-
1
-
-
0032694577
-
'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson, J.K., Lindon, J.C. & Holmes, E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29, 1181-1189 (1999).
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
2
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function
-
DOI 10.1038/nrd728
-
Nicholson, J.K., Connelly, J., Lindon, J.C. & Holmes, E. Metabonomics: a platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 1, 153-161 (2002). (Pubitemid 41646523)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.2
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
Holmes, E.4
-
3
-
-
0036007687
-
Metabolomics - The link between genotypes and phenotypes
-
DOI 10.1023/A:1013713905833
-
Fiehn, O. Metabolomics - the link between genotypes and phenotypes. Plant Mol. Biol. 48, 155-171 (2002). (Pubitemid 34128498)
-
(2002)
Plant Molecular Biology
, vol.48
, Issue.1-2
, pp. 155-171
-
-
Fiehn, O.1
-
4
-
-
54549091125
-
Systems biology: Metabonomics
-
Nicholson, J.K. & Lindon, J.C. Systems biology: metabonomics. Nature 455, 1054-1056 (2008).
-
(2008)
Nature
, vol.455
, pp. 1054-1056
-
-
Nicholson, J.K.1
Lindon, J.C.2
-
5
-
-
50149086997
-
Applications of metabolomics in drug discovery and development
-
Wishart, D.S. Applications of metabolomics in drug discovery and development. Drugs R D 9, 307-322 (2008).
-
(2008)
Drugs R D
, vol.9
, pp. 307-322
-
-
Wishart, D.S.1
-
6
-
-
41949108590
-
Metabolic profiling as a tool for understanding mechanisms of toxicity
-
Clarke, C.J. & Haselden, J.N. Metabolic profiling as a tool for understanding mechanisms of toxicity. Toxicol. Pathol. 36, 140-147 (2008).
-
(2008)
Toxicol. Pathol.
, vol.36
, pp. 140-147
-
-
Clarke, C.J.1
Haselden, J.N.2
-
7
-
-
52049108458
-
Metabolomics-based methods for early disease diagnostics
-
Gowda, G.A. et al. Metabolomics-based methods for early disease diagnostics. Expert Rev. Mol. Diagn. 8, 617-633 (2008).
-
(2008)
Expert Rev. Mol. Diagn.
, vol.8
, pp. 617-633
-
-
Gowda, G.A.1
-
8
-
-
17444404226
-
High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
-
DOI 10.1021/pr049769r
-
Wilson, I.D. et al. High resolution 'ultra performance' liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. J. Proteome Res. 591-598 (2005). (Pubitemid 40548168)
-
(2005)
Journal of Proteome Research
, vol.4
, Issue.2
, pp. 591-598
-
-
Wilson, I.D.1
Nicholson, J.K.2
Castro-Perez, J.3
Granger, J.H.4
Johnson, K.A.5
Smith, B.W.6
Plumb, R.S.7
-
9
-
-
79952712983
-
Gut microbiome-host interactions in health and disease
-
Kinross, J.M., Darzi, A.W. & Nicholson, J.K. Gut microbiome-host interactions in health and disease. Genome Med. 3, 14 (2011).
-
(2011)
Genome Med.
, vol.3
, pp. 14
-
-
Kinross, J.M.1
Darzi, A.W.2
Nicholson, J.K.3
-
10
-
-
80054078496
-
Analytical metabolomics: Nutritional opportunities for personalized health
-
McNiven, E.M., German, J.B. & Slupsky, C.M. Analytical metabolomics: nutritional opportunities for personalized health. J. Nutr. Biochem. 22, 995-1002 (2011).
-
(2011)
J. Nutr. Biochem.
, vol.22
, pp. 995-1002
-
-
McNiven, E.M.1
German, J.B.2
Slupsky, C.M.3
-
11
-
-
80053991414
-
Integration of metabolomics in heart disease and diabetes research: Current achievements and future outlook
-
Dunn, W.B., Goodacre, R., Neyses, L. & Mamas, M. Integration of metabolomics in heart disease and diabetes research: current achievements and future outlook. Bioanalysis 3, 2205-2222 (2011).
