Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data

Analytical Chemistry

Volumn 81, Issue 20, 2009, Pages 8538-8544

  Crews, Bridgit ^a   Wikoff, William R ^a   Patti, Gary J ^a   Woo, Hin Koon ^a   Kalisiak, Ewa ^a   Heideker, Johanna ^a   Siuzdak, Gary ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURATE MASS; BIO-MARKER DISCOVERY; BIOFLUIDS; BIOLOGICAL VARIABILITY; BIOLOGICAL VARIATION; CEREBRAL SPINAL FLUIDS; CEREBRO SPINAL FLUIDS; COEFFICIENT OF VARIATION; HEALTHY CONTROLS; HEALTHY HUMANS; HEALTHY INDIVIDUALS; HUMAN PLASMAS; HUMAN SUBJECTS; INHERENT VARIABILITY; INTEGRATED AREAS; INTRA-GROUP; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; MASS SPECTRA; METABOLOMES; METABOLOMICS; METABOLOMICS DATA; REPRODUCIBILITIES; RETENTION TIME; SAMPLE MATRIX; SIMILAR NUMBERS; STATISTICAL SIGNIFICANCE; VARIABILITY ANALYSIS;

BIOMARKERS; FLUORINE CONTAINING POLYMERS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; METABOLITES; PLASMA (HUMAN);

PLASMAS;

BIOLOGICAL MARKER;

ANALYTIC METHOD; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; METABOLOME; METABOLOMICS; PLASMA; REPRODUCIBILITY; STATISTICAL SIGNIFICANCE;

ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BLOOD CHEMICAL ANALYSIS; CEREBROSPINAL FLUID; CHROMATOGRAPHY, LIQUID; DATABASES, FACTUAL; HUMANS; MASS SPECTROMETRY; METABOLOMICS; NONLINEAR DYNAMICS; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS; SOFTWARE;

EID: 70450014840     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9014947     Document Type: Article

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