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Volumn 13, Issue 7, 2014, Pages 3420-3431

Metabolomics study of hepatocellular carcinoma: Discovery and validation of serum potential biomarkers by using capillary electrophoresis-mass spectrometry

Author keywords

biomarkers; capillary electrophoresis; HCC; hepatocellular carcinoma; mass spectrometry; metabolomics; serum

Indexed keywords

2 HYDROXYBUTYRIC ACID; ALPHA FETOPROTEIN; ARGININE; GLUTAMINE; HEPATITIS B SURFACE ANTIGEN; HYDROXYBUTYRIC ACID; TRYPTOPHAN; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84903731487     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500390y     Document Type: Article
Times cited : (107)

References (40)
  • 2
    • 79952040779 scopus 로고    scopus 로고
    • Liver Cancer Epidemic in China: Past, Present and Future
    • Chen, J. G.; Zhang, S. W. Liver Cancer Epidemic in China: Past, Present and Future Semin. Cancer Biol. 2011, 21 (1) 59-69
    • (2011) Semin. Cancer Biol. , vol.21 , Issue.1 , pp. 59-69
    • Chen, J.G.1    Zhang, S.W.2
  • 3
    • 58849087179 scopus 로고    scopus 로고
    • Early HCC: Diagnosis and Molecular Markers
    • Sakamoto, M. Early HCC: Diagnosis and Molecular Markers J. Gastroenterol. 2009, 44, 108-111
    • (2009) J. Gastroenterol. , vol.44 , pp. 108-111
    • Sakamoto, M.1
  • 4
    • 0037407560 scopus 로고    scopus 로고
    • Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (HCC) in Adults
    • Ryder, S. D. Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (HCC) in Adults Gut 2003, 52, III1-III8
    • (2003) Gut , vol.52
    • Ryder, S.D.1
  • 5
    • 33847369349 scopus 로고    scopus 로고
    • Hepatocellular Cancer: A Guide for the Internist
    • Parikh, S.; Hyman, D. Hepatocellular Cancer: A Guide for the Internist Am. J. Med. 2007, 120 (3) 194-202
    • (2007) Am. J. Med. , vol.120 , Issue.3 , pp. 194-202
    • Parikh, S.1    Hyman, D.2
  • 6
    • 33644763305 scopus 로고    scopus 로고
    • Accuracy of Ultrasonography, Spiral CT, Magnetic Resonance, and Alpha-Fetoprotein in Diagnosing Hepatocellular Carcinoma: A Systematic Review
    • Colli, A.; Fraquelli, M.; Casazza, G.; Massironi, S.; Colucci, A.; Conte, D.; Duca, P. Accuracy of Ultrasonography, Spiral CT, Magnetic Resonance, and Alpha-Fetoprotein in Diagnosing Hepatocellular Carcinoma: A Systematic Review Am. J. Gastroenterol. 2006, 101 (3) 513-523
    • (2006) Am. J. Gastroenterol. , vol.101 , Issue.3 , pp. 513-523
    • Colli, A.1    Fraquelli, M.2    Casazza, G.3    Massironi, S.4    Colucci, A.5    Conte, D.6    Duca, P.7
  • 13
    • 84863080102 scopus 로고    scopus 로고
    • Metabolomics Study of Stepwise Hepatocarcinogenesis from the Model Rats to Patients: Potential Biomarkers Effective for Small Hepatocellular Carcinoma Diagnosis
    • Tan, Y. X.; Yin, P. Y.; Tang, L.; Xing, W. B.; Huang, Q.; Cao, D.; Zhao, X. J.; Wang, W. Z.; Lu, X.; Xu, Z. L.; Wang, H. Y.; Xu, G. W. Metabolomics Study of Stepwise Hepatocarcinogenesis From the Model Rats to Patients: Potential Biomarkers Effective for Small Hepatocellular Carcinoma Diagnosis Mol. Cell. Proteomics 2012, 11 (2) 12
    • (2012) Mol. Cell. Proteomics , vol.11 , Issue.2 , pp. 12
    • Tan, Y.X.1    Yin, P.Y.2    Tang, L.3    Xing, W.B.4    Huang, Q.5    Cao, D.6    Zhao, X.J.7    Wang, W.Z.8    Lu, X.9    Xu, Z.L.10    Wang, H.Y.11    Xu, G.W.12
  • 14
    • 84863042105 scopus 로고    scopus 로고
    • Metabonomic Profiles Discriminate Hepatocellular Carcinoma from Liver Cirrhosis by Ultraperformance Liquid Chromatography-Mass Spectrometry
    • Wang, B. H.; Chen, D. Y.; Chen, Y.; Hu, Z. H.; Cao, M.; Xie, Q.; Chen, Y. F.; Xu, J. L.; Zheng, S. S.; Li, L. J. Metabonomic Profiles Discriminate Hepatocellular Carcinoma from Liver Cirrhosis by Ultraperformance Liquid Chromatography-Mass Spectrometry J. Proteome Res. 2012, 11 (2) 1217-1227
    • (2012) J. Proteome Res. , vol.11 , Issue.2 , pp. 1217-1227
    • Wang, B.H.1    Chen, D.Y.2    Chen, Y.3    Hu, Z.H.4    Cao, M.5    Xie, Q.6    Chen, Y.F.7    Xu, J.L.8    Zheng, S.S.9    Li, L.J.10
  • 16
    • 78650301750 scopus 로고    scopus 로고
    • CE-MS for Metabolomics: Developments and Applications in the Period 2008-2010
    • Ramautar, R.; Mayboroda, O. A.; Somsen, G. W.; de Jong, G. J. CE-MS for Metabolomics: Developments and Applications in the Period 2008-2010 Electrophoresis 2011, 32 (1) 52-65
    • (2011) Electrophoresis , vol.32 , Issue.1 , pp. 52-65
    • Ramautar, R.1    Mayboroda, O.A.2    Somsen, G.W.3    De Jong, G.J.4
  • 20
    • 33846429217 scopus 로고    scopus 로고
    • Pegylated Recombinant Human Arginase (rhArg-peg(5,000mw)) Inhibits the in Vitro and in Vivo Proliferation of Human Hepatocellular Carcinoma through Arginine Depletion
    • Cheng, P. N. M.; Lam, T. L.; Lam, W. M.; Tsui, S. M.; Cheng, A. W. M.; Lo, W. H.; Leung, Y. C. Pegylated Recombinant Human Arginase (rhArg-peg(5,000mw)) Inhibits the in Vitro and in Vivo Proliferation of Human Hepatocellular Carcinoma through Arginine Depletion Cancer Res. 2007, 67 (1) 309-317
    • (2007) Cancer Res. , vol.67 , Issue.1 , pp. 309-317
    • Cheng, P.N.M.1    Lam, T.L.2    Lam, W.M.3    Tsui, S.M.4    Cheng, A.W.M.5    Lo, W.H.6    Leung, Y.C.7
  • 22
    • 34548146614 scopus 로고    scopus 로고
    • Within-Day Reproducibility of an HPLC-MS-Based Method for Metabonomic Analysis: Application to Human Urine
    • Gika, H. G.; Theodoridis, G. A.; Wingate, J. E.; Wilson, I. D. Within-Day Reproducibility of an HPLC-MS-Based Method for Metabonomic Analysis: Application to Human Urine J. Proteome Res. 2007, 6 (8) 3291-3303
    • (2007) J. Proteome Res. , vol.6 , Issue.8 , pp. 3291-3303
    • Gika, H.G.1    Theodoridis, G.A.2    Wingate, J.E.3    Wilson, I.D.4
  • 24
    • 80054050602 scopus 로고    scopus 로고
    • Bladder Cancer Determination Via Two Urinary Metabolites: A Biomarker Pattern Approach
    • Huang, Z. Z.; Lin, L.; Gao, Y.; Chen, Y. J.; Yan, X. M.; Xing, J. C.; Hang, W. Bladder Cancer Determination Via Two Urinary Metabolites: A Biomarker Pattern Approach Mol. Cell. Proteomics 2011, 10 (10) 10
    • (2011) Mol. Cell. Proteomics , vol.10 , Issue.10 , pp. 10
    • Huang, Z.Z.1    Lin, L.2    Gao, Y.3    Chen, Y.J.4    Yan, X.M.5    Xing, J.C.6    Hang, W.7
  • 25
    • 0030152536 scopus 로고    scopus 로고
    • A SAS Macro for Stepwise Correlated Binary Regression
    • Nuamah, I. F.; Qu, Y.; Amini, S. B. A SAS Macro for Stepwise Correlated Binary Regression Comput. Methods Programs Biomed. 1996, 49 (3) 199-210
    • (1996) Comput. Methods Programs Biomed. , vol.49 , Issue.3 , pp. 199-210
    • Nuamah, I.F.1    Qu, Y.2    Amini, S.B.3
  • 26
    • 84882632229 scopus 로고    scopus 로고
    • Metabolic Characterization of Hepatocellular Carcinoma Using Nontargeted Tissue Metabolomics
    • Huang, Q.; Tan, Y. X.; Yin, P. Y.; Ye, G. Z.; Gao, P.; Lu, X.; Wang, H. Y.; Xu, G. W. Metabolic Characterization of Hepatocellular Carcinoma Using Nontargeted Tissue Metabolomics Cancer Res. 2013, 73 (16) 4992-5002
    • (2013) Cancer Res. , vol.73 , Issue.16 , pp. 4992-5002
    • Huang, Q.1    Tan, Y.X.2    Yin, P.Y.3    Ye, G.Z.4    Gao, P.5    Lu, X.6    Wang, H.Y.7    Xu, G.W.8
  • 27
    • 0002438356 scopus 로고
    • Enquete Permanent dans les Centres Anticancereaux
    • Denoix, P. Enquete Permanent Dans les Centres Anticancereaux Bull. Inst. Natl. Hyg. (Fr.) 1946, 1, 70-75
    • (1946) Bull. Inst. Natl. Hyg. (Fr.) , vol.1 , pp. 70-75
    • Denoix, P.1
  • 28
    • 12444279265 scopus 로고
    • Origin of Cancer Cells
    • Warburg, O. Origin of Cancer Cells Science 1956, 123 (3191) 309-314
    • (1956) Science , vol.123 , Issue.3191 , pp. 309-314
    • Warburg, O.1
  • 30
    • 37449034854 scopus 로고    scopus 로고
    • Beyond Aerobic Glycolysis: Transformed Cells Can Engage in Glutamine Metabolism That Exceeds the Requirement for Protein and Nucleotide Synthesis
    • DeBerardinis, R. J.; Mancuso, A.; Daikhin, E.; Nissim, I.; Yudkoff, M.; Wehrli, S.; Thompson, C. B. Beyond Aerobic Glycolysis: Transformed Cells Can Engage in Glutamine Metabolism That Exceeds the Requirement for Protein and Nucleotide Synthesis Proc. Natl. Acad. Sci. U.S.A. 2007, 104 (49) 19345-19350
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , Issue.49 , pp. 19345-19350
    • Deberardinis, R.J.1    Mancuso, A.2    Daikhin, E.3    Nissim, I.4    Yudkoff, M.5    Wehrli, S.6    Thompson, C.B.7
  • 31
    • 19344365089 scopus 로고    scopus 로고
    • Remission of Hepatocellular Carcinoma with Arginine Depletion Induced by Systemic Release of Endogenous Hepatic Arginase Due to Transhepatic Arterial Embolisation, Augmented by High-Dose Insulin: Arginase As a Potential Drug Candidate for Hepatocellular Carcinoma
    • Cheng, P. N. M.; Leung, Y. C.; Lo, W. H.; Tsui, S. M.; Lam, K. C. Remission of Hepatocellular Carcinoma with Arginine Depletion Induced by Systemic Release of Endogenous Hepatic Arginase Due to Transhepatic Arterial Embolisation, Augmented by High-Dose Insulin: Arginase As a Potential Drug Candidate for Hepatocellular Carcinoma Cancer Lett. 2005, 224 (1) 67-80
    • (2005) Cancer Lett. , vol.224 , Issue.1 , pp. 67-80
    • Cheng, P.N.M.1    Leung, Y.C.2    Lo, W.H.3    Tsui, S.M.4    Lam, K.C.5
  • 32
    • 23044466768 scopus 로고    scopus 로고
    • Arginine Deprivation and Metabolomics: Important Aspects of Intermediary Metabolism in Relation to the Differential Sensitivity of Normal and Tumour Cells
    • Wheatley, D. N. Arginine Deprivation and Metabolomics: Important Aspects of Intermediary Metabolism in Relation to the Differential Sensitivity of Normal and Tumour Cells Semin. Cancer Biol. 2005, 15 (4) 247-253
    • (2005) Semin. Cancer Biol. , vol.15 , Issue.4 , pp. 247-253
    • Wheatley, D.N.1
  • 33
    • 0036093302 scopus 로고    scopus 로고
    • Arginine Catabolism, Liver Extracts and Cancer
    • Wheatley, D. N.; Campbell, E. Arginine Catabolism, Liver Extracts and Cancer Pathol. Oncol. Res. 2002, 8 (1) 18-25
    • (2002) Pathol. Oncol. Res. , vol.8 , Issue.1 , pp. 18-25
    • Wheatley, D.N.1    Campbell, E.2
  • 34
    • 0036402941 scopus 로고    scopus 로고
    • Regulation of Enzymes of the Urea Cycle and Arginine Metabolism
    • Morris, S. M. Regulation of Enzymes of the Urea Cycle and Arginine Metabolism Ann. Rev. Nutr. 2002, 22, 87-105
    • (2002) Ann. Rev. Nutr. , vol.22 , pp. 87-105
    • Morris, S.M.1
  • 35
    • 0041976909 scopus 로고    scopus 로고
    • Arginine Deprivation, Growth Inhibition and Tumour Cell Death: 3. Deficient Utilisation of Citrulline by Malignant Cells
    • Wheatley, D. N.; Campbell, E. Arginine Deprivation, Growth Inhibition and Tumour Cell Death: 3. Deficient Utilisation of Citrulline by Malignant Cells Br. J. Cancer 2003, 89 (3) 573-576
    • (2003) Br. J. Cancer , vol.89 , Issue.3 , pp. 573-576
    • Wheatley, D.N.1    Campbell, E.2
  • 36
    • 84868220730 scopus 로고    scopus 로고
    • Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
    • Platten, M.; Wick, W.; Van den Eynde, B. J. Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion Cancer Res. 2012, 72 (21) 5435-5440
    • (2012) Cancer Res. , vol.72 , Issue.21 , pp. 5435-5440
    • Platten, M.1    Wick, W.2    Van Den Eynde, B.J.3
  • 38
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase
    • Munn, D. H.; Sharma, M. D.; Baban, B.; Harding, H. P.; Zhang, Y. H.; Ron, D.; Mellor, A. L. GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase Immunity 2005, 22 (5) 633-642
    • (2005) Immunity , vol.22 , Issue.5 , pp. 633-642
    • Munn, D.H.1    Sharma, M.D.2    Baban, B.3    Harding, H.P.4    Zhang, Y.H.5    Ron, D.6    Mellor, A.L.7
  • 39
    • 79957963254 scopus 로고    scopus 로고
    • Indoleamine 2,3-Dioxygenase as a Modifier of Pathogenic Inflammation in Cancer and other Inflammation-Associated Diseases
    • Prendergast, G. C.; Chang, M. Y.; Mandik-Nayak, L.; Metz, R.; Muller, A. J. Indoleamine 2,3-Dioxygenase as a Modifier of Pathogenic Inflammation in Cancer and other Inflammation-Associated Diseases Curr. Med. Chem. 2011, 18 (15) 2257-2262
    • (2011) Curr. Med. Chem. , vol.18 , Issue.15 , pp. 2257-2262
    • Prendergast, G.C.1    Chang, M.Y.2    Mandik-Nayak, L.3    Metz, R.4    Muller, A.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.