-
(2011)
Bioanalysis
, vol.3
, pp. 2205-2222
-
-
Dunn, W.B.1
Goodacre, R.2
Neyses, L.3
Mamas, M.4
-
12
-
-
79952200874
-
NMR and MS methods for metabonomics
-
Dieterle, F. et al. NMR and MS methods for metabonomics. Methods Mol. Biol. 691, 385-415 (2011).
-
(2011)
Methods Mol. Biol.
, vol.691
, pp. 385-415
-
-
Dieterle, F.1
-
13
-
-
80755125363
-
Cross-platform analysis of longitudinal data in metabolomics
-
Nevedomskaya, E., Mayboroda, O.A. & Deelder, A.M. Cross-platform analysis of longitudinal data in metabolomics. Mol. Biosyst. 7, 3214-3222 (2011).
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 3214-3222
-
-
Nevedomskaya, E.1
Mayboroda, O.A.2
Deelder, A.M.3
-
14
-
-
79956224108
-
An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo- p-dioxin
-
Ruiz-Aracama, A. et al. An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. BMC Genomics 12, 251 (2011).
-
(2011)
BMC Genomics
, vol.12
, pp. 251
-
-
Ruiz-Aracama, A.1
-
15
-
-
77956276702
-
Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes
-
Lanza, I.R. et al. Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes. PLoS ONE 5, e10538 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Lanza, I.R.1
-
16
-
-
39149126712
-
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
-
Beckonert, O. et al. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc. 2, 2692-2703 (2007).
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2692-2703
-
-
Beckonert, O.1
-
17
-
-
77956597651
-
High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues
-
Beckonert, O. et al. High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues. Nat. Protoc. 5, 1019-1032 (2010).
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1019-1032
-
-
Beckonert, O.1
-
18
-
-
77952205557
-
Global metabolic profiling procedures for urine using UPLC-MS
-
Want, E.J. et al. Global metabolic profiling procedures for urine using UPLC-MS. Nat. Protoc. 5, 1005-1018 (2010).
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1005-1018
-
-
Want, E.J.1
-
19
-
-
79959913950
-
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
-
Dunn, W.B. et al. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat. Protoc. 6, 1060-1083 (2011).
-
(2011)
Nat. Protoc.
, vol.6
, pp. 1060-1083
-
-
Dunn, W.B.1
-
20
-
-
80053427408
-
Global urinary metabolic profiling procedures using gas chromatography-mass spectrometry
-
Chan, E.C., Pasikanti, K.K. & Nicholson, J.K. Global urinary metabolic profiling procedures using gas chromatography-mass spectrometry. Nat. Protoc. 6, 1483-1499 (2011).
-
(2011)
Nat. Protoc.
, vol.6
, pp. 1483-1499
-
-
Chan, E.C.1
Pasikanti, K.K.2
Nicholson, J.K.3
-
21
-
-
77956586799
-
Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS
-
Masson, P., Alves, A.C., Ebbels, T.M., Nicholson, J.K. & Want, E.J. Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS. Anal. Chem. 82, 7779-7786 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 7779-7786
-
-
Masson, P.1
Alves, A.C.2
Ebbels, T.M.3
Nicholson, J.K.4
Want, E.J.5
-
22
-
-
79952179434
-
Technical and biological variation in UPLC-MS-based untargeted metabolic profiling of liver extracts: Application in an experimental toxicity study on galactosamine
-
Masson, P., Spagou, K., Nicholson, J.K. & Want, E.J. Technical and biological variation in UPLC-MS-based untargeted metabolic profiling of liver extracts: application in an experimental toxicity study on galactosamine. Anal Chem. 83, 1116-1123 (2011).
-
(2011)
Anal Chem.
, vol.83
, pp. 1116-1123
-
-
Masson, P.1
Spagou, K.2
Nicholson, J.K.3
Want, E.J.4
-
23
-
-
79953301627
-
Method for liver tissue metabolic profiling study and its application in type 2 diabetic rats based on ultra performance liquid chromatography-mass spectrometry
-
Huang, Q. et al. Method for liver tissue metabolic profiling study and its application in type 2 diabetic rats based on ultra performance liquid chromatography-mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879, 961-967 (2011).
