Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: Determinants of its pathogenicity?

Journal of Virology

Volumn 71, Issue 6, 1997, Pages 4187-4192

  Neipel, Frank ^a   Albrecht, Jens Christian ^a   Fleckenstein, Bernhard ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; EPSTEIN BARR VIRUS; HERPES VIRUS; HUMAN; KAPOSI SARCOMA; NUCLEOTIDE SEQUENCE; PATHOGENICITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW; SEQUENCE HOMOLOGY; SEXUALLY TRANSMITTED DISEASE; VIRUS GENE;

EID: 0030925274     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.6.4187-4192.1997     Document Type: Review

References (68)

1. Albini, A., M. G. Aluigi, R. Benelli, E. Berti, P. Biberfeld, C. Blasig, M. L. Calabro, F. Calvo, L. Chieco-Bianchi, M. Corbellino, A. Del Mistro, M. Ekman, A. Favero, P. H. Hofschneider, E. Kaaya, C. Lebbe, P. Morel, F. Neipel, D. M. Noonan, C. Parravicini, L. Repetto, M. Schalling, M. Stürzl, and E. Tschachler. 1996. Oncogenesis in HIV-infection: KSHV and Kaposi's sarcoma. Int. J. Oncol. 9:5-8.
2. Albrecht, J.-C., J. Nicholas, D. Biller, K. R. Cameron, B. Biesinger, C. Newman, S. Wittmann, M. A. Craxton, H. Coleman, B. Fleckenstein, and R. W. Honess. 1992. Primary structure of the herpesvirus saimiri genome. J. Virol. 66:5047-5058.
3. Albrecht, J.-C., J. Nicholas, K. R. Cameron, C. Newman, B. Fleckenstein, and R. W. Honess. 1992. Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59. Virology 190:527-530.
4. Beral, V., T. A. Peterman, R. L. Berkelman, and H. W. Jaffe. 1990. Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection? Lancet 335:123-128.
5. Birkenbach, M., K. Josefsen, R. Yalamanchili, G. Lenoir, and E. Kieff. 1993. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 67:2209-2220.
6. Bornkamm, G. W., H. Delius, B. Fleckenstein, F.-J. Werner, and C. Mulder. 1976. Structure of herpesvirus saimiri [sic] genomes: arrangement of heavy and light sequences in the M genome. J. Virol. 19:154-161.
7. Boshoff, C., T. F. Schulz, M. M. Kennedy, A. K. Graham, C. Fisher, A. Thomas, J. O. McGee, R. A. Weiss, and J. J. O'Leary. 1995. Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells. Nature Med. 1:1274-1278.
8. Boshoff, C., S. Talbot, M. Kennedy, J. O'Leary, T. Schulz, and Y. Chang. 1996. HHV8 and skin cancers in immunosuppressed patients. Lancet 348: 138.
9. Boyd, J. M., G. J. Gallo, B. Elangovan, A. B. Houghton, S. Malstrom, B. J. Avery, R. G. Ebb, T. Surbramanian, T. Chittenden, R. J. Lutz, and G. Chinnadurai. 1995. Bik, a novel death-inducing protein, shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene 11:1921-1928.
10. Burgstahler, R., B. Kempkes, K. Steube, and M. Lipp. 1995. Expression of the chemokine receptor BLR2/EBI1 is specifically transactivated by Epstein-Barr virus nuclear antigen 2. Biochem. Biophys. Res. Commun. 215:737-743.
11. Cesarman, E., Y. Chang, P. S. Moore, J. W. Said, and D. M. Knowles. 1995. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med. 332:1186-1191.
12. Cesarman, E., P. S. Moore, P. H. Rao, G. Inghirami, D. M. Knowles, and Y. Chang. 1995. In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences. Blood 86:2708-2714.
13. Cesarman, E., R. G. Nador, F. Bai, R. A. Bohenzky, J. J. Russo, P. S. Moore, Y. Chang, and D. M. Knowles. 1996. Kaposi's sarcoma-associated herpesvirus contains G protein-coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma. J. Virol. 70:8218-8223.
14. Chang, Y., E. Cesarman, M. S. Pessin, F. Lee, J. Culpepper, D. M. Knowles, and P. S. Moore. 1994. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 226:1865-1869.
15. Chang, Y., P. S. Moore, S. J. Talbot, C. H. Boshoff, T. Zarkowska, K. Godden, H. Paterson, R. A. Weiss, and S. Mittnacht. 1996. Cyclin encoded by KS herpesvirus. Nature 382:410-411.
