메뉴 건너뛰기




Volumn 13, Issue 2, 2014, Pages 640-649

Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health

Author keywords

bioinformatics; biomarkers; critical illness; hippurate; lactate; lung injury; metabolomics; pharmacotherapy; phospholipids; xanthine oxidase

Indexed keywords

BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; CHROMATOGRAPHY, LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MASS SPECTROMETRY; METABOLOMICS; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 84893854125     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr4007624     Document Type: Article
Times cited : (111)

References (54)
  • 1
    • 0037179653 scopus 로고    scopus 로고
    • Treating sepsis
    • Wenzel, R. P. Treating sepsis N. Engl. J. Med. 2002, 347 (13) 966-7
    • (2002) N. Engl. J. Med. , vol.347 , Issue.13 , pp. 966-967
    • Wenzel, R.P.1
  • 2
    • 78049351610 scopus 로고    scopus 로고
    • The lingering consequences of sepsis: A hidden public health disaster?
    • Angus, D. C. The lingering consequences of sepsis: a hidden public health disaster? JAMA, J. Am. Med. Assoc. 2010, 304 (16) 1833-4
    • (2010) JAMA, J. Am. Med. Assoc. , vol.304 , Issue.16 , pp. 1833-1834
    • Angus, D.C.1
  • 3
    • 84864742993 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • Matthay, M. A.; Ware, L. B.; Zimmerman, G. A. The acute respiratory distress syndrome J. Clin. Invest. 2012, 122 (8) 2731-40
    • (2012) J. Clin. Invest. , vol.122 , Issue.8 , pp. 2731-2740
    • Matthay, M.A.1    Ware, L.B.2    Zimmerman, G.A.3
  • 5
    • 0028888644 scopus 로고
    • Clinical risks for development of the acute respiratory distress syndrome
    • Hudson, L. D.; Milberg, J. A.; Anardi, D.; Maunder, R. J. Clinical risks for development of the acute respiratory distress syndrome Am. J. Respir. Crit. Care Med. 1995, 151 (2 Pt 1) 293-301
    • (1995) Am. J. Respir. Crit. Care Med. , vol.151 , Issue.2 PART 1 , pp. 293-301
    • Hudson, L.D.1    Milberg, J.A.2    Anardi, D.3    Maunder, R.J.4
  • 8
    • 80052922354 scopus 로고    scopus 로고
    • The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses
    • Serkova, N. J.; Standiford, T. J.; Stringer, K. A. The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses Am. J. Respir. Crit. Care Med. 2011, 184 (6) 647-55
    • (2011) Am. J. Respir. Crit. Care Med. , vol.184 , Issue.6 , pp. 647-655
    • Serkova, N.J.1    Standiford, T.J.2    Stringer, K.A.3
  • 9
    • 78650668101 scopus 로고    scopus 로고
    • Metabolic consequences of sepsis-induced acute lung injury revealed by plasma (1)H-nuclear magnetic resonance quantitative metabolomics and computational analysis
    • Stringer, K. A.; Serkova, N. J.; Karnovsky, A.; Guire, K.; Paine, R., 3rd; Standiford, T. J. Metabolic consequences of sepsis-induced acute lung injury revealed by plasma (1)H-nuclear magnetic resonance quantitative metabolomics and computational analysis Am. J. Physiol.: Lung Cell. Mol. Physiol. 2011, 300 (1) L4-L11
    • (2011) Am. J. Physiol.: Lung Cell. Mol. Physiol. , vol.300 , Issue.1
    • Stringer, K.A.1    Serkova, N.J.2    Karnovsky, A.3    Guire, K.4    Paine III, R.5    Standiford, T.J.6
  • 10
    • 38349041898 scopus 로고    scopus 로고
    • Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics
    • Ala-Korpela, M. Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics Clin. Chem. Lab. Med. 2008, 46 (1) 27-42
    • (2008) Clin. Chem. Lab. Med. , vol.46 , Issue.1 , pp. 27-42
    • Ala-Korpela, M.1
  • 12
    • 84859487889 scopus 로고    scopus 로고
    • Measuring metabolomics in acute lung injury: Choosing the correct compartment?
    • Bos, L. D.; Sterk, P. J.; Schultz, M. J. Measuring metabolomics in acute lung injury: choosing the correct compartment? Am. J. Respir. Crit. Care Med. 2012, 185 (7) 789
    • (2012) Am. J. Respir. Crit. Care Med. , vol.185 , Issue.7 , pp. 789
