메뉴 건너뛰기




Volumn 53, Issue 5, 2014, Pages 810-820

Increased notch pathway activation in Behçet's disease

Author keywords

Autoinflammatory conditions; Beh et's; Cell receptor ligand interaction; Cytokines and inflammatory mediators; Inflammation; Lymphocytes; MicroRNA; Molecular biology; Ophthalmic; Signalling and activation; T cells

Indexed keywords

CHLORAMBUCIL; CORTICOSTEROID DERIVATIVE; CYCLOSPORIN A; DLL 1 PROTEIN; DLL 4 PROTEIN; GAMMA INTERFERON; GAMMA SECRETASE INHIBITOR; INTERLEUKIN 17; JAGGED1; MICRORNA; MICRORNA 23B; N [N (3,5 DIFLUOROPHENACETYL) 1 ALANYL] S PHENYLGLYCINE TERT BUTYL ESTER; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; STAT3 PROTEIN; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG;

EID: 84898771879     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ket438     Document Type: Article
Times cited : (42)

References (44)
  • 1
    • 0029906621 scopus 로고    scopus 로고
    • The possible impact of uveitis in blindness: a literature survey
    • Suttorp-Schulten MS, Rothova A. The possible impact of uveitis in blindness: a literature survey. Br J Ophthalmol 1996;80:844-8.
    • (1996) Br J Ophthalmol , vol.80 , pp. 844-848
    • Suttorp-Schulten, M.S.1    Rothova, A.2
  • 2
    • 38549150450 scopus 로고    scopus 로고
    • Clinical features of Chinese patients with Behçet's disease
    • 312-8.e4
    • Yang P, Fang W, Meng Q et al. Clinical features of Chinese patients with Behçet's disease. Ophthalmology 2008; 115:312-8.e4.
    • (2008) Ophthalmology , vol.115
    • Yang, P.1    Fang, W.2    Meng, Q.3
  • 4
    • 0036351437 scopus 로고    scopus 로고
    • Cytokine profile in Behçet's disease patients. Relationship with disease activity
    • Hamzaoui K, Hamzaoui A, Guemira F et al. Cytokine profile in Behçet's disease patients. Relationship with disease activity. Scand J Rheumatol 2002;31:205-10.
    • (2002) Scand J Rheumatol , vol.31 , pp. 205-210
    • Hamzaoui, K.1    Hamzaoui, A.2    Guemira, F.3
  • 5
    • 79953719113 scopus 로고    scopus 로고
    • Expression of Th-17 and RORgammat mRNA in Behçet's disease
    • Hamzaoui K, Bouali E, Ghorbel I et al. Expression of Th-17 and RORgammat mRNA in Behçet's disease. Med Sci Monit 2011;17:CR227-34.
    • (2011) Med Sci Monit , vol.17
    • Hamzaoui, K.1    Bouali, E.2    Ghorbel, I.3
  • 6
    • 80855144043 scopus 로고    scopus 로고
    • Th17 cells in Behçet's disease: a new immunoregulatory axis
    • Hamzaoui K. Th17 cells in Behçet's disease: a new immunoregulatory axis. Clin Exp Rheumatol 2011;29: S71-6.
    • (2011) Clin Exp Rheumatol , vol.29
    • Hamzaoui, K.1
  • 7
    • 79960544098 scopus 로고    scopus 로고
    • Notch signaling regulates mouse and human Th17 differentiation
    • Keerthivasan S, Suleiman R, Lawlor R et al. Notch signaling regulates mouse and human Th17 differentiation. J Immunol 2011;187:692.
    • (2011) J Immunol , vol.187 , pp. 692
    • Keerthivasan, S.1    Suleiman, R.2    Lawlor, R.3
  • 9
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: unfolding the activation mechanism
    • Kopan R, Ilagan MXG. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009; 137:216-33.
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.G.2
  • 10
    • 1542317449 scopus 로고    scopus 로고
    • Notch regulation of lymphocyte development and function
    • Radtke F, Wilson A, Mancini SJC et al. Notch regulation of lymphocyte development and function. Nat Immunol 2004;5:247-53.
    • (2004) Nat Immunol , vol.5 , pp. 247-253
    • Radtke, F.1    Wilson, A.2    Mancini, S.J.C.3
  • 11
    • 8544262178 scopus 로고    scopus 로고
    • T cell acute lymphoblastic leukemia/ lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling
    • Pear WS, Aster JC. T cell acute lymphoblastic leukemia/ lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling. Curr Opin Hematol 2004;11: 426.
    • (2004) Curr Opin Hematol , vol.11 , pp. 426
    • Pear, W.S.1    Aster, J.C.2
  • 12