16. Chang, Y., J. Ziegler, H. Wabinga, E. Katangole Mbidde, C. Boshoff, T. Schulz, D. Whitby, D. Maddalena, H. W. Jaffe, R. A. Weiss, and P. S. Moore. 1996. Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group. Arch. Intern. Med. 156:202-204.
17. Corbellino, M., G. Bestetti, M. Galli, and C. Parravicini. 1996. Absence of HHV-8 in prostate and semen. N. Engl. Med. 335:1237.
18. Dupin, N., M. Grandadam, V. Calvez, I. Gorin, J. T. Aubin, S. Harvard, F. Lamy, M. Leibowitch, J. M. Huraux, J. P. Escande, and H. Agut. 1995. Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma. Lancet 345:761-762.
19. 18a. Ensser, A. personal communication.
20. Fleckenstein, B., and R. C. Desrosiers. 1982. Herpesvirus saimiri and herpesvirus ateles, p. 253-331. In B. Roizman (ed.), The herpesviruses. Plenum Press, New York, N.Y.
21. Gao, S. J., L. Kingsley, M. Li, W. Zheng, C. Parravicini, J. Ziegler, R. Newton, C. R. Rinaldo, A. Saah, J. Phair, R. Detels, Y. Chang, and P. S. Moore. 1996. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nature Med. 2:925-928.
22. Gompels, U. A., and F. C. Kasolo. 1996. HHV-8 serology and Kaposi's sarcoma. Lancet 348:1587-1588.
23. Hallas, C., F. Neipel, C. Hüttner, D. Schreiner, B. Fleckenstein, and H. K. Müller-Hermelink. 1996. Presence of human herpesvirus type 6 in sporadic lymphoproliferative disorders - a comparative study. Diagn. Mol. Pathol. 5:166-172.
24. Henderson, B. E., R. K. Ross, and M. C. Pike. 1991. Toward the primary prevention of cancer. Science 254:1131-1138.
25. Huang, Y. Q., J. J. Li, M. H. Kaplan, B. Poiesz, E. Katabira, W. C. Zhang, D. Feiner, and A. E. Friedman-Kien. 1995. Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma. Lancet 345:759-761.
26. Jahan, N., A. Razzaque, J. Greenspan, M. A. Conant, S. F. Josephs, S. Nakamura, and L. J. Rosenthal. 1989. Analysis of human KS biopsies and cloned cell lines for cytomegalovirus, HIV-1, and other selected DNA virus sequences. AIDS Res. Hum. Retroviruses 5:225-231.
27. Kaaya, E. E., C. Parravicini, C. Ordonez, R. Gendelman, E. Berti, R. C. Gallo, and P. Biberfeld. 1995. Heterogeneity of spindle cells in Kaposi's sarcoma: comparison of cells in lesions and in culture. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 10:295-305.
28. Kaschka-Dierich, C., F. J. Werner, I. Bauer, and B. Fleckenstein. 1982. Structure of nonintegrated, circular herpesvirus saimiri [sic] and herpesvirus ateles [sic] genomes in tumor cell lines and in vitro-transformed cells. J. Virol. 44:295-310.
29. Kedes, D., E. Operalski, M. Busch, R. Kohn, J. Flood, and D. E. Ganem. 1996. The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nature Med. 2:918-924.
30. Kempf, W., V. Adams, S. Hassam, M. Schmid, R. Moss, J. Briner, and M. Pfaltz. 1994. Detection of human herpesvirus type 6, human herpesvirus type 7, cytomegalovirus and human papillomavirus in cutaneous AIDS-associated Kaposi's sarcoma. Verh. Dtsch. Ges. Pathol. 78:260-264. (In German.)
31. Kempf, W., V. Adams, M. Pfaltz, J. Briner, M. Schmid, R. Moss, and S. Hassam. 1995. Human herpesvirus type 6 and cytomegalovirus in AIDS-associated Kaposi's sarcoma: no evidence for an etiological association. Hum. Pathol. 26:914-919.
32. Larcher, C., B. Kempkes, E. Kremmer, W. M. Prodinger, M. Pawlita, G. W. Bornkamm, and M. P. Dierich. 1995. Expression of Epstein-Barr virus nuclear antigen-2 (EBNA2) induces CD21/CR2 on B and T cell lines and shedding of soluble CD21. Eur. J. Immunol. 25:1713-1719.
33. Lennette, E. T., D. J. Blackbourn, and J. A. Levy. 1996. Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 348:858-861.
