New sample preparation approach for mass spectrometry-based profiling of plasma results in improved coverage of metabolome

Journal of Chromatography A

Volumn 1300, Issue , 2013, Pages 217-226

  Yang, Yanhui ^a   Cruickshank, Charmion ^a   Armstrong, Michael ^a   Mahaffey, Spencer ^b   Reisdorph, Rick ^a   Reisdorph, Nichole ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Liquid chromatography; Mass spectrometry; Metabolomics; Plasma; Profiling

Indexed keywords

ENDOGENOUS METABOLITES; INTERNAL STANDARDS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; METABOLOMICS; PROFILING; QUALITATIVE ANALYSIS; SAMPLE PREPARATION; SOLID PHASE EXTRACTION METHOD;

BIOMOLECULES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; PHOSPHOLIPIDS; PLASMAS;

METABOLITES;

ALANINE; ARGININE; CERAMIDE; CREATINE; CREATININE; GLUCOSE; METHANOL; OLEIC ACID; ORNITHINE; TESTOSTERONE;

ARTICLE; CONTROLLED STUDY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; METABOLITE; METABOLOME; PRECIPITATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SOLID PHASE EXTRACTION;

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLOMICS; PLASMA; PROFILING;

BLOOD CHEMICAL ANALYSIS; CHROMATOGRAPHY, REVERSE-PHASE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; LIQUID-LIQUID EXTRACTION; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; METHANOL; METHYL ETHERS; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION;

EID: 84879890387     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.04.030     Document Type: Article

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