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Volumn 66, Issue , 2012, Pages 177-196

A virological view of innate immune recognition

Author keywords

inflammasome; interferons; NOD like receptor; RIG I like receptor; Toll like receptor

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CD150 ANTIGEN; DNA DIRECTED RNA POLYMERASE III; DOUBLE STRANDED DNA; INFLAMMASOME; INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

EID: 84872259257     PISSN: 00664227     EISSN: 15453251     Source Type: Book Series    
DOI: 10.1146/annurev-micro-092611-150203     Document Type: Review
Times cited : (173)

References (111)
  • 1
    • 70349459734 scopus 로고    scopus 로고
    • RIG-Idependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
    • Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, Hornung V. 2009. RIG-Idependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat. Immunol. 10:1065-72
    • (2009) Nat. Immunol , vol.10 , pp. 1065-1072
    • Ablasser, A.1    Bauernfeind, F.2    Hartmann, G.3    Latz, E.4    Fitzgerald, K.A.5    Hornung, V.6
  • 2
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. 2006. Pathogen recognition and innate immunity. Cell 124:783-801
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 3
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413:732-38
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 4
    • 64049111768 scopus 로고    scopus 로고
    • TheNLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • Allen IC, ScullMA, MooreCB, Holl EK, McElvania-TeKippe E, et al. 2009. TheNLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 30:556-65
    • (2009) Immunity , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3    Holl, E.K.4    McElvania-Tekippe, E.5
  • 6
    • 0035202483 scopus 로고    scopus 로고
    • Mouse type i IFN-producing cells are immature APCs with plasmacytoid morphology
    • Asselin-Paturel C, Boonstra A, DalodM, Durand I, Yessaad N, et al. 2001. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2:1144-50
    • (2001) Nat. Immunol , vol.2 , pp. 1144-1150
    • Asselin-Paturel, C.1    Boonstra, A.2    Dalod, M.3    Durand, I.4    Yessaad, N.5
  • 7
    • 0015114139 scopus 로고
    • Expression of animal virus genomes
    • Baltimore D. 1971. Expression of animal virus genomes. Bacteriol. Rev. 35:235-41
    • (1971) Bacteriol. Rev , vol.35 , pp. 235-241
    • Baltimore, D.1
  • 8
    • 70350441863 scopus 로고    scopus 로고
    • Toll-like receptor 2 on inflammatory monocytes induces type i interferon in response to viral but not bacterial ligands
    • Barbalat R, Lau L, Locksley RM, Barton GM. 2009. Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands. Nat. Immunol. 10:1200-7
    • (2009) Nat. Immunol , vol.10 , pp. 1200-1207
    • Barbalat, R.1    Lau, L.2    Locksley, R.M.3    Barton, G.M.4
  • 9
    • 78650038649 scopus 로고    scopus 로고
    • Adenovirus membrane penetration activates the NLRP3 inflammasome
    • Barlan AU, Griffin TM, McGuire KA, Wiethoff CM. 2011. Adenovirus membrane penetration activates the NLRP3 inflammasome. J. Virol. 85:146-55
    • (2011) J. Virol , vol.85 , pp. 146-155
    • Barlan, A.U.1    Griffin, T.M.2    McGuire, K.A.3    Wiethoff, C.M.4
  • 10
    • 68849085894 scopus 로고    scopus 로고
    • A cell biological view of Toll-like receptor function: Regulation through compartmentalization
    • Barton GM, Kagan JC. 2009. A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat. Rev. Immunol. 9:535-42
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 535-542
    • Barton, G.M.1    Kagan, J.C.2
  • 11
    • 77957997708 scopus 로고    scopus 로고
    • Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing
    • Baum A, Sachidanandam R, Garcia-Sastre A. 2010. Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing. Proc. Natl. Acad. Sci. USA 107:16303-8
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 16303-16308
    • Baum, A.1    Sachidanandam, R.2    Garcia-Sastre, A.3
  • 12
    • 27644513772 scopus 로고    scopus 로고
    • Endocytosis ofHIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions
    • Beignon AS, McKenna K, SkoberneM, Manches O, Dasilva I, et al. 2005. Endocytosis ofHIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions. J. Clin. Invest. 115:3265-75
    • (2005) J. Clin. Invest , vol.115 , pp. 3265-3275
    • Beignon, A.S.1    McKenna, K.2    Skoberne, M.3    Manches, O.4    Dasilva, I.5
  • 13
    • 0036340341 scopus 로고    scopus 로고
    • Hemagglutinin protein of wild-type measles virus activates Toll-like receptor 2 signaling
    • Bieback K, Lien E, Klagge IM, Avota E, Schneider-Schaulies J, et al. 2002. Hemagglutinin protein of wild-type measles virus activates Toll-like receptor 2 signaling. J. Virol. 76:8729-36
    • (2002) J. Virol , vol.76 , pp. 8729-8736
    • Bieback, K.1    Lien, E.2    Klagge, I.M.3    Avota, E.4    Schneider-Schaulies, J.5
  • 14
    • 20344382957 scopus 로고    scopus 로고
    • Here a virus, there a virus, everywhere the same virus?
