaw, A. S., Schreiber, R. D. (1996) Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding. J. Biol. Chem. 271, 9-12.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9-12
-
-
Kaplan, D.H.1
Greenlund, A.C.2
Tanner, J.W.3
Shaw, A.S.4
Schreiber, R.D.5
-
41
-
-
0028175454
-
Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)
-
Greenlund, A. C., Farrar, M. A., Viviano, B. L., Schreiber, R. D. (1994) Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). EMBO J. 13, 1591-1600.
-
(1994)
EMBO J.
, vol.13
, pp. 1591-1600
-
-
Greenlund, A.C.1
Farrar, M.A.2
Viviano, B.L.3
Schreiber, R.D.4
-
42
-
-
0026002416
-
Identification of two regions within the cytoplasmic domain of the human interferon-gamma receptor required for function
-
Farrar, M. A., Fernandez-Luna, J., Schreiber, R. D. (1991) Identification of two regions within the cytoplasmic domain of the human interferon-gamma receptor required for function. J. Biol. Chem. 266, 19626-19635.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19626-19635
-
-
Farrar, M.A.1
Fernandez-Luna, J.2
Schreiber, R.D.3
-
43
-
-
0027048766
-
Identification of a functionally important sequence in the C terminus of the interferon-gamma receptor
-
Farrar, M. A., Campbell, J. D., Schreiber, R. D. (1992) Identification of a functionally important sequence in the C terminus of the interferon-gamma receptor. Proc. Natl. Acad. Sci. USA 89, 11706-11710.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11706-11710
-
-
Farrar, M.A.1
Campbell, J.D.2
Schreiber, R.D.3
-
44
-
-
0026462899
-
Structural analysis of the human interferon gamma receptor: A small segment of the intracellular domain is specifically required for class I major histocompatibility complex antigen induction and antiviral activity
-
Cook, J. R., Jung, V., Schwartz, B., Wang, P., Pestka, S. (1992) Structural analysis of the human interferon gamma receptor: a small segment of the intracellular domain is specifically required for class I major histocompatibility complex antigen induction and antiviral activity. Proc. Natl. Acad. Sci. USA 89, 11317-11321.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11317-11321
-
-
Cook, J.R.1
Jung, V.2
Schwartz, B.3
Wang, P.4
Pestka, S.5
-
45
-
-
0027411525
-
The molecular cell biology of interferon-gamma and its receptor
-
Farrar, M. A., Schreiber, R. D. (1993) The molecular cell biology of interferon-gamma and its receptor. Annu. Rev. Immunol. 11, 571-611.
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 571-611
-
-
Farrar, M.A.1
Schreiber, R.D.2
-
46
-
-
0029130819
-
Interaction between the components of the interferon gamma receptor complex
-
Kotenko, S. V., Izotova, L. S., Pollack, B. P., Mariano, T. M., Donnelly, R. J., Muthukumaran, G., Cook, J. R., Garotta, C., Silvennoinen, O., Ihle, J. N., et al. (1995) Interaction between the components of the interferon gamma receptor complex. J. Biol. Chem. 270, 20915-20921.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20915-20921
-
-
Kotenko, S.V.1
Izotova, L.S.2
Pollack, B.P.3
Mariano, T.M.4
Donnelly, R.J.5
Muthukumaran, G.6
Cook, J.R.7
Garotta, C.8
Silvennoinen, O.9
Ihle, J.N.10
-
47
-
-
9344257897
-
Ligand-induced assembly and activation of the gamma interferon receptor in intact cells
-
Bach, E. A., Tanner, J. W., Marsters, S., Ashkenazi, A., Aguet, M., Shaw, A. S., Schreiber, R. D. (1996) Ligand-induced assembly and activation of the gamma interferon receptor in intact cells. Mol. Cell. Biol. 16, 3214-3221.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3214-3221
-
-
Bach, E.A.1
Tanner, J.W.2
Marsters, S.3
Ashkenazi, A.4
Aguet, M.5
Shaw, A.S.6
Schreiber, R.D.7
-
48
-
-
0031424937
-
The interferon gamma (IFN-gamma) receptor: A paradigm for the multichain cytokine receptor
-
Pestka, S., Kotenko, S. V., Muthukumaran, G., Izotova, L. S., Cook, J. R., Garotta, G. (1997) The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine Growth Factor Rev. 8, 189-206.
-
(1997)
Cytokine Growth Factor Rev.
, vol.8
, pp. 189-206
-
-
Pestka, S.1
Kotenko, S.V.2
Muthukumaran, G.3
Izotova, L.S.4
Cook, J.R.5
Garotta, G.6
-
49
-
-
0030481093
-
The intracellular domain of the second chain of the interferon-gamma receptor is interchangeable between species
-
Muthukumaran, G., Donnelly, R. J., Ebensperger, C., Mariano, T. M., Garotta, G., Dembic, Z., Poast, J., Baron, S., Pestka, S. (1996) The intracellular domain of the second chain of the interferon-gamma receptor is interchangeable between species. J. Interferon Cytokine Res. 16, 1039-1045.
-
(1996)
J. Interferon Cytokine Res.
, vol.16
, pp. 1039-1045
-
-
Muthukumaran, G.1
Donnelly, R.J.2
Ebensperger, C.3
Mariano, T.M.4
Garotta, G.5
Dembic, Z.6
Poast, J.7
Baron, S.8
Pestka, S.9
-
50
-
-
0026086546
-
The extracellular domain of the human interferon gamma receptor interacts with a species-specific signal transducer
-
Gibbs, V. C., Williams, S. R., Gray, P. W., Schreiber, R. D., Pennica, D., Rice, C., Goeddel, D. V. (1991) The extracellular domain of the human interferon gamma receptor interacts with a species-specific signal transducer. Mol. Cell. Biol. 11, 5860-5866.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 5860-5866
-
-
Gibbs, V.C.1
Williams, S.R.2
Gray, P.W.3
Schreiber, R.D.4
Pennica, D.5
Rice, C.6
Goeddel, D.V.7
-
51
-
-
0026707668
-
Chimeric interferon-gamma receptors demonstrate that an accessory factor required for activity interacts with the extracellular domain
-
Hibino, Y., Kumar, C. S., Mariano, T. M., Lai, D. H., Pestka, S. (1992) Chimeric interferon-gamma receptors demonstrate that an accessory factor required for activity interacts with the extracellular domain. J. Biol. Chem. 267, 3741-3749.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3741-3749
-
-
Hibino, Y.1
Kumar, C.S.2
Mariano, T.M.3
Lai, D.H.4
Pestka, S.5
-
52
-
-
0026510367
-
Functional characterization of a hybrid human-mouse interferon gamma receptor: Evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer
-
Hemmi, S., Merlin, G., Aguet, M. (1992) Functional characterization of a hybrid human-mouse interferon gamma receptor: evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer. Proc. Natl. Acad. Sci. USA 89, 2737-2741.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2737-2741
-
-
Hemmi, S.1
Merlin, G.2
Aguet, M.3
-
53
-
-
0027462395
-
The human gamma interferon receptor accessory factor encoded by chromosome 21 transduces the signal for the induction of 2′,5′ -oligoadenylate-synthetase, resistance to virus cytopathic effect, and major histocompatibility complex class I antigens
-
Kalina, U., Ozmen, L., Di Padova, K., Gentz, R., Garotta, G. (1993) The human gamma interferon receptor accessory factor encoded by chromosome 21 transduces the signal for the induction of 2′,5′ -oligoadenylate-synthetase, resistance to virus cytopathic effect, and major histocompatibility complex class I antigens. J. Virol. 67, 1702-1706.
-
(1993)
J. Virol.
, vol.67
, pp. 1702-1706
-
-
Kalina, U.1
Ozmen, L.2
Di Padova, K.3
Gentz, R.4
Garotta, G.5
-
54
-
-
0027464928
-
Immune response in mice that lack the interferon-gamma receptor
-
Huang, S., Hendriks, W., Althage, A., Hemmi, S., Bluethmaun, H., Kamijo, R., Vilcek, J., Zinkernagel, R. M., Aguet, M. (1993) Immune response in mice that lack the interferon-gamma receptor. Science 259, 1742-1745.
-
(1993)
Science
, vol.259
, pp. 1742-1745
-
-
Huang, S.1
Hendriks, W.2
Althage, A.3
Hemmi, S.4
Bluethmaun, H.5
Kamijo, R.6
Vilcek, J.7
Zinkernagel, R.M.8
Aguet, M.9
-
55
-
-
0035838272
-
Inflammation and lymphocyte activation during mycobacterial infection in the interferon-gamma-deficient mouse
-
Pearl, J. E., Saunders, B., Ehlers, S., Orme, I. M., Cooper, A. M. (2001) Inflammation and lymphocyte activation during mycobacterial infection in the interferon-gamma-deficient mouse. Cell. Immunol. 211, 43-50.
-
(2001)
Cell. Immunol.
, vol.211
, pp. 43-50
-
-
Pearl, J.E.1
Saunders, B.2
Ehlers, S.3
Orme, I.M.4
Cooper, A.M.5
-
56
-
-
0029414784
-
Immune defence in mice lacking type I and/or type II interferon receptors
-
van den Broek, M. F., Muller, U., Huang, S., Zinkernagel, R. M., Aguet, M. (1995) Immune defence in mice lacking type I and/or type II interferon receptors. Immunol. Rev. 148, 5-18.
-
(1995)
Immunol. Rev.
, vol.148
, pp. 5-18
-
-
Van Den Broek, M.F.1
Muller, U.2
Huang, S.3
Zinkernagel, R.M.4
Aguet, M.5
-
57
-
-
0010228473
-
Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection
-
Buchmeier, N. A., Schreiber, R. D. (1985) Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection. Proc. Natl. Acad. Sci. USA 82, 7404-7408.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 7404-7408
-
-
Buchmeier, N.A.1
Schreiber, R.D.2
-
58
-
-
0027260588
-
Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide
-
Kamijo, R., Le, J., Shapiro, D., Havell, E. A., Huang, S., Aguet, M., Bosland, M., Vilcek, J. (1993) Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide. J. Exp. Med. 178, 1435-1440.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1435-1440
-
-
Kamijo, R.1
Le, J.2
Shapiro, D.3
Havell, E.A.4
Huang, S.5
Aguet, M.6
Bosland, M.7
Vilcek, J.8
-
59
-
-
0023895411
-
Interferon-gamma: The major mediator of resistance against Toxoplasma gondii
-
Suzuki, Y., Orellana, M. A., Schreiber, R. D., Remington, J. S. (1988) Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science 240, 516-518.
-
(1988)
Science
, vol.240
, pp. 516-518
-
-
Suzuki, Y.1
Orellana, M.A.2
Schreiber, R.D.3
Remington, J.S.4
-
60
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
Muller, U., Steinhoff, U., Reis, L. F., Hemmi, S., Pavlovic, J., Zinkernagel, R. M., Aguet, M. (1994) Functional role of type I and type II interferons in antiviral defense. Science 264, 1918-1921.
-
(1994)
Science
, vol.264
, pp. 1918-1921
-
-
Muller, U.1
Steinhoff, U.2
Reis, L.F.3
Hemmi, S.4
Pavlovic, J.5
Zinkernagel, R.M.6
Aguet, M.7
-
61
-
-
0029678749
-
Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies
-
Kimura, T., Kadokawa, Y., Harada, H., Matsumoto, M., Sato, M., Kashiwazaki, Y., Tarutani, M., Tan, R. S., Takasugi, T., Matsuyama, T., Mak, T. W., Noguchi, S., Taniguchi, T. (1996) Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies. Genes Cells 1, 115-124.
-
(1996)
Genes Cells
, vol.1
, pp. 115-124
-
-
Kimura, T.1
Kadokawa, Y.2
Harada, H.3
Matsumoto, M.4
Sato, M.5
Kashiwazaki, Y.6
Tarutani, M.7
Tan, R.S.8
Takasugi, T.9
Matsuyama, T.10
Mak, T.W.11
Noguchi, S.12
Taniguchi, T.13
-
62
-
-
0034954034
-
Interferons alpha and beta as immune regulators-a new look
-
Biron, C. A. (2001) Interferons alpha and beta as immune regulators-a new look. Immunity 14, 661-664.
-
(2001)
Immunity
, vol.14
, pp. 661-664
-
-
Biron, C.A.1
-
63
-
-
0033967256
-
Partial interferon-gamma receptor signaling chain deficiency in a patient with bacille Calmette-Guerin and Mycobacterium abscessus infection
-
Doffinger, R., Jouanguy, E., Dupuis, S., Fondaneche, M. C., Stephan, J. L., Emile, J. F., Lamhamedi-Cherradi, S., Altare, F., Pallier, A., Barcenas-Morales, G., Meinl, E., Krause, C., Pestka, S., Schreiber, R. D., Novelli, F., Casanova, J. L. (2000) Partial interferon-gamma receptor signaling chain deficiency in a patient with bacille Calmette-Guerin and Mycobacterium abscessus infection. J. Infect. Dis. 181, 379-384.
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 379-384
-
-
Doffinger, R.1
Jouanguy, E.2
Dupuis, S.3
Fondaneche, M.C.4
Stephan, J.L.5
Emile, J.F.6
Lamhamedi-Cherradi, S.7
Altare, F.8
Pallier, A.9
Barcenas-Morales, G.10
Meinl, E.11
Krause, C.12
Pestka, S.13
Schreiber, R.D.14
Novelli, F.15
Casanova, J.L.16
-
64
-
-
0032948177
-
A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection
-
Jouanguy, E., Lamhamedi-Cherradi, S., Lammas, D., Dorman, S. E., Fondaneche, M. C., Dupuis, S., Doffinger, R., Altare, F., Girdlestone, J., Emile, J. F., Ducoulombier, H., Edgar, D., Clarke, J., Oxelius, V. A., Brai, M., Novelli, V., Heyne, K., Fischer, A., Holland, S. M., Kumararatne, D. S., Schreiber, R. D., Casanova, J. L. (1999) A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat. Genet. 21, 370-378.
-
(1999)
Nat. Genet.
, vol.21
, pp. 370-378
-
-
Jouanguy, E.1
Lamhamedi-Cherradi, S.2
Lammas, D.3
Dorman, S.E.4
Fondaneche, M.C.5
Dupuis, S.6
Doffinger, R.7
Altare, F.8
Girdlestone, J.9
Emile, J.F.10
Ducoulombier, H.11
Edgar, D.12
Clarke, J.13
Oxelius, V.A.14
Brai, M.15
Novelli, V.16
Heyne, K.17
Fischer, A.18
Holland, S.M.19
Kumararatne, D.S.20
Schreiber, R.D.21
Casanova, J.L.22
more..
-
65
-
-
0031468410
-
Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis
-
Jouanguy, E., Lamhamedi-Cherradi, S., Altare, F., Fondaneche, M. C., Tuerlinckx, D., Blanche, S., Emile, J. F., Gaillard, J. L., Schreiber, R., Levin, M., Fischer, A., Hivroz, C., Casanova, J. L. (1997) Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis. J. Clin. Invest. 100, 2658-2664.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2658-2664
-
-
Jouanguy, E.1
Lamhamedi-Cherradi, S.2
Altare, F.3
Fondaneche, M.C.4
Tuerlinckx, D.5
Blanche, S.6
Emile, J.F.7
Gaillard, J.L.8
Schreiber, R.9
Levin, M.10
Fischer, A.11
Hivroz, C.12
Casanova, J.L.13
-
66
-
-
0030881918
-
Infectious in IFNGR-1-deficient children
-
Jouanguy, E., Altare, F., Lamhamedi-Cherradi, S., Casanova, J. L. (1997) Infectious in IFNGR-1-deficient children. J. Interferon Cytokine Res. 17, 583-587.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 583-587
-
-
Jouanguy, E.1
Altare, F.2
Lamhamedi-Cherradi, S.3
Casanova, J.L.4
-
67
-
-
0030467174
-
A mutation in the interferon-gamma-receptor gene susceptibility to mycobacterial infection
-
Newport, M. J., Huxley, C. M., Huston, S., Hawrylowicz, C. M., Oostra, B. A., Williamson, R., Levin, M. (1996) A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. N. Engl. J. Med. 335, 1941-1949.
-
(1996)
N. Engl. J. Med
, vol.335
, pp. 1941-1949
-
-
Newport, M.J.1
Huxley, C.M.2
Huston, S.3
Hawrylowicz, C.M.4
Oostra, B.A.5
Williamson, R.6
Levin, M.7
-
68
-
-
0030934873
-
Fatal disseminated Mycobacterium smegmatis infection in a child with inherited interferon gamma receptor deficiency
-
Pierre-Audigier, C., Jouanguy, E., Lamhamedi, S., Altare, F., Rauzier, J., Vincent, V., Canioni, D., Emile, J. F., Fischer, A., Blanche, S., Gaillard, J. L., Casanova, J. L. (1997) Fatal disseminated Mycobacterium smegmatis infection in a child with inherited interferon gamma receptor deficiency. Clin. Infect. Dis. 24, 982-984.
-
(1997)
Clin. Infect. Dis.
, vol.24
, pp. 982-984
-
-
Pierre-Audigier, C.1
Jouanguy, E.2
Lamhamedi, S.3
Altare, F.4
Rauzier, J.5
Vincent, V.6
Canioni, D.7
Emile, J.F.8
Fischer, A.9
Blanche, S.10
Gaillard, J.L.11
Casanova, J.L.12
-
69
-
-
0032819175
-
Listeria monocytogenes and recurrent mycobacterial infections in a child with complete interferon-gamma-receptor (IFNgammaR1) deficiency: Mutational analysis and evaluation of therapeutic options
-
Roesler, J., Kofink, B., Wendisch, J., Heyden, S., Paul, D., Friedrich, W., Casanova, J. L., Leupold, W., Gahr, M., Rosen-Wolff, A. (1999) Listeria monocytogenes and recurrent mycobacterial infections in a child with complete interferon-gamma-receptor (IFNgammaR1) deficiency: mutational analysis and evaluation of therapeutic options. Exp. Hematol. 27, 1368-1374.
-
(1999)
Exp. Hematol.
, vol.27
, pp. 1368-1374
-
-
Roesler, J.1
Kofink, B.2
Wendisch, J.3
Heyden, S.4
Paul, D.5
Friedrich, W.6
Casanova, J.L.7
Leupold, W.8
Gahr, M.9
Rosen-Wolff, A.10
-
70
-
-
0030455878
-
Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection
-
Jouanguy, E., Altare, F., Lamhamedi, S., Revy, P., Emile, J. F., Newport, M., Levin, M., Blanche, S., Seboun, E., Fischer, A., Casanova, J. L. (1996) Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N. Engl. J. Med. 335, 1956-1961.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1956-1961
-
-
Jouanguy, E.1
Altare, F.2
Lamhamedi, S.3
Revy, P.4
Emile, J.F.5
Newport, M.6
Levin, M.7
Blanche, S.8
Seboun, E.9
Fischer, A.10
Casanova, J.L.11
-
71
-
-
0032103249
-
Mutation in the signal-transducing chain of the interferon-gamma receptor and susceptibility to mycobacterial infection
-
Dorman, S. E., Holland, S. M. (1998) Mutation in the signal-transducing chain of the interferon-gamma receptor and susceptibility to mycobacterial infection. J. Clin. Invest. 101, 2364-2369.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2364-2369
-
-
Dorman, S.E.1
Holland, S.M.2
-
72
-
-
0033497350
-
Viral infections in interferon-gamma receptor deficiency
-
Dorman, S. E., Uzel, G., Roesler, J., Bradley, J. S., Bastian, J., Billman, G., King, S., Filie, A., Schermerhorn, J., Holland, S. M. (1999) Viral infections in interferon-gamma receptor deficiency. J. Pediatr. 135, 640-643.
-
(1999)
J. Pediatr.
, vol.135
, pp. 640-643
-
-
Dorman, S.E.1
Uzel, G.2
Roesler, J.3
Bradley, J.S.4
Bastian, J.5
Billman, G.6
King, S.7
Filie, A.8
Schermerhorn, J.9
Holland, S.M.10
-
73
-
-
0019922739
-
Defective immune interferon production and natural killer activity associated with poor neutrophil mobility and delayed umbilical cord separation
-
Davies, E. G., Isaacs, D., Levinsky, R. J. (1982) Defective immune interferon production and natural killer activity associated with poor neutrophil mobility and delayed umbilical cord separation. Clin. Exp. Immunol. 50, 454-460.
-
(1982)
Clin. Exp. Immunol.
, vol.50
, pp. 454-460
-
-
Davies, E.G.1
Isaacs, D.2
Levinsky, R.J.3
-
74
-
-
0037011996
-
Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of interferon-gamma gene in a group of Italian centenarians
-
Lio, D., Scola, L., Crivello, A., Bonafe, M., Franceschi, C., Olivieri, F., Colonna-Romano, G., Candore, G., Caruso, C. (2002) Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of interferon-gamma gene in a group of Italian centenarians. Exp. Gerontol. 37, 315-319.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 315-319
-
-
Lio, D.1
Scola, L.2
Crivello, A.3
Bonafe, M.4
Franceschi, C.5
Olivieri, F.6
Colonna-Romano, G.7
Candore, G.8
Caruso, C.9
-
75
-
-
0035695728
-
Treatment with anti-interferon-gamma monoclonal antibodies modifies experimental autoimmune encephalomyelitis in interferon-gamma receptor knockout mice
-
Espejo, C., Penkowa, M., Saez-Torres, I., Xaus, J., Celada, A., Montalban, X., Martinez-Caceres, E. M. (2001) Treatment with anti-interferon-gamma monoclonal antibodies modifies experimental autoimmune encephalomyelitis in interferon-gamma receptor knockout mice. Exp. Neurol. 172, 460-468.
-
(2001)
Exp. Neurol.
, vol.172
, pp. 460-468
-
-
Espejo, C.1
Penkowa, M.2
Saez-Torres, I.3
Xaus, J.4
Celada, A.5
Montalban, X.6
Martinez-Caceres, E.M.7
-
76
-
-
0023879766
-
Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma
-
Billiau, A., Heremans, H., Vandekerckhove, F., Dijkmans, R., Sobis, H., Meulepas, E., Carton, H. (1988) Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma. J. Immunol. 140, 1506-1510.
-
(1988)
J. Immunol.
, vol.140
, pp. 1506-1510
-
-
Billiau, A.1
Heremans, H.2
Vandekerckhove, F.3
Dijkmans, R.4
Sobis, H.5
Meulepas, E.6
Carton, H.7
-
77
-
-
0018086341
-
Interferon treatment of NZB mice: Accelerated progression of autoimmune disease
-
Heremans, H., Billiau, A., Colombatti, A., Hilgers, J., de Somer, P. (1978) Interferon treatment of NZB mice: accelerated progression of autoimmune disease. Infect. Immun. 21, 925-930.
-
(1978)
Infect. Immun.
