-
1
-
-
0031889797
-
A perspective on the clinical effectiveness and tolerance of interferon-α
-
Borden, E.C. and Parkinson, D. (1998) A perspective on the clinical effectiveness and tolerance of interferon-α. Semin. Oncol., 25, 3-8.
-
(1998)
Semin. Oncol.
, vol.25
, pp. 3-8
-
-
Borden, E.C.1
Parkinson, D.2
-
2
-
-
0030919654
-
Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets
-
Borsch-Haubold, A.G., Kramer, R.M. and Watson, S.P. (1997) Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets. Eur. J. Biochem., 245, 751-759.
-
(1997)
Eur. J. Biochem.
, vol.245
, pp. 751-759
-
-
Borsch-Haubold, A.G.1
Kramer, R.M.2
Watson, S.P.3
-
3
-
-
0029799912
-
Transcriptionally active STAT1 is required for the antiproliferative effects of both interferon α and interferon γ
-
Bromberg, J.F., Horvath, C.M., Wen, Z., Schreiber, R.D. and Darnell, J.E. (1996) Transcriptionally active STAT1 is required for the antiproliferative effects of both interferon α and interferon γ. Proc. Natl Acad. Sci. USA, 93, 7673-7678.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 7673-7678
-
-
Bromberg, J.F.1
Horvath, C.M.2
Wen, Z.3
Schreiber, R.D.4
Darnell, J.E.5
-
4
-
-
0030469719
-
Activation of STAT4 by IL-12 and IFN-α: Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
-
Cho, S.S., Bacon, C.M., Sudarshan, C., Rees, R.C., Finbloom, D., Pine, R. and O'Shea, J.J. (1996) Activation of STAT4 by IL-12 and IFN-α: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. J. Immunol., 157, 4781-4789.
-
(1996)
J. Immunol.
, vol.157
, pp. 4781-4789
-
-
Cho, S.S.1
Bacon, C.M.2
Sudarshan, C.3
Rees, R.C.4
Finbloom, D.5
Pine, R.6
O'Shea, J.J.7
-
5
-
-
0030772458
-
STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
-
Chung, J., Uchida, E., Grammer, T.C. and Blenis, J. (1997) STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Mol. Cell. Biol., 17, 6508-6516.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6508-6516
-
-
Chung, J.1
Uchida, E.2
Grammer, T.C.3
Blenis, J.4
-
6
-
-
0029133702
-
Requirement for MAP kinase (ERK2) activity in interferon α- and interferon β-stimulated gene expression through STAT proteins
-
David, M., Petricoin, E.F.,III, Benjamin, C., Pine, R., Weber, M.J. and Larner, A.C. (1995) Requirement for MAP kinase (ERK2) activity in interferon α- and interferon β-stimulated gene expression through STAT proteins. Science, 269, 1721-1723.
-
(1995)
Science
, vol.269
, pp. 1721-1723
-
-
David, M.1
Petricoin III, E.F.2
Benjamin, C.3
Pine, R.4
Weber, M.J.5
Larner, A.C.6
-
7
-
-
0030038677
-
The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon α/β-induced gene expression
-
David, M., Zhou, G., Pin, R., Dixon, J.E. and Larner, A.C. (1996) The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon α/β-induced gene expression. J. Biol. Chem., 271, 15862-15865.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15862-15865
-
-
David, M.1
Zhou, G.2
Pin, R.3
Dixon, J.E.4
Larner, A.C.5
-
8
-
-
0032417696
-
Identification of genes differentially regulated by interferon α, β or γ using oligonucleotide arrays
-
Der, S.D., Zhou, A., Williams, B.R.G. and Silverman, R.H. (1998) Identification of genes differentially regulated by interferon α, β or γ using oligonucleotide arrays. Proc. Natl Acad. Sci. USA, 95, 15623-15628.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 15623-15628
-
-
Der, S.D.1
Zhou, A.2
Williams, B.R.G.3
Silverman, R.H.4
-
9
-
-
0033610788
-
Specific inhibitors of p38 MAPK block 3T3-L1 adipogenesis
-
Engelman, J.A., Lisanti, M.P. and Scherer, P.E. (1998) Specific inhibitors of p38 MAPK block 3T3-L1 adipogenesis. J. Biol. Chem., 273, 32111-32120.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32111-32120
-
-
Engelman, J.A.1
Lisanti, M.P.2
Scherer, P.E.3
-
10
-
-
0031916832
-
Selective activation of p38 MAP kinase isoforms by the MAP kinase kinases MKK3 and MKK6
-
Enslen, H., Raingeaud, J. and Davis, R.J. (1998) Selective activation of p38 MAP kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J. Biol. Chem., 273, 1741-1748.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1741-1748
-
-
Enslen, H.1
Raingeaud, J.2
Davis, R.J.3
-
11
-
-
0029670488
-
Interferon-α-induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon-stimulated gene factor three
-
Flati, V., Haque, S.J. and Williams, B.R.G. (1996) Interferon-α-induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon-stimulated gene factor three. EMBO J., 15, 1566-1571.