    • Breitbart M, Rohwer F. 2005. Here a virus, there a virus, everywhere the same virus? Trends Microbiol. 13:278-84
    • (2005) Trends Microbiol , vol.13 , pp. 278-284
    • Breitbart, M.1    Rohwer, F.2
  • 15
    • 60749136484 scopus 로고    scopus 로고
    • An orthogonal proteomicgenomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
    • B̈urckst ̈ummer T, Baumann C, Bl ̈uml S, Dixit E, D̈ urnberger G, et al. 2009. An orthogonal proteomicgenomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat. Immunol. 10:266-72
    • (2009) Nat. Immunol , vol.10 , pp. 266-272
    • B̈urcksẗummer, T.1    Baumann, C.2    Bl̈uml, S.3    Dixit, E.4    D̈urnberger, G.5
  • 16
    • 71749118530 scopus 로고    scopus 로고
    • Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses
    • Burke CW, Gardner CL, Steffan JJ, Ryman KD, Klimstra WB. 2009. Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses. Virology 395:121-32
    • (2009) Virology , vol.395 , pp. 121-132
    • Burke, C.W.1    Gardner, C.L.2    Steffan, J.J.3    Ryman, K.D.4    Klimstra, W.B.5
  • 17
    • 34548418137 scopus 로고    scopus 로고
    • Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins
    • Chang S, Dolganiuc A, Szabo G. 2007. Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins. J. Leukoc. Biol. 82:479-87
    • (2007) J. Leukoc. Biol , vol.82 , pp. 479-487
    • Chang, S.1    Dolganiuc, A.2    Szabo, G.3
  • 18
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type i interferons through the RIG-I pathway
    • Chiu YH, Macmillan JB, Chen ZJ. 2009. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 138:576-91
    • (2009) Cell , vol.138 , pp. 576-591
    • Chiu, Y.H.1    MacMillan, J.B.2    Chen, Z.J.3
  • 19
    • 0345505220 scopus 로고    scopus 로고
    • Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2
    • ComptonT, Kurt-Jones EA, Boehme KW, Belko J, Latz E, et al. 2003. Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J. Virol. 77:4588-96
    • (2003) J. Virol , vol.77 , pp. 4588-4596
    • Compton, T.1    Kurt-Jones, E.A.2    Boehme, K.W.3    Belko, J.4    Latz, E.5
  • 20
    • 78549284909 scopus 로고    scopus 로고
    • 2f-O methylation of the viral mRNA cap evades host restriction by IFIT family members
    • Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, et al. 2010. 2f-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature 468:452-56
    • (2010) Nature , vol.468 , pp. 452-456
    • Daffis, S.1    Szretter, K.J.2    Schriewer, J.3    Li, J.4    Youn, S.5
  • 21
    • 67650915065 scopus 로고    scopus 로고
    • Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome
    • Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, et al. 2009. Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog. 5:e1000480
    • (2009) PLoS Pathog , vol.5
    • Delaloye, J.1    Roger, T.2    Steiner-Tardivel, Q.G.3    Le Roy, D.4    Knaup Reymond, M.5
  • 22
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529-31
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis Sousa, E.C.5
  • 23
    • 33845579097 scopus 로고    scopus 로고
    • Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides
    • Diebold SS, Massacrier C, Akira S, Paturel C, Morel Y, Reis e Sousa C. 2006. Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides. Eur. J. Immunol. 36:3256-67
    • (2006) Eur. J. Immunol , vol.36 , pp. 3256-3267
    • Diebold, S.S.1    Massacrier, C.2    Akira, S.3    Paturel, C.4    Morel, Y.5    Reis Sousa, E.C.6
  • 25
    • 33644821166 scopus 로고    scopus 로고
    • Interactions between DNA viruses, ND10 and the DNA damage response
    • Everett RD. 2006. Interactions between DNA viruses, ND10 and the DNA damage response. Cell Microbiol. 8:365-74
    • (2006) Cell Microbiol , vol.8 , pp. 365-374
    • Everett, R.D.1
  • 26
    • 57349191215 scopus 로고    scopus 로고
    • The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
    • Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, et al. 2008. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 456:658-62
    • (2008) Nature , vol.456 , pp. 658-662
    • Ewald, S.E.1    Lee, B.L.2    Lau, L.3    Wickliffe, K.E.4    Shi, G.P.5
  • 27
    • 80055047268 scopus 로고    scopus 로고
    • Small noncoding RNA modulates Japanese encephalitis virus replication and translation in trans
    • Fan YH, Nadar M, Chen CC, Weng CC, Lin YT, Chang RY. 2011. Small noncoding RNA modulates Japanese encephalitis virus replication and translation in trans. Virol. J. 8:492
    • (2011) Virol. J , vol.8 , pp. 492
    • Fan, Y.H.1    Nadar, M.2    Chen, C.C.3    Weng, C.C.4    Lin, Y.T.5    Chang, R.Y.6
  • 28
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. 2009. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458:509-13
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 30
    • 20044379559 scopus 로고    scopus 로고
