STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication

Journal of Virology

Volumn 76, Issue 13, 2002, Pages 6435-6441

  Parisien, Jean Patrick ^a   Lau, Joe F ^a   Horvath, Curt M ^a  

^a East Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; COMPLEMENTARY DNA; INTERFERON; STAT2 PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; GENE ACTIVATION; GENE INDUCTION; HOST RANGE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOUSE; NONHUMAN; PARAINFLUENZA VIRUS 2; PARAMYXOVIRUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SIMIAN VIRUS; SPECIES DIFFERENCE; VIRUS REPLICATION;

3T3 CELLS; ANIMALS; CELL LINE; DNA-BINDING PROTEINS; HUMANS; INTERFERON-ALPHA; INTERFERON-BETA; MICE; PARAINFLUENZA VIRUS 2, HUMAN; RUBULAVIRUS; SPECIES SPECIFICITY; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; VIRAL STRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 0036284219     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.13.6435-6441.2002     Document Type: Article

References (29)

1. Evolution of cell recognition by viruses
2. Nipah virus: A recently emergent deadly paramyxovirus
3. Sendai virus and simian virus 5 block activation of interferon-responsive genes: Importance for virus pathogenesis
4. The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation
5. Selective loss of type 1 interferon induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
6. Longer and shorter forms of Sendai virus C proteins play different roles in modulating the cellular antiviral response
7. Sendai virus C proteins must interact directly with cellular components to interfere with interferon action
8. Sendai virus C proteins counteract the interferon-mediated induction of an antiviral state
9. Interferons: Cell signalling, immune modulation, antiviral response and virus countermeasures
10. Recovery of infectious SV5 from cloned DNA and expression of a foreign gene
11. STAT proteins and transcriptional responses to extra-cellular signals
12. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
13. Incomplete replication of human parainfluenza virus type 2 in mouse L929 cells
14. RNA replication from the simian virus 5 antigenomic promoter requires three sequence-dependent elements separated by sequence-independent spacer regions
15. C terminal CYS-RICH region of mumps virus structural V protein correlates with block of interferon alpha and gamma signal transduction pathway through decrease of STAT 1-alpha
16. High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons
17. Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
18. Complementation of a mutant cell line: Central role of the 91-kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway
19. Evasion of host defenses by measles virus: Wild-type measles virus infection interferes with induction of alpha/beta interferon production
20. High resistance of human parainfluenza type 2 virus protein-expressing cells to the antiviral and anti-cell proliferative activities of alpha/beta interferons: Cysteine-rich V-specific domain is required for high resistance to the interferons
21. The V protein of human parainfluenza virus 2 antagonizes type 1 interferon responses by destabilizing signal transducer and activator of transcription 2
22. Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2, but is independent of alpha/beta interferon signal transduction
23. Murine Stat2 is uncharacteristically divergent
24. The paramyxovirus SV5 V protein binds two atoms of zinc and is a structural component of virions
25. Stat protein transactivation domains recruit p300/CBP through widely divergent sequences
26. Viral subversion of the immune system
27. Molecular biology of Hendra and Nipah viruses
28. Single amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cells
29. Isolation of highly fusogenic variants of simian virus 5 from persistently infected cells that produce and respond to interferon