Emerging roles of the γ-secretase-notch axis in inflammation

Pharmacology and Therapeutics

Volumn 147, Issue , 2015, Pages 80-90

  Cheng, Yi Lin ^a,b   Choi, Yuri ^c   Sobey, Christopher G ^d   Arumugam, Thiruma V ^a,c   Jo, Dong Gyu ^c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c Sungkyunkwan University   (South Korea)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Inflammation; Inflammatory diseases; Notch; Stroke; Secretase

Indexed keywords

GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; HERMES ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MEMBRANE COFACTOR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; STAT PROTEIN; ENZYME INHIBITOR; SECRETASE;

ALZHEIMER DISEASE; ANTIINFLAMMATORY ACTIVITY; ASTHMA; ATHEROSCLEROSIS; BEHCET DISEASE; CEREBROVASCULAR ACCIDENT; CYTOKINE RELEASE; DRUG TARGETING; ENZYME INHIBITION; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFLAMMATORY DISEASE; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; RHEUMATOID ARTHRITIS; SEPSIS; SIGNAL TRANSDUCTION; SYSTEMIC SCLEROSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; INFLAMMATION; METABOLISM; PHYSIOLOGY; STROKE;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ENZYME INHIBITORS; HUMANS; INFLAMMATION; RECEPTORS, NOTCH; STROKE;

EID: 84922649714     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.11.005     Document Type: Review

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