, vol.21
, pp. 925-930
-
-
Heremans, H.1
Billiau, A.2
Colombatti, A.3
Hilgers, J.4
De Somer, P.5
-
78
-
-
0023874728
-
Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis
-
Jacob, C. O., McDevitt, H. O. (1988) Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature 331, 356-358.
-
(1988)
Nature
, vol.331
, pp. 356-358
-
-
Jacob, C.O.1
McDevitt, H.O.2
-
79
-
-
0035433505
-
Interferon-gamma polymorphisms in systemic lupus erythematosus
-
Lee, J. Y., Goldman, D., Piliero, L. M., Petri, M., Sullivan, K. E. (2001) Interferon-gamma polymorphisms in systemic lupus erythematosus. Genes Immun. 2, 254-257.
-
(2001)
Genes Immun.
, vol.2
, pp. 254-257
-
-
Lee, J.Y.1
Goldman, D.2
Piliero, L.M.3
Petri, M.4
Sullivan, K.E.5
-
80
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
Baechler, E. C., Batliwalla, F. M., Karypis, C., Gaffney, P. M., Ortmann, W. A., Espe, K. J., Shark, K. B., Grande, W. J., Hughes, K. M., Kapur, V., Gregersen, P. K., Behrens, T. W. (2003) Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc. Natl. Acad. Sci. USA 100, 2610-2615.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2610-2615
-
-
Baechler, E.C.1
Batliwalla, F.M.2
Karypis, C.3
Gaffney, P.M.4
Ortmann, W.A.5
Espe, K.J.6
Shark, K.B.7
Grande, W.J.8
Hughes, K.M.9
Kapur, V.10
Gregersen, P.K.11
Behrens, T.W.12
-
81
-
-
0023126661
-
Exacerbations of multiple sclerosis in patients treated with gamma interferon
-
Panitch, H. S., Hirsch, R. L., Haley, A. S., Johnson, K. P. (1987) Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1, 893-895.
-
(1987)
Lancet
, vol.1
, pp. 893-895
-
-
Panitch, H.S.1
Hirsch, R.L.2
Haley, A.S.3
Johnson, K.P.4
-
82
-
-
0023841728
-
Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma
-
Sarvetnick, N., Liggitt, D., Pitts, S. L., Hansen, S. E., Stewart, T. A. (1988) Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 52, 773-782.
-
(1988)
Cell
, vol.52
, pp. 773-782
-
-
Sarvetnick, N.1
Liggitt, D.2
Pitts, S.L.3
Hansen, S.E.4
Stewart, T.A.5
-
83
-
-
0027986597
-
Association of polymorphism in the interferon gamma gene with IDDM
-
Awata, T., Matsumoto, C., Urakami, T., Hagura, R., Amemiya, S., Kanazawa, Y. (1994) Association of polymorphism in the interferon gamma gene with IDDM. Diabetologia 37, 1159-1162.
-
(1994)
Diabetologia
, vol.37
, pp. 1159-1162
-
-
Awata, T.1
Matsumoto, C.2
Urakami, T.3
Hagura, R.4
Amemiya, S.5
Kanazawa, Y.6
-
84
-
-
0031456802
-
Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes
-
Wang, B., Andre, I., Gonzalez, A., Katz, J. D., Aguet, M., Benoist, C., Mathis, D. (1997) Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes. Proc. Natl. Acad. Sci. USA 94, 13844-13849.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13844-13849
-
-
Wang, B.1
Andre, I.2
Gonzalez, A.3
Katz, J.D.4
Aguet, M.5
Benoist, C.6
Mathis, D.7
-
85
-
-
0032560475
-
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
-
Kaplan, D. H., Shankaran, V., Dighe, A. S., Stockert, E., Aguet, M., Old, L. J., Schreiber, R. D. (1998) Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc. Natl. Acad. Sci. USA 95, 7556-7561.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
Stockert, E.4
Aguet, M.5
Old, L.J.6
Schreiber, R.D.7
-
86
-
-
0028500836
-
Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors
-
Dighe, A. S., Richards, E., Old, L. J., Schreiber, R. D. (1994) Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors. Immunity 1, 447-456.
-
(1994)
Immunity
, vol.1
, pp. 447-456
-
-
Dighe, A.S.1
Richards, E.2
Old, L.J.3
Schreiber, R.D.4
-
87
-
-
0033909434
-
Immune-inflammatory mechanisms in IFNgamma-mediated anti-tumor activity
-
Tannenbaum, C. S., Hamilton, T. A. (2000) Immune-inflammatory mechanisms in IFNgamma-mediated anti-tumor activity. Semin. Cancer Biol. 10, 113-123.
-
(2000)
Semin. Cancer Biol.
, vol.10
, pp. 113-123
-
-
Tannenbaum, C.S.1
Hamilton, T.A.2
-
88
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J., Schreiber, R. D. (2002) Cancer immunoediting: from immunosurveillance to tumor escape. Nat. Immunol. 3, 991-998.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
Old, L.J.4
Schreiber, R.D.5
-
89
-
-
0036005884
-
The roles of IFN gamma in protection against tumor development and cancer immunoediting
-
Ikeda, H., Old, L. J., Schreiber, R. D. (2002) The roles of IFN gamma in protection against tumor development and cancer immunoediting. Cytokine Growth Factor Rev. 13, 95-109.
-
(2002)
Cytokine Growth Factor Rev.
, vol.13
, pp. 95-109
-
-
Ikeda, H.1
Old, L.J.2
Schreiber, R.D.3
-
90
-
-
0035928897
-
So many ligands, so few transcription factors: A new paradigm for signaling through the STAT transcription factors
-
Subramaniam, P. S., Torres, B. A., Johnson, H. M. (2001) So many ligands, so few transcription factors: a new paradigm for signaling through the STAT transcription factors. Cytokine 15, 175-187.
-
(2001)
Cytokine
, vol.15
, pp. 175-187
-
-
Subramaniam, P.S.1
Torres, B.A.2
Johnson, H.M.3
-
91
-
-
0029149376
-
The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors
-
Sakatsume, M., Igarashi, K., Winestock, K. D., Garotta, G., Larner, A. C., Finbloom, D. S. (1995) The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors. J. Biol. Chem. 270, 17528-17534.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17528-17534
-
-
Sakatsume, M.1
Igarashi, K.2
Winestock, K.D.3
Garotta, G.4
Larner, A.C.5
Finbloom, D.S.6
-
92
-
-
0029068150
-
Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain
-
Marsters, S. A., Pennica, D., Bach, E., Schreiber, R. D., Ashkenazi, A. (1995) Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain. Proc. Natl. Acad. Sci. USA 92, 5401-5405.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5401-5405
-
-
Marsters, S.A.1
Pennica, D.2
Bach, E.3
Schreiber, R.D.4
Ashkenazi, A.5
-
93
-
-
0012263559
-
Seeing the light: Preassembly and ligand-induced changes of the interferon gamma receptor complex in cells
-
Krause, C. D., Mei, E., Xie, J., Jia, Y., Bopp, M. A., Hochstrasser, R. M., Pestka, S. (2002) Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells. Mol. Cell. Proteomics 1, 805-815.
-
(2002)
Mol. Cell. Proteomics
, vol.1
, pp. 805-815
-
-
Krause, C.D.1
Mei, E.2
Xie, J.3
Jia, Y.4
Bopp, M.A.5
Hochstrasser, R.M.6
Pestka, S.7
-
94
-
-
0025730621
-
Three-dimensional structure of recombinant human interferon-gamma
-
Ealick, S. E., Cook, W. J., Vijay-Kumar, S., Carson, M., Nagabhushan, T. L., Trotta, P. P., Bugg, C. E. (1991) Three-dimensional structure of recombinant human interferon-gamma. Science 252, 698-702.
-
(1991)
Science
, vol.252
, pp. 698-702
-
-
Ealick, S.E.1
Cook, W.J.2
Vijay-Kumar, S.3
Carson, M.4
Nagabhushan, T.L.5
Trotta, P.P.6
Bugg, C.E.7
-
95
-
-
0029067876
-
Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor
-
Walter, M. R., Windsor, W. T., Nagabhushan, T. L., Lundell, D. J., Lunn, C. A., Zauodny, P. J., Narula, S. K. (1995) Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor. Nature 376, 230-235.
-
(1995)
Nature
, vol.376
, pp. 230-235
-
-
Walter, M.R.1
Windsor, W.T.2
Nagabhushan, T.L.3
Lundell, D.J.4
Lunn, C.A.5
Zauodny, P.J.6
Narula, S.K.7
-
96
-
-
0026759532
-
Stoichiometry of interaction between interferon gamma and its receptor
-
Fountoulakis, M., Zulauf, M., Lustig, A., Garotta, G. (1992) Stoichiometry of interaction between interferon gamma and its receptor. Eur. J. Biochem. 208, 781-787.
-
(1992)
Eur. J. Biochem.
, vol.208
, pp. 781-787
-
-
Fountoulakis, M.1
Zulauf, M.2
Lustig, A.3
Garotta, G.4
-
97
-
-
0027249338
-
Interferon-gamma induces receptor dimerization in solution and on cells
-
Greenlund, A. C., Schreiber, R. D., Goeddel, D. V., Pennica, D. (1993) Interferon-gamma induces receptor dimerization in solution and on cells. J. Biol. Chem. 268, 18103-18110.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18103-18110
-
-
Greenlund, A.C.1
Schreiber, R.D.2
Goeddel, D.V.3
Pennica, D.4
-
98
-
-
0030062769
-
Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state
-
Briscoe, J., Rogers, N. C., Witthuhn, B. A., Watling, D., Harpur, A. G., Wilks, A. F., Stark, G. R., Ihle, J. N., Kerr, I. M. (1996) Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state. EMBO J. 15, 799-809.
-
(1996)
EMBO J.
, vol.15
, pp. 799-809
-
-
Briscoe, J.1
Rogers, N.C.2
Witthuhn, B.A.3
Watling, D.4
Harpur, A.G.5
Wilks, A.F.6
Stark, G.R.7
Ihle, J.N.8
Kerr, I.M.9
-
99
-
-
0028175969
-
Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor
-
Igarashi, K., Garotta, G., Ozmen, L., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Larner, A. C., Finbloom, D. S. (1994) Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. J. Biol. Chem. 269, 14333-14336.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14333-14336
-
-
Igarashi, K.1
Garotta, G.2
Ozmen, L.3
Ziemiecki, A.4
Wilks, A.F.5
Harpur, A.G.6
Larner, A.C.7
Finbloom, D.S.8
-
100
-
-
0028979707
-
Stat recruitment by tyrosine-phosphorylated cytokine receptors: An ordered reversible affinity-driven process
-
Greenlund, A. C., Morales, M. O., Viviano, B. L., Yan, H., Krolewski, J., Schreiber, R. D. (1995) Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. Immunity 2, 677-687.
-
(1995)
Immunity
, vol.2
, pp. 677-687
-
-
Greenlund, A.C.1
Morales, M.O.2
Viviano, B.L.3
Yan, H.4
Krolewski, J.5
Schreiber, R.D.6
-
101
-
-
0028946158
-
Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway
-
Heim, M. H., Kerr, I. M., Stark, G. R., Darnell Jr., J. E. (1995) Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway. Science 267, 1347-1349.
-
(1995)
Science
, vol.267
, pp. 1347-1349
-
-
Heim, M.H.1
Kerr, I.M.2
Stark, G.R.3
Darnell Jr., J.E.4
-
102
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell Jr., J. E., Kerr, I. M., Stark, G. R. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
103
-
-
0029069145
-
Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
-
Schindler, C., Darnell Jr., J. E. (1995) Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 64, 621-651.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell Jr., J.E.2
-
104
-
-
0034658696
-
Complex roles of Stat1 in regulating gene expression
-
Ramana, C. V., Chatterjee-Kishore, M., Nguyen, H., Stark, G. R. (2000) Complex roles of Stat1 in regulating gene expression. Oncogene 19, 2619-2627.
-
(2000)
Oncogene
, vol.19
, pp. 2619-2627
-
-
Ramana, C.V.1
Chatterjee-Kishore, M.2
Nguyen, H.3
Stark, G.R.4
-
105
-
-
0030936627
-
GAS elements: A few nucleotides with a major impact on cytokine-induced gene expression
-
Decker, T., Kovarik, P., Meinke, A. (1997) GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression. J. Interferon Cytokine Res. 17, 121-134.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 121-134
-
-
Decker, T.1
Kovarik, P.2
Meinke, A.3
-
106
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M. A., White, J. W., Sheehan, K. C., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., Carver-Moore, K., DuBois, R. N., Clark, R., Aguet, M., Schreiber, R. D. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84, 431-442.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
White, J.W.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
Carver-Moore, K.11
DuBois, R.N.12
Clark, R.13
Aguet, M.14
Schreiber, R.D.15
-
107
-
-
0025733262
-
The control of interferon-inducible gene expression
-
Kerr, I. M., Stark, G. R. (1991) The control of interferon-inducible gene expression. FEBS Lett. 285, 194-198.
-
(1991)
FEBS Lett.
, vol.285
, pp. 194-198
-
-
Kerr, I.M.1
Stark, G.R.2
-
108
-
-
0031731993
-
Interleukin-4 and interferon-gamma: The quintessence of a mutual antagonistic relationship
-
Paludan, S. R. (1998) Interleukin-4 and interferon-gamma: the quintessence of a mutual antagonistic relationship. Scand. J. Immunol. 48, 459-468.
-
(1998)
Scand. J. Immunol.
, vol.48
, pp. 459-468
-
-
Paludan, S.R.1
-
109
-
-
0032577678
-
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
-
Chen, X., Vinkemeier, U., Zhao, Y., Jeruzalmi, D., Darnell Jr., J. E., Kuriyan, J. (1998) Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 93, 827-839.
-
(1998)
Cell
, vol.93
, pp. 827-839
-
-
Chen, X.1
Vinkemeier, U.2
Zhao, Y.3
Jeruzalmi, D.4
Darnell Jr., J.E.5
Kuriyan, J.6
-
110
-
-
0033598839
-
Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway
-
Kovarik, P., Stoiber, D., Eyers, P. A., Menghini, R., Neininger, A., Gaestel, M., Cohen, P., Decker, T. (1999) Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway. Proc. Natl. Acad. Sci. USA 96, 13956-13961.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13956-13961
-
-
Kovarik, P.1
Stoiber, D.2
Eyers, P.A.3
Menghini, R.4
Neininger, A.5
Gaestel, M.6
Cohen, P.7
Decker, T.8
-
111
-
-
0033569905
-
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
-
Goh, K. C., Haque, S. J., Williams, B. R. (1999) p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. EMBO J. 18, 5601-5608.
-
(1999)
EMBO J.
, vol.18
, pp. 5601-5608
-
-
Goh, K.C.1
Haque, S.J.2
Williams, B.R.3
-
112
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen, Z., Zhong, Z., Darnell Jr., J. E. (1995) Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82, 241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
-
113
-
-
0028942656
-
Requirement of serine phosphorylation for formation of STAT-promoter complexes
-
Zhang, X., Blenis, J., Li, H. C., Schindler, C., Chen-Kiang, S. (1995) Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 267, 1990-1994.
-
(1995)
Science
, vol.267
, pp. 1990-1994
-
-
Zhang, X.1
Blenis, J.2
Li, H.C.3
Schindler, C.4
Chen-Kiang, S.5
-
114
-
-
0027493650
-
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
-
Shuai, K., Stark, G. R., Kerr, I. M., Darnell Jr., J. E. (1993) A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science 261, 1744-1746.
-
(1993)
Science
, vol.261
, pp. 1744-1746
-
-
Shuai, K.1
Stark, G.R.2
Kerr, I.M.3
Darnell Jr., J.E.4
-
115
-
-
0028349904
-
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
-
Shuai, K., Horvath, C. M., Huang, L. H., Qureshi, S. A., Cowburn, D., Darnell Jr., J. E. (1994) Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell 76, 821-828.
-
(1994)
Cell
, vol.76
, pp. 821-828
-
-
Shuai, K.1
Horvath, C.M.2
Huang, L.H.3
Qureshi, S.A.4
Cowburn, D.5
Darnell Jr., J.E.6
-
116
-
-
0033065879
-
Activation of the transcription factor ISGF3 by interferon-gamma
-
Matsumoto, M., Tanaka, N., Harada, H., Kimura, T., Yokochi, T., Kitagawa, M., Schindler, C., Taniguchi, T. (1999) Activation of the transcription factor ISGF3 by interferon-gamma. Biol. Chem. 380, 699-703.
-
(1999)
Biol. Chem.
, vol.380
, pp. 699-703
-
-
Matsumoto, M.1
Tanaka, N.2
Harada, H.3
Kimura, T.4
Yokochi, T.5
Kitagawa, M.6
Schindler, C.7
Taniguchi, T.8
-
117
-
-
0031657551
-
How cells respond to interferons
-
Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H., Schreiber, R. D. (1998) How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
118
-
-
0030183109
-
ISGF3 gamma p48, a specificity switch for interferon activated transcription factors
-
Bluyssen, A. R., Durbin, J. E., Levy, D. E. (1996) ISGF3 gamma p48, a specificity switch for interferon activated transcription factors. Cytokine Growth Factor Rev. 7, 11-17.
-
(1996)
Cytokine Growth Factor Rev.
, vol.7
, pp. 11-17
-
-
Bluyssen, A.R.1
Durbin, J.E.2
Levy, D.E.3
-
119
-
-
0034159937
-
Association of STATs with relatives and friends
-
Chatterjee-Kishore, M., van den Akker, F., Stark, G. R. (2000) Association of STATs with relatives and friends. Trends Cell Biol. 10, 106-111.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 106-111
-
-
Chatterjee-Kishore, M.1
Van Den Akker, F.2
Stark, G.R.3
-
120
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker, T., Kovarik, P. (2000) Serine phosphorylation of STATs. Oncogene 19, 2628-2637.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
121
-
-
0030875862
-
Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase
-
Zhu, X., Wen, Z., Xu, L. Z., Darnell Jr., J. E. (1997) Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase. Mol. Cell. Biol. 17, 6618-6623.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6618-6623
-
-
Zhu, X.1
Wen, Z.2
Xu, L.Z.3
Darnell Jr., J.E.4
-
122
-
-
0029655458
-
The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein
-
Horvath, C. M., Darnell Jr., J. E. (1996) The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein. J. Virol. 70, 647-650.
-
(1996)
J. Virol.
, vol.70
, pp. 647-650
-
-
Horvath, C.M.1
Darnell Jr., J.E.2
-
123
-
-
0032127465
-
Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation
-
Kovarik, P., Stoiber, D., Novy, M., Decker, T. (1998) Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation. EMBO J. 17, 3660-3668.
-
(1998)
EMBO J.
, vol.17
, pp. 3660-3668
-
-
Kovarik, P.1
Stoiber, D.2
Novy, M.3
Decker, T.4
-
124
-
-
0033561559
-
The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation
-
Gollob, J. A., Schnipper, C. P., Murphy, E. A., Ritz, J., Frank, D. A. (1999) The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation. J. Immunol. 162, 4472-4481.
-
(1999)
J. Immunol.
, vol.162
, pp. 4472-4481
-
-
Gollob, J.A.1
Schnipper, C.P.2
Murphy, E.A.3
Ritz, J.4
Frank, D.A.5
-
125
-
-
0030026354
-
Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells. Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and STAT1 alpha
-
Singh, K., Balligand, J. L., Fischer, T. A., Smith, T. W., Kelly, R. A. (1996) Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells. Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and STAT1 alpha. J. Biol. Chem. 271, 1111-1117.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1111-1117
-
-
Singh, K.1
Balligand, J.L.2
Fischer, T.A.3
Smith, T.W.4
Kelly, R.A.5
-
126
-
-
0035019373
-
IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell line
-
Chan, E. D., Riches, D. W. (2001) IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell line. Am. J. Physiol. Cell Physiol. 280, C441-C450.
-
(2001)
Am. J. Physiol. Cell Physiol.
, vol.280
-
-
Chan, E.D.1
Riches, D.W.2
-
127
-
-
0037040979
-
Activation of signal transducer and activator of transcription 1 (STAT1) is not sufficient for the induction of STAT1-dependent genes in endothelial cells. Comparison of interferon-gamma and oncostatin M
-
Mahboubi, K., Pober, J. S. (2002) Activation of signal transducer and activator of transcription 1 (STAT1) is not sufficient for the induction of STAT1-dependent genes in endothelial cells. Comparison of interferon-gamma and oncostatin M. J. Biol. Chem. 277, 8012-8021.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8012-8021
-
-
Mahboubi, K.1
Pober, J.S.2
-
128
-
-
0034624967
-
Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes
-
Ouchi, T., Lee, S. W., Ouchi, M., Aaronson, S. A., Horvath, C. M. (2000) Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes. Proc. Natl. Acad. Sci. USA 97, 5208-5213.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5208-5213
-
-
Ouchi, T.1
Lee, S.W.2
Ouchi, M.3
Aaronson, S.A.4
Horvath, C.M.5
-
129
-
-
0032401780
-
Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation
-
Zhang, J. J., Zhao, Y., Chait, B. T., Lathem, W. W., Ritzi, M., Knippers, R., Darnell Jr., J. E., (1998) Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation. EMBO J. 17, 6963-6971.
-
(1998)
EMBO J.
, vol.17
, pp. 6963-6971
-
-
Zhang, J.J.1
Zhao, Y.2
Chait, B.T.3
Lathem, W.W.4
Ritzi, M.5
Knippers, R.6
Darnell Jr., J.E.7
-
130
-
-
0029903770
-
DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: Interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites
-
Vinkemeier, U., Cohen, S. L., Moarefi, I., Chait, B. T., Kuriyan, J., Darnell Jr., J. E. (1996) DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J. 15, 5616-5626.
-
(1996)
EMBO J.
, vol.15
, pp. 5616-5626
-
-
Vinkemeier, U.1
Cohen, S.L.2
Moarefi, I.3
Chait, B.T.4
Kuriyan, J.5
Darnell Jr., J.E.6
-
131
-
-
0029739627
-
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
-
Xu, X., Sun, Y. L., Hoey, T. (1996) Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain. Science 273, 794-797.
-
(1996)
Science
, vol.273
, pp. 794-797
-
-
Xu, X.1
Sun, Y.L.2
Hoey, T.3
-
132
-
-
0030659512
-
Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
-
Kumar, A., Commane, M., Flickinger, T. W., Horvath, C. M., Stark, G. R. (1997) Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278, 1630-1632.
-
(1997)
Science
, vol.278
, pp. 1630-1632
-
-
Kumar, A.1
Commane, M.2
Flickinger, T.W.3
Horvath, C.M.4
Stark, G.R.5
-
133
-
-
0034142230
-
STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma
-
Lee, C. K., Smith, E., Gimeno, R., Gertner, R., Levy, D. E. (2000) STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma. J. Immunol. 164, 1286-1292.