    • 22144492615 scopus 로고    scopus 로고
    • Inhibitors of g-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
    • Minter LM, Turley DM, Das P et al. Inhibitors of g-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nature immunology 2005;6:680-8.
    • (2005) Nature immunology , vol.6 , pp. 680-688
    • Minter, L.M.1    Turley, D.M.2    Das, P.3
  • 13
    • 34447642439 scopus 로고    scopus 로고
    • Notch directly regulates Gata3 expression during T helper 2 cell differentiation
    • Fang TC, Yashiro-Ohtani Y, Del Bianco C et al. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 2007;27:100-10.
    • (2007) Immunity , vol.27 , pp. 100-110
    • Fang, T.C.1    Yashiro-Ohtani, Y.2    Del Bianco, C.3
  • 14
    • 79955567838 scopus 로고    scopus 로고
    • Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis
    • Dees C, Zerr P, Tomcik M et al. Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis. Arthritis Rheum 2011; 63:1396-404.
    • (2011) Arthritis Rheum , vol.63 , pp. 1396-1404
    • Dees, C.1    Zerr, P.2    Tomcik, M.3
  • 15
    • 84863195085 scopus 로고    scopus 로고
    • Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis
    • Gao W, Sweeney C, Connolly M et al. Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis. Arthritis Rheum 2012;64:2104-13.
    • (2012) Arthritis Rheum , vol.64 , pp. 2104-2113
    • Gao, W.1    Sweeney, C.2    Connolly, M.3
  • 16
    • 76749106118 scopus 로고    scopus 로고
    • Expression analysis of Notch-related molecules in peripheral blood T helper cells of patients with rheumatoid arthritis
    • Jiao Z, Wang W, Guo M et al. Expression analysis of Notch-related molecules in peripheral blood T helper cells of patients with rheumatoid arthritis. Scand J Rheumatol 2010;39:26-32.
    • (2010) Scand J Rheumatol , vol.39 , pp. 26-32
    • Jiao, Z.1    Wang, W.2    Guo, M.3
  • 17
    • 79251563204 scopus 로고    scopus 로고
    • Blocking the NOTCH pathway inhibits vascular inflammation in largevessel vasculitis
    • Piggott K, Deng J, Warrington K et al. Blocking the NOTCH pathway inhibits vascular inflammation in largevessel vasculitis. Circulation 2011;123:309-18.
    • (2011) Circulation , vol.123 , pp. 309-318
    • Piggott, K.1    Deng, J.2    Warrington, K.3
  • 18
    • 80052685578 scopus 로고    scopus 로고
    • Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development
    • Bassil R, Zhu B, Lahoud Y et al. Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development. J Immunol 2011;187:2322-8.
    • (2011) J Immunol , vol.187 , pp. 2322-2328
    • Bassil, R.1    Zhu, B.2    Lahoud, Y.3
  • 19
    • 84855384313 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody
    • Ishida W, Fukuda K, Sakamoto S et al. Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody. Invest Ophthalmol Vis Sci 2011;52:8224-30.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 8224-8230
    • Ishida, W.1    Fukuda, K.2    Sakamoto, S.3
  • 20
    • 0025360899 scopus 로고
    • International Study Group for Behçet's Disease
    • Criteria for diagnosis of Behçet's disease.
    • Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease. Lancet 1990;335: 1078-80.
    • (1990) Lancet , vol.335 , pp. 1078-1080
  • 21
    • 58149120934 scopus 로고    scopus 로고
    • Notch signaling confers antigen-presenting cell functions on mast cells
    • Nakano N, Nishiyama C, Yagita H et al. Notch signaling confers antigen-presenting cell functions on mast cells. J Allergy Clin Immunol 2009;123:74-81.e1.
    • (2009) J Allergy Clin Immunol , vol.123
    • Nakano, N.1    Nishiyama, C.2    Yagita, H.3
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 48249149556 scopus 로고    scopus 로고
    • Upregulated IL-23 and IL-17 in Behçet patients with active uveitis
    • Chi W, Zhu X, Yang P et al. Upregulated IL-23 and IL-17 in Behçet patients with active uveitis. Invest Ophthalmol Vis Sci 2008;49:3058-64.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 3058-3064