    • Control of antiviral defenses through hepatitisCvirus disruption of retinoic acid-inducible gene-I signaling
    • Foy E, Li K, Sumpter R Jr, Loo YM, Johnson CL, et al. 2005. Control of antiviral defenses through hepatitisCvirus disruption of retinoic acid-inducible gene-I signaling. Proc. Natl. Acad. Sci. USA102:2986-91
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2986-2991
    • Foy, E.1    Li, K.2    Sumpter Jr., R.3    Loo, Y.M.4    Johnson, C.L.5
  • 31
    • 48749085127 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases
    • GillietM, Cao W, Liu YJ. 2008. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat. Rev. Immunol. 8:594-606
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 594-606
    • Gilliet, M.1    Cao, W.2    Liu, Y.J.3
  • 32
    • 77649221014 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo
    • Gitlin L, Benoit L, Song C, Cella M, Gilfillan S, et al. 2010. Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. PLoS Pathog. 6:e1000734
    • (2010) PLoS Pathog , vol.6
    • Gitlin, L.1    Benoit, L.2    Song, C.3    Cella, M.4    Gilfillan, S.5
  • 33
    • 40249088259 scopus 로고    scopus 로고
    • The DNA sugar backbone 2, deoxyribose determines Toll-like receptor 9 activation
    • Haas T, Metzger J, Schmitz F, Heit A, Muller T, et al. 2008. The DNA sugar backbone 2, deoxyribose determines Toll-like receptor 9 activation. Immunity 28:315-23
    • (2008) Immunity , vol.28 , pp. 315-323
    • Haas, T.1    Metzger, J.2    Schmitz, F.3    Heit, A.4    Muller, T.5
  • 34
    • 33645142635 scopus 로고    scopus 로고
    • Viruses, endoplasmic reticulum stress, and interferon responses
    • He B. 2006. Viruses, endoplasmic reticulum stress, and interferon responses. Cell Death Differ. 13:393-403
    • (2006) Cell Death Differ , vol.13 , pp. 393-403
    • He, B.1
  • 36
    • 1542317578 scopus 로고    scopus 로고
    • Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8
    • Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, et al. 2004. Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303:1526-29
    • (2004) Science , vol.303 , pp. 1526-1529
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3    Ampenberger, F.4    Kirschning, C.5
  • 37
    • 3843103508 scopus 로고    scopus 로고
    • Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and-independent pathways
    • Hochrein H, Schlatter B, O'Keeffe M, Wagner C, Schmitz F, et al. 2004. Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and-independent pathways. Proc. Natl. Acad. Sci. USA 101:11416-21
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11416-11421
    • Hochrein, H.1    Schlatter, B.2    O'Keeffe, M.3    Wagner, C.4    Schmitz, F.5
  • 38
    • 38449120422 scopus 로고    scopus 로고
    • IFN-αβ-mediated inflammatory responses and antiviral defense in liver is TLR9-independent but MyD88-dependent during murine cytomegalovirus infection
    • Hokeness-Antonelli KL, Crane MJ, Dragoi AM, Chu WM, Salazar-Mather TP. 2007. IFN-αβ-mediated inflammatory responses and antiviral defense in liver is TLR9-independent but MyD88-dependent during murine cytomegalovirus infection. J. Immunol. 179:6176-83
    • (2007) J. Immunol , vol.179 , pp. 6176-6183
    • Hokeness-Antonelli, K.L.1    Crane, M.J.2    Dragoi, A.M.3    Chu, W.M.4    Salazar-Mather, T.P.5
  • 39
    • 33748475531 scopus 로고    scopus 로고
    • Type i interferon gene induction by the interferon regulatory factor family of transcription factors
    • Honda K, Takaoka A, Taniguchi T. 2006. Type I interferon gene induction by the interferon regulatory factor family of transcription factors. Immunity 25:349-60
    • (2006) Immunity , vol.25 , pp. 349-360
    • Honda, K.1    Takaoka, A.2    Taniguchi, T.3
  • 40
    • 63649133278 scopus 로고    scopus 로고
    • AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
    • Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, et al. 2009. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458:514-18
    • (2009) Nature , vol.458 , pp. 514-518
    • Hornung, V.1    Ablasser, A.2    Charrel-Dennis, M.3    Bauernfeind, F.4    Horvath, G.5
  • 42
    • 60549112774 scopus 로고    scopus 로고
    • Inflammasome recognition of influenza virus is essential for adaptive immune responses
    • Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. 2009. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J. Exp. Med. 206:79-87
    • (2009) J. Exp. Med , vol.206 , pp. 79-87
    • Ichinohe, T.1    Lee, H.K.2    Ogura, Y.3    Flavell, R.4    Iwasaki, A.5
  • 43
    • 77951295418 scopus 로고    scopus 로고
    • Influenza virus activates inflammasomes via its intracellular M2 ion channel
    • Ichinohe T, Pang IK, Iwasaki A. 2010. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nat. Immunol. 11:404-10
    • (2010) Nat. Immunol , vol.11 , pp. 404-410
    • Ichinohe, T.1    Pang, I.K.2    Iwasaki, A.3
  • 44
    • 38949093002 scopus 로고    scopus 로고
    • TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
    • Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, et al. 2008. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 451:725-29
    • (2008) Nature , vol.451 , pp. 725-729
    • Ishii, K.J.1    Kawagoe, T.2    Koyama, S.3    Matsui, K.4    Kumar, H.5
  • 46
    • 79960466171 scopus 로고    scopus 로고
    • Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry
    • Kane M, Case LK, Wang C, Yurkovetskiy L, Dikiy S, Golovkina TV. 2011. Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry. Immunity 35:135-45
    • (2011) Immunity , vol.35 , pp. 135-145
    • Kane, M.1    Case, L.K.2    Wang, C.3    Yurkovetskiy, L.4    Dikiy, S.5    Golovkina, T.V.6
  • 47
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
    • Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441:101-5
    • (2006) Nature , vol.441 , pp. 101-105
    • Kato, H.1    Takeuchi, O.2    Sato, S.3    Yoneyama, M.4    Yamamoto, M.5
  • 48
    • 27144440523 scopus 로고    scopus 로고
    • IPS-1, an adaptor triggering RIG-Iand Mda5-mediated type i interferon induction
    • Kawai T, Takahashi K, Sato S, Coban C, Kumar H, et al. 2005. IPS-1, an adaptor triggering RIG-Iand Mda5-mediated type I interferon induction. Nat. Immunol. 6:981-88
    • (2005) Nat. Immunol , vol.6 , pp. 981-988
    • Kawai, T.1    Takahashi, K.2    Sato, S.3    Coban, C.4    Kumar, H.5
  • 49
    • 0037407691 scopus 로고    scopus 로고
    • Activation with CpG - A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type i IFN synthesis in human plasmacytoid dendritic cells
    • Kerkmann M, Rothenfusser S, Hornung V, Towarowski A, Wagner M, et al. 2003. Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J. Immunol. 170:4465-74
    • (2003) J. Immunol , vol.170 , pp. 4465-4474
    • Kerkmann, M.1    Rothenfusser, S.2    Hornung, V.3    Towarowski, A.4    Wagner, M.5
  • 50
    • 79956061094 scopus 로고    scopus 로고
    • IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi sarcoma-associated herpesvirus infection
    • Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, et al. 2011. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi sarcoma-associated herpesvirus infection. Cell Host Microbe 9:363-75
    • (2011) Cell Host Microbe , vol.9 , pp. 363-375
    • Kerur, N.1    Veettil, M.V.2    Sharma-Walia, N.3    Bottero, V.4    Sadagopan, S.5
  • 51
    • 77957009390 scopus 로고    scopus 로고
    • Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells
    • Kim T, Pazhoor S, Bao M, Zhang Z, Hanabuchi S, et al. 2010. Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells. Proc. Natl. Acad. Sci. USA 107:15181-86
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 15181-15186
    • Kim, T.1    Pazhoor, S.2    Bao, M.3    Zhang, Z.4    Hanabuchi, S.5
  • 52
    • 0022447264 scopus 로고
    • Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferoninduced eIF-2αkinase
    • Kitajewski J, Schneider RJ, Safer B, Munemitsu SM, Samuel CE, et al. 1986. Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferoninduced eIF-2αkinase. Cell 45:195-200
    • (1986) Cell , vol.45 , pp. 195-200
    • Kitajewski, J.1    Schneider, R.J.2    Safer, B.3    Munemitsu, S.M.4    Samuel, C.E.5
  • 53
    • 0842342607 scopus 로고    scopus 로고
    • Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis
    • Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, et al. 2004. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc. Natl. Acad. Sci. USA 101:1315-20
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1315-1320
    • Kurt-Jones, E.A.1    Chan, M.2    Zhou, S.3    Wang, J.4    Reed, G.5
  • 54
    • 5944261457 scopus 로고    scopus 로고
    • Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
    • Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, et al. 2000. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1:398-401
    • (2000) Nat. Immunol , vol.1 , pp. 398-401
    • Kurt-Jones, E.A.1    Popova, L.2    Kwinn, L.3    Haynes, L.M.4    Jones, L.P.5
  • 55
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. 2007. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 315:1398-401
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 56
    • 58249084172 scopus 로고    scopus 로고
    • Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type i interferon receptor
    • Liu J, HuangFu WC, Kumar KG, Qian J, Casey JP, et al. 2009. Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor. Cell Host Microbe 5:72-83
    • (2009) Cell Host Microbe , vol.5 , pp. 72-83
    • Liu, J.1    Huang Fu, W.C.2    Kumar, K.G.3    Qian, J.4    Casey, J.P.5
  • 57
    • 37349052379 scopus 로고    scopus 로고
    • Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
    • Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, et al. 2008. Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J. Virol. 82:335-45
