-
1
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
DOI 10.1016/j.cell.2005.11.044, PII S0092867406000493
-
Mostoslavsky, R. et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124, 315-329, doi:10.1016/j.cell.2005.11. 044 (2006). (Pubitemid 43121980)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.-L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
-
2
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
DOI 10.1038/nature06736, PII NATURE06736
-
Michishita, E. et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452, 492-496, doi:10.1038/nature06736 (2008). (Pubitemid 351450840)
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.A.9
Barrett, J.C.10
Chang, H.Y.11
Bohr, V.A.12
Ried, T.13
Gozani, O.14
Chua, K.F.15
-
3
-
-
58149090925
-
SIRT6 links histoneH3 lysine 9 deacetylation to NF-kappaBdependent gene expression and organismal life span
-
doi:10.1016/j.cell.2008.10.052
-
Kawahara, T. L. et al. SIRT6 links histoneH3 lysine 9 deacetylation to NF-kappaBdependent gene expression and organismal life span. Cell 136, 62-74, doi:10.1016/j.cell.2008.10.052 (2009).
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
-
4
-
-
84870874690
-
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism
-
doi:10.1016/j.cell.2012.10.047
-
Sebastian, C. et al. The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell 151, 1185-1199, doi:10.1016/j.cell.2012. 10.047 (2012).
-
(2012)
Cell
, vol.151
, pp. 1185-1199
-
-
Sebastian, C.1
-
5
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
doi:10.1038/nature10815
-
Kanfi, Y. et al. The sirtuin SIRT6 regulates lifespan in male mice. Nature doi:10.1038/nature10815 (2012).
-
(2012)
Nature
-
-
Kanfi, Y.1
-
6
-
-
66049150672
-
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
-
McCord, R. A. et al. SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging 1, 109-121 (2009).
-
(2009)
Aging
, vol.1
, pp. 109-121
-
-
McCord, R.A.1
-
7
-
-
77956550868
-
Human SIRT6 promotes DNA end resection through CtIP deacetylation
-
doi:10.1126/science.1192049
-
Kaidi, A.,Weinert, B. T., Choudhary, C. & Jackson, S. P. Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science 329, 1348-1353, doi:10.1126/science.1192049 (2010).
-
(2010)
Science
, vol.329
, pp. 1348-1353
-
-
Kaidi, A.1
Weinert, B.T.2
Choudhary, C.3
Jackson, S.P.4
-
8
-
-
84871676013
-
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis
-
doi:10.1016/j.molcel.2012.09.030
-
Dominy Jr, J. E. et al. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Molecular cell 48, 900-913, doi:10.1016/j.molcel.2012.09.030 (2012).
-
(2012)
Molecular Cell
, vol.48
, pp. 900-913
-
-
Dominy Jr., J.E.1
-
9
-
-
79959363092
-
SIRT6 promotes DNA repair under stress by activating PARP1
-
doi:10.1126/science.1202723
-
Mao, Z. et al. SIRT6 promotes DNA repair under stress by activating PARP1. Science 332, 1443-1446, doi:10.1126/science.1202723 (2011).
-
(2011)
Science
, vol.332
, pp. 1443-1446
-
-
Mao, Z.1
-
10
-
-
84875881601
-
SIRT6 regulates TNF-alpha secretion through hydrolysis of longchain fatty acyl lysine
-
doi:10.1038/nature12038
-
Jiang, H. et al. SIRT6 regulates TNF-alpha secretion through hydrolysis of longchain fatty acyl lysine. Nature 496, 110-113, doi:10.1038/nature12038 (2013).
-
(2013)
Nature
, vol.496
, pp. 110-113
-
-
Jiang, H.1
-
11
-
-
39949085583
-
Stress granules: The Tao of RNA triage
-
doi:10.1016/j.tibs.2007.12.003
-
Anderson, P. & Kedersha, N. Stress granules: the Tao of RNA triage. Trends in biochemical sciences 33, 141-150, doi:10.1016/j.tibs.2007.12.003 (2008).