34. Li, M., H. Lee, D.-W. Yoon, J.-C. Albrecht, B. Fleckenstein, F. Neipel, and J. U. Jung. 1997. Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin. J. Virol. 71:1984-1991.
35. Lin, J. C., S. C. Lin, E. C. Mar, P. E. Pellett, F. R. Stamey, J. A. Stewart, and T. J. Spira. 1995. Is Kaposi's-sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men? Lancet 346:1601-1602.
36. Lisitsyn, N. A., N. M. Lisitsyn, and M. Wigler. 1993. Cloning the differences between two complex genomes. Science 259:946-951.
37. Marchioli, C. C., J. L. Love, L. Z. Abbott, Y. Q. Huang, S. C. Remick, N. Surtento-Reodica, R. E. Hutchison, D. Mildvan, A. E. Friedman-Kien, and B. J. Poiesz. 1996. Prevalence of human herpesvirus 8 DNA sequences in several patient populations. J. Clin. Microbiol. 34:2635-2638.
38. Masood, R., Y. Lunardi-Iskandar, L. F. Jean, J. R. Murphy, C. Waters, R. C. Gallo, and P. Gill. 1994. Inhibition of AIDS-associated Kaposi's sarcoma cell growth by DAB389-interleukin 6. AIDS Res. Hum. Retroviruses 10:969-975.
39. Mesri, E. A., E. Cesarman, L. Arvanitakis, S. Rafii, M. A. Moore, D. N. Posnett, D. M. Knowles, and A. S. Asch. 1996. Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells. J. Exp. Med. 183:2385-2390.
40. Miles, S. A. 1992. Pathogenesis of human immunodeficiency virus-related Kaposi's sarcoma. Curr. Opin. Oncol. 4:875-882.
41. Miles, S. A., A. R. Rezai, J. F. Salazar-Gonzalez, M. Vander Meyden, R. H. Stevens, D. M. Logan, R. T. Mitsuyasu, T. Taga, T. Hirano, T. Kishimoto, and O. Martinez-Maza. 1990. AIDS Kaposi's sarcoma-derived cells produce and respond to interleukin 6. Proc. Natl. Acad. Sci. USA 87:4068-4072.
42. Miller, G., M. O. Rigsby, L. Heston, E. Grogan, R. Sun, C. Metroka, J. A. Levy, S. J. Gao, Y. Chang, and P. Moore. 1996. Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. N. Engl. J. Med. 334:1292-1297.
43. Monini, P., L. de Lellis, M. Fabris, F. Rigolin, and E. Cassai. 1996. Kaposi's sarcoma-associated herpesvirus DNA sequences in prostate tissue and human semen. N. Engl. J. Med. 334:1168-1172.
44. Monini, P., A. Rotola, L. de Lellis, A. Corallini, P. Secchiero, A. Albini, R. Benelli, C. Parravicini, G. Barbanti Brodano, and E. Cassai. 1996. Lancet BK virus infection and Kaposi's sarcoma pathogenesis. Int. J. Cancer 66: 717-722.
45. Moore, P. S., C. Boshoff, R. A. Weiss, and Y. Chang. 1996. Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 274:1739-1744.
46. Moore, P. S., S.-J. Gao, G. Dominguez, E. Cesarman, O. Lungu, D. M. Knowles, R. Garber, P. E. Pellett, D. J. McGeoch, and Y. Chang. 1996. Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J. Virol. 70:549-558.
47. Murakami Mori, K., T. Taga, T. Kishimoto, and S. Nakamura. 1995. AIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodies. J. Clin. Invest. 96:1319-1327.
48. Neipel, F., J.-C. Albrecht, A. Ensser, Y.-Q. Huang, J. J. Li, A. E. Friedman-Kien, and B. Fleckenstein. 1997. Primary structure of the Kaposi's sarcoma-associated human herpesvirus 8. Genbank accession no. U93872.
49. Neipel, F., J.-C. Albrecht, A. Ensser, Y.-Q. Huang, J. J. Li, A. E. Friedman-Kien, and B. Fleckenstein. 1997. Human herpesvirus 8 encodes a homolog of interleukin-6. J. Virol. 71:839-842.
50. Rady, P. L., A. Yen, J. L. Rollefson, I. Orengo, S. Bruce, T. K. Hughes, and S. K. Tyring. 1995. Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients. Lancet 345:1339-1340.
51. Renne, R., M. Lagunoff, W. Zhong, and D. Ganem. 1996. The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions. J. Virol. 70:8151-8154.