-
(2000)
J. Immunol.
, vol.164
, pp. 1286-1292
-
-
Lee, C.K.1
Smith, E.2
Gimeno, R.3
Gertner, R.4
Levy, D.E.5
-
134
-
-
0034254726
-
How Stat1 mediates constitutive gene expression: A complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene
-
Chatterjee-Kishore, M., Wright, K. L., Ting, J. P., Stark, G. R. (2000) How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. EMBO J. 19, 4111-4122.
-
(2000)
EMBO J.
, vol.19
, pp. 4111-4122
-
-
Chatterjee-Kishore, M.1
Wright, K.L.2
Ting, J.P.3
Stark, G.R.4
-
135
-
-
0030670639
-
Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1
-
Sekimoto, T., Imamoto, N., Nakajima, K., Hirano, T., Yoneda, Y. (1997) Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J. 16, 7067-7077.
-
(1997)
EMBO J.
, vol.16
, pp. 7067-7077
-
-
Sekimoto, T.1
Imamoto, N.2
Nakajima, K.3
Hirano, T.4
Yoneda, Y.5
-
136
-
-
17144460324
-
STAT1 from the cell membrane to the DNA
-
Lillemeier, B. F., Kosler, M., Kerr, I. M. (2001) STAT1 from the cell membrane to the DNA. EMBO J. 20, 2508-2517.
-
(2001)
EMBO J.
, vol.20
, pp. 2508-2517
-
-
Lillemeier, B.F.1
Kosler, M.2
Kerr, I.M.3
-
137
-
-
0034669111
-
Nuclear export signal located within the DNA-binding domain of the STAT1 transcription factor
-
McBride, K. M., McDonald, C., Reich, N. C. (2000) Nuclear export signal located within the DNA-binding domain of the STAT1 transcription factor. EMBO J. 19, 6196-6206.
-
(2000)
EMBO J.
, vol.19
, pp. 6196-6206
-
-
McBride, K.M.1
McDonald, C.2
Reich, N.C.3
-
138
-
-
0033558170
-
Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins
-
Koster, M., Hauser, H. (1999) Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins. Eur. J. Biochem. 260, 137-144.
-
(1999)
Eur. J. Biochem.
, vol.260
, pp. 137-144
-
-
Koster, M.1
Hauser, H.2
-
139
-
-
0025949412
-
Nuclear targeting sequences - A consensus?
-
Dingwall, C., Laskey, R. A. (1991) Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16, 478-481.
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 478-481
-
-
Dingwall, C.1
Laskey, R.A.2
-
140
-
-
0022466330
-
Transport of gamma-interferon into the cell nucleus may be mediated by nuclear membrane receptors
-
MacDonald, H. S., Kushnaryov, V. M., Sedmak, J. J., Grossberg, S. E. (1986) Transport of gamma-interferon into the cell nucleus may be mediated by nuclear membrane receptors. Biochem. Biophys. Res. Commun. 138, 254-260.
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.138
, pp. 254-260
-
-
MacDonald, H.S.1
Kushnaryov, V.M.2
Sedmak, J.J.3
Grossberg, S.E.4
-
141
-
-
0027999862
-
Nuclear accumulation of interferon gamma
-
Bader, T., Weitzerbin, J. (1994) Nuclear accumulation of interferon gamma. Proc. Natl. Acad. Sci. USA 91, 11831-11835.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11831-11835
-
-
Bader, T.1
Weitzerbin, J.2
-
142
-
-
0032898092
-
The carboxyl terminus of interferon-gamma contains a functional polybasic nuclear localization sequence
-
Subramaniam, P. S., Mujtaba, M. G., Paddy, M. R., Johnson, H. M. (1999) The carboxyl terminus of interferon-gamma contains a functional polybasic nuclear localization sequence. J. Biol. Chem. 274, 403-407.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 403-407
-
-
Subramaniam, P.S.1
Mujtaba, M.G.2
Paddy, M.R.3
Johnson, H.M.4
-
143
-
-
0033841017
-
The COOH-terminal nuclear localization sequence of interferon gamma regulates STAT1 alpha nuclear translocation at an intracellular site
-
Subramaniam, P. S., Larkin III, J., Mujtaba, M. G., Walter, M. R., Johnson, H. M. (2000) The COOH-terminal nuclear localization sequence of interferon gamma regulates STAT1 alpha nuclear translocation at an intracellular site. J. Cell Sci. 113, 2771-2781.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 2771-2781
-
-
Subramaniam, P.S.1
Larkin III, J.2
Mujtaba, M.G.3
Walter, M.R.4
Johnson, H.M.5
-
144
-
-
0025376202
-
Mutational analysis of the C-terminus of human interferon-gamma
-
Wetzel, R., Perry, L. J., Veilleux, C., Chang, G. (1990) Mutational analysis of the C-terminus of human interferon-gamma. Protein Eng. 3, 611-623.
-
(1990)
Protein Eng.
, vol.3
, pp. 611-623
-
-
Wetzel, R.1
Perry, L.J.2
Veilleux, C.3
Chang, G.4
-
145
-
-
0026093103
-
The carboxyl-terminal region of human interferon gamma is important for biological activity: Mutagenic and NMR analysis
-
Lundell, D., Lunn, C., Dalgarno, D., Fossetta, J., Greenberg, R., Reim, R., Grace, M., Narula, S. (1991) The carboxyl-terminal region of human interferon gamma is important for biological activity: mutagenic and NMR analysis. Protein Eng. 4, 335-341.
-
(1991)
Protein Eng.
, vol.4
, pp. 335-341
-
-
Lundell, D.1
Lunn, C.2
Dalgarno, D.3
Fossetta, J.4
Greenberg, R.5
Reim, R.6
Grace, M.7
Narula, S.8
-
146
-
-
0022226321
-
Abrogation of species specificity for activation of tumoricidal properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes
-
Fidler, I. J., Fogler, W. E., Kleinerman, E. S., Saiki, I. (1985) Abrogation of species specificity for activation of tumoricidal properties in macrophages by recombinant mouse or human interferon-gamma encapsulated in liposomes. J. Immunol. 135, 4289-4296.
-
(1985)
J. Immunol.
, vol.135
, pp. 4289-4296
-
-
Fidler, I.J.1
Fogler, W.E.2
Kleinerman, E.S.3
Saiki, I.4
-
147
-
-
0023268584
-
Intracellular human gamma-interferon triggers an antiviral state in transformed murine L cells
-
Sanceau, J., Sondermeyer, P., Beranger, F., Falcoff, R., Vaquero, C. (1987) Intracellular human gamma-interferon triggers an antiviral state in transformed murine L cells. Proc. Natl. Acad. Sci. USA 84, 2906-2910.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 2906-2910
-
-
Sanceau, J.1
Sondermeyer, P.2
Beranger, F.3
Falcoff, R.4
Vaquero, C.5
-
148
-
-
0025374189
-
Direct evidence for an intracellular role for IFN-gamma. Microinjection of human IFN-gamma induces la expression on murine macrophages
-
Smith, M. R., Muegge, K., Keller, J. R., Kung, H. F., Young, H. A., Durum, S. K. (1990) Direct evidence for an intracellular role for IFN-gamma. Microinjection of human IFN-gamma induces la expression on murine macrophages. J. Immunol. 144, 1777-1782.
-
(1990)
J. Immunol.
, vol.144
, pp. 1777-1782
-
-
Smith, M.R.1
Muegge, K.2
Keller, J.R.3
Kung, H.F.4
Young, H.A.5
Durum, S.K.6
-
149
-
-
0035678290
-
Nuclear translocation of IFN-gamma is an intrinsic requirement for its biologic activity and can be driven by a heterologous nuclear localization sequence
-
Subramaniam, P. S., Green, M. M., Larkin III, J., Torres, B. A., Johnson, H. M. (2001) Nuclear translocation of IFN-gamma is an intrinsic requirement for its biologic activity and can be driven by a heterologous nuclear localization sequence. J. Interferon Cytokine Res. 21, 951-959.
-
(2001)
J. Interferon Cytokine Res.
, vol.21
, pp. 951-959
-
-
Subramaniam, P.S.1
Green, M.M.2
Larkin III, J.3
Torres, B.A.4
Johnson, H.M.5
-
150
-
-
0033931384
-
Differential nuclear localization of the IFNGR-1 and IFNGR-2 subunits of the IFN-gamma receptor complex following activation by IFN-gamma
-
Larkin III, J., Johnson, H. M., Subramaniam, P. S. (2000) Differential nuclear localization of the IFNGR-1 and IFNGR-2 subunits of the IFN-gamma receptor complex following activation by IFN-gamma. J. Interferon Cytokine Res. 20, 565-576.
-
(2000)
J. Interferon Cytokine Res.
, vol.20
, pp. 565-576
-
-
Larkin III, J.1
Johnson, H.M.2
Subramaniam, P.S.3
-
151
-
-
0030024563
-
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
-
Durbin, J. E., Hackenmiller, R., Simon, M. C., Levy, D. E. (1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84, 443-450.
-
(1996)
Cell
, vol.84
, pp. 443-450
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
152
-
-
0035810953
-
Stat1-independent regulation of gene expression in response to IFN- gamma
-
Ramana, C. V., Gil, M. P., Han, Y., Ransohoff, R. M., Schreiber, R. D., Stark, G. R. (2001) Stat1-independent regulation of gene expression in response to IFN- gamma. Proc. Natl. Acad. Sci. USA 98, 6674-6679.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6674-6679
-
-
Ramana, C.V.1
Gil, M.P.2
Han, Y.3
Ransohoff, R.M.4
Schreiber, R.D.5
Stark, G.R.6
-
153
-
-
0029799912
-
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
-
Bromberg, J. F., Horvath, C. M., Wen, Z., Schreiber, R. D., Darnell Jr., J. E. (1996) Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc. Natl. Acad. Sci. USA 93, 7673-7678.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7673-7678
-
-
Bromberg, J.F.1
Horvath, C.M.2
Wen, Z.3
Schreiber, R.D.4
Darnell Jr., J.E.5
-
154
-
-
0034677195
-
Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways
-
Ramana, C. V., Grammatikakis, N., Chernov, M., Nguyen, H., Goh, K. C., Williams, B. R., Stark, G. R. (2000) Regulation of c-myc expression by
-
(2000)
EMBO J.
, vol.19
, pp. 263-272
-
-
Ramana, C.V.1
Grammatikakis, N.2
Chernov, M.3
Nguyen, H.4
Goh, K.C.5
Williams, B.R.6
Stark, G.R.7
-
155
-
-
0035811006
-
Biologic consequences of Stat1-independent IFN signaling
-
Gil, M. P., Bohn, E., O'Guin, A. K., Ramana, C. V., Levine, B., Stark, G. R., Virgin, H. W., Schreiber, R. D. (2001) Biologic consequences of Stat1-independent IFN signaling. Proc. Natl. Acad. Sci. USA 98, 6680-6685.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6680-6685
-
-
Gil, M.P.1
Bohn, E.2
O'Guin, A.K.3
Ramana, C.V.4
Levine, B.5
Stark, G.R.6
Virgin, H.W.7
Schreiber, R.D.8
-
156
-
-
0035854542
-
Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation
-
Dupuis, S., Dargemont, C., Fieschi, C., Thomassin, N., Rosenzweig, S., Harris, J., Holland, S. M., Schreiber, R. D., Casanova, J. L. (2001) Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science 293, 300-303.
-
(2001)
Science
, vol.293
, pp. 300-303
-
-
Dupuis, S.1
Dargemont, C.2
Fieschi, C.3
Thomassin, N.4
Rosenzweig, S.5
Harris, J.6
Holland, S.M.7
Schreiber, R.D.8
Casanova, J.L.9
-
157
-
-
0035061538
-
IRF family of transcription factors as regulators of host defense
-
Taniguchi, T., Ogasawara, K., Takaoka, A., Tanaka, N. (2001) IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19, 623-655.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 623-655
-
-
Taniguchi, T.1
Ogasawara, K.2
Takaoka, A.3
Tanaka, N.4
-
158
-
-
0027390602
-
A novel interferon-inducible domain: Structural and functional analysis of the human interferon regulatory factor 1 gene promoter
-
Sims, S. H., Cha, Y., Romine, M. F., Gao, P. Q., Gottlieb, K., Deisseroth, A. B. (1993) A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter. Mol. Cell. Biol. 13, 690-702.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 690-702
-
-
Sims, S.H.1
Cha, Y.2
Romine, M.F.3
Gao, P.Q.4
Gottlieb, K.5
Deisseroth, A.B.6
-
159
-
-
0028032114
-
Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: Implications for a gene network in the interferon system
-
Harada, H., Takahashi, E., Itoh, S., Harada, K., Hori, T. A., Taniguchi, T. (1994) Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system. Mol. Cell. Biol. 14, 1500-1509.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1500-1509
-
-
Harada, H.1
Takahashi, E.2
Itoh, S.3
Harada, K.4
Hori, T.A.5
Taniguchi, T.6
-
160
-
-
0030608917
-
Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element
-
Pine, R. (1997) Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element. Nucleic Acids Res. 25, 4346-4354.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4346-4354
-
-
Pine, R.1
-
161
-
-
0032841028
-
Interferon regulatory factors: The next generation
-
Mamane, Y., Heylbroeck, C., Genin, P., Algarte, M., Servant, M. J., LePage, C., DeLuca, C., Kwon, H., Lin, R., Hiscott, J. (1999) Interferon regulatory factors: the next generation. Gene 237, 1-14.
-
(1999)
Gene
, vol.237
, pp. 1-14
-
-
Mamane, Y.1
Heylbroeck, C.2
Genin, P.3
Algarte, M.4
Servant, M.J.5
LePage, C.6
DeLuca, C.7
Kwon, H.8
Lin, R.9
Hiscott, J.10
-
162
-
-
0033179698
-
IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice
-
Salkowski, C. A., Kopydlowski, K., Blanco, J., Cody, M. J., McNally, R., Vogel, S. N. (1999) IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice. J. Immunol. 163, 1529-1536.
-
(1999)
J. Immunol.
, vol.163
, pp. 1529-1536
-
-
Salkowski, C.A.1
Kopydlowski, K.2
Blanco, J.3
Cody, M.J.4
McNally, R.5
Vogel, S.N.6
-
163
-
-
0030457133
-
The induction of class I and II major histocompatibility complex by allogeneic stimulation is dependent on the transcription factor interferon regulatory factor 1 (IRF-1): Observations in IRF-1 knockout mice
-
Hobart, M., Ramassar, V., Goes, N., Urmson, J., Halloran, P. F. (1996) The induction of class I and II major histocompatibility complex by allogeneic stimulation is dependent on the transcription factor interferon regulatory factor 1 (IRF-1): observations in IRF-1 knockout mice. Transplantation 62, 1895-1901.
-
(1996)
Transplantation
, vol.62
, pp. 1895-1901
-
-
Hobart, M.1
Ramassar, V.2
Goes, N.3
Urmson, J.4
Halloran, P.F.5
-
164
-
-
0027250364
-
Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system
-
Tanaka, N., Kawakami, T., Taniguchi, T. (1993) Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system. Mol. Cell. Biol. 13, 4531-4538.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4531-4538
-
-
Tanaka, N.1
Kawakami, T.2
Taniguchi, T.3
-
165
-
-
0028276685
-
Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1
-
Tanaka, N., Ishihara, M., Kitagawa, M., Harada, H., Kimura, T., Matsuyama, T., Lamphier, M. S., Aizawa, S., Mak, T. W., Taniguchi, T. (1994) Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1. Cell 77, 829-839.
-
(1994)
Cell
, vol.77
, pp. 829-839
-
-
Tanaka, N.1
Ishihara, M.2
Kitagawa, M.3
Harada, H.4
Kimura, T.5
Matsuyama, T.6
Lamphier, M.S.7
Aizawa, S.8
Mak, T.W.9
Taniguchi, T.10
-
166
-
-
0028146097
-
Involvement of the IRF-1 transcription factor in antiviral responses to interferons
-
Kimura, T., Nakayama, K., Penninger, J., Kitagawa, M., Harada, H., Matsuyama, T., Tanaka, N., Kamijo, R., Vilcek, J., Mak, T. W., et al. (1994) Involvement of the IRF-1 transcription factor in antiviral responses to interferons. Science 264, 1921-1924.
-
(1994)
Science
, vol.264
, pp. 1921-1924
-
-
Kimura, T.1
Nakayama, K.2
Penninger, J.3
Kitagawa, M.4
Harada, H.5
Matsuyama, T.6
Tanaka, N.7
Kamijo, R.8
Vilcek, J.9
Mak, T.W.10
-
167
-
-
0028169448
-
IFN-gamma selectively inhibits lipopolysaccharide-inducible JE/monocyte chemoattractant protein-1 and KC/GRO/melanoma growth-stimulating activity gene expression in mouse peritoneal macrophages
-
Ohmori, Y., Hamilton, T. A. (1994) IFN-gamma selectively inhibits lipopolysaccharide-inducible JE/monocyte chemoattractant protein-1 and KC/GRO/melanoma growth-stimulating activity gene expression in mouse peritoneal macrophages. J. Immunol. 153, 2204-2212.
-
(1994)
J. Immunol.
, vol.153
, pp. 2204-2212
-
-
Ohmori, Y.1
Hamilton, T.A.2
-
168
-
-
0028173630
-
Sublocalization of the human interferon-gamma receptor accessory factor gene and characterization of accessory factor activity by yeast artificial chromosomal fragmentation
-
Cook, J. R., Emanuel, S. L., Donnelly, R. J., Soh, J., Mariano, T. M., Schwartz, B., Rhee, S., Pestka, S. (1994) Sublocalization of the human interferon-gamma receptor accessory factor gene and characterization of accessory factor activity by yeast artificial chromosomal fragmentation. J. Biol. Chem. 269, 7013-7018.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7013-7018
-
-
Cook, J.R.1
Emanuel, S.L.2
Donnelly, R.J.3
Soh, J.4
Mariano, T.M.5
Schwartz, B.6
Rhee, S.7
Pestka, S.8
-
169
-
-
0030840464
-
STATs and gene regulation
-
Darnell Jr., J. E. (1997) STATs and gene regulation. Science 277, 1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr., J.E.1
-
170
-
-
0027214809
-
The biology and biochemistry of interferon-gamma and its receptor
-
Schreiber, R. D., Farrar, M. A. (1993) The biology and biochemistry of interferon-gamma and its receptor. Gastroenterol Jpn 28 (Suppl. 4), 88-94.
-
(1993)
Gastroenterol. Jpn.
, vol.28
, Issue.SUPPL. 4
, pp. 88-94
-
-
Schreiber, R.D.1
Farrar, M.A.2
-
171
-
-
0020961799
-
Human interferon-gamma is internalized and degraded by cultured fibroblasts
-
Anderson, P., Yip, Y. K., Vilcek, J. (1983) Human interferon-gamma is internalized and degraded by cultured fibroblasts. J. Biol. Chem. 258, 6497-6502.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 6497-6502
-
-
Anderson, P.1
Yip, Y.K.2
Vilcek, J.3
-
172
-
-
0023258380
-
Internalization and degradation of receptor-bound interferon-gamma by murine macrophages. Demonstration of receptor recycling
-
Celada, A., Schreiber, R. D. (1987) Internalization and degradation of receptor-bound interferon-gamma by murine macrophages. Demonstration of receptor recycling. J. Immunol. 139, 147-153.
-
(1987)
J. Immunol.
, vol.139
, pp. 147-153
-
-
Celada, A.1
Schreiber, R.D.2
-
173
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
Endo, T. A., Masuhara, M., Yokouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., Miyazaki, T., Leonor, N., Taniguchi, T., Fujita, T., Kanakura, Y., Komiya, S., Yoshimura, A. (1997) A new protein containing an SH2 domain that inhibits JAK kinases. Nature 387, 921-924.
-
(1997)
Nature
, vol.387
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yokouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
Matsumoto, A.7
Tanimura, S.8
Ohtsubo, M.9
Misawa, H.10
Miyazaki, T.11
Leonor, N.12
Taniguchi, T.13
Fujita, T.14
Kanakura, Y.15
Komiya, S.16
Yoshimura, A.17
-
174
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
Starr, R., Willson, T. A., Viney, E. M., Murray, L. J., Rayner, J. R., Jenkins, B. J., Gonda, T. J., Alexander, W. S., Metcalf, D., Nicola, N. A., Hilton, D. J. (1997) A family of cytokine-inducible inhibitors of signalling. Nature 387, 917-921.
-
(1997)
Nature
, vol.387
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
Murray, L.J.4
Rayner, J.R.5
Jenkins, B.J.6
Gonda, T.J.7
Alexander, W.S.8
Metcalf, D.9
Nicola, N.A.10
Hilton, D.J.11
-
175
-
-
7844249247
-
CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells
-
Suzuki, R., Sakamoto, H., Yasukawa, H., Masuhara, M., Wakioka, T., Sasaki, A., Yuge, K., Komiya, S., Inoue, A., Yoshimura, A. (1998) CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells. Oncogene 17, 2271-2278.
-
(1998)
Oncogene
, vol.17
, pp. 2271-2278
-
-
Suzuki, R.1
Sakamoto, H.2
Yasukawa, H.3
Masuhara, M.4
Wakioka, T.5
Sasaki, A.6
Yuge, K.7
Komiya, S.8
Inoue, A.9
Yoshimura, A.10
-
176
-
-
0032170490
-
A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons
-
Sakamoto, H., Yasukawa, H., Masuhara, M., Tanimura, S., Sasaki, A., Yuge, K., Ohtsubo, M., Ohtsuka, A., Fujita, T., Ohta, T., Furukawa, Y., Iwase, S., Yamada, H., Yoshimura, A. (1998) A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons. Blood 92, 1668-1676.
-
(1998)
Blood
, vol.92
, pp. 1668-1676
-
-
Sakamoto, H.1
Yasukawa, H.2
Masuhara, M.3
Tanimura, S.4
Sasaki, A.5
Yuge, K.6
Ohtsubo, M.7
Ohtsuka, A.8
Fujita, T.9
Ohta, T.10
Furukawa, Y.11
Iwase, S.12
Yamada, H.13
Yoshimura, A.14
-
177
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
Yasukawa, H., Misawa, H., Sakamoto, H., Masuhara, M., Sasaki, A., Wakioka, T., Ohtsuka, S., Imaizumi, T., Matsuda, T., Ihle, J. N., Yoshimura, A. (1999) The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J. 18, 1309-1320.
-
(1999)
EMBO J.