-
(2011)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.879
, pp. 961-967
-
-
Huang, Q.1
-
24
-
-
79956137695
-
Cross-platform comparison of Caenorhabditis elegans tissue extraction strategies for comprehensive metabolome coverage
-
Geier, F.M., Want, E.J., Leroi, A.M. & Bundy, J.G. Cross-platform comparison of Caenorhabditis elegans tissue extraction strategies for comprehensive metabolome coverage. Anal. Chem. 83, 3730-3736 (2011).
-
(2011)
Anal. Chem.
, vol.83
, pp. 3730-3736
-
-
Geier, F.M.1
Want, E.J.2
Leroi, A.M.3
Bundy, J.G.4
-
25
-
-
80052722283
-
Evaluation of homogenization techniques for the preparation of mouse tissue samples to support drug discovery
-
Liang, X. et al. Evaluation of homogenization techniques for the preparation of mouse tissue samples to support drug discovery. Bioanalysis 3, 1923-1933 (2011).
-
(2011)
Bioanalysis
, vol.3
, pp. 1923-1933
-
-
Liang, X.1
-
26
-
-
36148989929
-
High-throughput tissue extraction protocol for NMR- and MS-based metabolomics
-
DOI 10.1016/j.ab.2007.10.002, PII S0003269707006471
-
Wu, H., Southam, A.D., Hines, A. & Viant, M.R. High-throughput tissue extraction protocol for NMR- and MS-based metabolomics. Anal. Biochem. 372, 204-212 (2008). (Pubitemid 350116777)
-
(2008)
Analytical Biochemistry
, vol.372
, Issue.2
, pp. 204-212
-
-
Wu, H.1
Southam, A.D.2
Hines, A.3
Viant, M.R.4
-
27
-
-
79952749979
-
Systemic gut microbial modulation of bile acid metabolism in host tissue compartments
-
Swann, J.R. et al. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proc. Natl. Acad. Sci. USA 108 (suppl. 1), 4523-4530 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, Issue.SUPPL. 1
, pp. 4523-4530
-
-
Swann, J.R.1
-
28
-
-
50249099816
-
Metabolic phenotyping in health and disease
-
Holmes, E., Wilson, I.D. & Nicholson, J.K. Metabolic phenotyping in health and disease. Cell 134, 714-717 (2008).
-
(2008)
Cell
, vol.134
, pp. 714-717
-
-
Holmes, E.1
Wilson, I.D.2
Nicholson, J.K.3
-
29
-
-
78651243767
-
Imaging mass spectrometry for the assessment of drugs and metabolites in tissue
-
Trim, P.J., Francese, S. & Clench, M.R. Imaging mass spectrometry for the assessment of drugs and metabolites in tissue. Bioanalysis 1, 309-319 (2009).
-
(2009)
Bioanalysis
, vol.1
, pp. 309-319
-
-
Trim, P.J.1
Francese, S.2
Clench, M.R.3
-
30
-
-
68849122017
-
Three-dimensional imaging of metabolites in tissues under ambient conditions by laser ablation electrospray ionization mass spectrometry
-
Nemes, P., Barton, A.A. & Vertes, A. Three-dimensional imaging of metabolites in tissues under ambient conditions by laser ablation electrospray ionization mass spectrometry. Anal. Chem. 81, 6668-6675 (2009).
-
(2009)
Anal. Chem.