-
(1996)
EMBO J.
, vol.15
, pp. 1566-1571
-
-
Flati, V.1
Haque, S.J.2
Williams, B.R.G.3
-
12
-
-
0033561559
-
The functional synergy between IL-12 and IL-2 involves p38 MAP kinase and is associated with the augmentation of STAT serine phosphorylation
-
Gollob, J.A., Schnipper, C.P., Murphy, E.A., Ritz, J. and Frank, D.A. (1999) The functional synergy between IL-12 and IL-2 involves p38 MAP kinase and is associated with the augmentation of STAT serine phosphorylation. J. Immunol., 162, 4472-4481.
-
(1999)
J. Immunol.
, vol.162
, pp. 4472-4481
-
-
Gollob, J.A.1
Schnipper, C.P.2
Murphy, E.A.3
Ritz, J.4
Frank, D.A.5
-
13
-
-
0026027850
-
Signal transduction by IFN-α through arachidonic acid metabolism
-
Hannigan, G.E. and Williams, B.R.G. (1991) Signal transduction by IFN-α through arachidonic acid metabolism. Science, 251, 204-207.
-
(1991)
Science
, vol.251
, pp. 204-207
-
-
Hannigan, G.E.1
Williams, B.R.G.2
-
14
-
-
0031037363
-
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300
-
Horvai, A.E., Xu, L., Korzus, E., Brard, G., Kalafus, D., Mullen, T.M., Rose, D.W., Rosenfeld, M.G. and Glass, C.K. (1997) Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc. Natl Acad. Sci. USA, 94, 1074-1079.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 1074-1079
-
-
Horvai, A.E.1
Xu, L.2
Korzus, E.3
Brard, G.4
Kalafus, D.5
Mullen, T.M.6
Rose, D.W.7
Rosenfeld, M.G.8
Glass, C.K.9
-
15
-
-
0029655458
-
The antiviral state induced by α and γ interferon requires transcriptionally active STAT1 protein
-
Horvath, C.M. and Darnell, J.E. (1996) The antiviral state induced by α and γ interferon requires transcriptionally active STAT1 protein. J. Virol., 70, 647-650.
-
(1996)
J. Virol.
, vol.70
, pp. 647-650
-
-
Horvath, C.M.1
Darnell, J.E.2
-
16
-
-
0033548678
-
Role of interleukin (IL)-2 receptor β-chain subdomains and Shc in p38 mitogen-activated protein (MAP) kinase and p54 MAP kinase (stress-activated protein Kinase/c-Jun N-terminal kinase) activation
-
Hunt, A.E., Lali, F.V., Lord, J.D., Nelson, B.H., Miyazaki, T., Tracey, K.J. and Foxwell, B.M. (1999) Role of interleukin (IL)-2 receptor β-chain subdomains and Shc in p38 mitogen-activated protein (MAP) kinase and p54 MAP kinase (stress-activated protein Kinase/c-Jun N-terminal kinase) activation. J. Biol. Chem., 274, 7591-7597.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7591-7597
-
-
Hunt, A.E.1
Lali, F.V.2
Lord, J.D.3
Nelson, B.H.4
Miyazaki, T.5
Tracey, K.J.6
Foxwell, B.M.7
-
17
-
-
0032212557
-
Purification and activation of recombinant p38 isoforms α, β, γ and δ
-
Kessler, G.A. et al. (1998) Purification and activation of recombinant p38 isoforms α, β, γ and δ. Protein Expr. Purif., 14, 221-228.
-
(1998)
Protein Expr. Purif.
, vol.14
, pp. 221-228
-
-
Kessler, G.A.1
-
18
-
-
0032127465
-
STAT1 combines signals derived from IFN-γ and LPS receptors during macrophage activation
-
Kovarik, P., Stoiber, D., Novy, M. and Decker, T. (1998) STAT1 combines signals derived from IFN-γ and LPS receptors during macrophage activation. EMBO J., 17, 3660-3668.
-
(1998)
EMBO J.
