APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Ghosal, Kaushik ^a   Stathopoulos, Andrea ^a   Pimplikar, Sanjay W ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BROXURIDINE; IBUPROFEN; NAPROXEN; APBB1 PROTEIN, MOUSE; NERVE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEAR PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; INTRACELLULAR MEMBRANE; LONG TERM CARE; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM INFLAMMATION; NEURAL STEM CELL; NEUROMODULATION; NEUROPATHOLOGY; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SPATIAL MEMORY; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; METABOLISM; NERVOUS SYSTEM DEVELOPMENT;

MUS; MUS MUSCULUS;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; IBUPROFEN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICE; MICE, TRANSGENIC; NAPROXEN; NERVE TISSUE PROTEINS; NEUROGENESIS; NUCLEAR PROTEINS;

EID: 77955637621     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011886     Document Type: Article

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