, vol.81
, pp. 6668-6675
-
-
Nemes, P.1
Barton, A.A.2
Vertes, A.3
-
31
-
-
13244249953
-
Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS
-
DOI 10.1093/jxb/eri069, Making Sense of the Metabolome
-
Halket, J.M. et al. Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS. J. Exp. Botany 56, 219-243 (2005). (Pubitemid 40181128)
-
(2005)
Journal of Experimental Botany
, vol.56
, Issue.410
, pp. 219-243
-
-
Halket, J.M.1
Waterman, D.2
Przyborowska, A.M.3
Patel, R.K.P.4
Fraser, P.D.5
Bramley, P.M.6
-
32
-
-
0037083636
-
Analysis of highly polar compounds of plant origin: Combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry
-
DOI 10.1006/abio.2001.5513
-
Tolstikov, V.V. & Fiehn, O. Analysis of highly polar compounds of plant origin: combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry. Anal. Biochem. 301, 298-307 (2002). (Pubitemid 34158194)
-
(2002)
Analytical Biochemistry
, vol.301
, Issue.2
, pp. 298-307
-
-
Tolstikov, V.V.1
Fiehn, O.2
-
33
-
-
28444461025
-
Metabolic fingerprinting of rat urine by LC/MS: Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry
-
DOI 10.1016/j.jchromb.2005.07.031, PII S1570023205005192
-
Idborg, H., Zamani, L., Schuppe-Koistinen, I. & Jacobsson, S. Metabolic fingerprinting of rat urine by LC/MS Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry. J. Chromatogr. B. 828, 9-13 (2005). (Pubitemid 41735293)
-
(2005)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.828
, Issue.1-2
, pp. 9-13
-
-
Idborg, H.1
Zamani, L.2
Edlund, P.-O.3
Schuppe-Koistinen, I.4
Jacobsson, S.P.5
-
34
-
-
36849005017
-
Hydrophilic interaction chromatography for mass spectrometric metabonomic studies of urine
-
DOI 10.1021/ac071008v
-
Cubbon, S., Bradbury, T., Wilson, J. & Thomas-Oates, J. Hydrophilic interaction chromatography for mass spectrometric metabonomic studies of urine. Anal. Chem. 79, 8911-8918 (2007). (Pubitemid 350231697)
-
(2007)
Analytical Chemistry
, vol.79
, Issue.23
, pp. 8911-8918
-
-
Cubbon, S.1
Bradbury, T.2
Wilson, J.3
Thomas-Oates, J.4
-
35
-
-
78650769334
-
HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies
-
Spagou, K. et al. HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. Anal. Chem. 83, 382-390 (2011).
-
(2011)
Anal. Chem.
, vol.83
, pp. 382-390
-
-
Spagou, K.1
-
36
-
-
45949087351
-
Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine
-
DOI 10.1002/jssc.200700644, Hydrophilic interaction chromatography
-
Gika, H.G., Theodoridis, G.A. & Wilson, I.D. Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine. J. Sep. Sci. 31, 1598-1608 (2008). (Pubitemid 351890787)
-
(2008)
Journal of Separation Science
, vol.31
, Issue.9
, pp. 1598-1608
-
-
Gika, H.G.1
Theodoridis, G.A.2
Wilson, I.D.3
-
37
-
-
79955371604
-
Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MSn analysis
-
Loftus, N. et al. Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MSn analysis. J. Proteome Res. 10, 705-713 (2011).
-
(2011)
J. Proteome Res.
, vol.10
, pp. 705-713
-
-
Loftus, N.1
-
38
-
-
80053218795
-
LC-MS/MS profiling for detection of endogenous steroids and prostaglandins in tissue samples
-
Surowiec, I., Koc, M., Antti, H., Wikström, P. & Moritz, T. LC-MS/MS profiling for detection of endogenous steroids and prostaglandins in tissue samples. J. Sep. Sci. 34, 2650-2658 (2011).
-
(2011)
J. Sep. Sci.
, vol.34
, pp. 2650-2658
-
-
Surowiec, I.1
Koc, M.2
Antti, H.3
Wikström, P.4
Moritz, T.5
-
39
-
-
77950939754
-
Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry
-
Aaltonen, N., Laitinen, J.T. & Lehtonen, M. Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878, 1145-1152 (2010).
-
(2010)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.878
, pp. 1145-1152
-
-
Aaltonen, N.1
Laitinen, J.T.2
Lehtonen, M.3
-
40
-
-
3042517107
-
1H NMR and HPLC-TOF/MS: Time dependant changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity
-
DOI 10.1039/b400159c
-
Lenz, E.M., Bright, J., Knight, R., Wilson, I.D. & Major, H. A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependant changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. Analyst 129, 535-541 (2004). (Pubitemid 38813520)
-
(2004)
Analyst
, vol.129
, Issue.6
, pp. 535-541
-
-
Lenz, E.M.1
Bright, J.2
Knight, R.3
Wilson, I.D.4
Major, H.5
-
41
-
-
38349103941
-
Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics
-
Nordström, A., Want, E., Northen, T., Lehtiö, J. & Siuzdak, G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics. Anal. Chem. 80, 421-429 (2008).
-
(2008)
Anal. Chem.
