High-resolution mass spectrometry for integrated qualitative and quantitative analysis of pharmaceuticals in biological matrices

Analytical and Bioanalytical Chemistry

Volumn 402, Issue 8, 2012, Pages 2587-2596

  Hopfgartner, Gérard ^a   Tonoli, David ^a   Varesio, Emmanuel ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Fast chromatography; High resolution; Mass spectrometry; Metabolism; QUAL QUAN

Indexed keywords

ACQUISITION MODES; BIOLOGICAL FLUIDS; BIOLOGICAL MATRIXES; BOSENTAN; COLLISION CELLS; COLLISION ENERGIES; CONCENTRATION RANGES; FAST CHROMATOGRAPHY; FRAGMENT IONS; HIGH RESOLUTION; HIGH RESOLUTION MASS SPECTROMETRY; HUMAN PLASMAS; INFORMATION-DEPENDENT ACQUISITIONS; MASS SPECTRA; METABOLIC STABILITY; PARACETAMOL; PHARMACEUTICAL COMPOUNDS; PRECURSOR IONS; QUAL/QUAN; QUALITATIVE ANALYSIS; QUALITATIVE AND QUANTITATIVE ANALYSIS; SCAN MODE; SELECTED REACTION MONITORING; THREE ORDERS OF MAGNITUDE; TRIPLE QUADRUPOLE;

BODY FLUIDS; IONS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM;

MERGERS AND ACQUISITIONS;

BOSENTAN; PARACETAMOL; PROPANOLAMINE DERIVATIVE; SULFONAMIDE; TALINOLOL;

ARTICLE; BLOOD; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER MICROSOME; MASS SPECTROMETRY; METABOLISM; URINE;

ACETAMINOPHEN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MASS SPECTROMETRY; MICROSOMES, LIVER; PROPANOLAMINES; SULFONAMIDES;

EID: 84859107186     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5641-8     Document Type: Article

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