메뉴 건너뛰기




Volumn 6, Issue 6, 2014, Pages 761-771

Matrix effects in metabolite quantification for mist assessment: The impact of phospholipid removal and hplc column particle size

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; AMFEBUTAMONE; AMITRIPTYLINE; ANDROSTANOLONE; CLOPIDOGREL; CLOPIDOGREL CARBOXYLIC ACID; CLOZAPINE; DRUG METABOLITE; FENTANYL; FEXOFENADINE; MIDAZOLAM; NORCLOZAPINE; NORFENTANYL; NORTRIPTYLINE; PALIPERIDONE; PHOSPHOLIPID; QUETIAPINE; RADAFAXINE; RISPERIDONE; TERFENADINE; TESTOSTERONE; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 84898743291     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.330     Document Type: Article
Times cited : (8)

References (18)
  • 3
    • 78649231563 scopus 로고    scopus 로고
    • Challenges and solutions to metabolites in safety testing: Impact of the International Conference on Harmonization M3(R2) guidance
    • Yu H, Bischoff D, Tweedie D. Challenges and solutions to metabolites in safety testing: impact of the International Conference on Harmonization M3(R2) guidance. Expert Opin. Drug Metab. Toxixol. 6(12), 1539-1549 (2010).
    • (2010) Expert Opin. Drug Metab. Toxixol. , vol.6 , Issue.12 , pp. 1539-1549
    • Yu, H.1    Bischoff, D.2    Tweedie, D.3
  • 4
    • 62249135160 scopus 로고    scopus 로고
    • Approaches to the assessment of stable and chemically reactive drug metabolites in early clinical trials
    • Baillie TA. Approaches to the assessment of stable and chemically reactive drug metabolites in early clinical trials. Chem. Res. Toxicol. 22(2), 263-266 (2009).
    • (2009) Chem. Res. Toxicol. , vol.22 , Issue.2 , pp. 263-266
    • Baillie, T.A.1
  • 5
    • 78650423579 scopus 로고    scopus 로고
    • Determination of exposure multiples of human metabolites for MIST assessment in preclinical safety species without using reference standards or radiolabeled compounds
    • Ma S, Li Z, Lee KJ, Chowdhury SK. Determination of exposure multiples of human metabolites for MIST assessment in preclinical safety species without using reference standards or radiolabeled compounds. Chem. Res. Toxicol. 23(12), 1871-1873 (2010).
    • (2010) Chem. Res. Toxicol. , vol.23 , Issue.12 , pp. 1871-1873
    • Ma, S.1    Li, Z.2    Lee, K.J.3    Chowdhury, S.K.4
  • 6
    • 84855272978 scopus 로고    scopus 로고
    • Evaluation of relative LC-MS response of metabolites to parent drug in LC/nanospray ionization mass spectrometry: Potential implications in MIST assessment
    • Schadt S, Chen L-Z, Bischoff D. Evaluation of relative LC-MS response of metabolites to parent drug in LC/nanospray ionization mass spectrometry: potential implications in MIST assessment. J. Mass Spectrom. 46(12), 1282-1287 (2011).
    • (2011) J. Mass Spectrom. , vol.46 , Issue.12 , pp. 1282-1287
    • Schadt, S.1    Chen, L.-Z.2    Bischoff, D.3
  • 7
    • 78649628659 scopus 로고    scopus 로고
    • A simple liquid chromatography-tandem mass spectrometry method to determine relative plasma exposures of drug metabolites across species for metabolite safety assessments
    • Gao H, Deng S, Obach RS. A simple liquid chromatography-tandem mass spectrometry method to determine relative plasma exposures of drug metabolites across species for metabolite safety assessments. Drug Metab. Dispos. 38(12), 2147-2156 (2010).
    • (2010) Drug Metab. Dispos. , vol.38 , Issue.12 , pp. 2147-2156
    • Gao, H.1    Deng, S.2    Obach, R.S.3
  • 8
    • 34249721558 scopus 로고    scopus 로고
    • E, Wagrowski-Diehl DM, Lu Z, Mazzeo JR. Systematic and comprehensive strategy for reducing matrix effects in LC-MS/MS analyses
    • Chambers
    • Chambers E, Wagrowski-Diehl DM, Lu Z, Mazzeo JR. Systematic and comprehensive strategy for reducing matrix effects in LC-MS/MS analyses. J. Chromatogr. B 852(1-2), 22-34 (2007).
    • (2007) J. Chromatogr. B , vol.852 , Issue.1-2 , pp. 22-34
  • 9
    • 79951750007 scopus 로고    scopus 로고
    • Elimination of LC-MS/MS matrix effect due to phospholipids using specific solid-phase extraction elution conditions
    • Lahaie M, Mess J-N, Furtado M, Garofolo F. Elimination of LC-MS/MS matrix effect due to phospholipids using specific solid-phase extraction elution conditions. Bioanalysis 2(6), 1011-1021 (2010).
    • (2010) Bioanalysis , vol.2 , Issue.6 , pp. 1011-1021
    • Lahaie, M.1    Mess, J.-N.2    Furtado, M.3    Garofolo, F.4
  • 10
    • 0037663202 scopus 로고    scopus 로고
    • Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC?MS/MS
    • Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC?MS/MS. Anal. Chem. 75(13), 3019-3030 (2003).
    • (2003) Anal. Chem. , vol.75 , Issue.13 , pp. 3019-3030
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chavez-Eng, C.M.3
  • 11
    • 84859960927 scopus 로고    scopus 로고
    • Efficacy of plasma phospholipid removal during sample preparation and subsequent retention under typical UHPLC conditions
    • Neville D, Houghton R, Garrett S. Efficacy of plasma phospholipid removal during sample preparation and subsequent retention under typical UHPLC conditions. Bioanalysis 4(7), 795-807 (2012).
    • (2012) Bioanalysis , vol.4 , Issue.7 , pp. 795-807
    • Neville, D.1    Houghton, R.2    Garrett, S.3
  • 12
    • 34247843033 scopus 로고    scopus 로고
    • Key elements of bioanalytical method validation for small molecules
    • Bansal S, DeStefano A. Key elements of bioanalytical method validation for small molecules. AAPS J. 9(1), E109-E114 (2007).
    • (2007) AAPS J. , vol.9 , Issue.1
    • Bansal, S.1    Destefano, A.2
  • 13
    • 84898735034 scopus 로고    scopus 로고
    • ChemAxon. Chemicalize.
    • ChemAxon. Chemicalize. www.chemicalize.org
  • 14
    • 67650357558 scopus 로고    scopus 로고
    • Phospholipids in liquid chromatography-mass spectrometry bioanalysis: Comparison of three tandem mass spectrometric techniques for monitoring plasma phospholipids, the effect of mobile phase composition on phospholipids elution and the association of phospholipids with matrix effects
    • Xia Y-Q, Jemal M. Phospholipids in liquid chromatography-mass spectrometry bioanalysis: comparison of three tandem mass spectrometric techniques for monitoring plasma phospholipids, the effect of mobile phase composition on phospholipids elution and the association of phospholipids with matrix effects. Rapid Commun. Mass Spectrom. 23(14), 2125-2138 (2009).
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.14 , pp. 2125-2138
    • Xia, Y.-Q.1    Jemal, M.2
  • 15
    • 33645224920 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: Examining lipid matrix ionization effects in plasma
    • Little JL, Wempe MF, Buchanan CM. Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: examining lipid matrix ionization effects in plasma. J. Chromatogr. B 833(2), 219-230 (2006).
    • (2006) J. Chromatogr. B , vol.833 , Issue.2 , pp. 219-230
    • Little, J.L.1    Wempe, M.F.2    Buchanan, C.M.3
  • 16
    • 0032566565 scopus 로고    scopus 로고
    • Development of high-performance liquid chromatography-tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: A case of lack of specificity due to the presence of metabolites
    • Matuszewski BK, Chavez CM, Constanzer ML. Development of high-performance liquid chromatography-tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: a case of lack of specificity due to the presence of metabolites. J. Chromtogr. B 716, 195-208 (1998).
    • (1998) J. Chromtogr. B , vol.716 , pp. 195-208
    • Matuszewski, B.K.1    Chavez, C.M.2    Constanzer, M.L.3
  • 17
    • 27944457524 scopus 로고    scopus 로고
    • Rapid detection and characterization of minor reactive metabolites using stable-isotope trapping in combination with tandem mass spectrometry
    • Yan Z, Maher N, Torres R, Caldwell GW, Huebert N. Rapid detection and characterization of minor reactive metabolites using stable-isotope trapping in combination with tandem mass spectrometry. Rapid Commun. Mass Spectrom. 19(22), 3322-3330 (2005).
    • (2005) Rapid Commun. Mass Spectrom. , vol.19 , Issue.22 , pp. 3322-3330
    • Yan, Z.1    Maher, N.2    Torres, R.3    Caldwell, G.W.4    Huebert, N.5
  • 18
    • 84867538472 scopus 로고    scopus 로고
    • High-resolution isotope-dilution mass spectrometry using metabolism of isotope-labeled compounds: Application to drug metabolites
    • Vrbanac JJ, Hilgers A, Dubnicka T, Shilliday FB, Humphries D, Hayes RN. High-resolution isotope-dilution mass spectrometry using metabolism of isotope-labeled compounds: application to drug metabolites. Rapid Commun. Mass Spectrom. 26(22), 2569-2576 (2012).
    • (2012) Rapid Commun. Mass Spectrom. , vol.26 , Issue.22 , pp. 2569-2576
    • Vrbanac, J.J.1    Hilgers, A.2    Dubnicka, T.3    Shilliday, F.B.4    Humphries, D.5    Hayes, R.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.