, vol.80
, pp. 421-429
-
-
Nordström, A.1
Want, E.2
Northen, T.3
Lehtiö, J.4
Siuzdak, G.5
-
42
-
-
33847238809
-
Ultra-performance liquid chromatography for the determination of pesticide residues in foods by tandem quadrupole mass spectrometry with polarity switching
-
Leandro, C.C., Hancock, P., Fussell, R.J. & Keely, B.J. Ultra-performance liquid chromatography for the determination of pesticide residues in foods by tandem quadrupole mass spectrometry with polarity switching. J. Chromatogr. A 1144, 161-169 (2007).
-
(2007)
J. Chromatogr. A
, vol.1144
, pp. 161-169
-
-
Leandro, C.C.1
Hancock, P.2
Fussell, R.J.3
Keely, B.J.4
-
43
-
-
34548146614
-
Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: Application to human urine
-
DOI 10.1021/pr070183p
-
Gika, H.G., Theodoridis, G.A., Wingate, J.E. & Wilson, I.D. Within day reproducibility of an HPLC-MS-based method for metabonomic analysis: application to human urine. J. Proteome Res. 6, 3291-3303 (2007). (Pubitemid 47310213)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.8
, pp. 3291-3303
-
-
Gika, H.G.1
Theodoridis, G.A.2
Wingate, J.E.3
Wilson, I.D.4
-
44
-
-
48949103703
-
Evaluation of the repeatability of ultra-performance liquid chromatography-TOF-MS for global metabolic profiling of human urine samples
-
Gika, H.G., Macpherson, E., Theodoridis, G. & Wilson, I.D. Evaluation of the repeatability of ultra-performance liquid chromatography-TOF-MS for global metabolic profiling of human urine samples. J. Chromatogr. B 871, 299-305 (2008).
-
(2008)
J. Chromatogr. B
, vol.871
, pp. 299-305
-
-
Gika, H.G.1
MacPherson, E.2
Theodoridis, G.3
Wilson, I.D.4
-
45
-
-
33745077010
-
A metabolomic study of substantial equivalence of field-grown genetically modified wheat
-
DOI 10.1111/j.1467-7652.2006.00197.x
-
Baker, J.M. et al. A metabolomic study of substantial equivalence of field-grown genetically modified wheat. Plant Biotechnol. J. 4, 381-392 (2006). (Pubitemid 43886811)
-
(2006)
Plant Biotechnology Journal
, vol.4
, Issue.4
, pp. 381-392
-
-
Baker, J.M.1
Hawkins, N.D.2
Ward, J.L.3
Lovegrove, A.4
Napier, J.A.5
Shewry, P.R.6
Beale, M.H.7
-
46
-
-
33749074122
-
A pragmatic and readily implemented quality control strategy for HPLC-MS and GC-MS-based metabonomic analysis
-
DOI 10.1039/b604498k
-
Sangster, T., Major, H., Plumb, R., Wilson, A.J. & Wilson, I.D. A pragmatic and readily implemented quality control strategy for HPLC-MS and GC-MS-based metabonomic analysis. Analyst 131, 1075-1078 (2006). (Pubitemid 44465534)
-
(2006)
Analyst
, vol.131
, Issue.10
, pp. 1075-1078
-
-
Sangster, T.1
Major, H.2
Plumb, R.3
Wilson, A.J.4
Wilson, I.D.5
-
47
-
-
0037989030
-
Method development in high-performance liquid chromatography for high-throughput profiling and metabonomic studies of biofluid samples
-
DOI 10.1016/S1570-0232(03)00077-1
-
Pham-Tuan, H., Kaskavelis, L., Daykin, C.A. & Janssen, H.-G. Method development in high-performance liquid chromatography for high-throughput profiling and metabonomic studies of biofluid samples. J. Chromatogr. B 789, 283-301 (2003). (Pubitemid 36549198)
-
(2003)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.789
, Issue.2
, pp. 283-301
-
-
Pham-Tuan, H.1
Kaskavelis, L.2
Daykin, C.A.3
Janssen, H.-G.4
-
48
-
-
32444446805
-
XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
-
