Cutting edge: Nicastrin and related components of γ-secretase generate a peptide epitope facilitating immune recognition of intracellular mycobacteria, through MHC class II-dependent priming of T cells

Journal of Immunology

Volumn 187, Issue 11, 2011, Pages 5495-5499

  Singh, Christopher R ^a   Bakhru, Pearl ^a   Khan, Arshad ^a   Li, Qing Bo ^b   Jagannath, Chinnaswamy ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; BCG VACCINE; EPITOPE; GAMMA SECRETASE; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NICASTRIN; PRESENILIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME INHIBITION; ENZYME LOCALIZATION; HYBRIDOMA; IMMUNIZATION; IMMUNOGENICITY; IN VITRO STUDY; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; PROTEOMICS; T LYMPHOCYTE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; ANTIGENS, BACTERIAL; BCG VACCINE; ENDOPEPTIDASES; EPITOPES, T-LYMPHOCYTE; FLUORESCENT ANTIBODY TECHNIQUE; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MYCOBACTERIUM BOVIS; PHAGOSOMES; PRESENILINS; PROTEOMICS; T-LYMPHOCYTES;

EID: 82755164896     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100521     Document Type: Article

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