    • (2008) J. Virol , vol.82 , pp. 335-345
    • Loo, Y.M.1    Fornek, J.2    Crochet, N.3    Bajwa, G.4    Perwitasari, O.5
  • 58
    • 0037080186 scopus 로고    scopus 로고
    • IL-1βenhances CD40 ligandmediated cytokine secretion by human dendritic cells (DC): A mechanism for T cell-independent DC activation
    • Luft T, Jefford M, Luetjens P, Hochrein H, Masterman K-A, et al. 2002. IL-1βenhances CD40 ligandmediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation. J. Immunol. 168:713-22
    • (2002) J. Immunol , vol.168 , pp. 713-722
    • Luft, T.1    Jefford, M.2    Luetjens, P.3    Hochrein, H.4    Masterman, K.-A.5
  • 59
    • 0042123694 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells
    • Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. 2003. Toll-like receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells. J. Exp. Med. 198:513-20
    • (2003) J. Exp. Med , vol.198 , pp. 513-520
    • Lund, J.1    Sato, A.2    Akira, S.3    Medzhitov, R.4    Iwasaki, A.5
  • 60
    • 26944495290 scopus 로고    scopus 로고
    • Wrapping things up about virus RNA replication
    • Mackenzie J. 2005. Wrapping things up about virus RNA replication. Traffic 6:967-77
    • (2005) Traffic , vol.6 , pp. 967-977
    • MacKenzie, J.1
  • 61
    • 77955657565 scopus 로고    scopus 로고
    • Replication-independent activation of human plasmacytoid dendritic cells by the paramyxovirus SV5 requires TLR7 and autophagy pathways
    • Manuse MJ, Briggs CM, Parks GD. 2010. Replication-independent activation of human plasmacytoid dendritic cells by the paramyxovirus SV5 requires TLR7 and autophagy pathways. Virology 405:383-89
    • (2010) Virology , vol.405 , pp. 383-389
    • Manuse, M.J.1    Briggs, C.M.2    Parks, G.D.3
  • 63
    • 0025931571 scopus 로고
    • Adenovirus virus-associated RNA and translation control
    • Mathews MB, Shenk T. 1991. Adenovirus virus-associated RNA and translation control. J. Virol. 65:5657-62
    • (1991) J. Virol , vol.65 , pp. 5657-5662
    • Mathews, M.B.1    Shenk, T.2
  • 64
    • 27144440476 scopus 로고    scopus 로고
    • Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
    • Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, et al. 2005. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437:1167-72
    • (2005) Nature , vol.437 , pp. 1167-1172
    • Meylan, E.1    Curran, J.2    Hofmann, K.3    Moradpour, D.4    Binder, M.5
  • 65
    • 40449097257 scopus 로고    scopus 로고
    • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    • Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, et al. 2008. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452:103-7
    • (2008) Nature , vol.452 , pp. 103-107
    • Muruve, D.A.1    Petrilli, V.2    Zaiss, A.K.3    White, L.R.4    Clark, S.A.5
  • 66
    • 35448934984 scopus 로고    scopus 로고
    • Adeno-associated viruses can induce phosphorylation of eIF2α via PKR activation, which can be overcome by helper adenovirus type 5 virus-associated RNA
    • Nayak R, Pintel DJ. 2007. Adeno-associated viruses can induce phosphorylation of eIF2α via PKR activation, which can be overcome by helper adenovirus type 5 virus-associated RNA. J. Virol. 81:11908-16
    • (2007) J. Virol , vol.81 , pp. 11908-11916
    • Nayak, R.1    Pintel, D.J.2
  • 67
    • 79955961661 scopus 로고    scopus 로고
    • Varicella-zoster virus infection triggers formation of an interleukin-1β(IL-1β)-processing inflammasome complex
    • Nour AM, Reichelt M, Ku CC, Ho MY, Heineman TC, Arvin AM. 2011. Varicella-zoster virus infection triggers formation of an interleukin- 1β(IL-1β)-processing inflammasome complex. J. Biol. Chem. 286:17921-33
    • (2011) J. Biol. Chem , vol.286 , pp. 17921-17933
    • Nour, A.M.1    Reichelt, M.2    Ku, C.C.3    Ho, M.Y.4    Heineman, T.C.5    Arvin, A.M.6
  • 68
    • 56349114913 scopus 로고    scopus 로고
    • Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
    • Park B, Brinkmann MM, Spooner E, Lee CC, Kim YM, Ploegh HL. 2008. Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat. Immunol. 9:1407-14
    • (2008) Nat. Immunol , vol.9 , pp. 1407-1414
    • Park, B.1    Brinkmann, M.M.2    Spooner, E.3    Lee, C.C.4    Kim, Y.M.5    Ploegh, H.L.6
  • 70
    • 34548694962 scopus 로고    scopus 로고
    • Innate recognition of viruses
    • Pichlmair A, Reis e Sousa C. 2007. Innate recognition of viruses. Immunity 27:370-83
    • (2007) Immunity , vol.27 , pp. 370-383
    • Pichlmair, A.1    Reis Sousa, E.C.2
  • 71
    • 33750984771 scopus 로고    scopus 로고
    • RIG-I-mediated antiviral responses to single-stranded RNA bearing 5-phosphates
    • Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, et al. 2006. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5-phosphates. Science 314:997-1001
