High-performance isotope labeling for profiling carboxylic acid-containing metabolites in biofluids by mass spectrometry

Analytical Chemistry

Volumn 82, Issue 21, 2010, Pages 8789-8793

  Guo, Kevin ^a   Li, Liang ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOFLUIDS; CARBOXYLIC ACID GROUPS; CHROMATOGRAPHIC RETENTION; DERIVATIZATIONS; HIGH YIELD; HUMAN URINE; ION PAIRS; ISOTOPE LABELING; LABELING METHODS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; METABOLOME ANALYSIS; ORDERS OF MAGNITUDE; REVERSED PHASE;

BIOMOLECULES; BROMINE COMPOUNDS; CARBOXYLIC ACIDS; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES;

METABOLISM;

BROMIDE; CARBOXYLIC ACID; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS;

ARTICLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; ISOTOPE LABELING; METABOLISM; METABOLOME; METABOLOMICS; METHODOLOGY; REVERSED PHASE LIQUID CHROMATOGRAPHY; URINE;

BROMIDES; CARBOXYLIC ACIDS; CHROMATOGRAPHY, REVERSE-PHASE; HUMANS; INDICATORS AND REAGENTS; ISOTOPE LABELING; METABOLOME; METABOLOMICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 78049517394     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac102146g     Document Type: Article

References (18)

1. Vinayavekhin, N., Homan, E. A., and Saghatelian, A. ACS Chem. Biol. 2010, 5, 91-103
2. Holmes, E., Loo, R. L., Stamler, J., Bictash, M., Yap, I. K. S., Chan, Q., Ebbels, T., De Iorio, M., Brown, I. J., Veselkov, K. A., Daviglus, M. L., Kesteloot, H., Ueshima, H., Zhao, L. C., Nicholson, J. K., and Elliott, P. Nature 2008, 453, 396-U350
3. Scalbert, A., Brennan, L., Fiehn, O., Hankemeier, T., Kristal, B. S., Van Ommen, B., Pujos-Guillot, E., Verheij, E., Wishart, D., and Wopereis, S. Metabolomics 2009, 5, 435-458
4. Ma, S. G., Chowdhury, S. K., and Alton, K. B. Curr. Drug Metab. 2006, 7, 503-523
5. Guo, K. and Li, L. Anal. Chem. 2009, 81, 3919-3932
6. Ji, C. J., Li, W. L., Ren, X. D., El-Kattan, A. F., Kozak, R., Fountain, S., and Lepsy, C. Anal. Chem. 2008, 80, 9195-9203
7. O'Maille, G., Go, E. P., Hoang, L., Want, E. J., Smith, C., O'Maille, P., Nordstrom, A., Morita, H., Qin, C., Uritboonthai, W., Apon, J., Moore, R., Garrett, J., and Siuzdak, G. Spectrosc.: Int. J. 2008, 22, 327-343
8. Shortreed, M. R., Lamos, S. M., Frey, B. L., Phillips, M. F., Patel, M., Belshaw, P. J., and Smith, L. M. Anal. Chem. 2006, 78, 6398-6403
9. Abello, N., Geurink, P. P., Van Der Toorn, M., Van Oosterhout, A. J. M., Lugtenburg, J., Van Der Marel, G. A., Kerstjens, H. A. M., Postma, D. S., Overkleeft, H. S., and Bischoff, R. Anal. Chem. 2008, 80, 9171-9180
10. Eggink, M., Wijtmans, M., Ekkebus, R., Lingeman, H., De Esch, I. J. P., Kool, J., Niessen, W. M. A., and Irth, H. Anal. Chem. 2008, 80, 9042-9051
11. Carlson, E. E. and Cravatt, B. F. J. Am. Chem. Soc. 2007, 129, 15780
12. Johnson, D. W. Clin. Biochem. 2005, 38, 351-361
13. Lamos, S. M., Shortreed, M. R., Frey, B. L., Belshaw, P. J., and Smith, L. M. Anal. Chem. 2007, 79, 5143-5149
14. Wishart, D. S., Knox, C., Guo, A. C., Eisner, R., Young, N., Gautam, B., Hau, D. D., Psychogios, N., Dong, E., Bouatra, S., Mandal, R., Sinelnikov, I., Xia, J. G., Jia, L., Cruz, J. A., Lim, E., Sobsey, C. A., Shrivastava, S., Huang, P., Liu, P., Fang, L., Peng, J., Fradette, R., Cheng, D., Tzur, D., Clements, M., Lewis, A., De Souza, A., Zuniga, A., Dawe, M., Xiong, Y. P., Clive, D., Greiner, R., Nazyrova, A., Shaykhutdinov, R., Li, L., Vogel, H. J., and Forsythe, I. Nucleic Acids Res. 2009, 37, D603-D610
15. Szylhabelgodala, A., Madhavan, S., Rudzinski, J., Oleary, M. H., and Paneth, P. J. Phys. Org. Chem. 1996, 9, 35-40
16. Sekiya, M., Tomie, M., and Leonard, N. J. J. Org. Chem. 1968, 33, 318
17. Diwu, Z. J., Beachdel, C., and Klaubert, D. H. Tetrahedron Lett. 1998, 39, 4987-4990
18. Toyo'oka, T. Anal. Chim. Acta 2002, 465, 111-130