, vol.18
, pp. 1309-1320
-
-
Yasukawa, H.1
Misawa, H.2
Sakamoto, H.3
Masuhara, M.4
Sasaki, A.5
Wakioka, T.6
Ohtsuka, S.7
Imaizumi, T.8
Matsuda, T.9
Ihle, J.N.10
Yoshimura, A.11
-
178
-
-
13044263097
-
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
-
Zhang, J. G., Farley, A., Nicholson, S. E., Willson, T. A., Zugaro, L. M., Simpson, R. J., Moritz, R. L., Cary, D., Richardson, R., Hausmann, G., Kile, B. J., Kent, S. B., Alexander, W. S., Metcalf, D., Hilton, D. J., Nicola, N. A., Baca, M. (1999) The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. Proc. Natl. Acad. Sci. USA 96, 2071-2076.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2071-2076
-
-
Zhang, J.G.1
Farley, A.2
Nicholson, S.E.3
Willson, T.A.4
Zugaro, L.M.5
Simpson, R.J.6
Moritz, R.L.7
Cary, D.8
Richardson, R.9
Hausmann, G.10
Kile, B.J.11
Kent, S.B.12
Alexander, W.S.13
Metcalf, D.14
Hilton, D.J.15
Nicola, N.A.16
Baca, M.17
-
179
-
-
0034663932
-
Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice
-
Fujimoto, M., Naka, T., Nakagawa, R., Kawazoe, Y., Morita, Y., Tateishi, A., Okumura, K., Narazaki, M., Kishimoto, T. (2000) Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice. J. Immunol. 165, 1799-1806.
-
(2000)
J. Immunol.
, vol.165
, pp. 1799-1806
-
-
Fujimoto, M.1
Naka, T.2
Nakagawa, R.3
Kawazoe, Y.4
Morita, Y.5
Tateishi, A.6
Okumura, K.7
Narazaki, M.8
Kishimoto, T.9
-
180
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
-
Alexander, W. S., Starr, R., Fenner, J. E., Scott, C. L., Handman, E., Sprigg, N. S., Corbin, J. E., Cornish, A. L., Darwiche, R., Owczarek, C. M., Kay, T. W., Nicola, N. A. Hertzog, P. J., Metcalf, D., Hilton, D. J. (1999) SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98, 597-608.
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
Starr, R.2
Fenner, J.E.3
Scott, C.L.4
Handman, E.5
Sprigg, N.S.6
Corbin, J.E.7
Cornish, A.L.8
Darwiche, R.9
Owczarek, C.M.10
Kay, T.W.11
Nicola, N.A.12
Hertzog, P.J.13
Metcalf, D.14
Hilton, D.J.15
-
181
-
-
0033520467
-
SOCSI deficiency causes a lymphocyte-dependent perinatal lethality
-
Marine, J. C., Topham, D. J., McKay, C., Wang, D., Parganas, E., Stravopodis, D., Yoshimura, A., Ihle, J. N. (1999) SOCSI deficiency causes a lymphocyte-dependent perinatal lethality. Cell 98, 609-616.
-
(1999)
Cell
, vol.98
, pp. 609-616
-
-
Marine, J.C.1
Topham, D.J.2
McKay, C.3
Wang, D.4
Parganas, E.5
Stravopodis, D.6
Yoshimura, A.7
Ihle, J.N.8
-
182
-
-
0032567353
-
The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities
-
Song, M. M., Shuai, K. (1998) The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities. J. Biol. Chem. 273, 35056-35062.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 35056-35062
-
-
Song, M.M.1
Shuai, K.2
-
183
-
-
0030795790
-
Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1
-
Haque, S. J., Wu, Q., Kammer, W., Friedrich, K., Smith, J. M., Kerr, I. M., Stark, G. R., Williams, B. R. (1997) Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1. Proc. Natl. Acad. Sci. USA 94, 8563-8568.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8563-8568
-
-
Haque, S.J.1
Wu, Q.2
Kammer, W.3
Friedrich, K.4
Smith, J.M.5
Kerr, I.M.6
Stark, G.R.7
Williams, B.R.8
-
184
-
-
0032980574
-
Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway
-
You, M., Yu, D. H., Feng, G. S. (1999) Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway. Mol. Cell. Biol. 19, 2416-2424.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2416-2424
-
-
You, M.1
Yu, D.H.2
Feng, G.S.3
-
185
-
-
0031012543
-
Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney
-
Ruff, S. J., Chen, K., Cohen, S. (1997) Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney. J. Biol. Chem. 272, 1263-1267.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1263-1267
-
-
Ruff, S.J.1
Chen, K.2
Cohen, S.3
-
186
-
-
0028972719
-
Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1
-
David, M., Chen, H. E., Goelz, S., Larner, A. C., Neel, B. G. (1995) Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1. Mol. Cell. Biol. 15, 7050-7058.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 7050-7058
-
-
David, M.1
Chen, H.E.2
Goelz, S.3
Larner, A.C.4
Neel, B.G.5
-
187
-
-
0034614626
-
Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation
-
Yu, C. L., Jin, Y. J., Burakoff, S. J. (2000) Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation. J. Biol. Chem. 275, 599-604.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 599-604
-
-
Yu, C.L.1
Jin, Y.J.2
Burakoff, S.J.3
-
188
-
-
0027197067
-
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
-
Shultz, L. D., Schweitzer, P. A., Rajan, T. V., Yi, T., Ihle, J. N., Matthews, R. J., Thomas, M. L., Beier, D. R. (1993) Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73, 1445-1454.
-
(1993)
Cell
, vol.73
, pp. 1445-1454
-
-
Shultz, L.D.1
Schweitzer, P.A.2
Rajan, T.V.3
Yi, T.4
Ihle, J.N.5
Matthews, R.J.6
Thomas, M.L.7
Beier, D.R.8
-
189
-
-
0033826549
-
Regulation of STAT1 nuclear export by Jak1
-
Mowen, K., David, M. (2000) Regulation of STAT1 nuclear export by Jak1. Mol. Cell. Biol. 20, 7273-7281.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7273-7281
-
-
Mowen, K.1
David, M.2
-
190
-
-
0030924190
-
CRM1 is an export receptor for leucine-rich nuclear export signals
-
Fornerod, M., Ohno, M., Yoshida, M., Mattaj, I. W. (1997) CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 90, 1051-1060.
-
(1997)
Cell
, vol.90
, pp. 1051-1060
-
-
Fornerod, M.1
Ohno, M.2
Yoshida, M.3
Mattaj, I.W.4
-
191
-
-
0030985459
-
Exportin 1 (Crm1p) is an essential nuclear export factor
-
Stade, K., Ford, C. S., Guthrie, C., Weis, K. (1997) Exportin 1 (Crm1p) is an essential nuclear export factor. Cell 90, 1041-1050.
-
(1997)
Cell
, vol.90
, pp. 1041-1050
-
-
Stade, K.1
Ford, C.S.2
Guthrie, C.3
Weis, K.4
-
192
-
-
0033621066
-
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1
-
Haspel, R. L., Darnell Jr., J. E. (1999) A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1. Proc. Natl. Acad. Sci. USA 96, 10188-10193.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10188-10193
-
-
Haspel, R.L.1
Darnell Jr., J.E.2
-
193
-
-
0029972194
-
The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
-
Haspel, R. L., Salditt-Georgieff, M., Darnell Jr., J. E. (1996) The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J. 15, 6262-6268.
-
(1996)
EMBO J.
, vol.15
, pp. 6262-6268
-
-
Haspel, R.L.1
Salditt-Georgieff, M.2
Darnell Jr., J.E.3
-
194
-
-
0027494653
-
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction
-
Muller, M., Briscoe, J., Laxton, C., Guschin, D., Ziemiecki, A., Silvennoinen, O., Harpur, A. G., Barbieri, G., Witthuhn, B. A., Schindler, C., et al. (1993) The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction. Nature 366, 129-135.
-
(1993)
Nature
, vol.366
, pp. 129-135
-
-
Muller, M.1
Briscoe, J.2
Laxton, C.3
Guschin, D.4
Ziemiecki, A.5
Silvennoinen, O.6
Harpur, A.G.7
Barbieri, G.8
Witthuhn, B.A.9
Schindler, C.10
-
195
-
-
0027914818
-
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway
-
Watling, D., Guschin, D., Muller, M., Silvennoinen, O., Witthuhn, B. A., Quelle, F. W., Rogers, N. C., Schindler, C., Stark, G. R., Ihle, J. N., et al. (1993) Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway. Nature 366, 166-170.
-
(1993)
Nature
, vol.366
, pp. 166-170
-
-
Watling, D.1
Guschin, D.2
Muller, M.3
Silvennoinen, O.4
Witthuhn, B.A.5
Quelle, F.W.6
Rogers, N.C.7
Schindler, C.8
Stark, G.R.9
Ihle, J.N.10
-
196
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig, S. J., Meraz, M. A., White, J. M., Lampe, P. A., Riley, J. K., Arthur, C. D., King, K. L., Sheehan, K. C., Yin, L., Pennica, D., Johnson Jr., E. M., Schreiber, R. D. (1998) Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 93, 373-383.
-
(1998)
Cell
, vol.93
, pp. 373-383
-
-
Rodig, S.J.1
Meraz, M.A.2
White, J.M.3
Lampe, P.A.4
Riley, J.K.5
Arthur, C.D.6
King, K.L.7
Sheehan, K.C.8
Yin, L.9
Pennica, D.10
Johnson Jr., E.M.11
Schreiber, R.D.12
-
197
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
Parganas, E., Wang, D., Stravopodis, D., Topham, D. J., Marine, J. C., Teglund, S., Vanin, E. F., Bodner, S., Colamonici, O. R., van Deursen, J. M., Grosveld, G., Ihle, J. N. (1998) Jak2 is essential for signaling through a variety of cytokine receptors. Cell 93, 385-395.
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
Topham, D.J.4
Marine, J.C.5
Teglund, S.6
Vanin, E.F.7
Bodner, S.8
Colamonici, O.R.9
Van Deursen, J.M.10
Grosveld, G.11
Ihle, J.N.12
-
198
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer, H., Cumano, A., Muller, M., Wu, H., Huffstadt, U., Pfeffer, K. (1998) Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 93, 397-409.
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumano, A.2
Muller, M.3
Wu, H.4
Huffstadt, U.5
Pfeffer, K.6
-
199
-
-
0030016180
-
Other kinases can substitute for Jak2 in signal transduction by interferon-gamma
-
Kotenko, S. V., Izotova, L. S., Pollack, B. P., Muthukumaran, G., Paukku, K., Silvennoinen, O., Ihle, J. N., Pestka, S. (1996) Other kinases can substitute for Jak2 in signal transduction by interferon-gamma. J. Biol. Chem. 271, 17174-17182.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17174-17182
-
-
Kotenko, S.V.1
Izotova, L.S.2
Pollack, B.P.3
Muthukumaran, G.4
Paukku, K.5
Silvennoinen, O.6
Ihle, J.N.7
Pestka, S.8
-
200
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan, M. H., Sun, Y. L., Hoey, T., Grusby, M. J. (1996) Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382, 174-177.
-
(1996)
Nature
, vol.382
, pp. 174-177
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
Grusby, M.J.4
-
201
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder, W. E., van Deursen, J. M., Yamamoto, K., Tripp, R. A., Sarawar, S. R., Carson, R. T., Sangster, M. Y., Vignali, D. A., Doherty, P. C., Grosveld, G. C., Ihle, J. N. (1996) Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382, 171-174.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
Van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.8
Doherty, P.C.9
Grosveld, G.C.10
Ihle, J.N.11
-
202
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda, K., Tanaka, T., Shi, W., Matsumoto, M., Minami, M., Kashiwamura, S., Nakanishi, K., Yoshida, N., Kishimoto, T., Akira, S. (1996) Essential role of Stat6 in IL-4 signalling. Nature 380, 627-630.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
203
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda, K., van Deursen, J., Sangster, M. Y., Sarawar, S. R., Carson, R. T., Tripp, R. A., Chu, C., Quelle, F. W., Nosaka, T., Vignali, D. A., Doherty, P. C., Grosveld, G., Paul, W. E., Ihle, J. N. (1996) Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380, 630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.10
Doherty, P.C.11
Grosveld, G.12
Paul, W.E.13
Ihle, J.N.14
-
204
-
-
0031057929
-
Stat5a is mandatory for adult mammary gland development and lactogenesis
-
Liu, X., Robinson, G. W., Wagner, K. U., Garrett, L., Wynshaw-Boris, A., Hennighausen, L. (1997) Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev. 11, 179-186.
-
(1997)
Genes Dev.
, vol.11
, pp. 179-186
-
-
Liu, X.1
Robinson, G.W.2
Wagner, K.U.3
Garrett, L.4
Wynshaw-Boris, A.5
Hennighausen, L.6
-
205
-
-
0032213273
-
Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
-
Takeda, K., Kaisho, T., Yoshida, N., Takeda, J., Kishimoto, T., Akira, S. (1998) Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J. Immunol. 161, 4652-4660.
-
(1998)
J. Immunol.
, vol.161
, pp. 4652-4660
-
-
Takeda, K.1
Kaisho, T.2
Yoshida, N.3
Takeda, J.4
Kishimoto, T.5
Akira, S.6
-
206
-
-
0028910289
-
Possible involvement of the transcription factor ISGF3 gamma in virus-induced expression of the IFN-beta gene
-
Kawakami, T., Matsumoto, M., Sato, M., Harada, H., Taniguchi, T., Kitagawa, M. (1995) Possible involvement of the transcription factor ISGF3 gamma in virus-induced expression of the IFN-beta gene. FEBS Lett. 358, 225-229.
-
(1995)
FEBS Lett.
, vol.358
, pp. 225-229
-
-
Kawakami, T.1
Matsumoto, M.2
Sato, M.3
Harada, H.4
Taniguchi, T.5
Kitagawa, M.6
-
207
-
-
0029780472
-
Autocrine amplification of type I interferon gene expression mediated by interferon stimulated gene factor 3 (ISGF3)
-
Yoneyama, M., Suhara, W., Fukuhara, Y., Sato, M., Ozato, K., Fujita, T. (1996) Autocrine amplification of type I interferon gene expression mediated by interferon stimulated gene factor 3 (ISGF3). J. Biochem. (Tokyo) 120, 160-169.
-
(1996)
J. Biochem. (Tokyo)
, vol.120
, pp. 160-169
-
-
Yoneyama, M.1
Suhara, W.2
Fukuhara, Y.3
Sato, M.4
Ozato, K.5
Fujita, T.6
-
208
-
-
0032547850
-
Interferon induction of TAP1: The phosphatase SHP-1 regulates crossover between the IFN-alpha/beta and the IFN-gamma signal-transduction pathways
-
Min, W., Pober, J. S., Johnson, D. R. (1998) Interferon induction of TAP1: the phosphatase SHP-1 regulates crossover between the IFN-alpha/beta and the IFN-gamma signal-transduction pathways. Circ. Res. 83, 815-823.
-
(1998)
Circ. Res.
, vol.83
, pp. 815-823
-
-
Min, W.1
Pober, J.S.2
Johnson, D.R.3
-
209
-
-
0034733672
-
Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains
-
Takaoka, A., Mitani, Y., Suemori, H., Sato, M., Yokochi, T., Noguchi, S., Tanaka, N., Taniguchi, T. (2000) Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains. Science 288, 2357-2360.
-
(2000)
Science
, vol.288
, pp. 2357-2360
-
-
Takaoka, A.1
Mitani, Y.2
Suemori, H.3
Sato, M.4
Yokochi, T.5
Noguchi, S.6
Tanaka, N.7
Taniguchi, T.8
-
210
-
-
0028500190
-
Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins
-
Belich, M. P., Glynne, R. J., Senger, G., Sheer, D., Trowsdale, J. (1994) Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins. Curr. Biol. 4, 769-776.
-
(1994)
Curr. Biol.
, vol.4
, pp. 769-776
-
-
Belich, M.P.1
Glynne, R.J.2
Senger, G.3
Sheer, D.4
Trowsdale, J.5
-
211
-
-
0026070217
-
Second proteasome-related gene in the human MHC class II region
-
Kelly, A., Powis, S. H., Glynne, R., Radley, E., Beck, S., Trowsdale, J. (1991) Second proteasome-related gene in the human MHC class II region. Nature 353, 667-668.
-
(1991)
Nature
, vol.353
, pp. 667-668
-
-
Kelly, A.1
Powis, S.H.2
Glynne, R.3
Radley, E.4
Beck, S.5
Trowsdale, J.6
-
212
-
-
0029993775
-
A third interferon-gamma-induced subunit exchange in the 20S proteasome
-
Groettrup, M., Kraft, R., Kostka, S., Standera, S., Stohwasser, R., Kloetzel, P. M. (1996) A third interferon-gamma-induced subunit exchange in the 20S proteasome. Eur. J. Immunol. 26, 863-869.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 863-869
-
-
Groettrup, M.1
Kraft, R.2
Kostka, S.3
Standera, S.4
Stohwasser, R.5
Kloetzel, P.M.6
-
213
-
-
0029878931
-
Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit
-
Nandi, D., Jiang, H., Monaco, J. J. (1996) Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit. J. Immunol. 156, 2361-2364.
-
(1996)
J. Immunol.
, vol.156
, pp. 2361-2364
-
-
Nandi, D.1
Jiang, H.2
Monaco, J.J.3
-
214
-
-
0029911690
-
Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma
-
Hisamatsu, H., Shimbara, N., Saito, Y., Kristensen, P., Hendil, K. B., Fujiwara, T., Takahashi, E., Tanahashi, N., Tamura, T., Ichihara, A., Tanaka, K. (1996) Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma. J. Exp. Med. 183, 1807-1816.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1807-1816
-
-
Hisamatsu, H.1
Shimbara, N.2
Saito, Y.3
Kristensen, P.4
Hendil, K.B.5
Fujiwara, T.6
Takahashi, E.7
Tanahashi, N.8
Tamura, T.9
Ichihara, A.10
Tanaka, K.11
-
215
-
-
17944381636
-
A completely foreign receptor can mediate an interferon-gamma-like response
-
Strobl, B., Arulampalam, V., Is'harc, H., Newman, S. J., Schlaak, J. F., Watling, D., Costa-Pereira, A. P., Schaper, F., Behrmann, I., Sheehan, K. C., Schreiber, R. D., Horn, F., Heinrich, P. C., Kerr, I. M. (2001) A completely foreign receptor can mediate an interferon-gamma-like response. EMBO J. 20, 5431-5442.
-
(2001)
EMBO J.
, vol.20
, pp. 5431-5442
-
-
Strobl, B.1
Arulampalam, V.2
Is'harc, H.3
Newman, S.J.4
Schlaak, J.F.5
Watling, D.6
Costa-Pereira, A.P.7
Schaper, F.8
Behrmann, I.9
Sheehan, K.C.10
Schreiber, R.D.11
Horn, F.12
Heinrich, P.C.13
Kerr, I.M.14
-
216
-
-
0035067590
-
Interferon-gamma inducible exchanges of 20S proteasome active site subunits: Why?
-
Groettrup, M., Khan, S., Schwarz, K., Schmidtke, G. (2001) Interferon-gamma inducible exchanges of 20S proteasome active site subunits: why? Biochimie 83, 367-372.
-
(2001)
Biochimie
, vol.83
, pp. 367-372
-
-
Groettrup, M.1
Khan, S.2
Schwarz, K.3
Schmidtke, G.4
-
217
-
-
0030602834
-
Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands
-
Dick, T. P., Ruppert, T., Groettrup, M., Kloetzel, P. M., Kuehn, L., Koszinowski, U. H., Stevanovic, S., Schild, H., Rammensee, H. G. (1996) Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands. Cell 86, 253-262.
-
(1996)
Cell
, vol.86
, pp. 253-262
-
-
Dick, T.P.1
Ruppert, T.2
Groettrup, M.3
Kloetzel, P.M.4
Kuehn, L.5
Koszinowski, U.H.6
Stevanovic, S.7
Schild, H.8
Rammensee, H.G.9
-
218
-
-
0029918289
-
A role for the proteasome regulator PA28alpha in antigen presentation
-
Groettrup, M., Soza, A., Eggers, M., Kuehn, L., Dick, T. P., Schild, H., Rammensee, H. G., Koszinowski, U. H., Kloetzel, P. M. (1996) A role for the proteasome regulator PA28alpha in antigen presentation. Nature 381, 166-168.
-
(1996)
Nature
, vol.381
, pp. 166-168
-
-
Groettrup, M.1
Soza, A.2
Eggers, M.3
Kuehn, L.4
Dick, T.P.5
Schild, H.6
Rammensee, H.G.7
Koszinowski, U.H.8
Kloetzel, P.M.9
-
219
-
-
0028097823
-
Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes
-
Boes, B., Hengel, H., Ruppert, T., Multhaup, G., Koszinowski, U. H., Kloetzel, P. M. (1994) Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes. J. Exp. Med. 179, 901-909.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 901-909
-
-
Boes, B.1
Hengel, H.2
Ruppert, T.3
Multhaup, G.4
Koszinowski, U.H.5
Kloetzel, P.M.6
-
220
-
-
0025688348
-
Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters
-
Trowsdale, J., Hanson, I., Mockridge, I., Beck, S., Townsend, A., Kelly, A. (1990) Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature 348, 741-744.
-
(1990)
Nature
, vol.348
, pp. 741-744
-
-
Trowsdale, J.1
Hanson, I.2
Mockridge, I.3
Beck, S.4
Townsend, A.5
Kelly, A.6
-
221
-
-
0026468645
-
Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells
-
Epperson, D. E., Arnold, D., Spies, T., Cresswell, P., Pober, J. S., Johnson, D. R. (1992) Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells. J. Immunol. 149, 3297-3301.
-
(1992)
J. Immunol.
, vol.149
, pp. 3297-3301
-
-
Epperson, D.E.1
Arnold, D.2
Spies, T.3
Cresswell, P.4
Pober, J.S.5
Johnson, D.R.6
-
222
-
-
0036108577
-
IFNs and STATs in innate immunity to microorganisms
-
Decker, T., Stockinger, S., Karaghiosoff, M., Muller, M., Kovarik, P. (2002) IFNs and STATs in innate immunity to microorganisms. J. Clin. Invest. 109, 1271-1277.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1271-1277
-
-
Decker, T.1
Stockinger, S.2
Karaghiosoff, M.3
Muller, M.4
Kovarik, P.5
-
223
-
-
0034665302
-
Synergistic induction of the Tap-1 gene by IFN-gamma and lipopolysaccharide in macrophages is regulated by STAT1
-
Cramer, L. A., Nelson, S. L., Klemsz, M. J. (2000) Synergistic induction of the Tap-1 gene by IFN-gamma and lipopolysaccharide in macrophages is regulated by STAT1. J. Immunol. 165, 3190-3197.
-
(2000)
J. Immunol.
, vol.165
, pp. 3190-3197
-
-
Cramer, L.A.1
Nelson, S.L.2
Klemsz, M.J.3
-
224
-
-
1842809115
-
Interferon-induced transcription of a major histocompatibility class I gene accompanies binding of inducible nuclear factors to the interferon consensus sequence
-
Shirayoshi, Y., Burke, P. A., Appella, E., Ozato, K. (1988) Interferon-induced transcription of a major histocompatibility class I gene accompanies binding of inducible nuclear factors to the interferon consensus sequence. Proc. Natl. Acad. Sci. USA 85, 5884-5888.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5884-5888
-
-
Shirayoshi, Y.1
Burke, P.A.2
Appella, E.3
Ozato, K.4
-
225
-
-
0023159806
-
Interferons and their actions
-
Pestka, S., Langer, J. A., Zoon, K. C., Samuel, C. E. (1987) Interferons and their actions. Annu. Rev. Biochem. 56, 727-777.