DOI 10.1021/ac051437y
-
Smith, C.A., Want, E.J., O'Maille, G., Abagyan, R. & Siuzdak, G. XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal. Chem. 78, 779-787 (2006). (Pubitemid 43228585)
-
(2006)
Analytical Chemistry
, vol.78
, Issue.3
, pp. 779-787
-
-
Smith, C.A.1
Want, E.J.2
O'Maille, G.3
Abagyan, R.4
Siuzdak, G.5
-
49
-
-
33644867564
-
MZmine: Toolbox for processing and visualization of mass spectrometry based molecular profile data
-
DOI 10.1093/bioinformatics/btk039
-
Katajamaa, M., Miettinen, J. & Oresic, M. MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data. Bioinformatics 22, 634-636 (2006). (Pubitemid 43372832)
-
(2006)
Bioinformatics
, vol.22
, Issue.5
, pp. 634-636
-
-
Katajamaa, M.1
Miettinen, J.2
Oresic, M.3
-
50
-
-
0142033903
-
Metabolomics spectral formatting, alignment and conversion tools (MSFACTs)
-
DOI 10.1093/bioinformatics/btg315
-
Duran, A.L., Yang, J., Wang, L.J. & Sumner, L.W. Metabolomics spectral formatting, alignment and conversion tools (MSFACTs). Bioinformatics 19, 2283-2293 (2003). (Pubitemid 37483984)
-
(2003)
Bioinformatics
, vol.19
, Issue.17
, pp. 2283-2293
-
-
Duran, A.L.1
Yang, J.2
Wang, L.3
Sumner, L.W.4
-
51
-
-
33845869336
-
MathDAMP: A package for differential analysis of metabolite profiles
-
Baran, R. et al. MathDAMP: a package for differential analysis of metabolite profiles. BMC Bioinformatics 7, 530-538 (2006).
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 530-538
-
-
Baran, R.1
-
52
-
-
33745728711
-
MET-IDEA: Data extraction tool for mass spectrometry-based metabolomics
-
Broeckling, C.D., Reddy, I.R., Duran, A.L., Zhao, X.C. & Sumner, L.W. MET-IDEA: data extraction tool for mass spectrometry-based metabolomics. Anal. Chem. 78, 4334-4341 (2006).
-
(2006)
Anal. Chem.
, vol.78
, pp. 4334-4341
-
-
Broeckling, C.D.1
Reddy, I.R.2
Duran, A.L.3
Zhao, X.C.4
Sumner, L.W.5
-
53
-
-
34347405493
-
Data processing for mass spectrometry-based metabolomics
-
DOI 10.1016/j.chroma.2007.04.021, PII S0021967307006966, Data Analysis in Chromatography
-
Katajamaa, M. & Oresic, M.J. Data processing for mass spectrometry-based metabolomics. Chromatogr. A 1158, 318-328 (2007). (Pubitemid 47021150)
-
(2007)
Journal of Chromatography A
, vol.1158
, Issue.1-2
, pp. 318-328
-
-
Katajamaa, M.1
Oresic, M.2
-
54
-
-
40549100747
-
Metabolomics data analysis, visualization, and integration
-
Plant Bioinformatics - Methods and Protocols
-
Sumner, L.W., Urbanczyk-Wochniak, E. & Broeckling, C.D. Metabolomics data analysis, visualization, and integration. Methods Mol. Biol. 406, 409-436 (2007). (Pubitemid 351367185)
-
(2007)
Methods in Molecular Biology
, vol.406
, pp. 409-436
-
-
Sumner, L.W.1
Urbanczyk-Wochniak, E.2
Broeckling, C.D.3
-
55
-
-
70149092076
-
Analytical and statistical approaches to metabolomics research
-
Issaq, H.J, Van, Q.N., Waybright, T.J., Muschik, G.M. & Veenstra, T.D. Analytical and statistical approaches to metabolomics research. J. Sep. Sci. 32, 2183-2199 (2009).
-
(2009)
J. Sep. Sci.
, vol.32
, pp. 2183-2199
-
-
Issaq, H.J.1
Van, Q.N.2
Waybright, T.J.3
Muschik, G.M.4
Veenstra, T.D.5
-
56
-
-
79953740072
-
Processing and analysis of GC/LC-MS-based metabolomics data
-
Want, E. & Masson, P. Processing and analysis of GC/LC-MS-based metabolomics data. Methods Mol. Biol. 708, 277-298 (2011).
-
(2011)
Methods Mol. Biol.