    • Bos, L.D.1    Sterk, P.J.2    Schultz, M.J.3
  • 13
    • 0031834452 scopus 로고    scopus 로고
    • Multiple system organ failure. Is mechanical ventilation a contributing factor?
    • Slutsky, A. S.; Tremblay, L. N. Multiple system organ failure. Is mechanical ventilation a contributing factor? Am. J. Respir. Crit. Care Med. 1998, 157 (6 Pt 1) 1721-5
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , Issue.6 PART 1 , pp. 1721-1725
    • Slutsky, A.S.1    Tremblay, L.N.2
  • 15
    • 66149145894 scopus 로고    scopus 로고
    • Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients
    • Wolak, J. E.; Esther, C. R., Jr.; O'Connell, T. M. Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients Biomarkers 2009, 14 (1) 55-60
    • (2009) Biomarkers , vol.14 , Issue.1 , pp. 55-60
    • Wolak, J.E.1    Esther, Jr.C.R.2    O'Connell, T.M.3
  • 19
    • 77955807773 scopus 로고    scopus 로고
    • Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline
    • Sha, W.; da Costa, K. A.; Fischer, L. M.; Milburn, M. V.; Lawton, K. A.; Berger, A.; Jia, W.; Zeisel, S. H. Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline FASEB J. 2010, 24 (8) 2962-2975
    • (2010) FASEB J. , vol.24 , Issue.8 , pp. 2962-2975
    • Sha, W.1    Da Costa, K.A.2    Fischer, L.M.3    Milburn, M.V.4    Lawton, K.A.5    Berger, A.6    Jia, W.7    Zeisel, S.H.8
  • 20
    • 79955555427 scopus 로고    scopus 로고
    • Reducing Time and Increasing Sensitivity in Sample Preparation for Adherent Mammalian Cell Metabolomics
    • Lorenz, M. A.; Burant, C. F.; Kennedy, R. T. Reducing Time and Increasing Sensitivity in Sample Preparation for Adherent Mammalian Cell Metabolomics Anal. Chem. 2011, 83 (9) 3406-3414
    • (2011) Anal. Chem. , vol.83 , Issue.9 , pp. 3406-3414
    • Lorenz, M.A.1    Burant, C.F.2    Kennedy, R.T.3
  • 21
    • 49549099267 scopus 로고    scopus 로고
    • Analysis of hydrophilic metabolites by high-performance liquid chromatography-mass spectrometry using a silica hydride-based stationary phase
    • Pesek, J. J.; Matyska, M. T.; Fischer, S. M.; Sana, T. R. Analysis of hydrophilic metabolites by high-performance liquid chromatography-mass spectrometry using a silica hydride-based stationary phase J. Chromatogr., A 2008, 1204 (1) 48-55
    • (2008) J. Chromatogr., A , vol.1204 , Issue.1 , pp. 48-55
    • Pesek, J.J.1    Matyska, M.T.2    Fischer, S.M.3    Sana, T.R.4
  • 22
    • 55349093570 scopus 로고    scopus 로고
    • Discriminant Q(2) (DQ(2)) for improved discrimination in PLSDA models
    • Westerhuis, J. A.; van Velzen, E. J. J.; Hoefsloot, H. C. J.; Smilde, A. K. Discriminant Q(2) (DQ(2)) for improved discrimination in PLSDA models Metabolomics 2008, 4 (4) 293-296
    • (2008) Metabolomics , vol.4 , Issue.4 , pp. 293-296
    • Westerhuis, J.A.1    Van Velzen, E.J.J.2    Hoefsloot, H.C.J.3    Smilde, A.K.4
  • 23
    • 0000174867 scopus 로고    scopus 로고
    • Model validation by permutation tests: Applications to variable selection
    • Lindgren, F.; Hansen, B.; Karcher, W.; Sjostrom, M.; Eriksson, L. Model validation by permutation tests: Applications to variable selection J. Chemom. 1996, 10 (5-6) 521-32
    • (1996) J. Chemom. , vol.10 , Issue.56 , pp. 521-532
    • Lindgren, F.1    Hansen, B.2    Karcher, W.3    Sjostrom, M.4    Eriksson, L.5
  • 24
    • 0036020892 scopus 로고    scopus 로고
    • A direct approach to false discovery rates
    • Storey, J. D. A direct approach to false discovery rates J. R. Stat. Soc., Ser. B 2002, 64, 479-498
    • (2002) J. R. Stat. Soc., Ser. B , vol.64 , pp. 479-498
    • Storey, J.D.1
  • 25
    • 1142273091 scopus 로고    scopus 로고
    • Strong control, conservative point estimation, and simultaneous conservative consistency of false discovery rates: A unified approach