-
(1987)
Annu. Rev. Biochem.
, vol.56
, pp. 727-777
-
-
Pestka, S.1
Langer, J.A.2
Zoon, K.C.3
Samuel, C.E.4
-
226
-
-
0022455621
-
Noncytocidal mechanisms of action of tumor necrosis factor-alpha on human tumor cells: Enhancement of HLA gene expression synergistic with interferon-gamma
-
Scheurich, P., Kronke, M., Schluter, C., Ucer, U., Pfizenmaier, K. (1986) Noncytocidal mechanisms of action of tumor necrosis factor-alpha on human tumor cells: enhancement of HLA gene expression synergistic with interferon-gamma. Immunobiology 172, 291-300.
-
(1986)
Immunobiology
, vol.172
, pp. 291-300
-
-
Scheurich, P.1
Kronke, M.2
Schluter, C.3
Ucer, U.4
Pfizenmaier, K.5
-
227
-
-
0025357775
-
Tumor necrosis factor and immune interferon synergistically increase transcription of HLA class I heavy- and light-chain genes in vascular endothelium
-
Johnson, D. R., Pober, J. S. (1990) Tumor necrosis factor and immune interferon synergistically increase transcription of HLA class I heavy- and light-chain genes in vascular endothelium. Proc. Natl. Acad. Sci. USA 87, 5183-5187.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5183-5187
-
-
Johnson, D.R.1
Pober, J.S.2
-
228
-
-
0026500204
-
Critical role of a common transcription factor, IRF-1, in the regulation of IFN-beta and IFN-inducible genes
-
Reis, L. F., Harada, H., Wolchok, J. D., Taniguchi, T., Vilcek, J. (1992) Critical role of a common transcription factor, IRF-1, in the regulation of IFN-beta and IFN-inducible genes. EMBO J. 11, 185-193.
-
(1992)
EMBO J.
, vol.11
, pp. 185-193
-
-
Reis, L.F.1
Harada, H.2
Wolchok, J.D.3
Taniguchi, T.4
Vilcek, J.5
-
229
-
-
0026516434
-
The activation of major histocompatibility complex class I genes by interferon regulatory factor-1 (IRF-1)
-
Chang, C. H., Hammer, J., Loh, J. E., Fodor, W. L., Flavell, R. A. (1992) The activation of major histocompatibility complex class I genes by interferon regulatory factor-1 (IRF-1). Immunogenetics 35, 378-384.
-
(1992)
Immunogenetics
, vol.35
, pp. 378-384
-
-
Chang, C.H.1
Hammer, J.2
Loh, J.E.3
Fodor, W.L.4
Flavell, R.A.5
-
230
-
-
0019929408
-
Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells
-
Wallach, D., Fellous, M., Revel, M. (1982) Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells. Nature 299, 833-836.
-
(1982)
Nature
, vol.299
, pp. 833-836
-
-
Wallach, D.1
Fellous, M.2
Revel, M.3
-
231
-
-
0020450948
-
Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells
-
Fellous, M., Nir, U., Wallach, D., Merlin, G., Rubinstein, M., Revel, M. (1982) Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 79, 3082-3086.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 3082-3086
-
-
Fellous, M.1
Nir, U.2
Wallach, D.3
Merlin, G.4
Rubinstein, M.5
Revel, M.6
-
232
-
-
0032611410
-
Cytokines are critical in linking the innate and adaptive immune responses to bacterial, fungal, and parasitic infection
-
Seder, R. A., Gazzinelli, R. T. (1999) Cytokines are critical in linking the innate and adaptive immune responses to bacterial, fungal, and parasitic infection. Adv. Intern. Med. 44, 353-388.
-
(1999)
Adv. Intern. Med.
, vol.44
, pp. 353-388
-
-
Seder, R.A.1
Gazzinelli, R.T.2
-
233
-
-
0035137084
-
Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines
-
Seliger, B., Schreiber, K., Delp, K., Meissner, M., Hammers, S., Reichert, T., Pawlischko, K., Tampe, R., Huber, C. (2001) Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines. Tissue Antigens 57, 39-45.
-
(2001)
Tissue Antigens
, vol.57
, pp. 39-45
-
-
Seliger, B.1
Schreiber, K.2
Delp, K.3
Meissner, M.4
Hammers, S.5
Reichert, T.6
Pawlischko, K.7
Tampe, R.8
Huber, C.9
-
234
-
-
0029877668
-
Regulation of MHC class II genes: Lessons from a disease
-
Mach, B., Steimle, V., Martinez-Soria, E., Reith, W. (1996) Regulation of MHC class II genes: lessons from a disease. Annu. Rev. Immunol. 14, 301-331.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 301-331
-
-
Mach, B.1
Steimle, V.2
Martinez-Soria, E.3
Reith, W.4
-
235
-
-
0029132892
-
The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes
-
Kern, I., Steimle, V., Siegrist, C. A., Mach, B. (1995) The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes. Int. Immunol. 7, 1295-1299.
-
(1995)
Int. Immunol.
, vol.7
, pp. 1295-1299
-
-
Kern, I.1
Steimle, V.2
Siegrist, C.A.3
Mach, B.4
-
236
-
-
0024316785
-
Molecular mechanisms regulating the expression of class II histocompatibility molecules on macrophages. Effects of inductive and suppressive signals on gene transcription
-
Figueiredo, F., Koerner, T. J., Adams, D. O. (1989) Molecular mechanisms regulating the expression of class II histocompatibility molecules on macrophages. Effects of inductive and suppressive signals on gene transcription. J. Immunol. 143, 3781-3786.
-
(1989)
J. Immunol.
, vol.143
, pp. 3781-3786
-
-
Figueiredo, F.1
Koerner, T.J.2
Adams, D.O.3
-
237
-
-
0028924986
-
Class II transactivator regulates the expression of multiple genes involved in antigen presentation
-
Chang, C. H., Flavell, R. A. (1995) Class II transactivator regulates the expression of multiple genes involved in antigen presentation. J. Exp. Med. 181, 765-767.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 765-767
-
-
Chang, C.H.1
Flavell, R.A.2
-
238
-
-
0028313992
-
Assembly, transport, and function of MHC class II molecules
-
Cresswell, P. (1994) Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12, 259-293.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 259-293
-
-
Cresswell, P.1
-
239
-
-
0029615496
-
How MHC class II molecules acquire peptide cargo: Biosynthesis and trafficking through the endocytic pathway
-
Wolf, P. R., Ploegh, H. L. (1995) How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway. Annu. Rev. Cell Dev. Biol. 11, 267-306.
-
(1995)
Annu. Rev. Cell Dev. Biol.
, vol.11
, pp. 267-306
-
-
Wolf, P.R.1
Ploegh, H.L.2
-
240
-
-
0028904111
-
Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages
-
Lah, T. T., Hawley, M., Rock, K. L., Goldberg, A. L. (1995) Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages. FEBS Lett. 363, 85-89.
-
(1995)
FEBS Lett.
, vol.363
, pp. 85-89
-
-
Lah, T.T.1
Hawley, M.2
Rock, K.L.3
Goldberg, A.L.4
-
241
-
-
0028936712
-
IFN-gamma increases cathepsin H mRNA levels in mouse macrophages
-
Lafuse, W. P., Brown, D., Castle, L., Zwilling, B. S. (1995) IFN-gamma increases cathepsin H mRNA levels in mouse macrophages. J. Leukoc. Biol. 57, 663-669.
-
(1995)
J. Leukoc. Biol.
, vol.57
, pp. 663-669
-
-
Lafuse, W.P.1
Brown, D.2
Castle, L.3
Zwilling, B.S.4
-
242
-
-
0025298202
-
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
-
Meurs, E., Chong, K., Galabru, J., Thomas, N. S., Kerr, I. M., Williams, B. R., Hovanessian, A. G. (1990) Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62, 379-390.
-
(1990)
Cell
, vol.62
, pp. 379-390
-
-
Meurs, E.1
Chong, K.2
Galabru, J.3
Thomas, N.S.4
Kerr, I.M.5
Williams, B.R.6
Hovanessian, A.G.7
-
243
-
-
0033621619
-
NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase
-
Zamanian-Daryoush, M., Mogensen, T. H., DiDonato, J. A., Williams, B. R. (2000) NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase. Mol. Cell. Biol. 20, 1278-1290.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1278-1290
-
-
Zamanian-Daryoush, M.1
Mogensen, T.H.2
DiDonato, J.A.3
Williams, B.R.4
-
244
-
-
0033572827
-
A cis-acting element in the 3′-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR
-
Osman, F., Jarrous, N., Ben-Asouli, Y., Kaempfer, R. (1999) A cis-acting element in the 3′-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR. Genes Dev. 13, 3280-3293.
-
(1999)
Genes Dev.
, vol.13
, pp. 3280-3293
-
-
Osman, F.1
Jarrous, N.2
Ben-Asouli, Y.3
Kaempfer, R.4
-
245
-
-
0033541366
-
Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression
-
Donze, O., Dostie, J., Sonenberg, N. (1999) Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression. Virology 256, 322-329.
-
(1999)
Virology
, vol.256
, pp. 322-329
-
-
Donze, O.1
Dostie, J.2
Sonenberg, N.3
-
246
-
-
0032404120
-
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling
-
Balachandran, S., Kim, C. N., Yeh, W. C., Mak, T. W., Bhalla, K., Barber, G. N. (1998) Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling. EMBO J. 17, 6888-6902.
-
(1998)
EMBO J.
, vol.17
, pp. 6888-6902
-
-
Balachandran, S.1
Kim, C.N.2
Yeh, W.C.3
Mak, T.W.4
Bhalla, K.5
Barber, G.N.6
-
247
-
-
0343852938
-
Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways
-
Wong, A. H., Tam, N. W., Yang, Y. L., Cuddihy, A. R., Li, S., Kirchhoff, S., Hauser, H., Decker, T., Koromilas, A. E. (1997) Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways. EMBO J. 16, 1291-1304.
-
(1997)
EMBO J.
, vol.16
, pp. 1291-1304
-
-
Wong, A.H.1
Tam, N.W.2
Yang, Y.L.3
Cuddihy, A.R.4
Li, S.5
Kirchhoff, S.6
Hauser, H.7
Decker, T.8
Koromilas, A.E.9
-
248
-
-
0029135283
-
Mechanism of interferon action: Double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons
-
Patterson, J. B., Thomis, D. C., Hans, S. L., Samuel, C. E. (1995) Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons. Virology 210, 508-511.
-
(1995)
Virology
, vol.210
, pp. 508-511
-
-
Patterson, J.B.1
Thomis, D.C.2
Hans, S.L.3
Samuel, C.E.4
-
249
-
-
0033616531
-
Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus
-
Anderson, S. L., Carton, J. M., Lou, J., Xing, L., Rubin, B. Y. (1999) Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus. Virology 256, 8-14.
-
(1999)
Virology
, vol.256
, pp. 8-14
-
-
Anderson, S.L.1
Carton, J.M.2
Lou, J.3
Xing, L.4
Rubin, B.Y.5
-
250
-
-
0033652395
-
Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: Implications for different functions?
-
Vestal, D. J., Gorbacheva, V. Y., Sen, G. C. (2000) Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions? J. Interferon Cytokine Res. 20, 991-1000.
-
(2000)
J. Interferon Cytokine Res.
, vol.20
, pp. 991-1000
-
-
Vestal, D.J.1
Gorbacheva, V.Y.2
Sen, G.C.3
-
251
-
-
0029817929
-
Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons
-
Raveh, T., Hovanessian, A. G., Meurs, E. F., Sonenberg, N., Kimchi, A. (1996) Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons. J. Biol. Chem. 271, 25479-25484.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25479-25484
-
-
Raveh, T.1
Hovanessian, A.G.2
Meurs, E.F.3
Sonenberg, N.4
Kimchi, A.5
-
252
-
-
0033166302
-
Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis
-
Xaus, J., Cardo, M., Valledor, A. F., Soler, C., Lloberas, J., Celada, A. (1999) Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis. Immunity 11, 103-113.
-
(1999)
Immunity
, vol.11
, pp. 103-113
-
-
Xaus, J.1
Cardo, M.2
Valledor, A.F.3
Soler, C.4
Lloberas, J.5
Celada, A.6
-
253
-
-
0030611391
-
The role of p27Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells
-
Harvat, B. L., Seth, P., Jetten, A. M. (1997) The role of p27Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells. Oncogene 14, 2111-2122.
-
(1997)
Oncogene
, vol.14
, pp. 2111-2122
-
-
Harvat, B.L.1
Seth, P.2
Jetten, A.M.3
-
254
-
-
0033035537
-
Interferon-gamma impairs physiologic downregulation of cyclin-dependent kinase inhibitor, p27Kip1, during G1 phase progression in macrophages
-
Matsuoka, M., Nishimoto, I., Asano, S. (1999) Interferon-gamma impairs physiologic downregulation of cyclin-dependent kinase inhibitor, p27Kip1, during G1 phase progression in macrophages. Exp. Hematol. 27, 203-209.
-
(1999)
Exp. Hematol.
, vol.27
, pp. 203-209
-
-
Matsuoka, M.1
Nishimoto, I.2
Asano, S.3
-
255
-
-
0032506347
-
IFNgamma inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21WAF1/CIP1
-
Kominsky, S., Johnson, H. M., Bryan, G., Tanabe, T., Hobeika, A. C., Subramaniam, P. S., Torres, B. (1998) IFNgamma inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21WAF1/CIP1. Oncogene 17, 2973-2979.
-
(1998)
Oncogene
, vol.17
, pp. 2973-2979
-
-
Kominsky, S.1
Johnson, H.M.2
Bryan, G.3
Tanabe, T.4
Hobeika, A.C.5
Subramaniam, P.S.6
Torres, B.7
-
256
-
-
0032518668
-
Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK)
-
Mandal, M., Bandyopadhyay, D., Goepfert, T. M., Kumar, R. (1998) Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK). Oncogene 16, 217-225.
-
(1998)
Oncogene
, vol.16
, pp. 217-225
-
-
Mandal, M.1
Bandyopadhyay, D.2
Goepfert, T.M.3
Kumar, R.4
-
257
-
-
0029832323
-
Gamma-interferon induces an irreversible growth arrest in mid-G1 in mammary epithelial cells which correlates with a block in hyperphosphorylation of retinoblastoma
-
Harvat, B. L., Jetten, A. M. (1996) Gamma-interferon induces an irreversible growth arrest in mid-G1 in mammary epithelial cells which correlates with a block in hyperphosphorylation of retinoblastoma. Cell Growth Differ. 7, 289-300.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 289-300
-
-
Harvat, B.L.1
Jetten, A.M.2
-
258
-
-
0030750887
-
Inhibition of E2F-4/DP-1-stimulated transcription by p202
-
Choubey, D., Gutterman, J. U. (1997) Inhibition of E2F-4/DP-1-stimulated transcription by p202. Oncogene 15, 291-301.
-
(1997)
Oncogene
, vol.15
, pp. 291-301
-
-
Choubey, D.1
Gutterman, J.U.2
-
259
-
-
0027408096
-
Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
-
Ayer, D. E., Kretzner, L., Eisenman, R. N. (1993) Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell 72, 211-222.
-
(1993)
Cell
, vol.72
, pp. 211-222
-
-
Ayer, D.E.1
Kretzner, L.2
Eisenman, R.N.3
-
260
-
-
0027431276
-
A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation
-
Ayer, D. E., Eisenman, R. N. (1993) A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. Genes Dev. 7, 2110-2119.
-
(1993)
Genes Dev.
, vol.7
, pp. 2110-2119
-
-
Ayer, D.E.1
Eisenman, R.N.2
-
261
-
-
0030906519
-
Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation
-
Cultraro, C. M., Bino, T., Segal, S. (1997) Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation. Mol. Cell. Biol. 17, 2353-2359.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2353-2359
-
-
Cultraro, C.M.1
Bino, T.2
Segal, S.3
-
262
-
-
0028938120
-
Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro
-
Vastrik, I., Kaipainen, A., Penttila, T. L., Lymboussakis, A., Alitalo, R., Parvinen, M., Alitalo, K. (1995) Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro. J. Cell Biol. 128, 1197-1208.
-
(1995)
J. Cell Biol.
, vol.128
, pp. 1197-1208
-
-
Vastrik, I.1
Kaipainen, A.2
Penttila, T.L.3
Lymboussakis, A.4
Alitalo, R.5
Parvinen, M.6
Alitalo, K.7
-
263
-
-
0033551389
-
Mysterious liaisons: The relationship between c-Myc and the cell cycle
-
Obaya, A. J., Mateyak, M. K., Sedivy, J. M. (1999) Mysterious liaisons: the relationship between c-Myc and the cell cycle. Oncogene 18, 2934-2941.
-
(1999)
Oncogene
, vol.18
, pp. 2934-2941
-
-
Obaya, A.J.1
Mateyak, M.K.2
Sedivy, J.M.3
-
264
-
-
0029078723
-
Deregulated c-myc expression overrides IFN gamma-induced macrophage growth arrest
-
Vairo, G., Vadiveloo, P. K., Royston, A. K., Rockman, S. P., Rock, C. O., Jackowski, S., Hamilton, J. A. (1995) Deregulated c-myc expression overrides IFN gamma-induced macrophage growth arrest. Oncogene 10, 1969-1976.
-
(1995)
Oncogene
, vol.10
, pp. 1969-1976
-
-
Vairo, G.1
Vadiveloo, P.K.2
Royston, A.K.3
Rockman, S.P.4
Rock, C.O.5
Jackowski, S.6
Hamilton, J.A.7
-
266
-
-
0030754555
-
IRF-1: The transcription factor linking the interferon response and oncogenesis
-
Taniguchi, T., Lamphier, M. S., Tanaka, N. (1997) IRF-1: the transcription factor linking the interferon response and oncogenesis. Biochim. Biophys. Acta 1333, M9-17.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
-
-
Taniguchi, T.1
Lamphier, M.S.2
Tanaka, N.3
-
267
-
-
0030769379
-
DNA damage-induced apoptosis and ice gene induction in mitogenically activated T lymphocytes require IRF-1
-
Tamura, T., Ishihara, M., Lamphier, M. S., Tanaka, N., Oishi, I., Aizawa, S., Matsuyama, T., Mak, T. W., Taki, S., Taniguchi, T. (1997) DNA damage-induced apoptosis and ice gene induction in mitogenically activated T lymphocytes require IRF-1. Leukemia 11, (Suppl. 3), 439-440.
-
(1997)
Leukemia
, vol.11
, Issue.SUPPL. 3
, pp. 439-440
-
-
Tamura, T.1
Ishihara, M.2
Lamphier, M.S.3
Tanaka, N.4
Oishi, I.5
Aizawa, S.6
Matsuyama, T.7
Mak, T.W.8
Taki, S.9
Taniguchi, T.10
-
268
-
-
0343990060
-
Caspases and caspase inhibitors
-
Villa, P., Kaufmann, S. H., Earnshaw, W. C. (1997) Caspases and caspase inhibitors. Trends Biochem. Sci. 22, 388-393.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 388-393
-
-
Villa, P.1
Kaufmann, S.H.2
Earnshaw, W.C.3
-
269
-
-
0030788405
-
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
-
Chin, Y. E., Kitagawa, M., Kuida, K., Flavell, R. A., Fu, X. Y. (1997) Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol. Cell. Biol. 17, 5328-5337.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5328-5337
-
-
Chin, Y.E.1
Kitagawa, M.2
Kuida, K.3
Flavell, R.A.4
Fu, X.Y.5
-
270
-
-
0029842883
-
Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection
-
Takizawa, T., Ohashi, K., Nakanishi, Y. (1996) Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection. J. Virol. 70, 8128-8132.
-
(1996)
J. Virol.
, vol.70
, pp. 8128-8132
-
-
Takizawa, T.1
Ohashi, K.2
Nakanishi, Y.3
-
271
-
-
0029981093
-
An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells
-
Yeung, M. C., Liu, J., Lau, A. S. (1996) An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells. Proc. Natl. Acad. Sci. USA 93, 12451-12455.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12451-12455
-
-
Yeung, M.C.1
Liu, J.2
Lau, A.S.3
-
272
-
-
0028290902
-
The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
-
Lee, S. B., Esteban, M. (1994) The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199, 491-496.
-
(1994)
Virology
, vol.199
, pp. 491-496
-
-
Lee, S.B.1
Esteban, M.2
-
273
-
-
0030664814
-
DAP kinase links the control of apoptosis to metastasis
-
Inbal, B., Cohen, O., Polak-Charcon, S., Kopolovic, J., Vadai, E., Eisenbach, L., Kimchi, A. (1997) DAP kinase links the control of apoptosis to metastasis. Nature 390, 180-184.
-
(1997)
Nature
, vol.390
, pp. 180-184
-
-
Inbal, B.1
Cohen, O.2
Polak-Charcon, S.3
Kopolovic, J.4
Vadai, E.5
Eisenbach, L.6
Kimchi, A.7
-
274
-
-
0028831202
-
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death
-
Deiss, L. P., Feinstein, E., Berissi, H., Cohen, O., Kimchi, A. (1995) Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 9, 15-30.
-
(1995)
Genes Dev.
, vol.9
, pp. 15-30
-
-
Deiss, L.P.1
Feinstein, E.2
Berissi, H.3
Cohen, O.4
Kimchi, A.5
-
275
-
-
0028783960
-
Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death
-
Kissil, J. L., Deiss, L. P., Bayewitch, M., Raveh, T., Khaspekov, G., Kimchi, A. (1995) Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. J. Biol. Chem. 270, 27932-27936.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27932-27936
-
-
Kissil, J.L.1
Deiss, L.P.2
Bayewitch, M.3
Raveh, T.4
Khaspekov, G.5
Kimchi, A.6
-
276
-
-
0031017473
-
DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death
-
Levy-Strumpf, N., Deiss, L. P., Berissi, H., Kimchi, A. (1997) DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death. Mol. Cell. Biol. 17, 1615-1625.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1615-1625
-
-
Levy-Strumpf, N.1
Deiss, L.P.2
Berissi, H.3
Kimchi, A.4
-
277
-
-
0029782494
-
Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
-
Deiss, L. P., Galinka, H., Berissi, H., Cohen, O., Kimchi, A. (1996) Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J. 15, 3861-3870.
-
(1996)
EMBO J.
, vol.15
, pp. 3861-3870
-
-
Deiss, L.P.1
Galinka, H.2
Berissi, H.3
Cohen, O.4
Kimchi, A.5
-
278
-
-
0032125574
-
IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: Requirement of STAT1 protein for up-regulation of Fas and FasL expression
-
Xu, X., Fu, X. Y., Plate, J., Chong, A. S. (1998) IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res. 58, 2832-2837.
