Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography

Journal of Separation Science

Volumn 33, Issue 21, 2010, Pages 3273-3282

  Hinterwirth, Helmut ^a   Lämmerhofer, Michael ^a   Preinerstorfer, Beatrix ^a   Gargano, Andrea ^a   Reischl, Roland ^a   Bicker, Wolfgang ^a   Trapp, Oliver ^b   Brecker, Lothar ^a   Lindner, Wolfgang ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Charged aerosol detection; Hydrophilic interaction liquid chromatography (HILIC); Mixed mode stationary phase; Reversed phase weak anion exchange material; Sugar phosphate isomers

Indexed keywords

ANION EXCHANGE; CHARGED AEROSOL DETECTION; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; MIXED MODE; SUGAR PHOSPHATE ISOMERS;

ATMOSPHERIC AEROSOLS; CARBOHYDRATES; COALESCENCE; COLUMN CHROMATOGRAPHY; DETECTORS; GLUCOSE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; ION EXCHANGE; ION EXCHANGERS; IONS; ISOMERS; PHOSPHATES; PHOSPHORYLATION; RATE CONSTANTS; REACTION INTERMEDIATES; SUGAR (SUCROSE);

LIQUID SUGAR;

3 PHOSPHOGLYCERIC ACID; 6 PHOSPHATE; CARBOHYDRATE; DIHYDROXYACETONE PHOSPHATE; ENOLASE; GLUCOSAMINE 1; GLYCERALDEHYDE 3 PHOSPHATE; HEXOSE; PENTOSE PHOSPHATE; UNCLASSIFIED DRUG;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CARBOHYDRATE ANALYSIS; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LOW TEMPERATURE; METABOLOMICS; PRIORITY JOURNAL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOMERISM; METABOLOMICS; MOLECULAR STRUCTURE; PHOSPHORYLATION; SUGAR PHOSPHATES;

EID: 78349300605     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201000412     Document Type: Article

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