    • Storey, J. D.; Taylor, J. E.; Siegmund, D. Strong control, conservative point estimation, and simultaneous conservative consistency of false discovery rates: A unified approach J. R. Stat. Soc., Ser. B 2004, 66, 187-205
    • (2004) J. R. Stat. Soc., Ser. B , vol.66 , pp. 187-205
    • Storey, J.D.1    Taylor, J.E.2    Siegmund, D.3
  • 28
    • 65949124662 scopus 로고    scopus 로고
    • Effects of mainstream cigarette smoke on the global metabolome of human lung epithelial cells
    • Vulimiri, S. V.; Misra, M.; Hamm, J. T.; Mitchell, M.; Berger, A. Effects of mainstream cigarette smoke on the global metabolome of human lung epithelial cells Chem. Res. Toxicol. 2009, 22 (3) 492-503
    • (2009) Chem. Res. Toxicol. , vol.22 , Issue.3 , pp. 492-503
    • Vulimiri, S.V.1    Misra, M.2    Hamm, J.T.3    Mitchell, M.4    Berger, A.5
  • 29
    • 84867753332 scopus 로고    scopus 로고
    • Specific lipid mediator signatures of human phagocytes: Microparticles stimulate macrophage efferocytosis and pro-resolving mediators
    • Dalli, J.; Serhan, C. N. Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators Blood 2012, 120 (15) e60-72
    • (2012) Blood , vol.120 , Issue.15 , pp. 60-72
    • Dalli, J.1    Serhan, C.N.2
  • 33
    • 77249162677 scopus 로고    scopus 로고
    • Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: A randomized clinical trial
    • Jones, A. E.; Shapiro, N. I.; Trzeciak, S.; Arnold, R. C.; Claremont, H. A.; Kline, J. A. Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial JAMA, J. Am. Med. Assoc. 2010, 303 (8) 739-46
    • (2010) JAMA, J. Am. Med. Assoc. , vol.303 , Issue.8 , pp. 739-746
    • Jones, A.E.1    Shapiro, N.I.2    Trzeciak, S.3    Arnold, R.C.4    Claremont, H.A.5    Kline, J.A.6
  • 34
    • 84867135374 scopus 로고    scopus 로고
    • Does lactate measurement performed on admission predict clinical outcome on the intensive care unit? A concise systematic review
    • Borthwick, H. A.; Brunt, L. K.; Mitchem, K. L.; Chaloner, C. Does lactate measurement performed on admission predict clinical outcome on the intensive care unit? A concise systematic review Ann. Clin. Biochem. 2012, 49 (Pt 4) 391-4
    • (2012) Ann. Clin. Biochem. , vol.49 , Issue.PART 4 , pp. 391-394
    • Borthwick, H.A.1    Brunt, L.K.2    Mitchem, K.L.3    Chaloner, C.4
  • 35
    • 0036337801 scopus 로고    scopus 로고
    • Bench-to-bedside review: Lactate and the lung
    • Iscra, F.; Gullo, A.; Biolo, G. Bench-to-bedside review: lactate and the lung Crit. Care 2002, 6 (4) 327-9
    • (2002) Crit. Care , vol.6 , Issue.4 , pp. 327-329
    • Iscra, F.1    Gullo, A.2    Biolo, G.3
  • 36
    • 0032731537 scopus 로고    scopus 로고
    • Pulmonary lactate release in patients with acute lung injury is not attributable to lung tissue hypoxia
    • Routsi, C.; Bardouniotou, H.; Delivoria-Ioannidou, V.; Kazi, D.; Roussos, C.; Zakynthinos, S. Pulmonary lactate release in patients with acute lung injury is not attributable to lung tissue hypoxia Crit. Care Med. 1999, 27 (11) 2469-73
    • (1999) Crit. Care Med. , vol.27 , Issue.11 , pp. 2469-2473
    • Routsi, C.1    Bardouniotou, H.2    Delivoria-Ioannidou, V.3    Kazi, D.4    Roussos, C.5    Zakynthinos, S.6
  • 38
    • 84862772469 scopus 로고    scopus 로고
    • Normal-range blood lactate concentration in septic shock is prognostic and predictive
    • Wacharasint, P.; Nakada, T. A.; Boyd, J. H.; Russell, J. A.; Walley, K. R. Normal-range blood lactate concentration in septic shock is prognostic and predictive Shock 2012, 38 (1) 4-10
    • (2012) Shock , vol.38 , Issue.1 , pp. 4-10
    • Wacharasint, P.1    Nakada, T.A.2    Boyd, J.H.3    Russell, J.A.4    Walley, K.R.5
  • 40
    • 77953187290 scopus 로고    scopus 로고
    • Uric acid promotes an acute inflammatory response to sterile cell death in mice
    • Kono, H.; Chen, C. J.; Ontiveros, F.; Rock, K. L. Uric acid promotes an acute inflammatory response to sterile cell death in mice J. Clin. Invest. 2010, 120 (6) 1939-49