, vol.708
, pp. 277-298
-
-
Want, E.1
Masson, P.2
-
57
-
-
74449085466
-
Mass-spectrometry-based metabolomics: Limitations and recommendations for future progress with particular focus on nutrition research
-
Scalbert, A. et al. Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics 5, 435-458 (2009).
-
(2009)
Metabolomics
, vol.5
, pp. 435-458
-
-
Scalbert, A.1
-
58
-
-
84856157713
-
Identification of "known unknowns" utilizing accurate mass data and ChemSpider
-
Little, J.L., Williams, A.J., Pshenichnov, A. & Tkachenko, V. Identification of "known unknowns" utilizing accurate mass data and ChemSpider. J. Am. Soc. Mass Spectrom. 23, 179-185 (2012).
-
(2012)
J. Am. Soc. Mass Spectrom.
, vol.23
, pp. 179-185
-
-
Little, J.L.1
Williams, A.J.2
Pshenichnov, A.3
Tkachenko, V.4
-
59
-
-
33846088138
-
HMDB: The human metabolome database
-
DOI 10.1093/nar/gkl923
-
Wishart, D.S. et al. HMDB: the human metabolome database. Nucleic Acids Res. 35 (Database issue): D521-D526 (2007). (Pubitemid 46056263)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.SUPPL. 1
-
-
Wishart, D.S.1
Tzur, D.2
Knox, C.3
Eisner, R.4
Guo, A.C.5
Young, N.6
Cheng, D.7
Jewell, K.8
Arndt, D.9
Sawhney, S.10
Fung, C.11
Nikolai, L.12
Lewis, M.13
Coutouly, M.-A.14
Forsythe, I.15
Tang, P.16
Shrivastava, S.17
Jeroncic, K.18
Stothard, P.19
Amegbey, G.20
Block, D.21
Hau, D.D.22
Wagner, J.23
Miniaci, J.24
Clements, M.25
Gebremedhin, M.26
Guo, N.27
Zhang, Y.28
Duggan, G.E.29
MacInnis, G.D.30
Weljie, A.M.31
Dowlatabadi, R.32
Bamforth, F.33
Clive, D.34
Greiner, R.35
Li, L.36
Marrie, T.37
Sykes, B.D.38
Vogel, H.J.39
Querengesser, L.40
more..
-
60
-
-
58149202163
-
HMDB: A knowledgebase for the human metabolome
-
Wishart, D.S. et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 37 (Database issue): D603-D610 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.DATABASE ISSUE
-
-
Wishart, D.S.1
-
61
-
-
32444432587
-
METLIN: A metabolite mass spectral database
-
DOI 10.1097/01.ftd.0000179845.53213.39, PII 0000769120051200000016
-
Smith, C.A. et al. METLIN: a metabolite mass spectral database. Ther. Drug Monit. 27, 747-751 (2005). (Pubitemid 44391729)
-
(2005)
Therapeutic Drug Monitoring
, vol.27
, Issue.6
, pp. 747-751
-
-
Smith, C.A.1
O'Maille, G.2
Want, E.J.3
Qin, C.4
Trauger, S.A.5
Brandon, T.R.6
Custodio, D.E.7
Abagyan, R.8
Siuzdak, G.9
-
62
-
-
68949163674
-
Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules'
-
Draper, J. et al. Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules'. BMC Bioinformatics 10, 227 (2009).
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 227
-
-
Draper, J.1
-
63
-
-
66749102638
-
Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile
-
Plumb, R.S. et al. Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile. J. Proteome Res. 8, 2495-2500 (2009).
-
(2009)