-
(1998)
Cancer Res.
, vol.58
, pp. 2832-2837
-
-
Xu, X.1
Fu, X.Y.2
Plate, J.3
Chong, A.S.4
-
279
-
-
0842309451
-
Interferon-gamma up-regulates Fas expression and increases Fas-mediated apoptosis in tumor cell lines
-
Zheng, H., Luo, R. C., Zhang, L. S., Mai, G. F. (2002) Interferon-gamma up-regulates Fas expression and increases Fas-mediated apoptosis in tumor cell lines. Di Yi Jun Yi Da Xue Xue Bao 22, 1090-1092.
-
(2002)
Di Yi Jun Yi Da Xue Xue Bao
, vol.22
, pp. 1090-1092
-
-
Zheng, H.1
Luo, R.C.2
Zhang, L.S.3
Mai, G.F.4
-
280
-
-
0022651155
-
Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor
-
Tsujimoto, M., Yip, Y. K., Vilcek, J. (1986) Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor. J. Immunol. 136, 2441-2444.
-
(1986)
J. Immunol.
, vol.136
, pp. 2441-2444
-
-
Tsujimoto, M.1
Yip, Y.K.2
Vilcek, J.3
-
281
-
-
0030937832
-
Nitric oxide and macrophage function
-
MacMicking, J., Xie, Q. W., Nathan, C. (1997) Nitric oxide and macrophage function. Annu. Rev. Immunol. 15, 323-350.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 323-350
-
-
MacMicking, J.1
Xie, Q.W.2
Nathan, C.3
-
282
-
-
0030005411
-
The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic beta cells
-
Eizirik, D. L., Flodstrom, M., Karlsen, A. E., Welsh, N. (1996) The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells. Diabetologia 39, 875-890.
-
(1996)
Diabetologia
, vol.39
, pp. 875-890
-
-
Eizirik, D.L.1
Flodstrom, M.2
Karlsen, A.E.3
Welsh, N.4
-
283
-
-
0035919172
-
Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells
-
Kawahara, K., Gotoh, T., Oyadomari, S., Kajizono, M., Kuniyasu, A., Ohsawa, K., Imai, Y., Kohsaka, S., Nakayama, H., Mori, M. (2001) Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells. Brain Res. Mol. Brain Res. 90, 165-173.
-
(2001)
Brain Res. Mol. Brain Res.
, vol.90
, pp. 165-173
-
-
Kawahara, K.1
Gotoh, T.2
Oyadomari, S.3
Kajizono, M.4
Kuniyasu, A.5
Ohsawa, K.6
Imai, Y.7
Kohsaka, S.8
Nakayama, H.9
Mori, M.10
-
284
-
-
0028084722
-
Coinduction of nitric oxide synthase and argininosuccinate synthetase in a murine macrophage cell line. Implications for regulation of nitric oxide production
-
Nussler, A. K., Billiar, T. R., Liu, Z. Z., Morris Jr., S. M. (1994) Coinduction of nitric oxide synthase and argininosuccinate synthetase in a murine macrophage cell line. Implications for regulation of nitric oxide production. J. Biol. Chem. 269, 1257-1261.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1257-1261
-
-
Nussler, A.K.1
Billiar, T.R.2
Liu, Z.Z.3
Morris Jr., S.M.4
-
285
-
-
0027440763
-
Inducible nitric oxide synthase activity in hepatocytes is dependent on the coinduction of tetrahydrobiopterin synthesis
-
Di Silvio, M., Geller, D. A., Gross, S. S., Nussler, A., Freeswick, P., Simmons, R. L., Billiar, T. R. (1993) Inducible nitric oxide synthase activity in hepatocytes is dependent on the coinduction of tetrahydrobiopterin synthesis. Adv. Exp. Med. Biol. 338, 305-308.
-
(1993)
Adv. Exp. Med. Biol.
, vol.338
, pp. 305-308
-
-
Di Silvio, M.1
Geller, D.A.2
Gross, S.S.3
Nussler, A.4
Freeswick, P.5
Simmons, R.L.6
Billiar, T.R.7
-
286
-
-
0027441142
-
Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme
-
Baek, K. J., Thiel, B. A., Lucas, S., Stuehr, D. J. (1993) Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. J. Biol. Chem. 268, 21120-21129.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21120-21129
-
-
Baek, K.J.1
Thiel, B.A.2
Lucas, S.3
Stuehr, D.J.4
-
287
-
-
0025245629
-
Molecular basis of interferon-gamma and lipopolysaccharide enhancement of phagocyte respiratory burst capability. Studies on the gene expression of several NADPH oxidase components
-
Cassatella, M. A., Bazzoni, F., Flynn, R. M., Dusi, S., Trinchieri, G., Rossi, F. (1990) Molecular basis of interferon-gamma and lipopolysaccharide enhancement of phagocyte respiratory burst capability. Studies on the gene expression of several NADPH oxidase components. J. Biol. Chem. 265, 20241-20246.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20241-20246
-
-
Cassatella, M.A.1
Bazzoni, F.2
Flynn, R.M.3
Dusi, S.4
Trinchieri, G.5
Rossi, F.6
-
288
-
-
0242455509
-
Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma
-
Newburger, P. E., Ezekowitz, R. A., Whitney, C., Wright, J., Orkin, S. H. (1988) Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma. Proc. Natl. Acad. Sci. USA 85, 5215-5219.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5215-5219
-
-
Newburger, P.E.1
Ezekowitz, R.A.2
Whitney, C.3
Wright, J.4
Orkin, S.H.5
-
289
-
-
0026651071
-
Induction of expression of genes encoding components of the respiratory burst oxidase during differentiation of human myeloid cell lines induced by tumor necrosis factor and gamma-interferon
-
Gupta, J. W., Kubin, M., Hartman, L., Cassatella, M., Trinchieri, G. (1992) Induction of expression of genes encoding components of the respiratory burst oxidase during differentiation of human myeloid cell lines induced by tumor necrosis factor and gamma-interferon. Cancer Res. 52, 2530-2537.
-
(1992)
Cancer Res.
, vol.52
, pp. 2530-2537
-
-
Gupta, J.W.1
Kubin, M.2
Hartman, L.3
Cassatella, M.4
Trinchieri, G.5
-
290
-
-
0029054722
-
Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages
-
Govoni, G., Vidal, S., Cellier, M., Lepage, P., Malo, D., Gros, P. (1995) Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages. Genomics 27, 9-19.
-
(1995)
Genomics
, vol.27
, pp. 9-19
-
-
Govoni, G.1
Vidal, S.2
Cellier, M.3
Lepage, P.4
Malo, D.5
Gros, P.6
-
291
-
-
0025060402
-
The effect of cytokines on the expression and function of Fc receptors for IgG on human myeloid cells
-
Erbe, D. V., Collins, J. E., Shen, L., Graziano, R. F., Fanger, M. W. (1990) The effect of cytokines on the expression and function of Fc receptors for IgG on human myeloid cells. Mol. Immunol. 27, 57-67.
-
(1990)
Mol. Immunol.
, vol.27
, pp. 57-67
-
-
Erbe, D.V.1
Collins, J.E.2
Shen, L.3
Graziano, R.F.4
Fanger, M.W.5
-
292
-
-
0022371237
-
Gamma-interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genes
-
Strunk, R. C., Cole, F. S., Perlmutter, D. H., Colten, H. R. (1985) Gamma-interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genes. J. Biol. Chem. 260, 15280-15285.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 15280-15285
-
-
Strunk, R.C.1
Cole, F.S.2
Perlmutter, D.H.3
Colten, H.R.4
-
293
-
-
0027166714
-
Synthesis and regulation of complement components by human monocytes/macrophages and by acute monocytic leukemia
-
Vincent, F., de la Salle, H., Bohbot, A., Bergerat, J. P., Hauptmann, G., Oberling, F. (1993) Synthesis and regulation of complement components by human monocytes/macrophages and by acute monocytic leukemia. DNA Cell Biol. 12, 415-423.
-
(1993)
DNA Cell Biol.
, vol.12
, pp. 415-423
-
-
Vincent, F.1
De La Salle, H.2
Bohbot, A.3
Bergerat, J.P.4
Hauptmann, G.5
Oberling, F.6
-
294
-
-
0022509870
-
Regulation of complement protein biosynthesis in mononuclear phagocytes
-
Colten, H. R., Strunk, R. C., Perlmutter, D. H., Cole, F. S. (1986) Regulation of complement protein biosynthesis in mononuclear phagocytes. Ciba Found. Symp. 118, 141-154.
-
(1986)
Ciba Found. Symp.
, vol.118
, pp. 141-154
-
-
Colten, H.R.1
Strunk, R.C.2
Perlmutter, D.H.3
Cole, F.S.4
-
295
-
-
0029916602
-
Complement receptor type 3 mediates phagocytosis and killing of Listeria monocytogenes by a TNF-alpha- and IFN-gamma-stimulated macrophage precursor hybrid
-
Drevets, D. A., Leenen, P. J., Camphell, P. A. (1996) Complement receptor type 3 mediates phagocytosis and killing of Listeria monocytogenes by a TNF-alpha- and IFN-gamma-stimulated macrophage precursor hybrid. Cell. Immunol. 169, 1-6.
-
(1996)
Cell. Immunol.
, vol.169
, pp. 1-6
-
-
Drevets, D.A.1
Leenen, P.J.2
Camphell, P.A.3
-
296
-
-
0028176574
-
IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774
-
Yoshida, A., Koide, Y., Uchijima, M., Yoshida, T. O. (1994) IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774. Biochem. Biophys. Res. Commun. 198, 857-861.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.198
, pp. 857-861
-
-
Yoshida, A.1
Koide, Y.2
Uchijima, M.3
Yoshida, T.O.4
-
297
-
-
0028316546
-
Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1 beta production in human myeloid leukemia cell lines and peripheral blood mononuclear cells
-
Kubin, M., Chow, J. M., Trinchieri, G. (1994) Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1 beta production in human myeloid leukemia cell lines and peripheral blood mononuclear cells. Blood 83, 1847-1855.
-
(1994)
Blood
, vol.83
, pp. 1847-1855
-
-
Kubin, M.1
Chow, J.M.2
Trinchieri, G.3
-
298
-
-
0027315862
-
Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells
-
Taub, D. D., Lloyd, A. R., Conlon, K., Wang, J. M., Ortaldo, J. R., Harada, A., Matsushima, K., Kelvin, D. J., Oppenheim, J. J. (1993) Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J. Exp. Med. 177, 1809-1814.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1809-1814
-
-
Taub, D.D.1
Lloyd, A.R.2
Conlon, K.3
Wang, J.M.4
Ortaldo, J.R.5
Harada, A.6
Matsushima, K.7
Kelvin, D.J.8
Oppenheim, J.J.9
-
299
-
-
0025354165
-
Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE
-
Rollins, B. J., Yoshimura, T., Leonard, E. J., Pober, J. S. (1990) Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE. Am. J. Pathol. 136, 1229-1233.
-
(1990)
Am. J. Pathol.
, vol.136
, pp. 1229-1233
-
-
Rollins, B.J.1
Yoshimura, T.2
Leonard, E.J.3
Pober, J.S.4
-
300
-
-
0028832279
-
Human Mig chemokine: Biochemical and functional characterization
-
Liao, F., Rabin, R. L., Yannelli, J. R., Koniaris, L. G., Vanguri, P., Farber, J. M. (1995) Human Mig chemokine: biochemical and functional characterization. J. Exp. Med. 182, 1301-1314.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1301-1314
-
-
Liao, F.1
Rabin, R.L.2
Yannelli, J.R.3
Koniaris, L.G.4
Vanguri, P.5
Farber, J.M.6
-
301
-
-
0027157494
-
Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1 alpha and MIP-1 beta
-
Taub, D. D., Conlon, K., Lloyd, A. R., Oppenheim, J. J., Kelvin, D. J. (1993) Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1 alpha and MIP-1 beta. Science 260, 355-358.
-
(1993)
Science
, vol.260
, pp. 355-358
-
-
Taub, D.D.1
Conlon, K.2
Lloyd, A.R.3
Oppenheim, J.J.4
Kelvin, D.J.5
-
302
-
-
0034918334
-
RANTES: A versatile and controversial chemokine
-
Appay, V., Rowland-Jones, S. L. (2001) RANTES: a versatile and controversial chemokine. Trends Immunol. 22, 83-87.
-
(2001)
Trends Immunol.
, vol.22
, pp. 83-87
-
-
Appay, V.1
Rowland-Jones, S.L.2
-
303
-
-
0028073850
-
Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1
-
Hou, J., Baichwal, V., Cao, Z. (1994) Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. USA 91, 11641-11645.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11641-11645
-
-
Hou, J.1
Baichwal, V.2
Cao, Z.3
-
304
-
-
0032498798
-
Interferon regulatory factor-2 is a transcriptional activator in muscle where it regulates expression of vascular cell adhesion molecule-1
-
Jesse, T. L., LaChance, R., Iademarco, M. F., Dean, D. C. (1998) Interferon regulatory factor-2 is a transcriptional activator in muscle where it regulates expression of vascular cell adhesion molecule-1. J. Cell Biol. 140, 1265-1276.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 1265-1276
-
-
Jesse, T.L.1
LaChance, R.2
Iademarco, M.F.3
Dean, D.C.4
-
305
-
-
0029994319
-
Interferon-gamma: Biology and role in pathogenesis
-
Billiau, A. (1996) Interferon-gamma: biology and role in pathogenesis. Adv. Immunol. 62, 61-130.
-
(1996)
Adv. Immunol.
, vol.62
, pp. 61-130
-
-
Billiau, A.1
-
306
-
-
0029920469
-
Antigen processing and presentation by the class I major histocompatibility complex
-
York, I. A., Rock, K. L. (1996) Antigen processing and presentation by the class I major histocompatibility complex. Annu. Rev. Immunol. 14, 369-396.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 369-396
-
-
York, I.A.1
Rock, K.L.2
-
307
-
-
0028817950
-
Dependence of peptide binding by MHC class I molecules on their interaction with TAP
-
Grandea III, A. G., Androlewicz, M. J., Athwal, R. S., Geraghty, D. E., Spies, T. (1995) Dependence of peptide binding by MHC class I molecules on their interaction with TAP. Science 270, 105-108.
-
(1995)
Science
, vol.270
, pp. 105-108
-
-
Grandea III, A.G.1
Androlewicz, M.J.2
Athwal, R.S.3
Geraghty, D.E.4
Spies, T.5
-
308
-
-
0028060636
-
The endoplasmic reticular heat shock protein gp96 is transcriptionally upregulated in interferon-treated cells
-
Anderson, S. L., Shen, T., Lou, J., Xing, L., Blachere, N. E., Srivastava, P. K., Rubin, B. Y. (1994) The endoplasmic reticular heat shock protein gp96 is transcriptionally upregulated in interferon-treated cells. J. Exp. Med. 180, 1565-1569.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1565-1569
-
-
Anderson, S.L.1
Shen, T.2
Lou, J.3
Xing, L.4
Blachere, N.E.5
Srivastava, P.K.6
Rubin, B.Y.7
-
309
-
-
0028979675
-
A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
-
Suto, R., Srivastava, P. K. (1995) A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides. Science 269, 1585-1588.
-
(1995)
Science
, vol.269
, pp. 1585-1588
-
-
Suto, R.1
Srivastava, P.K.2
-
310
-
-
0029968925
-
Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression
-
Chang, C. H., Guerder, S., Hong, S. C., van Ewijk, W., Flavell, R. A. (1996) Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression. Immunity 4, 167-178.
-
(1996)
Immunity
, vol.4
, pp. 167-178
-
-
Chang, C.H.1
Guerder, S.2
Hong, S.C.3
Van Ewijk, W.4
Flavell, R.A.5
-
311
-
-
0024518769
-
Combined immunodeficiency with defective expression in MHC class II genes
-
Griscelli, C., Lisowska-Grospierre, B., Mach, B. (1989) Combined immunodeficiency with defective expression in MHC class II genes. Immunodeficiency. Rev. 1, 135-153.
-
(1989)
Immunodeficiency. Rev.
, vol.1
, pp. 135-153
-
-
Griscelli, C.1
Lisowska-Grospierre, B.2
Mach, B.3
-
312
-
-
0028041568
-
Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes
-
Chang, C. H., Fontes, J. D., Peterlin, M., Flavell, R. A. (1994) Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J. Exp. Med. 180, 1367-1374.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1367-1374
-
-
Chang, C.H.1
Fontes, J.D.2
Peterlin, M.3
Flavell, R.A.4
-
313
-
-
0034511922
-
Lessons from the bare lymphocyte syndrome: Molecular mechanisms regulating MHC class II expression
-
Waldburger, J. M., Masternak, K., Muhlethaler-Mottet, A., Villard, J., Peretti, M., Landmann, S., Reith, W. (2000) Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression. Immunol. Rev. 178, 148-165.
-
(2000)
Immunol. Rev.
, vol.178
, pp. 148-165
-
-
Waldburger, J.M.1
Masternak, K.2
Muhlethaler-Mottet, A.3
Villard, J.4
Peretti, M.5
Landmann, S.6
Reith, W.7
-
314
-
-
0031050035
-
Regulation of transcription of MHC class II genes
-
Boss, J. M. (1997) Regulation of transcription of MHC class II genes. Curr. Opin. Immunol. 9, 107-113.
-
(1997)
Curr. Opin. Immunol.
, vol.9
, pp. 107-113
-
-
Boss, J.M.1
-
315
-
-
13344259977
-
Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells
-
Heufler, C., Koch, F., Stanzl, U., Topar, G., Wysocka, M., Trinchieri, G., Enk, A., Steinman, R. M., Romani, N., Schuler, G. (1996) Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells. Eur. J. Immunol. 26, 659-668.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 659-668
-
-
Heufler, C.1
Koch, F.2
Stanzl, U.3
Topar, G.4
Wysocka, M.5
Trinchieri, G.6
Enk, A.7
Steinman, R.M.8
Romani, N.9
Schuler, G.10
-
316
-
-
0028878655
-
Interleukin-12 gene expression after viral infection in the mouse
-
Coutelier, J. P., Van Broeck, L. Wolf, S. F. (1995) Interleukin-12 gene expression after viral infection in the mouse. J. Virol. 69, 1955-1958.
-
(1995)
J. Virol.
, vol.69
, pp. 1955-1958
-
-
Coutelier, J.P.1
Van Broeck, L.2
Wolf, S.F.3
-
317
-
-
0033564304
-
Human polymorphonuclear leukocytes produce IL-12, TNF-alpha, and the chemokines macrophage-inflammatory protein-1 alpha and -1 beta in response to Toxoplasma gondii antigens
-
Bliss, S. K., Marshall, A. J., Zhang, Y., Denkers, E. Y. (1999) Human polymorphonuclear leukocytes produce IL-12, TNF-alpha, and the chemokines macrophage-inflammatory protein-1 alpha and -1 beta in response to Toxoplasma gondii antigens. J. Immunol. 162, 7369-7375.
-
(1999)
J. Immunol.
, vol.162
, pp. 7369-7375
-
-
Bliss, S.K.1
Marshall, A.J.2
Zhang, Y.3
Denkers, E.Y.4
-
318
-
-
0028906439
-
Interleukin-12 production by human polymorphonuclear leukocytes
-
Cassatella, M. A., Meda, L., Gasperini, S., D'Andrea, A., Ma, X., Trinchieri, G. (1995) Interleukin-12 production by human polymorphonuclear leukocytes. Eur. J. Immunol. 25, 1-5.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1-5
-
-
Cassatella, M.A.1
Meda, L.2
Gasperini, S.3
D'Andrea, A.4
Ma, X.5
Trinchieri, G.6
-
319
-
-
0029014952
-
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells
-
Macatonia, S. E., Hosken, N. A., Litton, M., Vieira, P., Hsieh, C. S., Culpepper, J. A., Wysocka, M., Trinchieri, G., Murphy, K. M., O'Garra, A. (1995) Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J. Immunol. 154, 5071-5079.
-
(1995)
J. Immunol.
, vol.154
, pp. 5071-5079
-
-
Macatonia, S.E.1
Hosken, N.A.2
Litton, M.3
Vieira, P.4
Hsieh, C.S.5
Culpepper, J.A.6
Wysocka, M.7
Trinchieri, G.8
Murphy, K.M.9
O'Garra, A.10
-
320
-
-
0029788387
-
Cytokine transcriptional events during helper T cell subset differentiation
-
Lederer, J. A., Perez, V. L., DesRoches, L., Kim, S. M., Abbas, A. K., Lichtman, A. H. (1996) Cytokine transcriptional events during helper T cell subset differentiation. J. Exp. Med. 184, 397-406.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 397-406
-
-
Lederer, J.A.1
Perez, V.L.2
DesRoches, L.3
Kim, S.M.4
Abbas, A.K.5
Lichtman, A.H.6
-
321
-
-
0028970060
-
Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
Trinchieri, G. (1995) Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13, 251-276.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251-276
-
-
Trinchieri, G.1
-
322
-
-
0032150409
-
Cytokine measurement at a single-cell level to analyze human Th1 and Th2 cells
-
Morinobu, A., Kumagai, S. (1998) Cytokine measurement at a single-cell level to analyze human Th1 and Th2 cells. Rinsho Byori 46, 908-914.
-
(1998)
Rinsho Byori
, vol.46
, pp. 908-914
-
-
Morinobu, A.1
Kumagai, S.2
-
323
-
-
0024460107
-
IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma
-
Lehn, M., Weiser, W. Y., Engelhorn, S., Gillis, S., Remold, H. G. (1989) IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma. J. Immunol. 143, 3020-3024.
-
(1989)
J. Immunol.
, vol.143
, pp. 3020-3024
-
-
Lehn, M.1
Weiser, W.Y.2
Engelhorn, S.3
Gillis, S.4
Remold, H.G.5
-
324
-
-
0026042191
-
A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages
-
Liew, F. Y., Li, Y., Severn, A., Millott, S., Schmidt, J., Salter, M., Moncada, S. (1991) A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages. Eur. J. Immunol. 21, 2489-2494.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2489-2494
-
-
Liew, F.Y.1
Li, Y.2
Severn, A.3
Millott, S.4
Schmidt, J.5
Salter, M.6
Moncada, S.7
-
325
-
-
0023923990
-
Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma
-
Rousset, F., Malefijt, R. W., Slierendregt, B., Aubry, J. P., Bonnefoy, J. Y., Defrance, T., Banchereau, J., de Vries, J. E. (1988) Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma. J. Immunol. 140, 2625-2632.
-
(1988)
J. Immunol.
, vol.140
, pp. 2625-2632
-
-
Rousset, F.1
Malefijt, R.W.2
Slierendregt, B.3
Aubry, J.P.4
Bonnefoy, J.Y.5
Defrance, T.6
Banchereau, J.7
De Vries, J.E.8
-
326
-
-
0036467492
-
The interferon-alpha/beta system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors
-
Taniguchi, T., Takaoka, A. (2002) The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr. Opin. Immunol. 14, 111-116.