    • (2010) J. Clin. Invest. , vol.120 , Issue.6 , pp. 1939-1949
    • Kono, H.1    Chen, C.J.2    Ontiveros, F.3    Rock, K.L.4
  • 42
    • 0016253144 scopus 로고
    • The reaction of xanthine oxidase with molecular oxygen
    • Olson, J. S.; Ballow, D. P.; Palmer, G.; Massey, V. The reaction of xanthine oxidase with molecular oxygen J. Biol. Chem. 1974, 249 (14) 4350-62
    • (1974) J. Biol. Chem. , vol.249 , Issue.14 , pp. 4350-4362
    • Olson, J.S.1    Ballow, D.P.2    Palmer, G.3    Massey, V.4
  • 43
    • 0029936339 scopus 로고    scopus 로고
    • Xanthine oxidase activity in bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease
    • Pinamonti, S.; Muzzoli, M.; Chicca, M. C.; Papi, A.; Ravenna, F.; Fabbri, L. M.; Ciaccia, A. Xanthine oxidase activity in bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease Free Radical Biol. Med. 1996, 21 (2) 147-55
    • (1996) Free Radical Biol. Med. , vol.21 , Issue.2 , pp. 147-155
    • Pinamonti, S.1    Muzzoli, M.2    Chicca, M.C.3    Papi, A.4    Ravenna, F.5    Fabbri, L.M.6    Ciaccia, A.7
  • 46
    • 77952693346 scopus 로고    scopus 로고
    • Metabolomic analysis of uremic toxins by liquid chromatography/ electrospray ionization-tandem mass spectrometry
    • Kikuchi, K.; Itoh, Y.; Tateoka, R.; Ezawa, A.; Murakami, K.; Niwa, T. Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry J. Chromatogr., B 2010, 878 (20) 1662-1668
    • (2010) J. Chromatogr., B , vol.878 , Issue.20 , pp. 1662-1668
    • Kikuchi, K.1    Itoh, Y.2    Tateoka, R.3    Ezawa, A.4    Murakami, K.5    Niwa, T.6
  • 48
    • 17844404232 scopus 로고    scopus 로고
    • Gut microorganisms, mammalian metabolism and personalized health care
    • Nicholson, J. K.; Holmes, E.; Wilson, I. D. Gut microorganisms, mammalian metabolism and personalized health care Nat. Rev. Microbiol. 2005, 3 (5) 431-8
    • (2005) Nat. Rev. Microbiol. , vol.3 , Issue.5 , pp. 431-438
    • Nicholson, J.K.1    Holmes, E.2    Wilson, I.D.3
  • 50
    • 79960122985 scopus 로고    scopus 로고
    • Update on the pharmacokinetics and redox properties of protein-bound uremic toxins
    • Watanabe, H.; Miyamoto, Y.; Otagiri, M.; Maruyama, T. Update on the pharmacokinetics and redox properties of protein-bound uremic toxins J. Pharm. Sci. 2011, 100 (9) 3682-95
    • (2011) J. Pharm. Sci. , vol.100 , Issue.9 , pp. 3682-3695
    • Watanabe, H.1    Miyamoto, Y.2    Otagiri, M.3    Maruyama, T.4
  • 51
    • 84863775428 scopus 로고    scopus 로고
    • Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production
    • Itoh, Y.; Ezawa, A.; Kikuchi, K.; Tsuruta, Y.; Niwa, T. Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production Anal. Bioanal. Chem. 2012, 403 (7) 1841-50
    • (2012) Anal. Bioanal. Chem. , vol.403 , Issue.7 , pp. 1841-1850
    • Itoh, Y.1    Ezawa, A.2    Kikuchi, K.3    Tsuruta, Y.4    Niwa, T.5
  • 53
    • 0015613437 scopus 로고
    • Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption
    • Cole, M.; Kenig, M. D.; Hewitt, V. A. Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption Antimicrob. Agents Chemother. 1973, 3 (4) 463-8
    • (1973) Antimicrob. Agents Chemother. , vol.3 , Issue.4 , pp. 463-468
    • Cole, M.1    Kenig, M.D.2    Hewitt, V.A.3
  • 54
    • 0036257688 scopus 로고    scopus 로고
    • Propofol metabolites in man following propofol induction and maintenance
    • Favetta, P.; Degoute, C. S.; Perdrix, J. P.; Dufresne, C.; Boulieu, R.; Guitton, J. Propofol metabolites in man following propofol induction and maintenance Br. J. Anaesth. 2002, 88 (5) 653-8 Kidney Diseases Diseases Kidney Diseases
    • (2002) Br. J. Anaesth. , vol.88 , Issue.5 , pp. 653-658
    • Favetta, P.1    Degoute, C.S.2    Perdrix, J.P.3    Dufresne, C.4    Boulieu, R.5    Guitton, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.