-
(2008)
Trends in Biochemical Sciences
, vol.33
, pp. 141-150
-
-
Anderson, P.1
Kedersha, N.2
-
12
-
-
0037451173
-
The RasGAP-associated endoribonuclease G3BP assembles stress granules
-
DOI 10.1083/jcb.200212128
-
Tourriere, H. et al. The RasGAP-associated endoribonuclease G3BP assembles stress granules. The Journal of cell biology 160, 823-831, doi:10.1083/jcb.200212128 (2003). (Pubitemid 36350838)
-
(2003)
Journal of Cell Biology
, vol.160
, Issue.6
, pp. 823-831
-
-
Tourriere, H.1
Chebli, K.2
Zekri, L.3
Courselaud, B.4
Blanchard, J.M.5
Bertrand, E.6
Tazi, J.7
-
13
-
-
0035963292
-
Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease
-
DOI 10.1038/sj.onc.1204553
-
Soncini, C., Berdo, I. &Draetta, G. Ras-GAP SH3 domain binding protein (G3BP) is amodulator of USP10, a novel human ubiquitin specific protease. Oncogene 20, 3869-3879, doi:10.1038/sj.onc.1204553 (2001). (Pubitemid 32646197)
-
(2001)
Oncogene
, vol.20
, Issue.29
, pp. 3869-3879
-
-
Soncini, C.1
Berdo, I.2
Draetta, G.3
-
14
-
-
33947210861
-
Distinct structural features of Caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2α, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs
-
DOI 10.1128/MCB.02300-06
-
Solomon, S. et al. Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs. Molecular and cellular biology 27, 2324-2342, doi:10.1128/MCB.02300-06 (2007). (Pubitemid 46418485)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.6
, pp. 2324-2342
-
-
Solomon, S.1
Xu, Y.2
Wang, B.3
David, M.D.4
Schubert, P.5
Kennedy, D.6
Schrader, J.W.7
-
15
-
-
84866426158
-
Large G3BP-induced granules trigger eIF2alpha phosphorylation
-
doi:10.1091/mbc.E12-05-0385
-
Reineke, L. C., Dougherty, J. D., Pierre, P. & Lloyd, R. E. Large G3BP-induced granules trigger eIF2alpha phosphorylation. Molecular biology of the cell 23, 3499-3510, doi:10.1091/mbc.E12-05-0385 (2012).
-
(2012)
Molecular Biology of the Cell
, vol.23
, pp. 3499-3510
-
-
Reineke, L.C.1
Dougherty, J.D.2
Pierre, P.3
Lloyd, R.E.4
-
16
-
-
77950035354
-
Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localization
-
doi:10.1016/j.mad.2010.01.006
-
Tennen, R. I., Berber, E. & Chua, K. F. Functional dissection of SIRT6: identification of domains that regulate histone deacetylase activity and chromatin localization. Mech Ageing Dev 131, 185-192, doi:10.1016/j.mad.2010.01. 006 (2010).
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 185-192
-
-
Tennen, R.I.1
Berber, E.2
Chua, K.F.3
-
17
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
doi:10.1126/science.1175371
-
Choudhary, C. et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-840, doi:10.1126/science.1175371 (2009).
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
-
18
-
-
84869192353
-
Regulated protein aggregation: Stress granules and neurodegeneration
-
doi:10.1186/1750-1326-7-56
-
Wolozin, B. Regulated protein aggregation: stress granules and neurodegeneration. Molecular neurodegeneration 7, 56, doi:10.1186/1750-1326-7-56 (2012).
-
(2012)
Molecular Neurodegeneration
, vol.7
, pp. 56
-
-
Wolozin, B.1
-
19
-
-
77956636102
-
Could stress granules be involved in age-related diseases?
-
Gallouzi, I. E. Could stress granules be involved in age-related diseases? Aging 1, 753-757 (2009).
-
(2009)
Aging
, vol.1
, pp. 753-757
-
-
Gallouzi, I.E.1
-
20
-
-
84867686875
-
Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP
-
doi:10.1186/1750-1326-7-54
-
Aulas, A., Stabile, S. & Vande Velde, C. Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP. Molecular neurodegeneration 7, 54, doi:10.1186/1750-1326-7-54 (2012).
-
(2012)
Molecular Neurodegeneration
, vol.7
, pp. 54
-
-
Aulas, A.1
Stabile, S.2
Vande Velde., C.3
-
21
-
-
84866946852
-
C. Elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress
-
doi:10.1371/journal.pgen.1002948
-
Chiang, W. C. et al. C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress. PLoS Genet 8, e1002948, doi:10.1371/journal.pgen.1002948 (2012).