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 111-116
-
-
Taniguchi, T.1
Takaoka, A.2
-
327
-
-
0032493299
-
Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice
-
Lu, B., Ebensperger, C., Dembic, Z., Wang, Y., Kvatyuk, M., Lu, T., Coffman, R. L., Pestka, S., Rothman, P. B. (1998) Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice. Proc. Natl. Acad. Sci. USA 95, 8233-8238.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8233-8238
-
-
Lu, B.1
Ebensperger, C.2
Dembic, Z.3
Wang, Y.4
Kvatyuk, M.5
Lu, T.6
Coffman, R.L.7
Pestka, S.8
Rothman, P.B.9
-
328
-
-
0032976229
-
Role for gamma interferon in control of herpes simplex virus type 1 reactivation
-
Cantin, E., Tanamachi, B., Openshaw, H. (1999) Role for gamma interferon in control of herpes simplex virus type 1 reactivation. J. Virol. 73, 3418-3423.
-
(1999)
J. Virol.
, vol.73
, pp. 3418-3423
-
-
Cantin, E.1
Tanamachi, B.2
Openshaw, H.3
-
329
-
-
0029990084
-
Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q-associated leukemias
-
Beretta, L., Gabbay, M., Berger, R., Hanash, S. M., Sonenberg, N. (1996) Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q-associated leukemias. Oncogene 12, 1593-1596.
-
(1996)
Oncogene
, vol.12
, pp. 1593-1596
-
-
Beretta, L.1
Gabbay, M.2
Berger, R.3
Hanash, S.M.4
Sonenberg, N.5
-
330
-
-
0023180020
-
The double-stranded RNA-dependent protein kinase is also activated by heparin
-
Hovanessian, A. G., Galabru, J. (1987) The double-stranded RNA-dependent protein kinase is also activated by heparin. Eur. J. Biochem. 167, 467-473.
-
(1987)
Eur. J. Biochem.
, vol.167
, pp. 467-473
-
-
Hovanessian, A.G.1
Galabru, J.2
-
331
-
-
0033795196
-
Interferons: Cell signalling, immune modulation, antiviral response and virus countermeasures
-
Goodbourn, S., Didcock, L., Randall, R. E. (2000) Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures. J. Gen. Virol. 81, 2341-2364.
-
(2000)
J. Gen. Virol.
, vol.81
, pp. 2341-2364
-
-
Goodbourn, S.1
Didcock, L.2
Randall, R.E.3
-
332
-
-
0027308224
-
The interferon-induced double-stranded RNA-activated human p68 protein kinase potently inhibits protein synthesis in cultured cells
-
Lee, S. B., Melkova, Z., Yan, W., Williams, B. R., Hovanessian, A. G., Esteban, M. (1993) The interferon-induced double-stranded RNA-activated human p68 protein kinase potently inhibits protein synthesis in cultured cells. Virology 192, 380-385.
-
(1993)
Virology
, vol.192
, pp. 380-385
-
-
Lee, S.B.1
Melkova, Z.2
Yan, W.3
Williams, B.R.4
Hovanessian, A.G.5
Esteban, M.6
-
333
-
-
0033257795
-
JNK2 and IKKbeta are required for activating the innate response to viral infection
-
Chu, W. M., Ostertag, D., Li, Z. W., Chang, L., Chen, Y., Hu, Y., Williams, B., Perrault, J., Karin, M. (1999) JNK2 and IKKbeta are required for activating the innate response to viral infection. Immunity 11, 721-731.
-
(1999)
Immunity
, vol.11
, pp. 721-731
-
-
Chu, W.M.1
Ostertag, D.2
Li, Z.W.3
Chang, L.4
Chen, Y.5
Hu, Y.6
Williams, B.7
Perrault, J.8
Karin, M.9
-
334
-
-
0033526512
-
Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways
-
Zhou, A., Paranjape, J. M., Der, S. D., Williams, B. R., Silverman, R. H. (1999) Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways. Virology 258, 435-440.
-
(1999)
Virology
, vol.258
, pp. 435-440
-
-
Zhou, A.1
Paranjape, J.M.2
Der, S.D.3
Williams, B.R.4
Silverman, R.H.5
-
335
-
-
0035910758
-
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
-
Presti, R. M., Popkin, D. L., Connick, M., Paetzold, S., Virgin IV, H. W. (2001) Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages. J. Exp. Med. 193, 483-496.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 483-496
-
-
Presti, R.M.1
Popkin, D.L.2
Connick, M.3
Paetzold, S.4
Virgin IV, H.W.5
-
336
-
-
0035710839
-
Molecular mechanisms involved in macrophage survival, proliferation, activation or apoptosis
-
Xaus, J., Comalada, M., Valledor, A. F., Cardo, M., Herrero, C., Soler, C., Lloberas, J., Celada, A. (2001) Molecular mechanisms involved in macrophage survival, proliferation, activation or apoptosis. Immunobiology 204, 543-550.
-
(2001)
Immunobiology
, vol.204
, pp. 543-550
-
-
Xaus, J.1
Comalada, M.2
Valledor, A.F.3
Cardo, M.4
Herrero, C.5
Soler, C.6
Lloberas, J.7
Celada, A.8
-
337
-
-
0025871906
-
Interactions among granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and IFN-gamma lead to enhanced proliferation of murine macrophage progenitor cells
-
Breen, F. N., Hume, D. A., Weidemann, M. J. (1991) Interactions among granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and IFN-gamma lead to enhanced proliferation of murine macrophage progenitor cells. J. Immunol. 147, 1542-1547.
-
(1991)
J. Immunol.
, vol.147
, pp. 1542-1547
-
-
Breen, F.N.1
Hume, D.A.2
Weidemann, M.J.3
-
338
-
-
0018098799
-
Interferon affects both G1 and S+G2 in cells stimulated from quiescence to growth
-
Balkwill, F., Taylor-Papadimitriou, J. (1978) Interferon affects both G1 and S+G2 in cells stimulated from quiescence to growth. Nature 274, 798-800.
-
(1978)
Nature
, vol.274
, pp. 798-800
-
-
Balkwill, F.1
Taylor-Papadimitriou, J.2
-
339
-
-
0021275747
-
Interferon-induced cell cycle changes in human hematopoietic cell lines and fresh leukemic cells
-
Roos, G., Leanderson, T., Lundgren, E. (1984) Interferon-induced cell cycle changes in human hematopoietic cell lines and fresh leukemic cells. Cancer Res. 44, 2358-2362.
-
(1984)
Cancer Res.
, vol.44
, pp. 2358-2362
-
-
Roos, G.1
Leanderson, T.2
Lundgren, E.3
-
340
-
-
0019435294
-
Block of glioma cell line in S by interferon
-
Lundblad, D., Lundgren, E. (1981) Block of glioma cell line in S by interferon. Int. J. Cancer 27, 749-754.
-
(1981)
Int. J. Cancer
, vol.27
, pp. 749-754
-
-
Lundblad, D.1
Lundgren, E.2
-
341
-
-
0029997033
-
Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest
-
Tiefenbrun, N., Melamed, D., Levy, N., Resnitzky, D., Hoffman, I., Reed, S. I., Kimchi, A. (1996) Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. Mol. Cell. Biol. 16, 3934-3944.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3934-3944
-
-
Tiefenbrun, N.1
Melamed, D.2
Levy, N.3
Resnitzky, D.4
Hoffman, I.5
Reed, S.I.6
Kimchi, A.7
-
342
-
-
0031029580
-
Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-alpha in hematopoietic cell lines
-
Sangfelt, O., Erickson, S., Einhorn, S., Grander, D. (1997) Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-alpha in hematopoietic cell lines. Oncogene 14, 415-423.
-
(1997)
Oncogene
, vol.14
, pp. 415-423
-
-
Sangfelt, O.1
Erickson, S.2
Einhorn, S.3
Grander, D.4
-
343
-
-
0030609969
-
IFNalpha induces the expression of the cyclin-dependent kinase inhibitor p21 in human prostate cancer cells
-
Hobeika, A. C., Subramaniam, P. S., Johnson, H. M. (1997) IFNalpha induces the expression of the cyclin-dependent kinase inhibitor p21 in human prostate cancer cells. Oncogene 14, 1165-1170.
-
(1997)
Oncogene
, vol.14
, pp. 1165-1170
-
-
Hobeika, A.C.1
Subramaniam, P.S.2
Johnson, H.M.3
-
344
-
-
0029923780
-
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
-
Chin, Y. E., Kitagawa, M., Su, W. C., You, Z. H., Iwamoto, Y., Fu, X. Y. (1996) Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272, 719-722.
-
(1996)
Science
, vol.272
, pp. 719-722
-
-
Chin, Y.E.1
Kitagawa, M.2
Su, W.C.3
You, Z.H.4
Iwamoto, Y.5
Fu, X.Y.6
-
345
-
-
0036007314
-
Interferon-gamma inhibits hepatocyte growth factor-stimulated cell proliferation of human bronchial epithelial cells: Upregulation of p27(kip1) cyclin-dependent kinase inhibitor
-
Takami, K., Takuwa, N., Okazaki, H., Kohayashi, M., Ohtoshi, T., Kawasaki, S., Dohi, M., Yamamoto, K., Nakamura, T., Tanaka, M., Nakahara, K., Takuwa, Y., Takizawa, H. (2002) Interferon-gamma inhibits hepatocyte growth factor-stimulated cell proliferation of human bronchial epithelial cells: upregulation of p27(kip1) cyclin-dependent kinase inhibitor. Am. J. Respir. Cell Mol. Biol. 26, 231-238.
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.26
, pp. 231-238
-
-
Takami, K.1
Takuwa, N.2
Okazaki, H.3
Kohayashi, M.4
Ohtoshi, T.5
Kawasaki, S.6
Dohi, M.7
Yamamoto, K.8
Nakamura, T.9
Tanaka, M.10
Nakahara, K.11
Takuwa, Y.12
Takizawa, H.13
-
346
-
-
0033555782
-
Gamma interferon induces expression of Mad1 gene in macrophage, which inhibits colony-stimulating factor-1-dependent mitogenesis
-
Dey, A., Kim, L., Li, W. (1999) Gamma interferon induces expression of Mad1 gene in macrophage, which inhibits colony-stimulating factor-1-dependent mitogenesis. J. Cell. Biochem. 72, 232-241.
-
(1999)
J. Cell. Biochem.
, vol.72
, pp. 232-241
-
-
Dey, A.1
Kim, L.2
Li, W.3
-
347
-
-
0032078217
-
Caspases: Key mediators of apoptosis
-
Thornberry, N. A. (1998) Caspases: key mediators of apoptosis. Chem. Biol. 5, R97-103.
-
(1998)
Chem. Biol.
, vol.5
-
-
Thornberry, N.A.1
-
348
-
-
0030240383
-
Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor
-
Novelli, F., Bernabei, P., Ozmen, L., Rigamonti, L., Allione, A., Pestka, S., Garotta, G., Forni, G. (1996) Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor. J. Immunol. 157, 1935-1943.
-
(1996)
J. Immunol.
, vol.157
, pp. 1935-1943
-
-
Novelli, F.1
Bernabei, P.2
Ozmen, L.3
Rigamonti, L.4
Allione, A.5
Pestka, S.6
Garotta, G.7
Forni, G.8
-
349
-
-
0035066748
-
Regulation of interferon-gamma receptor (INF-gammaR) chains: A peculiar way to rule the life and death of human lymphocytes
-
Bernabei, P., Allione, A., Rigamonti, L., Bosticardo, M., Losana, G., Borghi, I., Forni, G., Novelli, F. (2001) Regulation of interferon-gamma receptor (INF-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes. Eur. Cytokine Netw. 12, 6-14.
-
(2001)
Eur. Cytokine Netw.
, vol.12
, pp. 6-14
-
-
Bernabei, P.1
Allione, A.2
Rigamonti, L.3
Bosticardo, M.4
Losana, G.5
Borghi, I.6
Forni, G.7
Novelli, F.8
-
350
-
-
0029005805
-
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis
-
Los, M., Van de Craen, M., Penning, L. C., Schenk, H., Westendorp, M., Baeuerle, P. A., Droge, W., Krammer, P. H., Fiers, W., Schulze-Osthoff, K. (1995) Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375, 81-83.
-
(1995)
Nature
, vol.375
, pp. 81-83
-
-
Los, M.1
Van De Craen, M.2
Penning, L.C.3
Schenk, H.4
Westendorp, M.5
Baeuerle, P.A.6
Droge, W.7
Krammer, P.H.8
Fiers, W.9
Schulze-Osthoff, K.10
-
351
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
-
Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A., Yuan, J. (1993) Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75, 653-660.
-
(1993)
Cell
, vol.75
, pp. 653-660
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
Hartwieg, E.A.4
Yuan, J.5
-
352
-
-
0033776461
-
Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses
-
Mathiak, G., Grass, G., Herzmann, T., Luebke, T., Zetina, C. C., Boehm. S. A., Bohlen, H., Neville, L. F., Hoelscher, A. H. (2000) Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses. Br. J. Pharmacol. 131, 383-386.
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 383-386
-
-
Mathiak, G.1
Grass, G.2
Herzmann, T.3
Luebke, T.4
Zetina, C.C.5
Boehm, S.A.6
Bohlen, H.7
Neville, L.F.8
Hoelscher, A.H.9
-
353
-
-
0032909752
-
Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1)
-
Fantuzzi, G., Dinarello, C. A. (1999) Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J. Clin. Immunol. 19, 1-11.
-
(1999)
J. Clin. Immunol.
, vol.19
, pp. 1-11
-
-
Fantuzzi, G.1
Dinarello, C.A.2
-
354
-
-
0842266201
-
Generation of reactive oxygen species by phagocytes
-
(R. van Furth, ed.), Dordrecht, The Netherlands, Kluwer Academic
-
Roos, D., Botscher, B. G. J., de Boer, M. (1992) Generation of reactive oxygen species by phagocytes. In Mononuclear Phagocytes: Biology, of Monocytes and Macrophages (R. van Furth, ed.), Dordrecht, The Netherlands, Kluwer Academic, 243-253.
-
(1992)
Mononuclear Phagocytes: Biology, of Monocytes and Macrophages
, pp. 243-253
-
-
Roos, D.1
Botscher, B.G.J.2
De Boer, M.3
-
355
-
-
0002487841
-
Antimicrobial mechanisms of macrophages
-
(R. van Furth, ed.), Dordrecht, The Netherlands, Kluwer Academic
-
Nathan, C. F., Gabay, J. (1992) Antimicrobial mechanisms of macrophages. In Mononuclear Phagocytes: Biology of Monocytes and Macrophages (R. van Furth, ed.), Dordrecht, The Netherlands, Kluwer Academic, 259-267.
-
(1992)
Mononuclear Phagocytes: Biology of Monocytes and Macrophages
, pp. 259-267
-
-
Nathan, C.F.1
Gabay, J.2
-
356
-
-
0032984248
-
Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase
-
Shiloh, M. U., MacMicking, J. D., Nicholson, S., Brause, J. E., Potter, S., Marino, M., Fang, F., Dinauer, M., Nathan, C. (1999) Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. Immunity 10, 29-38.
-
(1999)
Immunity
, vol.10
, pp. 29-38
-
-
Shiloh, M.U.1
MacMicking, J.D.2
Nicholson, S.3
Brause, J.E.4
Potter, S.5
Marino, M.6
Fang, F.7
Dinauer, M.8
Nathan, C.9
-
357
-
-
0027488067
-
Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase
-
Karupiah, G., Xie, Q. W., Buller, R. M., Nathan, C., Duarte, C., MacMicking, J. D. (1993) Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase. Science 261, 1445-1448.
-
(1993)
Science
, vol.261
, pp. 1445-1448
-
-
Karupiah, G.1
Xie, Q.W.2
Buller, R.M.3
Nathan, C.4
Duarte, C.5
MacMicking, J.D.6
-
358
-
-
0025791009
-
Cytokine-induced synthesis of nitrogen oxides in macrophages: A protective host response to Leishmania and other intracellular pathogens
-
Green, S. J., Nacy, C. A., Meltzer, M. S. (1991) Cytokine-induced synthesis of nitrogen oxides in macrophages: a protective host response to Leishmania and other intracellular pathogens. J. Leukoc. Biol. 50, 93-103.
-
(1991)
J. Leukoc. Biol.
, vol.50
, pp. 93-103
-
-
Green, S.J.1
Nacy, C.A.2
Meltzer, M.S.3
-
359
-
-
0025648446
-
Leishmania major amastigotes initiate the L-ariginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha
-
Green, S. J., Crawford, R. M., Hockmeyer, J. T., Meltzer, M. S., Nacy, C. A. (1990) Leishmania major amastigotes initiate the L-ariginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha. J. Immunol. 145, 4290-4297.
-
(1990)
J. Immunol.
, vol.145
, pp. 4290-4297
-
-
Green, S.J.1
Crawford, R.M.2
Hockmeyer, J.T.3
Meltzer, M.S.4
Nacy, C.A.5
-
360
-
-
0025864926
-
Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: Killing effector mechanism depends on the generation of reactive nitrogen intermediates
-
Denis, M. (1991) Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: killing effector mechanism depends on the generation of reactive nitrogen intermediates. J. Leukoc. Biol. 49, 380-387.
-
(1991)
J. Leukoc. Biol.
, vol.49
, pp. 380-387
-
-
Denis, M.1
-
361
-
-
0029035476
-
Altered immune responses in mice lacking inducible nitric oxide synthase
-
Wei, X. Q., Charles, I. G., Smith, A., Ure, J., Feng, G. J., Huang, F. P., Xu, D., Muller, W., Moncada, S., Liew, F. Y. (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 375, 408-411.
-
(1995)
Nature
, vol.375
, pp. 408-411
-
-
Wei, X.Q.1
Charles, I.G.2
Smith, A.3
Ure, J.4
Feng, G.J.5
Huang, F.P.6
Xu, D.7
Muller, W.8
Moncada, S.9
Liew, F.Y.10
-
362
-
-
0031818013
-
Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection
-
Karupiah, G., Chen, J. H., Nathan, C. F., Mahalingam, S., MacMicking, J. D. (1998) Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection. J. Virol. 72, 7703-7706.
-
(1998)
J. Virol.
, vol.72
, pp. 7703-7706
-
-
Karupiah, G.1
Chen, J.H.2
Nathan, C.F.3
Mahalingam, S.4
MacMicking, J.D.5
-
363
-
-
0034599831
-
Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice
-
Guidotti, L. G., McClary, H., Loudis, J. M., Chisari, F. V. (2000) Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice. J. Exp. Med. 191, 1247-1252.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1247-1252
-
-
Guidotti, L.G.1
McClary, H.2
Loudis, J.M.3
Chisari, F.V.4
-
364
-
-
0024351625
-
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages
-
Kwon, N. S., Nathan, C. F., Stuehr, D. J. (1989) Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. J. Biol. Chem. 264, 20496-20501.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 20496-20501
-
-
Kwon, N.S.1
Nathan, C.F.2
Stuehr, D.J.3
-
365
-
-
0023796162
-
Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages
-
Drapier, J. C., Wietzerbin, J., Hibbs Jr., J. B. (1988) Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. 18, 1587-1592.
-
(1988)
Eur. J. Immunol.
, vol.18
, pp. 1587-1592
-
-
Drapier, J.C.1
Wietzerbin, J.2
Hibbs Jr., J.B.3
-
366
-
-
0027947675
-
New insights into the regulation of inducible nitric oxide synthesis
-
Morris Jr., S. M., Billiar, T. R. (1994) New insights into the regulation of inducible nitric oxide synthesis. Am. J. Physiol. 266, E829-E839.
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Morris Jr., S.M.1
Billiar, T.R.2
-
367
-
-
0027267486
-
Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor
-
Kamijo, R., Shapiro, D., Le, J., Huang, S., Aguet, M., Vilcek, J. (1993) Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor. Proc. Natl. Acad. Sci. USA 90, 6626-6630.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6626-6630
-
-
Kamijo, R.1
Shapiro, D.2
Le, J.3
Huang, S.4
Aguet, M.5
Vilcek, J.6
-
368
-
-
0028348307
-
Requirement for transcription factor IRF-1 in NO synthase induction in macrophages
-
Kamijo, R., Harada, H., Matsuyama, T., Bosland, M., Gerecitano, J., Shapiro, D., Le, J., Koh, S. I., Kimura, T., Green, S. J., et al. (1994) Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263, 1612-1615.
-
(1994)
Science
, vol.263
, pp. 1612-1615
-
-
Kamijo, R.1
Harada, H.2
Matsuyama, T.3
Bosland, M.4
Gerecitano, J.5
Shapiro, D.6
Le, J.7
Koh, S.I.8
Kimura, T.9
Green, S.J.10
-
369
-
-
0025874048
-
Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
-
Radi, R., Beckman, J. S., Bush, K. M., Freeman, B. A. (1991) Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288, 481-487.
-
(1991)
Arch. Biochem. Biophys.
, vol.288
, pp. 481-487
-
-
Radi, R.1
Beckman, J.S.2
Bush, K.M.3
Freeman, B.A.4
-
370
-
-
0025730414
-
Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide
-
Radi, R., Beckman, J. S., Bush, K. M., Freeman, B. A. (1991) Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266, 4244-4250.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 4244-4250
-
-
Radi, R.1
Beckman, J.S.2
Bush, K.M.3
Freeman, B.A.4
-
371
-
-
0024538657
-
Tumor necrosis factor and immune interferon synergistically induce cytochrome b-245 heavy-chain gene expression and nicotinamide-adenine dinucleotide phosphate hydrogenase oxidase in human leukemic myeloid cells
-
Cassatella, M. A., Hartman, L., Perussia, B., Trinchieri, G. (1989) Tumor necrosis factor and immune interferon synergistically induce cytochrome b-245 heavy-chain gene expression and nicotinamide-adenine dinucleotide phosphate hydrogenase oxidase in human leukemic myeloid cells. J. Clin. Invest. 83, 1570-1579.
-
(1989)
J. Clin. Invest.
, vol.83
, pp. 1570-1579
-
-
Cassatella, M.A.1
Hartman, L.2
Perussia, B.3
Trinchieri, G.4
-
372
-
-
0000056144
-
Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan
-
Pfefferkorn, E. R. (1984) Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan. Proc. Natl. Acad. Sci. USA 81, 908-912.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 908-912
-
-
Pfefferkorn, E.R.1
-
373
-
-
0028967644
-
The role of indoleamine 2,3-dioxygenase in the anti-tumour activity of human interferon-gamma in vivo
-
Burke, F., Knowles, R. G., East, N., Balkwill, F. R. (1995) The role of indoleamine 2,3-dioxygenase in the anti-tumour activity of human interferon-gamma in vivo. Int. J. Cancer 60, 115-122.
