Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming

DMM Disease Models and Mechanisms

Volumn 7, Issue 9, 2014, Pages 1023-1032

  Zwaans, Bernadette M M ^a   Lombard, David B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

HIF; Metabolic reprogramming; MYC; Sirtuins; Warburg effect

Indexed keywords

GLUCOSE; HYPOXIA INDUCIBLE FACTOR; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 6; SIRTUIN 7; TUMOR SUPPRESSOR PROTEIN; HYPOXIA INDUCIBLE FACTOR 1;

AEROBIC METABOLISM; APOPTOSIS; BIOMASS PRODUCTION; CANCER CELL; CANCER INHIBITION; CARCINOGENESIS; CELL CYCLE REGULATION; CELL METABOLISM; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; DEACETYLATION; ENZYME ACTIVITY; GENE EXPRESSION; GENOMIC INSTABILITY; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; INFLAMMATION; LIPOGENESIS; LONGEVITY; METABOLIC REPROGRAMMING; MITOCHONDRIAL RESPIRATION; OXIDATIVE PHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; TRANSGENICS; WARBURG EFFECT; GENETICS; METABOLISM; NEOPLASM; ONCOGENE MYC; PATHOLOGY; PHYSIOLOGY;

CELL PROLIFERATION; GENES, MYC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-MYC; SIRTUINS;

EID: 84907202296     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.016287     Document Type: Review

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