-
(2012)
PLoS Genet
, vol.8
-
-
Chiang, W.C.1
-
22
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
DOI 10.1091/mbc.E05-01-0033
-
Michishita, E., Park, J. Y., Burneskis, J. M., Barrett, J. C. & Horikawa, I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Molecular biology of the cell 16, 4623-4635 (2005). (Pubitemid 41416446)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
23
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam, J.D., Lebovitz, R. M. & Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic acids research 11, 1475-1489 (1983).
-
(1983)
Nucleic Acids Research
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
24
-
-
0033756308
-
Chromatin association of human origin recognition complex, cdc6, and minichromosomemaintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis
-
Mendez, J. & Stillman, B. Chromatin association of human origin recognition complex, cdc6, and minichromosomemaintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Molecular and cellular biology 20, 8602-8612 (2000).
-
(2000)
Molecular and Cellular Biology
, vol.20
, pp. 8602-8612
-
-
Mendez, J.S.1
Stillman, B.2
-
25
-
-
0021355340
-
A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids
-
Wessel, D. & Flugge, U. I. A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. Analytical biochemistry 138, 141-143 (1984). (Pubitemid 14146660)
-
(1984)
Analytical Biochemistry
, vol.138
, Issue.1
, pp. 141-143
-
-
Wessel, D.1
Flugge, U.I.2
-
26
-
-
34548183872
-
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
-
DOI 10.1038/nprot.2007.261, PII NPROT.2007.261
-
Rappsilber, J., Mann, M. & Ishihama, Y. Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips. Nature Protocols 2, 1896-1906 (2007). (Pubitemid 47308128)
-
(2007)
Nature Protocols
, vol.2
, Issue.8
, pp. 1896-1906
-
-
Rappsilber, J.1
Mann, M.2
Ishihama, Y.3
-
27
-
-
78650466243
-
A tissue-specific atlas of mouse protein phosphorylation and expression
-
doi:10.1016/j.cell.2010.12.001
-
Huttlin, E. L. et al. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-1189, doi:10.1016/j.cell.2010.12. 001 (2010).
-
(2010)
Cell
, vol.143
, pp. 1174-1189
-
-
Huttlin, E.L.1
-
28
-
-
33847630405
-
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
-
DOI 10.1038/nmeth1019, PII NMETH1019
-
Elias, J. E. & Gygi, S. P. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nature methods 4, 207-214, doi:10.1038/nmeth1019 (2007). (Pubitemid 46358868)
-
(2007)
Nature Methods
, vol.4
, Issue.3
, pp. 207-214
-
-
Elias, J.E.1
Gygi, S.P.2
-
29
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
doi:10.1038/nprot.2008.211
-
Huang da, W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature protocols 4, 44-57, doi:10.1038/nprot.2008.211 (2009).
-
(2009)
Nature Protocols
, vol.4
, pp. 44-57
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
30
-
-
78651324347
-
The STRING database in 2011: Functional interaction networks of proteins, globally integrated and scored
-
doi:10.1093/nar/gkq973
-
Szklarczyk, D. et al. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic acids research 39, D561-568, doi:10.1093/nar/gkq973 (2011).
-
(2011)
Nucleic Acids Research
, vol.39
-
-
Szklarczyk, D.1
-
31
-
-
57749192735
-
Real-time and quantitative imaging of mammalian stress granules and processing bodies
-
doi:10.1016/S0076-6879(08)02626-8
-
Kedersha, N., Tisdale, S., Hickman, T. & Anderson, P. Real-time and quantitative imaging of mammalian stress granules and processing bodies. Methods in enzymology 448, 521-552, doi:10.1016/S0076-6879(08)02626-8 (2008).
-
(2008)
Methods in Enzymology
, vol.448
, pp. 521-552
-
-
Kedersha, N.1
Tisdale, S.2
Hickman, T.3
Anderson, P.4
-
32
-
-
33845764296
-
A guided tour into subcellular colocalization analysis in light microscopy
-
DOI 10.1111/j.1365-2818.2006.01706.x
-
Bolte, S. & Cordelieres, F. P. A guided tour into subcellular colocalization analysis in light microscopy. Journal of microscopy 224, 213-232, doi:10.1111/j.1365-2818.2006.01706.x (2006). (Pubitemid 46010930)
-
(2006)
Journal of Microscopy
, vol.224
, Issue.3
, pp. 213-232
-
-
Bolte, S.1
Cordelieres, F.P.2
|