    • (2006) Science , vol.314 , pp. 997-1001
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3    Naslund, T.I.4    Liljestrom, P.5
  • 72
    • 70349728538 scopus 로고    scopus 로고
    • Activation of MDA5 requires higherorder RNA structures generated during virus infection
    • Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, et al. 2009. Activation of MDA5 requires higherorder RNA structures generated during virus infection. J. Virol. 83:10761-69
    • (2009) J. Virol , vol.83 , pp. 10761-10769
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3    Rehwinkel, J.4    Kato, H.5
  • 73
    • 57049096375 scopus 로고    scopus 로고
    • A highly structured, nucleaseresistant, noncoding RNAproduced by flaviviruses is required for pathogenicity
    • Pijlman GP, Funk A, Kondratieva N, Leung J, Torres S, et al. 2008. A highly structured, nucleaseresistant, noncoding RNAproduced by flaviviruses is required for pathogenicity. CellHostMicrobe 4:579-91
    • (2008) CellHostMicrobe , vol.4 , pp. 579-591
    • Pijlman, G.P.1    Funk, A.2    Kondratieva, N.3    Leung, J.4    Torres, S.5
  • 74
    • 33646932780 scopus 로고    scopus 로고
    • The M2 proton channels of influenza A and B viruses
    • Pinto LH, Lamb RA. 2006. The M2 proton channels of influenza A and B viruses. J. Biol. Chem. 281:8997-9000
    • (2006) J. Biol. Chem , vol.281 , pp. 8997-9000
    • Pinto, L.H.1    Lamb, R.A.2
  • 75
    • 74049126045 scopus 로고    scopus 로고
    • Recognition of RNA virus by RIG-I results in activation ofCARD9and inflammasome signaling for interleukin 1βproduction
    • Poeck H, Bscheider M, Gross O, Finger K, Roth S, et al. 2010. Recognition of RNA virus by RIG-I results in activation ofCARD9and inflammasome signaling for interleukin 1βproduction. Nat. Immunol. 11:63-69
    • (2010) Nat. Immunol , vol.11 , pp. 63-69
    • Poeck, H.1    Bscheider, M.2    Gross, O.3    Finger, K.4    Roth, S.5
  • 76
    • 82455212051 scopus 로고    scopus 로고
    • HIV-1 induces NALP3-inflammasome expression and interleukin-1β secretion in dendritic cells from healthy individuals but not from HIV-positive patients
    • Pontillo A, Silva LT, Oshiro TM, Finazzo C, Crovella S, Duarte AJ. 2012. HIV-1 induces NALP3-inflammasome expression and interleukin-1β secretion in dendritic cells from healthy individuals but not from HIV-positive patients. AIDS 26:11-18
    • (2012) AIDS , vol.26 , pp. 11-18
    • Pontillo, A.1    Silva, L.T.2    Oshiro, T.M.3    Finazzo, C.4    Crovella, S.5    Duarte, A.J.6
  • 77
    • 81255123292 scopus 로고    scopus 로고
    • Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by bothNLRP3 and multiple Toll-like receptors, which independently activate the inflammasome and NF-κB innate response pathways
    • Rahman MM, McFadden G. 2011. Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by bothNLRP3 and multiple Toll-like receptors, which independently activate the inflammasome and NF-κB innate response pathways. J. Virol. 85:12505-17
    • (2011) J. Virol , vol.85 , pp. 12505-12517
    • Rahman, M.M.1    McFadden, G.2
  • 78
    • 79955370281 scopus 로고    scopus 로고
    • The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection
    • Rajan JV, Rodriguez D, Miao EA, Aderem A. 2011. The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. J. Virol. 85:4167-72
    • (2011) J. Virol , vol.85 , pp. 4167-4172
    • Rajan, J.V.1    Rodriguez, D.2    Miao, E.A.3    Aderem, A.4
  • 79
    • 75749140581 scopus 로고    scopus 로고
    • RIG-I detects viral genomic RNA during negative-strand RNA virus infection
    • Rehwinkel J, Tan CP, Goubau D, Schulz O, Pichlmair A, et al. 2010. RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 140:397-408
    • (2010) Cell , vol.140 , pp. 397-408
    • Rehwinkel, J.1    Tan, C.P.2    Goubau, D.3    Schulz, O.4    Pichlmair, A.5
  • 80
    • 84859716889 scopus 로고    scopus 로고
    • TLR3deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice
    • ReinertLS, Harder L, Holm CK, IversenMB, HoranKA, et al. 2012. TLR3deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. J. Clin. Invest. 122:1368-76
    • (2012) J. Clin. Invest , vol.122 , pp. 1368-1376
    • Reinert, L.S.1    Harder, L.2    Holm, C.K.3    Iversen, M.B.4    Horan, K.A.5
  • 81
    • 60749104535 scopus 로고    scopus 로고
    • HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
    • Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, et al. 2009. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323:1057-60
    • (2009) Science , vol.323 , pp. 1057-1060
    • Roberts, T.L.1    Idris, A.2    Dunn, J.A.3    Kelly, G.M.4    Burnton, C.M.5
  • 83
    • 46249115827 scopus 로고    scopus 로고
    • Interferon-inducible antiviral effectors
    • Sadler AJ, Williams BR. 2008. Interferon-inducible antiviral effectors. Nat. Rev. Immunol. 8:559-68
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 559-568
