The C proteins of human parainfluenza virus type 1 block IFN signaling by binding and retaining stat1 in perinuclear aggregates at the late endosome

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Schomacker, Henrick ^a   Hebner, Rebecca M ^a   Boonyaratanakornkit, Jim ^a   Surman, Sonja ^a   Amaro Carambot, Emerito ^a   Collins, Peter L ^a   Schmidt, Alexander C ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AMINO ACID; BETA INTERFERON; GAMMA INTERFERON; INTERFERON; INTERFERON RECEPTOR; PROTEIN C; RNA; SOMATOMEDIN B RECEPTOR; STAT1 PROTEIN; STAT2 PROTEIN; C PROTEIN, HUMAN PARAINFLUENZA VIRUS TYPE 1; STAT1 PROTEIN, HUMAN; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL AGGREGATION; CONTROLLED STUDY; ENDOSOME; GENE MUTATION; IMMUNE RESPONSE; IMMUNOPRECIPITATION; NONHUMAN; PARAINFLUENZA VIRUS 1; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA SYNTHESIS; VERO CELL; WILD TYPE; ANIMAL; CELL NUCLEUS; CERCOPITHECUS; DRUG ANTAGONISM; HUMAN; METABOLISM; PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; VIRUS REPLICATION; WESTERN BLOTTING;

HUMAN PARAINFLUENZA VIRUS 1;

ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; ENDOSOMES; HUMANS; IMMUNOPRECIPITATION; INTERFERONS; PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; VERO CELLS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84857088880     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028382     Document Type: Article

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