Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

Science

Volumn 336, Issue 6084, 2012, Pages 1040-1044

  Jain, Mohit ^a,b,c,d   Nilsson, Roland ^a,b,c,e   Sharma, Sonia ^f   Madhusudhan, Nikhil ^a,b,c   Kitami, Toshimori ^a,b,c   Souza, Amanda L ^a   Kafri, Ran ^b   Kirschner, Marc W ^b   Clish, Clary B ^a   Mootha, Vamsi K ^a,b,c  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e KAROLINSKA INSTITUTE   (Sweden)

^f LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE;

CANCER; CELL ORGANELLE; CORRELATION; DATA SET; MASS SPECTROMETRY; METABOLITE; MITOCHONDRION; VULNERABILITY;

ARTICLE; BIOSYNTHESIS; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; METABOLITE; MITOCHONDRION; MORTALITY; PRIORITY JOURNAL;

EID: 84861420588     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1218595     Document Type: Article

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