    • Chi, W.1    Zhu, X.2    Yang, P.3
  • 24
    • 77951884078 scopus 로고    scopus 로고
    • Cross-talk between miRNA and Notch signaling pathways in tumor development and progression
    • Wang Z, Li Y, Kong D et al. Cross-talk between miRNA and Notch signaling pathways in tumor development and progression. Cancer Lett 2010;292:141-8.
    • (2010) Cancer Lett , vol.292 , pp. 141-148
    • Wang, Z.1    Li, Y.2    Kong, D.3
  • 25
    • 77953920780 scopus 로고    scopus 로고
    • MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells
    • Pang RT, Leung CO, Ye TM et al. MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. Carcinogenesis 2010;31:1037-44.
    • (2010) Carcinogenesis , vol.31 , pp. 1037-1044
    • Pang, R.T.1    Leung, C.O.2    Ye, T.M.3
  • 26
    • 39049191809 scopus 로고    scopus 로고
    • Exploration of human miRNA target genes in neuronal differentiation
    • Fukuda Y, Kawasaki H, Taira K. Exploration of human miRNA target genes in neuronal differentiation. Nucleic Acids Symp Ser 2005;341-2.
    • (2005) Nucleic Acids Symp Ser , pp. 341-342
    • Fukuda, Y.1    Kawasaki, H.2    Taira, K.3
  • 27
    • 84862819758 scopus 로고    scopus 로고
    • MicroRNA-23b promotes tolerogenic properties of dendritic cells in vitro through inhibiting Notch1/NF-kB signalling pathways
    • Zheng J, Jiang HY, Li J et al. MicroRNA-23b promotes tolerogenic properties of dendritic cells in vitro through inhibiting Notch1/NF-kB signalling pathways. Allergy 2012;67:362-70.
    • (2012) Allergy , vol.67 , pp. 362-370
    • Zheng, J.1    Jiang, H.Y.2    Li, J.3
  • 28
    • 67651098994 scopus 로고    scopus 로고
    • MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation
    • Hashimi ST, Fulcher JA, Chang MH et al. MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood 2009;114:404-14.
    • (2009) Blood , vol.114 , pp. 404-414
    • Hashimi, S.T.1    Fulcher, J.A.2    Chang, M.H.3
  • 29
    • 0041331708 scopus 로고    scopus 로고
    • TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells
    • Palaga T, Miele L, Golde TE et al. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J Immunol 2003;171: 3019-24.
    • (2003) J Immunol , vol.171 , pp. 3019-3024
    • Palaga, T.1    Miele, L.2    Golde, T.E.3
  • 30
    • 84866466714 scopus 로고    scopus 로고
    • Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves
    • Zeng Q, Jin C, Ao L et al. Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves. Circulation 2012;126:S222-30.
    • (2012) Circulation , vol.126
    • Zeng, Q.1    Jin, C.2    Ao, L.3
  • 31
    • 79953127124 scopus 로고    scopus 로고
    • Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation
    • Bansal K, Balaji KN. Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation. J Biol Chem 2011;286:5823-35.
    • (2011) J Biol Chem , vol.286 , pp. 5823-5835
    • Bansal, K.1    Balaji, K.N.2
  • 32
    • 39549115001 scopus 로고    scopus 로고
    • Association of reduced heme oxygenase-1 with excessive Toll-like receptor 4 expression in peripheral blood mononuclear cells in Behçet's disease
    • Kirino Y, Takeno M, Watanabe R et al. Association of reduced heme oxygenase-1 with excessive Toll-like receptor 4 expression in peripheral blood mononuclear cells in Behçet's disease. Arthritis Res Ther 2008;10:R16.
    • (2008) Arthritis Res Ther , vol.10
    • Kirino, Y.1    Takeno, M.2    Watanabe, R.3
  • 33
    • 84856791579 scopus 로고    scopus 로고
    • NOD2 is highly expressed in Behçet disease with pulmonary manifestations
    • Hamzaoui K, Abid H, Berraies A et al. NOD2 is highly expressed in Behçet disease with pulmonary manifestations. J Inflamm 2012;9:3.
    • (2012) J Inflamm , vol.9 , pp. 3
    • Hamzaoui, K.1    Abid, H.2    Berraies, A.3
  • 34
    • 79953297480 scopus 로고    scopus 로고
    • RORC and Foxp3 axis in cerebrospinal fluid of patients with neuro-Behçet's disease