, vol.17
, pp. 3660-3668
-
-
Kovarik, P.1
Stoiber, D.2
Novy, M.3
Decker, T.4
-
19
-
-
0029911368
-
p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets
-
Kramer, R.M., Roberts, E.F., Um, S.L., Borsch-Haubold, A.G., Watson, S.P., Fisher, M.J. and Jakubowski, J.A. (1996) p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. J. Biol. Chem., 271, 27723-27729.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27723-27729
-
-
Kramer, R.M.1
Roberts, E.F.2
Um, S.L.3
Borsch-Haubold, A.G.4
Watson, S.P.5
Fisher, M.J.6
Jakubowski, J.A.7
-
20
-
-
0030659512
-
Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
-
Kumar, A., Commane, M., Flickinger, T.W., Horvath, C.M. and Stark, G.R. (1997) Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science, 278, 1630-1632.
-
(1997)
Science
, vol.278
, pp. 1630-1632
-
-
Kumar, A.1
Commane, M.2
Flickinger, T.W.3
Horvath, C.M.4
Stark, G.R.5
-
21
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee, J.C. et al. (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature, 372, 739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
-
22
-
-
0031441901
-
Antiproliferative action of interferon-α requires components of T-cell-receptor signalling
-
Petricoin, E.F., III, et al. (1997) Antiproliferative action of interferon-α requires components of T-cell-receptor signalling. Nature, 390, 629-632.
-
(1997)
Nature
, vol.390
, pp. 629-632
-
-
Petricoin III, E.F.1
-
23
-
-
0023731515
-
Interferon response element of the human gene 6-16
-
Porter, A.C.G., Chernajovsky, Y., Dale, T.C., Gilbert, C.S., Stark, G.R. and Kerr, I.M. (1988) Interferon response element of the human gene 6-16. EMBO J., 7, 85-92.
-
(1988)
EMBO J.
, vol.7
, pp. 85-92
-
-
Porter, A.C.G.1
Chernajovsky, Y.2
Dale, T.C.3
Gilbert, C.S.4
Stark, G.R.5
Kerr, I.M.6
-
24
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
Raingeaud, J., Gupta, S., Rogers, J.S., Dickens, M., Han, J., Ulevitch, R.J. and Davis, R.J. (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem., 270, 7420-7426.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
25
-
-
0030051528
-
MKK3- and MKK-6-regulated gene expression is mediated by the p38 MAPK signal transduction pathway
-
Raingeaud, J., Whitmarsh, A.J., Barrett, T., Derijard, B. and Davis, R. (1996) MKK3- and MKK-6-regulated gene expression is mediated by the p38 MAPK signal transduction pathway. Mol. Cell. Biol., 16, 1247-1255.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Derijard, B.4
Davis, R.5
-
26
-
-
0031463551
-
Regulation of NF-kB activation by MAP kinase cascade
-
Schulze-Osthoff, K., Ferrari, D., Riehemann, K. and Wesselborg, S. (1997) Regulation of NF-kB activation by MAP kinase cascade. Immunobiology, 198, 35-49.
-
(1997)
Immunobiology
, vol.198
, pp. 35-49
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Riehemann, K.3
Wesselborg, S.4
-
27
-
-
0031657551
-
How cells respond to interferons
-
Stark, G.R., Kerr, I.M., Williams, B.R.G., Silverman, R.H. and Schreiber, R.D. (1998) How cells respond to interferons. Annu. Rev. Biochem., 67, 227-264.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.G.3
Silverman, R.H.4
Schreiber, R.D.5
-
28
-
-
0028982917
-
Interferon-α engages the IRS-1 to associate with the PI 3-kinase
-
Uddin, S., Yenush, L., Sun, X.J., Sweet, M.E., White, M.F. and Platanias, L.C. (1995) Interferon-α engages the IRS-1 to associate with the PI 3-kinase. J. Biol. Chem., 270, 15938-15941.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15938-15941
-
-
Uddin, S.1
Yenush, L.2
Sun, X.J.3
Sweet, M.E.4
White, M.F.5
Platanias, L.C.6
-
29
-
-
0030865679
-
The IRS pathway operates distinctively from the STAT pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-α receptors
-
Uddin, S., Fish, E.N., Sher, D., Gardziola, C., Colamonici, O.R., Kellum, M., Pitha, P.M., White, M.F. and Platanias, L.C. (1997) The IRS pathway operates distinctively from the STAT pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-α receptors. Blood, 90, 2574-2582.
-
(1997)
Blood
, vol.90
, pp. 2574-2582
-
-
Uddin, S.1
Fish, E.N.2
Sher, D.3
Gardziola, C.4
Colamonici, O.R.5
Kellum, M.6
Pitha, P.M.7
White, M.F.8
Platanias, L.C.9
-
30
-
-
0029806856
-
TNF-α-induced phosphorylation and activation of cPLA2 are abrogated by an inhibitor of the p38 MAP kinase cascade in human neutrophils
-
Waterman, W.H., Molski, T.F., Huang, C.K., Adams, J.L. and Sha'afi, R.I. (1996) TNF-α-induced phosphorylation and activation of cPLA2 are abrogated by an inhibitor of the p38 MAP kinase cascade in human neutrophils. Biochem. J., 319, 17-20.
