Current state-of-the-art of nontargeted metabolomics based on liquid chromatography-mass spectrometry with special emphasis in clinical applications

Journal of Chromatography A

Volumn 1374, Issue , 2014, Pages 1-13

  Yin, Peiyuan ^a   Xu, Guowang ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

LC MS; Metabolic profiling; Metabolite coverage; Metabolomics; Pseudo targeted method

Indexed keywords

BIOMOLECULES; DATA HANDLING; MASS SPECTROMETRY; METABOLISM; METABOLITES;

DEVELOPMENT AND APPLICATIONS; HIGH RESOLUTION MASS SPECTROMETRY; LC-MS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; METABOLIC PROFILING; METABOLOMICS; PSEUDO-TARGETED METHOD; STRUCTURAL IDENTIFICATION;

LIQUID CHROMATOGRAPHY;

DERIVATIZATION; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; HYDROPHILICITY; INFORMATION PROCESSING; ION EXCHANGE CHROMATOGRAPHY; ISOTOPE LABELING; LIQUID CHROMATOGRAPH; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEASUREMENT REPEATABILITY; METABOLOMICS; MOLECULAR WEIGHT; MULTIVARIATE ANALYSIS; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; REVIEW; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; SOLID PHASE EXTRACTION; SOLID PHASE MICROEXTRACTION; TWO DIMENSIONAL LIQUID CHROMATOGRAPHY SYSTEM; UNIVARIATE ANALYSIS; DEVICES; PROCEDURES;

ISOTOPE;

CHROMATOGRAPHY, LIQUID; ISOTOPES; MASS SPECTROMETRY; METABOLOMICS;

EID: 84916206432     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.11.050     Document Type: Review

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