    • Hamzaoui K, Borhani Haghighi A, Ghorbel IB et al. RORC and Foxp3 axis in cerebrospinal fluid of patients with neuro-Behçet's disease. J Neuroimmunol 2011;233: 249-53.
    • (2011) J Neuroimmunol , vol.233 , pp. 249-253
    • Hamzaoui, K.1    Borhani Haghighi, A.2    Ghorbel, I.B.3
  • 35
    • 65649149442 scopus 로고    scopus 로고
    • g-Secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses
    • Kang JH, Kim BS, Uhm TG et al. g-Secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses. Am J Respir Crit Care Med 2009; 179:875-82.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 875-882
    • Kang, J.H.1    Kim, B.S.2    Uhm, T.G.3
  • 36
    • 34247122412 scopus 로고    scopus 로고
    • Stat3 and Stat4 direct development of IL-17-secreting Th cells
    • Mathur AN, Chang HC, Zisoulis DG et al. Stat3 and Stat4 direct development of IL-17-secreting Th cells. J Immunol 2007;178:4901.
    • (2007) J Immunol , vol.178 , pp. 4901
    • Mathur, A.N.1    Chang, H.C.2    Zisoulis, D.G.3
  • 37
    • 2942709503 scopus 로고    scopus 로고
    • Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
    • Kamakura S, Oishi K, Yoshimatsu T et al. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol 2004;6:547-54.
    • (2004) Nat Cell Biol , vol.6 , pp. 547-554
    • Kamakura, S.1    Oishi, K.2    Yoshimatsu, T.3
  • 38
    • 79960405025 scopus 로고    scopus 로고
    • SPARC stimulates neuronal differentiation of medulloblastoma cells via the Notch1/STAT3 pathway
    • Bhoopathi P, Chetty C, Dontula R et al. SPARC stimulates neuronal differentiation of medulloblastoma cells via the Notch1/STAT3 pathway. Cancer Res 2011;71: 4908.
    • (2011) Cancer Res , vol.71 , pp. 4908
    • Bhoopathi, P.1    Chetty, C.2    Dontula, R.3
  • 39
    • 70449716915 scopus 로고    scopus 로고
    • MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
    • Du C, Liu C, Kang J et al. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol 2009;10: 1252-9.
    • (2009) Nat Immunol , vol.10 , pp. 1252-1259
    • Du, C.1    Liu, C.2    Kang, J.3
  • 40
    • 77956632634 scopus 로고    scopus 로고
    • Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
    • Lu LF, Boldin MP, Chaudhry A et al. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 2010;142:914-29.
    • (2010) Cell , vol.142 , pp. 914-929
    • Lu, L.F.1    Boldin, M.P.2    Chaudhry, A.3
  • 41
    • 77958495102 scopus 로고    scopus 로고
    • MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
    • O'Connell RM, Kahn D, Gibson WSJ et al. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 2010;33: 607-19.
    • (2010) Immunity , vol.33 , pp. 607-619
    • O'Connell, R.M.1    Kahn, D.2    Gibson, W.S.J.3
  • 42
    • 49149117727 scopus 로고    scopus 로고
    • Decreased percentages of regulatory T cells in peripheral blood of patients with Behçet's disease before ocular attack: a possible predictive marker of ocular attack
    • Nanke Y, Kotake S, Goto M et al. Decreased percentages of regulatory T cells in peripheral blood of patients with Behçet's disease before ocular attack: a possible predictive marker of ocular attack. Mod Rheumatol 2008;18:354-8.
    • (2008) Mod Rheumatol , vol.18 , pp. 354-358
    • Nanke, Y.1    Kotake, S.2    Goto, M.3
  • 43
    • 84863686039 scopus 로고    scopus 로고
    • The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha
    • Zhu S, Pan W, Song X et al. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha. Nat Med 2012; 18:1077-86.
    • (2012) Nat Med , vol.18 , pp. 1077-1086
    • Zhu, S.1    Pan, W.2    Song, X.3
  • 44
    • 33746653813 scopus 로고    scopus 로고
    • Vascular involvement in Behçet's disease: a retrospective analysis of 2319 cases
    • Sarica-Kucukoglu R, Akdag-Kose A, Kayabal IM et al. Vascular involvement in Behçet's disease: a retrospective analysis of 2319 cases. Int J Dermatol 2006;45:919-21.
    • (2006) Int J Dermatol , vol.45 , pp. 919-921
    • Sarica-Kucukoglu, R.1    Akdag-Kose, A.2    Kayabal, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.