    • Sadler, A.J.1    Williams, B.R.2
  • 84
    • 47949092573 scopus 로고    scopus 로고
    • Innate immunity induced by compositiondependent RIG-I recognition of hepatitis C virus RNA
    • SaitoT, OwenDM, Jiang F, Marcotrigiano J, GaleMJr. 2008. Innate immunity induced by compositiondependent RIG-I recognition of hepatitis C virus RNA. Nature 454:523-27
    • (2008) Nature , vol.454 , pp. 523-527
    • Saito, T.1    Owen, D.M.2    Jiang, F.3    Marcotrigiano, J.4    Gale, Jr.M.5
  • 85
    • 33748944149 scopus 로고    scopus 로고
    • EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type i IFN
    • SamantaM, Iwakiri D, Kanda T, Imaizumi T, Takada K. 2006. EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN. EMBO J. 25:4207-14
    • (2006) EMBO J , vol.25 , pp. 4207-4214
    • Samanta, M.1    Iwakiri, D.2    Kanda, T.3    Imaizumi, T.4    Takada, K.5
  • 86
    • 33751206873 scopus 로고    scopus 로고
    • Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells
    • Sato A, Linehan MM, Iwasaki A. 2006. Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells. Proc. Natl. Acad. Sci. USA 103:17343-48
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17343-17348
    • Sato, A.1    Linehan, M.M.2    Iwasaki, A.3
  • 87
    • 68049089651 scopus 로고    scopus 로고
    • Recognition of 5-triphosphate byRIG-I helicase requires short blunt double-strandedRNAas contained in panhandle of negativestrand virus
    • Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, et al. 2009. Recognition of 5-triphosphate byRIG-I helicase requires short blunt double-strandedRNAas contained in panhandle of negativestrand virus. Immunity 31:25-34
    • (2009) Immunity , vol.31 , pp. 25-34
    • Schlee, M.1    Roth, A.2    Hornung, V.3    Hagmann, C.A.4    Wimmenauer, V.5
  • 88
    • 67749133995 scopus 로고    scopus 로고
    • 5-Triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
    • Schmidt A, Schwerd T, Hamm W, Hellmuth JC, Cui S, et al. 2009. 5-Triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I. Proc. Natl. Acad. Sci. USA 106:12067-72
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 12067-12072
    • Schmidt, A.1    Schwerd, T.2    Hamm, W.3    Hellmuth, J.C.4    Cui, S.5
  • 89
    • 20044382430 scopus 로고    scopus 로고
    • Toll-like receptor 3 promotes cross-priming to virus-infected cells
    • Schulz O, Diebold SS, Chen M, N̈aslund TI, Nolte MA, et al. 2005. Toll-like receptor 3 promotes cross-priming to virus-infected cells. Nature 433:887-92
    • (2005) Nature , vol.433 , pp. 887-892
    • Schulz, O.1    Diebold, S.S.2    Chen, M.3    N̈aslund, T.I.4    Nolte, M.A.5
  • 90
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3
    • Seth RB, Sun L, Ea CK, Chen ZJ. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3. Cell 122:669-82
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 91
    • 49549100511 scopus 로고    scopus 로고
    • Trex1 prevents cell-intrinsic initiation of autoimmunity
    • Stetson DB, Ko JS, Heidmann T, Medzhitov R. 2008. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134:587-98
    • (2008) Cell , vol.134 , pp. 587-598
    • Stetson, D.B.1    Ko, J.S.2    Heidmann, T.3    Medzhitov, R.4
  • 92
    • 33746895106 scopus 로고    scopus 로고
    • Antiviral defense: Interferons and beyond
    • Stetson DB, Medzhitov R. 2006. Antiviral defense: interferons and beyond. J. Exp. Med. 203:1837-41
    • (2006) J. Exp. Med , vol.203 , pp. 1837-1841
    • Stetson, D.B.1    Medzhitov, R.2
  • 93
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • Stetson DB, Medzhitov R. 2006. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24:93-103
    • (2006) Immunity , vol.24 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 94
    • 34547743231 scopus 로고    scopus 로고
    • The inflammasome in pathogen recognition and inflammation
    • Sutterwala FS, OguraY, FlavellRA. 2007. The inflammasome in pathogen recognition and inflammation. J. Leukoc. Biol. 82:259-64
    • (2007) J. Leukoc. Biol , vol.82 , pp. 259-264
    • Sutterwala, F.S.1    Ogura, Y.2    Flavell, R.A.3
  • 96
    • 34547143110 scopus 로고    scopus 로고
    • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
    • Takaoka A. 2007. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448:501-5
    • (2007) Nature , vol.448 , pp. 501-505
    • Takaoka, A.1
  • 97
    • 64049096334 scopus 로고    scopus 로고
    • The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
    • Thomas PG, Dash P, Aldridge JR Jr, Ellebedy AH, Reynolds C, et al. 2009. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 30:566-75
    • (2009) Immunity , vol.30 , pp. 566-575
    • Thomas, P.G.1    Dash, P.2    Aldridge Jr., J.R.3    Ellebedy, A.H.4    Reynolds, C.5
  • 98
    • 79959634861 scopus 로고    scopus 로고
    • Pattern recognition receptors and the innate immune response to viral infection
    • Thompson MR, Kaminski JJ, Kurt-Jones EA, Fitzgerald KA. 2011. Pattern recognition receptors and the innate immune response to viral infection. Viruses 3:920-40
    • (2011) Viruses , vol.3 , pp. 920-940
    • Thompson, M.R.1    Kaminski, J.J.2    Kurt-Jones, E.A.3    Fitzgerald, K.A.4
  • 100
    • 47749109063 scopus 로고    scopus 로고
    • Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase
    • Wahid AM, Coventry VK, Conn GL. 2008. Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase. J. Biol. Chem. 283:17485-93
    • (2008) J. Biol. Chem , vol.283 , pp. 17485-17493
    • Wahid, A.M.1    Coventry, V.K.2    Conn, G.L.3
  • 101
    • 26444549006 scopus 로고    scopus 로고
    • Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages viaToll-like receptor 2
    • Wang JP, Kurt-Jones EA, Shin OS, ManchakMD, LevinMJ, Finberg RW. 2005. Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages viaToll-like receptor 2. J. Virol. 79:12658-66
    • (2005) J. Virol , vol.79 , pp. 12658-12666
    • Wang, J.P.1    Kurt-Jones, E.A.2    Shin, O.S.3    Manchak, M.D.4    Levin, M.J.5    Finberg, R.W.6
  • 102
    • 24944538819 scopus 로고    scopus 로고
    • VISA is an adapter protein required for virus-triggered IFN-βsignaling
    • Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. 2005. VISA is an adapter protein required for virus-triggered IFN-βsignaling. Mol. Cell 19:727-40
    • (2005) Mol. Cell , vol.19 , pp. 727-740
    • Xu, L.G.1    Wang, Y.Y.2    Han, K.J.3    Li, L.Y.4    Zhai, Z.5    Shu, H.B.6
  • 104
    • 77958114725 scopus 로고    scopus 로고
    • The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
    • Yan N, Regalado-Magdos AD, Stiggelbout B, Lee-Kirsch MA, Lieberman J. 2010. The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nat. Immunol. 11:1005-13
    • (2010) Nat. Immunol , vol.11 , pp. 1005-1013
    • Yan, N.1    Regalado-Magdos, A.D.2    Stiggelbout, B.3    Lee-Kirsch, M.A.4    Lieberman, J.5
  • 105
    • 77952566304 scopus 로고    scopus 로고
    • The cytosolic nucleic acid sensor LRRFIP1mediates the production of type i interferon via a β-catenin-dependent pathway
    • Yang P, An H, Liu X, Wen M, Zheng Y, et al. 2010. The cytosolic nucleic acid sensor LRRFIP1mediates the production of type I interferon via a β-catenin-dependent pathway. Nat. Immunol. 11:487-94
    • (2010) Nat. Immunol , vol.11 , pp. 487-494
    • Yang, P.1    An, H.2    Liu, X.3    Wen, M.4    Zheng, Y.5
  • 106
    • 44449125726 scopus 로고    scopus 로고
    • MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai virus defective interfering particles
    • Yount JS, Gitlin L, Moran TM, Ló pez CB. 2008. MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai virus defective interfering particles. J. Immunol. 180:4910-18
    • (2008) J. Immunol , vol.180 , pp. 4910-4918
    • Yount, J.S.1    Gitlin, L.2    Moran, T.M.3    Ló Pez, C.B.4
  • 107
    • 34548699323 scopus 로고    scopus 로고
    • TLR3 deficiency in patients with herpes simplex encephalitis
    • Zhang SY, Jouanguy E, Ugolini S, Smahi A, Elain G, et al. 2007. TLR3 deficiency in patients with herpes simplex encephalitis. Science 317:1522-27
    • (2007) Science , vol.317 , pp. 1522-1527
    • Zhang, S.Y.1    Jouanguy, E.2    Ugolini, S.3    Smahi, A.4    Elain, G.5
  • 108
    • 15844389172 scopus 로고    scopus 로고
    • MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection
    • Zhou S, Kurt-Jones EA, Mandell L, Cerny A, ChanM, et al. 2005. MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection. Eur. J. Immunol. 35:822-30
    • (2005) Eur. J. Immunol , vol.35 , pp. 822-830
    • Zhou, S.1    Kurt-Jones, E.A.2    Mandell, L.3    Cerny, A.4    Chan, M.5
  • 109
    • 68849103488 scopus 로고    scopus 로고
    • The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice
    • Zhu J, Huang X, Yang Y. 2009. The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice. J. Clin. Invest. 119:2388-98
    • (2009) J. Clin. Invest , vol.119 , pp. 2388-2398
    • Zhu, J.1    Huang, X.2    Yang, Y.3
  • 110
    • 33846232145 scopus 로고    scopus 로고
    • Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-β
    • Zhu J, Martinez J, Huang X, Yang Y. 2007. Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-β. Blood 109:619-25
    • (2007) Blood , vol.109 , pp. 619-625
    • Zhu, J.1    Martinez, J.2    Huang, X.3    Yang, Y.4
  • 111
    • 78751637122 scopus 로고    scopus 로고
    • Ribose 2f-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
    • Z̈ ust R, Cervantes-Barragan L, HabjanM, Maier R, Neuman BW, et al. 2011. Ribose 2f-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat. Immunol. 12:137-43
    • (2011) Nat. Immunol , vol.12 , pp. 137-143
    • Z̈ust, R.1    Cervantes-Barragan, L.2    Habjan, M.3    Maier, R.4    Neuman, B.W.5


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