-
(1995)
Int. J. Cancer
, vol.60
, pp. 115-122
-
-
Burke, F.1
Knowles, R.G.2
East, N.3
Balkwill, F.R.4
-
374
-
-
0030813497
-
Potentiation of interferon-induced indoleamine 2,3-dioxygenase mRNA in human mononuclear phagocytes by lipopolysaccharide and interleukin-1
-
Hissong, B. D., Carlin, J. M. (1997) Potentiation of interferon-induced indoleamine 2,3-dioxygenase mRNA in human mononuclear phagocytes by lipopolysaccharide and interleukin-1. J. Interferon Cytokine Res. 17, 387-393.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 387-393
-
-
Hissong, B.D.1
Carlin, J.M.2
-
375
-
-
0023203020
-
Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures
-
Carlin, J. M., Borden, E. C., Sondel, P. M., Byrne, G. I. (1987) Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures. J. Immunol. 139, 2414-2418.
-
(1987)
J. Immunol.
, vol.139
, pp. 2414-2418
-
-
Carlin, J.M.1
Borden, E.C.2
Sondel, P.M.3
Byrne, G.I.4
-
376
-
-
0027460284
-
Differential regulation of human indoleamine 2,3-dioxygenase gene expression by interferons-gamma and -alpha. Analysis of the regulatory region of the gene and identification of an interferon-gamma-inducible DNA-binding factor
-
Hassanain, H. H., Chon, S. Y., Gupta, S. L. (1993) Differential regulation of human indoleamine 2,3-dioxygenase gene expression by interferons-gamma and -alpha. Analysis of the regulatory region of the gene and identification of an interferon-gamma-inducible DNA-binding factor. J. Biol. Chem. 268, 5077-5084.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5077-5084
-
-
Hassanain, H.H.1
Chon, S.Y.2
Gupta, S.L.3
-
377
-
-
0028951169
-
Differential regulation of the human, interferon inducible tryptophanyl-tRNA synthetase by various cytokines in cell lines
-
Fleckner, J., Martensen, P. M., Tolstrup, A. B., Kjeldgaard, N. O., Justesen, J. (1995) Differential regulation of the human, interferon inducible tryptophanyl-tRNA synthetase by various cytokines in cell lines. Cytokine 7, 70-77.
-
(1995)
Cytokine
, vol.7
, pp. 70-77
-
-
Fleckner, J.1
Martensen, P.M.2
Tolstrup, A.B.3
Kjeldgaard, N.O.4
Justesen, J.5
-
378
-
-
0027159055
-
Interferon inducibility of mammalian tryptophanyl-tRNA synthetase: New perspectives
-
Kisselev, L., Frolova, L., Haenni, A. L. (1993) Interferon inducibility of mammalian tryptophanyl-tRNA synthetase: new perspectives. Trends Biochem. Sci. 18, 263-267.
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 263-267
-
-
Kisselev, L.1
Frolova, L.2
Haenni, A.L.3
-
379
-
-
0028840775
-
Interferon induction of human tryptophanyl-tRNA synthetase safeguards the synthesis of tryptophan-rich immunesystem proteins: A hypothesis
-
Xue, H., Wong, J. T. (1995) Interferon induction of human tryptophanyl-tRNA synthetase safeguards the synthesis of tryptophan-rich immunesystem proteins: a hypothesis. Gene 165, 335-339.
-
(1995)
Gene
, vol.165
, pp. 335-339
-
-
Xue, H.1
Wong, J.T.2
-
380
-
-
0027240518
-
Germline transcripts of the murine immunoglobulin gamma 2a gene: Structure and induction by IFN-gamma
-
Collins, J. T., Dunnick, W. A. (1993) Germline transcripts of the murine immunoglobulin gamma 2a gene: structure and induction by IFN-gamma. Int. Immunol. 5, 885-891.
-
(1993)
Int. Immunol.
, vol.5
, pp. 885-891
-
-
Collins, J.T.1
Dunnick, W.A.2
-
381
-
-
0023197097
-
Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
-
Snapper, C. M., Paul, W. E. (1987) Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236, 944-947.
-
(1987)
Science
, vol.236
, pp. 944-947
-
-
Snapper, C.M.1
Paul, W.E.2
-
382
-
-
0029890168
-
Endotoxin signal transduction in macrophages
-
Sweet, M. J., Hume, D. A. (1996) Endotoxin signal transduction in macrophages. J. Leukoc. Biol. 60, 8-26.
-
(1996)
J. Leukoc. Biol.
, vol.60
, pp. 8-26
-
-
Sweet, M.J.1
Hume, D.A.2
-
383
-
-
0034303195
-
Toll-like receptors: Lessons from knockout mice
-
Akira, S. (2000) Toll-like receptors: lessons from knockout mice. Biochem. Soc. Trans. 28, 551-556.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 551-556
-
-
Akira, S.1
-
384
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem, A., Ulevitch, R. J. (2000) Toll-like receptors in the induction of the innate immune response. Nature 406, 782-787.
-
(2000)
Nature
, vol.406
, pp. 782-787
-
-
Aderem, A.1
Ulevitch, R.J.2
-
385
-
-
0036067659
-
Toll receptors, CD14, and macrophage activation and deactivation by LPS
-
Dobrovolskaia, M. A., Vogel, S. N. (2002) Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 4, 903-914.
-
(2002)
Microbes Infect.
, vol.4
, pp. 903-914
-
-
Dobrovolskaia, M.A.1
Vogel, S.N.2
-
386
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., Adachi, O., Ogawa, T., Takeda, K., Akira, S. (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
387
-
-
0027459588
-
Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide
-
Lorsbach, R. B., Murphy, W. J., Lowenstein, C. J., Snyder, S. H., Russell, S. W. (1993) Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide. J. Biol. Chem. 268, 1908-1913.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1908-1913
-
-
Lorsbach, R.B.1
Murphy, W.J.2
Lowenstein, C.J.3
Snyder, S.H.4
Russell, S.W.5
-
388
-
-
0026049307
-
Interferon gamma increases sensitivity to endotoxin
-
Jurkovich, G. J., Mileski, W. J., Maier, R. V., Winn, R. K., Rice, C. L. (1991) Interferon gamma increases sensitivity to endotoxin. J. Surg. Res. 51, 197-203.
-
(1991)
J. Surg. Res.
, vol.51
, pp. 197-203
-
-
Jurkovich, G.J.1
Mileski, W.J.2
Maier, R.V.3
Winn, R.K.4
Rice, C.L.5
-
389
-
-
0031926060
-
IFN-gamma primes macrophage responses to bacterial DNA
-
Sweet, M. J., Stacey, K. J., Kakuda, D. K., Markovich, D., Hume, D. A. (1998) IFN-gamma primes macrophage responses to bacterial DNA. J. Interferon Cytokine Res. 18, 263-271.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 263-271
-
-
Sweet, M.J.1
Stacey, K.J.2
Kakuda, D.K.3
Markovich, D.4
Hume, D.A.5
-
390
-
-
0033673333
-
Role of type I interferons during macrophage activation by lipopolysaccharide
-
Vadiveloo, P. K., Vairo, G., Hertzog, P., Kola, I., Hamilton, J. A. (2000) Role of type I interferons during macrophage activation by lipopolysaccharide. Cytokine 12, 1639-1646.
-
(2000)
Cytokine
, vol.12
, pp. 1639-1646
-
-
Vadiveloo, P.K.1
Vairo, G.2
Hertzog, P.3
Kola, I.4
Hamilton, J.A.5
-
391
-
-
0842266200
-
The regulation and function of murine PAI-2
-
Brisbane, Australia, Biochemistry Department, University of Queensland
-
Costelloe, E. A. (1997) The regulation and function of murine PAI-2. In Centre for Molecular and Cellular Biology, Brisbane, Australia, Biochemistry Department, University of Queensland, 158.
-
(1997)
Centre for Molecular and Cellular Biology
, pp. 158
-
-
Costelloe, E.A.1
-
392
-
-
0027092603
-
Macrophage priming by interferon gamma: A selective process with potentially harmful effects
-
Williams, J. G., Jurkovich, G. J., Hahnel, G. B., Maier, R. V. (1992) Macrophage priming by interferon gamma: a selective process with potentially harmful effects. J. Leukoc. Biol. 52, 579-584.
-
(1992)
J. Leukoc. Biol.
, vol.52
, pp. 579-584
-
-
Williams, J.G.1
Jurkovich, G.J.2
Hahnel, G.B.3
Maier, R.V.4
-
393
-
-
0028222122
-
Interferon gamma receptor deficient mice are resistant to endotoxic shock
-
Car, B. D., Eng, V. M., Schnyder, B., Ozmen, L., Huang, S., Gallay, P., Heumann, D., Aguet, M., Ryffel, B. (1994) Interferon gamma receptor deficient mice are resistant to endotoxic shock. J. Exp. Med. 179, 1437-1444.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1437-1444
-
-
Car, B.D.1
Eng, V.M.2
Schnyder, B.3
Ozmen, L.4
Huang, S.5
Gallay, P.6
Heumann, D.7
Aguet, M.8
Ryffel, B.9
-
394
-
-
0036565888
-
Stimulation of Toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: A molecular basis for priming and synergism with bacterial lipopolysaccharide
-
Bosisio, D., Polentarutti, N., Sironi, M., Bernasconi, S., Miyake, K., Webb, G. R., Martin, M. U., Mantovani, A., Muzio, M. (2002) Stimulation of Toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood 99, 3427-3431.
-
(2002)
Blood
, vol.99
, pp. 3427-3431
-
-
Bosisio, D.1
Polentarutti, N.2
Sironi, M.3
Bernasconi, S.4
Miyake, K.5
Webb, G.R.6
Martin, M.U.7
Mantovani, A.8
Muzio, M.9
-
395
-
-
0035801931
-
Toll-like receptor 2 and 4 surface expressions on human monocytes are modulated by interferon-gamma and macrophage colony-stimulating factor
-
Mita, Y., Dobashi, K., Shimizu, Y., Nakazawa, T., Mori, M. (2001) Toll-like receptor 2 and 4 surface expressions on human monocytes are modulated by interferon-gamma and macrophage colony-stimulating factor. Immunol. Lett. 78, 97-101.
-
(2001)
Immunol. Lett.
, vol.78
, pp. 97-101
-
-
Mita, Y.1
Dobashi, K.2
Shimizu, Y.3
Nakazawa, T.4
Mori, M.5
-
396
-
-
0028172911
-
Interferon-gamma and polyunsaturated fatty acids increase the binding of lipopolysaccharide to macrophages
-
Darmani, H., Parton, J., Harwood, J. L., Jackson, S. K. (1994) Interferon-gamma and polyunsaturated fatty acids increase the binding of lipopolysaccharide to macrophages. Int. J. Exp. Pathol. 75, 363-368.
-
(1994)
Int. J. Exp. Pathol.
, vol.75
, pp. 363-368
-
-
Darmani, H.1
Parton, J.2
Harwood, J.L.3
Jackson, S.K.4
-
397
-
-
0037008716
-
Gamma interferon and granulocyte/monocyte colony-stimulating factor prevent endotoxin tolerance in human monocytes by promoting interleukin-1 receptor-associated kinase expression and its association to MyD88 and not by modulating TLR4 expression
-
Adib-Conquy, M., Cavaillon, J. M. (2002) Gamma interferon and granulocyte/monocyte colony-stimulating factor prevent endotoxin tolerance in human monocytes by promoting interleukin-1 receptor-associated kinase expression and its association to MyD88 and not by modulating TLR4 expression. J. Biol. Chem. 277, 27927-27934.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27927-27934
-
-
Adib-Conquy, M.1
Cavaillon, J.M.2
-
398
-
-
0032919854
-
Gamma interferon augments macrophage activation by lipopolysaccharide by two distinct mechanisms, at the signal transduction level and via an autocrine mechanism involving tumor necrosis factor alpha and interleukin-1
-
Held, T. K., Weihua, X., Yuan, L., Kalvakolanu, D. V., Cross, A. S. (1999) Gamma interferon augments macrophage activation by lipopolysaccharide by two distinct mechanisms, at the signal transduction level and via an autocrine mechanism involving tumor necrosis factor alpha and interleukin-1. Infect. Immun. 67, 206-212.
-
(1999)
Infect. Immun.
, vol.67
, pp. 206-212
-
-
Held, T.K.1
Weihua, X.2
Yuan, L.3
Kalvakolanu, D.V.4
Cross, A.S.5
-
399
-
-
0029913451
-
Interferon-gamma modulates the lipopolysaccharide-induced expression of AP-1 and NF-kappa B at the mRNA and protein level in human monocytes
-
de Wit, H., Hoogstraten, D., Halie, R. M., Vellenga, E. (1996) Interferon-gamma modulates the lipopolysaccharide-induced expression of AP-1 and NF-kappa B at the mRNA and protein level in human monocytes. Exp. Hematol. 24, 228-235.
-
(1996)
Exp. Hematol.
, vol.24
, pp. 228-235
-
-
De Wit, H.1
Hoogstraten, D.2
Halie, R.M.3
Vellenga, E.4
-
400
-
-
0036721641
-
Complement factor B gene regulation: Synergistic effects of TNF-alpha and IFN-gamma in macrophages
-
Huang, Y., Krein, P. M., Muruve, D. A., Winston, B. W. (2002) Complement factor B gene regulation: synergistic effects of TNF-alpha and IFN-gamma in macrophages. J. Immunol. 169, 2627-2635.
-
(2002)
J. Immunol.
, vol.169
, pp. 2627-2635
-
-
Huang, Y.1
Krein, P.M.2
Muruve, D.A.3
Winston, B.W.4
-
401
-
-
0028077886
-
Synergistic activation of intercellular adhesion molecule 1 (ICAM-1) by TNF-alpha and IFN-gamma is mediated by p65/p50 and p65/c-Rel and interferon-responsive factor Stat1 alpha (p91) that can be activated by both IFN-gamma and IFN-alpha
-
Jahnke, A., Johnson, J. P. (1994) Synergistic activation of intercellular adhesion molecule 1 (ICAM-1) by TNF-alpha and IFN-gamma is mediated by p65/p50 and p65/c-Rel and interferon-responsive factor Stat1 alpha (p91) that can be activated by both IFN-gamma and IFN-alpha. FEBS Lett. 354, 220-226.
-
(1994)
FEBS Lett.
, vol.354
, pp. 220-226
-
-
Jahnke, A.1
Johnson, J.P.2
-
402
-
-
0030764347
-
Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaB beta degradation
-
Cheshire, J. L., Baldwin Jr., A. S. (1997) Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaB beta degradation. Mol. Cell. Biol. 17, 6746-6754.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6746-6754
-
-
Cheshire, J.L.1
Baldwin Jr., A.S.2
-
403
-
-
0031005027
-
Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB
-
Ohmori, Y., Schreiber, R. D., Hamilton, T. A. (1997) Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB. J. Biol. Chem. 272, 14899-14907.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14899-14907
-
-
Ohmori, Y.1
Schreiber, R.D.2
Hamilton, T.A.3
-
404
-
-
0024804113
-
Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways
-
Fujita, T., Reis, L. F., Watanabe, N., Kimura, Y., Taniguchi, T., Vilcek, J. (1989) Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways. Proc. Natl. Acad. Sci. USA 86, 9936-9940.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9936-9940
-
-
Fujita, T.1
Reis, L.F.2
Watanabe, N.3
Kimura, Y.4
Taniguchi, T.5
Vilcek, J.6
-
405
-
-
0032796494
-
Tumor necrosis factor-alpha signals to the IFN-gamma receptor complex to increase Stat1alpha activation
-
Han, Y., Rogers, N., Ransohoff, R. M. (1999) Tumor necrosis factor-alpha signals to the IFN-gamma receptor complex to increase Stat1alpha activation. J. Interferon Cytokine Res. 19, 731-740.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 731-740
-
-
Han, Y.1
Rogers, N.2
Ransohoff, R.M.3
-
406
-
-
0028332026
-
Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B
-
Kumar, A., Haque, J., Lacoste, J., Hiscott, J., Williams, B. R. (1994) Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. Proc. Natl. Acad. Sci. USA 91, 6288-6292.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6288-6292
-
-
Kumar, A.1
Haque, J.2
Lacoste, J.3
Hiscott, J.4
Williams, B.R.5
-
407
-
-
0027330893
-
IFN-gamma and lipopolysaccharide differentially modulate expression of tumor necrosis factor receptor mRNA in murine peritoneal macrophages
-
Tannenbaum, C. S., Major, J. A., Hamilton, T. A. (1993) IFN-gamma and lipopolysaccharide differentially modulate expression of tumor necrosis factor receptor mRNA in murine peritoneal macrophages. J. Immunol. 151, 6833-6839.
-
(1993)
J. Immunol.
, vol.151
, pp. 6833-6839
-
-
Tannenbaum, C.S.1
Major, J.A.2
Hamilton, T.A.3
-
408
-
-
0022377333
-
Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon
-
Aggarwal, B. B., Eessalu, T. E., Hass, P. E. (1985) Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon. Nature 318, 665-667.
-
(1985)
Nature
, vol.318
, pp. 665-667
-
-
Aggarwal, B.B.1
Eessalu, T.E.2
Hass, P.E.3
-
409
-
-
0025345605
-
Induction of tumor necrosis factor-alpha and its receptors during differentiation in myeloid leukemic cells along the monocytic pathway. A possible regulatory mechanism for TNF-alpha production
-
Michishita, M., Yoshida, Y., Uchino, H., Nagata, K. (1990) Induction of tumor necrosis factor-alpha and its receptors during differentiation in myeloid leukemic cells along the monocytic pathway. A possible regulatory mechanism for TNF-alpha production. J. Biol. Chem. 265, 8751-8759.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 8751-8759
-
-
Michishita, M.1
Yoshida, Y.2
Uchino, H.3
Nagata, K.4
-
410
-
-
0023235797
-
Induction of receptors for tumor necrosis factor-alpha by interferons is not a major mechanism for their synergistic cytotoxic response
-
Aggarwal, B. B., Eessalu, T. E. (1987) Induction of receptors for tumor necrosis factor-alpha by interferons is not a major mechanism for their synergistic cytotoxic response. J. Biol. Chem. 262, 10000-10007.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 10000-10007
-
-
Aggarwal, B.B.1
Eessalu, T.E.2
-
411
-
-
0038605053
-
Toll-like receptor 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages
-
Rhee, S. H., Jones, B. W., Toshchakov, V., Vogel, S. N., Fenton, M. J. (2003) Toll-like receptor 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages. J. Biol. Chem. 278, 22506-22512.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22506-22512
-
-
Rhee, S.H.1
Jones, B.W.2
Toshchakov, V.3
Vogel, S.N.4
Fenton, M.J.5
-
412
-
-
0001378811
-
Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: Pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene
-
Gao, J. J., Filla, M. B., Fultz, M. J., Vogel, S. N., Russell, S. W., Murphy, W. J. (1998) Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. J. Immunol. 161, 4803-4810.
-
(1998)
J. Immunol.
, vol.161
, pp. 4803-4810
-
-
Gao, J.J.1
Filla, M.B.2
Fultz, M.J.3
Vogel, S.N.4
Russell, S.W.5
Murphy, W.J.6
-
413
-
-
0024333896
-
Bacterial lipopolysaccharide and gamma interferon induce transcription of beta interferon mRNA and interferon secretion in murine macrophages
-
Gessani, S., Belardelli, F., Pecorelli, A., Puddu, P., Baglioni, C. (1989) Bacterial lipopolysaccharide and gamma interferon induce transcription of beta interferon mRNA and interferon secretion in murine macrophages. J. Virol. 63, 2785-2789.
-
(1989)
J. Virol.
, vol.63
, pp. 2785-2789
-
-
Gessani, S.1
Belardelli, F.2
Pecorelli, A.3
Puddu, P.4
Baglioni, C.5
-
414
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages
-
Toshchakov, V., Jones, B. W., Perera, P. Y., Thomas, K., Cody, M. J., Zhang, S., Williams, B. R., Major, J., Hamilton, T. A., Fenton, M. J., Vogel, S. N. (2002) TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. Nat. Immunol. 3, 392-398.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
415
-
-
0035067108
-
Requirement for STAT1 in LPS-induced gene expression in macrophages
-
Ohmori, Y., Hamilton, T. A. (2001) Requirement for STAT1 in LPS-induced gene expression in macrophages. J. Leukoc. Biol. 69, 598-604.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 598-604
-
-
Ohmori, Y.1
Hamilton, T.A.2
-
416
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai, T., Takeuchi, O., Fujita, T., Inoue, J., Muhlradt, P. F., Sato, S., Hoshino, K., Akira, S. (2001) Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167, 5887-5894.
-
(2001)
J. Immunol.
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
417
-
-
0029034506
-
The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha
-
Ohmori, Y., Hamilton, T. A. (1995) The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha. J. Immunol. 154, 5235-5244.
-
(1995)
J. Immunol.
, vol.154
, pp. 5235-5244
-
-
Ohmori, Y.1
Hamilton, T.A.2
-
418
-
-
0031022516
-
An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide
-
Gao, J., Morrison, D. C., Parmely, T. J., Russell, S. W., Murphy, W. J. (1997) An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide. J. Biol. Chem. 272, 1226-1230.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1226-1230
-
-
Gao, J.1
Morrison, D.C.2
Parmely, T.J.3
Russell, S.W.4
Murphy, W.J.5
-
419
-
-
0027939931
-
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
-
Xie, Q. W., Kashiwabara, Y., Nathan, C. (1994) Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269, 4705-4708.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4705-4708
-
-
Xie, Q.W.1
Kashiwabara, Y.2
Nathan, C.3
-
420
-
-
0028921613
-
Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers
-
Ledebur, H. C., Parks, T. P. (1995) Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers. J. Biol. Chem. 270, 933-943.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 933-943
-
-
Ledebur, H.C.1
Parks, T.P.2
-
421
-
-
0028146329
-
Stimulation of the human intercellular adhesion molecule-1 promoter by interleukin-6 and interferon-gamma involves binding of distinct factors to a palindromic response element
-
Caldenhoven, E., Coffer, P., Yuan, J., Van de Stolpe, A., Horn, F., Kruijer, W., Van der Saag, P. T. (1994) Stimulation of the human intercellular adhesion molecule-1 promoter by interleukin-6 and interferon-gamma involves binding of distinct factors to a palindromic response element. J. Biol. Chem. 269, 21146-21154.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21146-21154
-
-
Caldenhoven, E.1
Coffer, P.2
Yuan, J.3
Van De Stolpe, A.4
Horn, F.5
Kruijer, W.6
Van Der Saag, P.T.7
-
422
-
-
0028362627
-
Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells
-
Look, D. C., Pelletier, M. R., Holtzman, M. J. (1994) Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. J. Biol. Chem. 269, 8952-8958.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8952-8958
-
-
Look, D.C.1
Pelletier, M.R.2
Holtzman, M.J.3
-
423
-
-
0034307684
-
Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression
-
Hume, D. A. (2000) Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression. Blood 96, 2323-2328.
-
(2000)
Blood
, vol.96
, pp. 2323-2328
-
-
Hume, D.A.1
|