-
(1996)
Biochem. J.
, vol.319
, pp. 17-20
-
-
Waterman, W.H.1
Molski, T.F.2
Huang, C.K.3
Adams, J.L.4
Sha'afi, R.I.5
-
31
-
-
0030744123
-
Mapping of STAT3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of STAT1 and STAT3
-
Wen, Z. and Darnell, J.E. (1997) Mapping of STAT3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of STAT1 and STAT3. Nucleic Acids Res., 25, 2062-2067.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2062-2067
-
-
Wen, Z.1
Darnell, J.E.2
-
32
-
-
0029117304
-
Maximal activation of transcription by STAT1 and STAT3 requires both tyrosine and serine phosphorylation
-
Wen, Z., Zhong, Z. and Darnell, J.E. (1995) Maximal activation of transcription by STAT1 and STAT3 requires both tyrosine and serine phosphorylation. Cell, 82, 241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell, J.E.3
-
33
-
-
0032928614
-
Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
-
Widmann, C., Gibson, S., Jarpe, M.B. and Johnson, G.L. (1999) Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol. Rev., 79, 143-180.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
34
-
-
0030996469
-
Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation
-
Williams, B.R.G. (1997) Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation. Biochem. Soc. Trans., 25, 509-513.
-
(1997)
Biochem. Soc. Trans.
, vol.25
, pp. 509-513
-
-
Williams, B.R.G.1
-
35
-
-
0030974122
-
Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis
-
Wissing, D., Mouritzen, H., Egeblad, M., Poirier, G.G. and Jaattela, M. (1997) Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. Proc. Natl Acad. Sci. USA, 94, 5073-5077.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 5073-5077
-
-
Wissing, D.1
Mouritzen, H.2
Egeblad, M.3
Poirier, G.G.4
Jaattela, M.5
-
36
-
-
0031849783
-
Genomic features of human PKR: Alternative splicing and a polymorphic CGG repeat in the 5′-untranslated region
-
Xu, Z. and Williams, B.R.G. (1998) Genomic features of human PKR: alternative splicing and a polymorphic CGG repeat in the 5′-untranslated region. J. Interferon Cytokine Res., 18, 609-616.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 609-616
-
-
Xu, Z.1
Williams, B.R.G.2
-
37
-
-
0032515146
-
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells
-
Yamashita, H., Xu, J., Erwin, R.A., Farrar, W.L., Kirken, R.A. and Rui, H. (1998) Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells. J. Biol. Chem., 273, 30218-30224.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30218-30224
-
-
Yamashita, H.1
Xu, J.2
Erwin, R.A.3
Farrar, W.L.4
Kirken, R.A.5
Rui, H.6
-
38
-
-
0032510805
-
STAT3 complements defects in an IFN-resistant cell line: Evidence for an essential role for STAT3 in IFN signaling and biological activities
-
Yang, C.-H., Murti, A. and Pfeffer, L.M. (1998) STAT3 complements defects in an IFN-resistant cell line: evidence for an essential role for STAT3 in IFN signaling and biological activities. Proc. Natl Acad. Sci. USA, 95, 5568-5572.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 5568-5572
-
-
Yang, C.-H.1
Murti, A.2
Pfeffer, L.M.3
-
39
-
-
0032401780
-
Ser727-dependent recruitment of MCM5 by STAT1a in IFN-γ-induced transcriptional activation
-
Zhang, J.J., Zhao, Y., Chait, B.T., Lathem, W.W., Ritzi, M., Knippers, R. and Darnell, J.E. (1998) Ser727-dependent recruitment of MCM5 by STAT1a in IFN-γ-induced transcriptional activation. EMBO J., 17, 6963-6971.
-
(1998)
EMBO J.
, vol.17
, pp. 6963-6971
-
-
Zhang, J.J.1
Zhao, Y.2
Chait, B.T.3
Lathem, W.W.4
Ritzi, M.5
Knippers, R.6
Darnell, J.E.7
-
40
-
-
0030875862
-
STAT1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase
-
Zhu, X., Wen, Z., Xu, L.Z. and Darnell, J.E. (1997) STAT1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase. Mol. Cell. Biol., 17, 6618-6623.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6618-6623
-
-
Zhu, X.1
Wen, Z.2
Xu, L.Z.3
Darnell, J.E.4
|