Ligand-induced signaling in the absence of furin processing of Notch1

Developmental Biology

Volumn 229, Issue 2, 2001, Pages 494-502

  Bush, Gay ^a   DiSibio, Guy ^a,b   Miyamoto, Alison ^a   Denault, Jean Bernard ^c   Leduc, Richard ^c   Weinmaster, Gerry ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Furin; Notch; Proteolytic processing; Signaling; Transmembrane receptor

Indexed keywords

CELL SURFACE RECEPTOR; DNA; ENZYME; ENZYME INHIBITOR; FURIN; POLYPEPTIDE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; DNA SEQUENCE; GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

EID: 0035862738     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9992     Document Type: Article

References (24)

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2. Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch
3. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane
4. Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues
5. Roles for proteolysis and trafficking in notch maturation and signal transduction
6. Presenilins, processing of beta-amyloid precursor protein, and notch signaling
7. Notch signaling in vertebrate development and disease
8. Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
9. Delta-1 activation of notch-1 signaling results in HES-1 transactivation
10. The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
11. A subset of notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex
12. Jagged: A mammalian ligand that activates Notch1
13. The Notch1 receptor is cleaved constitutively by a furin-like convertase
14. pEF-BOS, a powerful mammalian expression vector
15. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
16. Calcium depletion dissociates and activates heterodimeric notch receptors
17. Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch
18. Nuclear Notch1 signaling and the regulation of dendritic development
19. Evidence for a novel Notch pathway required for muscle precursor selection in Drosophila
20. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
21. Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless
22. The ins and outs of notch signaling
23. Notch signal transduction: A real rip and more
24. An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila