Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations

Analytica Chimica Acta

Volumn 650, Issue 1, 2009, Pages 3-9

  Chen, Jing ^a   Wang, Wenzhao ^a   Lv, Shen ^b   Yin, Peiyuan ^a   Zhao, Xinjie ^a   Lu, Xin ^a   Zhang, Fengxia ^a   Xu, Guowang ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Biomarker; Hydrophilic interaction chromatography; Liver cancer; Metabolomics; Metabonomics; Ultra performance liquid chromatography mass spectrometry

Indexed keywords

HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIVER CANCER; METABOLOMICS; METABONOMICS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY;

AMIDES; AMINO ACIDS; BIOCHEMISTRY; BIOMARKERS; BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DISCRIMINANT ANALYSIS; DRUG PRODUCTS; FATTY ACIDS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; LIVER; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; METABOLITES; ORGANIC SOLVENTS; SEPARATION;

LIQUIDS;

ACETYLCARNITINE; ACYLCARNITINE; ALANINE; ARGININE; ASPARTIC ACID; CARNITINE; CREATININE; HYPOXANTHINE; LYSINE; NICOTINAMIDE; NICOTINIC ACID; ORGANIC SOLVENT; PROLINE; TRIGONELLINE;

AMINO ACID METABOLISM; ARTICLE; AUTOMATED PATTERN RECOGNITION; BIOINFORMATICS; CHROMATOGRAPHY; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; FATTY ACID OXIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LATENT STRUCTURE ANALYSIS; LIVER CANCER; MASS SPECTROMETRY; METABONOMICS; PARTIAL LEAST SQUARES REGRESSION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; URINALYSIS;

BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISCRIMINANT ANALYSIS; HUMANS; HYDROPHOBICITY; LEAST-SQUARES ANALYSIS; LIVER NEOPLASMS; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; PRINCIPAL COMPONENT ANALYSIS; URINALYSIS;

EID: 69249140995     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2009.03.039     Document Type: Article

References (27)

1. Hollywood K., Brison D.R., and Goodacre R. Proteomics 6 (2006) 4716
2. Nicholson J.K. Mol. Syst. Biol. 2 (2006) article 52
3. Pasikanti K.K., Ho P.C., and Chan E.C.Y. J. Chromatogr. B 871 (2008) 202
4. Benavente F., van der Heijden R., Tjaden U.R., van der Greef J., and Hankemeier T. Electrophoresis 27 (2006) 4570
5. Lu X., Zhao X.J., Bai C.M., Zhao C.X., Lu G., and Xu G.W. J. Chromatogr. B 866 (2008) 64
6. Want E.J., Nordstrom A., Morita H., and Siuzdak G. J. Proteome Res. 6 (2007) 459
7. Gika H.G., Theodoridis G.A., and Wilson I.D. J. Sep. Sci. 31 (2008) 1598
8. Wagner S., Scholz K., Donegan M., Burton L., Wingate J., and Volkel W. Anal. Chem. 78 (2006) 1296
9. Yin P.Y., Zhao X.J., Li Q.R., Wang J.S., Li J.S., and Xu G.W. J. Proteome Res. 5 (2006) 2135
10. Zhao X.J., Wang W.Z., Wang J.S., Yang J., and Xu G.W. J. Sep. Sci. 29 (2006) 2444
11. Hemstrom P., and Irgum K. J. Sep. Sci. 29 (2006) 1784
12. McCalley D.V. J. Chromatogr. A 1171 (2007) 46
13. Diener M., Erler K., Christian B., and Luckas B. J. Sep. Sci. 30 (2007) 1821
14. Idborg H., Zamani L., Edlund P.O., Schuppe-Koistinen I., and Jacobsson S.P. J. Chromatogr. B 828 (2005) 9
15. Cubbon S., Bradbury T., Wilson J., and Thomas-Oates J. Anal. Chem. 79 (2007) 8911
16. Kind T., Tolstikov V., Fiehn O., and Weiss R.H. Anal. Biochem. 363 (2007) 185
17. Kamleh M.A., Hobani Y., Dow J.A.T., and Watson D.G. FEBS Lett. 582 (2008) 2916
18. Wiklund S., Johansson E., Sjöström L., Mellerowicz E.J., Edlund U., Shockcor J.P., Gottfries J., Moritz T., and Trygg J. Anal. Chem. 80 (2008) 115
19. Smith C.A., Want E.J., O'Maille G., Abagyan R., and Siuzdak G. Anal. Chem. 78 (2006) 779
20. Blades A.T., Ikonomou M.G., and Kebarle P. Anal. Chem. 63 (1991) 2109
21. Guidance for Industry Bioanalytical Method Validation, U.S. Department of Health and Human Services, Food and Drug Administration Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM), 2001, p. 8.
22. User's Guide to SIMCA-P, SIMCA-P+ version 11.0; Umetrics AB:Umeå, 2005.
23. Chen J., Zhao X.J., Fritsche J., Yin P.Y., Schmitt-Kopplin P., Wang W.Z., Lu X., Haring H.U., Schleicher E.D., Lehmann R., and Xu G.W. Anal. Chem. 80 (2008) 1280
24. Viglio S., Annovazzi L., Conti B., Genta I., Perugini P., Zanone C., Casado B., Cetta G., and Iadarola P. J. Chromatogr. B 832 (2006) 1
25. Endo F., Hata A., Indo Y., Motohara K., and Matsuda I. J. Inherit. Metab. Dis. 10 (1987) 305
26. Surazynski A., Palka J., and Wolczynski S. Mol. Cell Biochem. 220 (2001) 95
27. Wang Y., Wang J.S., Yao M., Zhao X.J., Fritsche J., Schmitt-Kopplin P., Cai Z.W., Wan D.F., Lu X., Yang S.L., Gu J.R., Haring H.U., Schleicher E.D., Lehmann R., and Xu G.W. Anal. Chem. 80 (2008) 4680