J. Proteome Res.
, vol.8
, pp. 2495-2500
-
-
Plumb, R.S.1
-
64
-
-
8544253237
-
Assignment of endogenous substrates to enzymes by global metabolite profiling
-
DOI 10.1021/bi0480335
-
Saghatelian, A. et al. Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry 43, 14332-14339 (2004). (Pubitemid 39491967)
-
(2004)
Biochemistry
, vol.43
, Issue.45
, pp. 14332-14339
-
-
Saghatelian, A.1
Trauger, S.A.2
Want, E.J.3
Hawkins, E.G.4
Siuzdak, G.5
Cravatt, B.F.6
-
65
-
-
39749201504
-
An integrated method for metabolite detection and identification using a linear ion trap/Orbitrap mass spectrometer and multiple data processing techniques: Application to indinavir metabolite detection
-
DOI 10.1002/jms.1311
-
Ruan, Q. et al. An integrated method for metabolite detection and identification using a linear ion trap/Orbitrap mass spectrometer and multiple data processing techniques: application to indinavir metabolite detection. J. Mass Spectrom. 43, 251-261 (2008). (Pubitemid 351303446)
-
(2008)
Journal of Mass Spectrometry
, vol.43
, Issue.2
, pp. 251-261
-
-
Ruan, Q.1
Peterman, S.2
Szewc, M.A.3
Li, M.4
Cui, D.5
Humphreys, W.G.6
Zhu, M.7
-
66
-
-
63449101078
-
Quantitation of small molecules using high-resolution accurate mass spectrometers - A different approach for analysis of biological samples
-
Zhang, N.R. et al. Quantitation of small molecules using high-resolution accurate mass spectrometers - a different approach for analysis of biological samples. Rapid Commun. Mass Spectrom. 23, 1085-1094 (2009).
-
(2009)
Rapid Commun. Mass Spectrom.
, vol.23
, pp. 1085-1094
-
-
Zhang, N.R.1
-
67
-
-
35648961364
-
Metabolic profiling using Fourier-transform ion-cyclotron-resonance mass spectrometry
-
DOI 10.1007/s00216-007-1650-z, Ultrahigh Resolution Mass Spectrometry
-
Ohta, D., Shibata, D. & Kanaya, S. Metabolic profiling using Fourier-transform ion-cyclotron-resonance mass spectrometry. Anal. Bioanal. Chem. 389, 1469-1475 (2007). (Pubitemid 350023671)
-
(2007)
Analytical and Bioanalytical Chemistry
, vol.389
, Issue.5
, pp. 1469-1475
-
-
Ohta, D.1
Shibata, D.2
Kanaya, S.3
-
68
-
-
77956253935
-
Construction of confidence regions for isotopic abundance patterns in LC/MS data sets for rigorous determination of molecular formulas
-
Ipsen, A., Want, E.J. & Ebbels, T.M. Construction of confidence regions for isotopic abundance patterns in LC/MS data sets for rigorous determination of molecular formulas. Anal. Chem. 82, 7319-7328 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 7319-7328
-
-
Ipsen, A.1
Want, E.J.2
Ebbels, T.M.3
-
69
-
-
77749327663
-
A statistically rigorous test for the identification of parent-fragment pairs in LC-MS datasets
-
Ipsen, A., Want, E.J., Lindon, J.C. & Ebbels, T.M. A statistically rigorous test for the identification of parent-fragment pairs in LC-MS datasets. Anal. Chem. 82, 1766-1778 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 1766-1778
-
-
Ipsen, A.1
Want, E.J.2
Lindon, J.C.3
Ebbels, T.M.4
-
70
-
-
34748888866
-
Proposed minimum reporting standards for chemical analysis
-
Sumner, L.W. et al. Proposed minimum reporting standards for chemical analysis. Metabolomics 3, 211-221 (2007).
-
(2007)
Metabolomics
, vol.3
, pp. 211-221
-
-
Sumner, L.W.1
-
71
-
-
41949086183
-
Liquid chromatography and ultra-performance liquid chromatography-mass spectrometry fingerprinting of human urine. Sample stability under different handling and storage conditions for metabonomics studies
-
Gika, H.G., Theodoridis, G. & Wilson, I.D. Liquid chromatography and ultra-performance liquid chromatography-mass spectrometry fingerprinting of human urine. Sample stability under different handling and storage conditions for metabonomics studies. J. Chromatogr. A 1189, 314-322 (2008).
-
(2008)
J. Chromatogr. A
, vol.1189
, pp. 314-322
-
-
Gika, H.G.1
Theodoridis, G.2
Wilson, I.D.3
-
72
-
-
0038296381
-
-
FDA, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM)
-
Food and Drug Administration. FDA Guidance for Industry: Bioanalytical Method Validation. FDA, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM), http://www.fda.gov/downloads/Drugs/.../Guidances/ ucm070107.pdf (2001).
-
(2001)
FDA Guidance for Industry: Bioanalytical Method Validation
-
-
|