52. Rickinson, A. B. 1996. Changing seroepidemiology of HHV-8. Lancet 348: 1110-1111.
53. Roizman, B., L. E. Carmichael, F. Deinhardt, G. de The, A. J. Nahmias, W. Plowright, F. Rapp, P. Sheldrick, M. Takahashi, and K. Wolf. 1981. Herpesviridae. Definition, provisional nomenclature, and taxonomy. The Herpesvirus Study Group, the International Committee on Taxonomy of Viruses. Intervirology 16:201-217.
54. Rüger, R., R. Colimon, and B. Fleckenstein. 1984. Search for DNA sequences of human cytomegalovirus in Kaposi's sarcoma tissue with cloned probes - preliminary report, p. 43-47. In G. Giraldo and E. Beth (ed.), Epidemic of acquired immune deficiency syndrome (AIDS) and Kaposi's sarcoma. S. Karger, Basel, Switzerland.
55. Russo, J. J., R. A. Bohenzky, M. C. Chen, J. Chen, M. Yan, D. Maddalena, J. P. Parry, D. Peruzzi, I. S. Edelman, Y. Chang, and P. S. Moore. 1996. Nucleotide sequence of the Kaposi's sarcoma-associated herpesvirus (HHV8). Proc. Natl. Acad. Sci. USA 93:14862-14867.
56. Sato, T., M. Hanada, S. Bodrug, S. Irie, N. Iwama, L. H. Boise, C. B. Thompson, E. Golemis, L. Fong, H. G. Wang, and J. C. Reed. 1994. Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system. Proc. Natl. Acad. Sci. USA 91:9238-9242.
57. Scala, G., M. R. Ruocco, C. Ambrosino, M. Mallardo, V. Giordano, F. Baldassarre, E. Dragonetti, I. Quinto, and S. Venuta. 1994. The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein. J. Exp. Med. 179:961-971.
58. Siegal, B., S. Levinton-Kriss, A. Schiffer, J. Sayar, I. Engelberg, A. Vonsover, Y. Ramon, and E. Rubinstein. 1990. Kaposi's sarcoma in immunosuppression. Possibly the result of a dual viral infection. Cancer 65:492-498.
59. Simpson, G. R., T. F. Schulz, D. Whitby, P. M. Cook, C. Boshoff, L. Rainbow, M. R. Howard, S. J. Gao, R. A. Bohenzky, P. Simmonds, C. Lee, A. de Ruiter, A. Hatzakis, R. S. Tedder, I. V. D. Weller, R. A. Weiss, and P. S. Moore. 1996. Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 348:1133-1138.
60. Sinclair, A. J., I. Palmero, G. Peters, and P. J. Farrell. 1994. EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus. EMBO J. 13:3321-3328.
61. Soulier, J., L. Grollet, E. Oksenhendler, P. Cacoub, D. Cazals-Hatem, P. Babinet, M. F. d'Agay, J. P. Clauvel, M. Raphael, L. Degos, and F. Sigaux. 1995. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86:1276-1280.
62. Staskus, K. A., W. Zhong, K. Gebhard, B. Herndier, H. Wang, R. Renne, J. Beneke, J. Pudney, D. J. Anderson, D. Ganem, and A. T. Haase. 1997. Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells. J. Virol. 71:715-719.
63. Stürzl, M., H. Brandstetter, C. Zietz, B. Eisenburg, G. Raivich, D. P. Gearing, N. H. Brockmeyer, and P. H. Hofschneider. 1995. Identification of interleukin-1 and platelet-derived growth factor-B as major mitogens for the spindle cells of Kaposi's sarcoma: a combined in vitro and in vivo analysis. Oncogene 10:2007-2016.
64. 62a. Stürzl, M. Personal communication.
65. Tanner, J. E., C. Alfieri, T. A. Chatila, and F. Diaz-Mitoma. 1996. Induction of interleukin-6 after stimulation of human B-cell CD21 by Epstein-Barr virus glycoproteins gp 350 and gp220. J. Virol. 70:570-575.
66. Tasaka, T., J. W. Said, and H. P. Koeffler. 1996. Absnece of HHV-8 in prostate and semen. N. Engl. J. Med. 335:1237-1238.
67. Telford, E. A., M. S. Watson, H. C. Aird, J. Perry, and A. J. Davison. 1995. The DNA sequence of equine herpesvirus 2. J. Mol. Biol. 249:520-528.
68. Zhong, W., H. Wang, B. Herndier, and D. Ganem. 1996. Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc. Natl. Acad. Sci. USA 93:6641-6646.