-
1
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM and Bos JL. Genetic alterations during colorectal-tumor development. N Engl J Med. 1988; 319(9):525-532.
-
(1988)
N Engl J Med.
, vol.319
, Issue.9
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakamura, Y.7
White, R.8
Smits, A.M.9
Bos, J.L.10
-
2
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B and Kinzler KW. Identification of c-MYC as a target of the APC pathway. Science. 1998; 281(5382):1509-1512.
-
(1998)
Science.
, vol.281
, Issue.5382
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
3
-
-
78649985198
-
Update on the serrated pathway to colorectal carcinoma
-
Snover DC. Update on the serrated pathway to colorectal carcinoma. Hum Pathol. 2011; 42(1):1-10.
-
(2011)
Hum Pathol.
, vol.42
, Issue.1
, pp. 1-10
-
-
Snover, D.C.1
-
4
-
-
66149095468
-
Serrated polyps and colorectal cancer: new pathway to malignancy
-
Noffsinger AE. Serrated polyps and colorectal cancer: new pathway to malignancy. Annu Rev Pathol. 2009; 4:343-364.
-
(2009)
Annu Rev Pathol.
, vol.4
, pp. 343-364
-
-
Noffsinger, A.E.1
-
5
-
-
34248592612
-
Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans
-
Rosenberg DW, Yang S, Pleau DC, Greenspan EJ, Stevens RG, Rajan TV, Heinen CD, Levine J, Zhou Y and O'Brien MJ. Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans. Cancer Res. 2007; 67(8):3551-3554.
-
(2007)
Cancer Res.
, vol.67
, Issue.8
, pp. 3551-3554
-
-
Rosenberg, D.W.1
Yang, S.2
Pleau, D.C.3
Greenspan, E.J.4
Stevens, R.G.5
Rajan, T.V.6
Heinen, C.D.7
Levine, J.8
Zhou, Y.9
O'Brien, M.J.10
-
6
-
-
53149097362
-
BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
-
Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C and Seruca R. BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?. BMC Cancer. 2008; 8:255.
-
(2008)
BMC Cancer.
, vol.8
, pp. 255
-
-
Velho, S.1
Moutinho, C.2
Cirnes, L.3
Albuquerque, C.4
Hamelin, R.5
Schmitt, F.6
Carneiro, F.7
Oliveira, C.8
Seruca, R.9
-
7
-
-
77955525325
-
Ink4a/ Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis
-
Bennecke M, Kriegl L, Bajbouj M, Retzlaff K, Robine S, Jung A, Arkan MC, Kirchner T and Greten FR. Ink4a/ Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis. Cancer Cell. 2010; 18(2):135-146.
-
(2010)
Cancer Cell.
, vol.18
, Issue.2
, pp. 135-146
-
-
Bennecke, M.1
Kriegl, L.2
Bajbouj, M.3
Retzlaff, K.4
Robine, S.5
Jung, A.6
Arkan, M.C.7
Kirchner, T.8
Greten, F.R.9
-
8
-
-
78649307591
-
V600EBRAF induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a
-
Carragher LA, Snell KR, Giblett SM, Aldridge VS, Patel B, Cook SJ, Winton DJ, Marais R and Pritchard CA. V600EBRAF induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a. EMBO Mol Med. 2010; 2(11):458-471.
-
(2010)
EMBO Mol Med.
, vol.2
, Issue.11
, pp. 458-471
-
-
Carragher, L.A.1
Snell, K.R.2
Giblett, S.M.3
Aldridge, V.S.4
Patel, B.5
Cook, S.J.6
Winton, D.J.7
Marais, R.8
Pritchard, C.A.9
-
9
-
-
37549004405
-
Sessile serrated adenoma (SSA) v.s
-
Torlakovic EE, Gomez JD, Driman DK, Parfitt JR, Wang C, Benerjee T and Snover DC. Sessile serrated adenoma (SSA) vs. traditional serrated adenoma (TSA). Am J Surg Pathol. 2008; 32(1):21-29.
-
(2008)
Am J Surg Pathol.
, vol.32
, Issue.1
, pp. 21-29
-
-
Torlakovic, E.E.1
Gomez, J.D.2
Driman, D.K.3
Parfitt, J.R.4
Wang, C.5
Benerjee, T.6
Snover, D.C.7
-
10
-
-
35948935265
-
Hyperplastic and serrated polyps of the colorectum
-
viii
-
O'Brien MJ. Hyperplastic and serrated polyps of the colorectum. Gastroenterol Clin North Am. 2007; 36(4):947-968, viii.
-
(2007)
Gastroenterol Clin North Am.
, vol.36
, Issue.4
, pp. 947-968
-
-
O'brien, M.J.1
-
11
-
-
84856384698
-
The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
-
Menssen A, Hydbring P, Kapelle K, Vervoorts J, Diebold J, Luscher B, Larsson LG and Hermeking H. The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop. Proc Natl Acad Sci U S A. 2012; 109(4):E187-196.
-
(2012)
Proc Natl Acad Sci U S A.
, vol.109
, Issue.4
-
-
Menssen, A.1
Hydbring, P.2
Kapelle, K.3
Vervoorts, J.4
Diebold, J.5
Luscher, B.6
Larsson, L.G.7
Hermeking, H.8
-
12
-
-
84863011183
-
Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib
-
Li L, Wang L, Wang Z, Ho Y, McDonald T, Holyoake TL, Chen W and Bhatia R. Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib. Cancer Cell. 2012; 21(2):266-281.
-
(2012)
Cancer Cell.
, vol.21
, Issue.2
, pp. 266-281
-
-
Li, L.1
Wang, L.2
Wang, Z.3
Ho, Y.4
McDonald, T.5
Holyoake, T.L.6
Chen, W.7
Bhatia, R.8
-
13
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley E, Pearson M, Faretta M, Bauer UM, Frye RA, Minucci S, Pelicci PG and Kouzarides T. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. Embo J. 2002; 21(10):2383-2396.
-
(2002)
Embo J.
, vol.21
, Issue.10
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
14
-
-
0035913903
-
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L and Weinberg RA. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell. 2001; 107(2):149-159.
-
(2001)
Cell.
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
15
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L and Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell. 2001; 107(2):137-148.
-
(2001)
Cell.
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
16
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer?
-
Brooks CL and Gu W. How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer. 2009; 9(2):123-128.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.2
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
-
17
-
-
33646254136
-
Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes
-
Heltweg B, Gatbonton T, Schuler AD, Posakony J, Li H, Goehle S, Kollipara R, Depinho RA, Gu Y, Simon JA and Bedalov A. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 2006; 66(8):4368-4377.
-
(2006)
Cancer Res.
, vol.66
, Issue.8
, pp. 4368-4377
-
-
Heltweg, B.1
Gatbonton, T.2
Schuler, A.D.3
Posakony, J.4
Li, H.5
Goehle, S.6
Kollipara, R.7
Depinho, R.A.8
Gu, Y.9
Simon, J.A.10
Bedalov, A.11
-
18
-
-
62449178216
-
The critical role of the class III histone deacetylase SIRT1 in cancer
-
Liu T, Liu PY and Marshall GM. The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res. 2009; 69(5):1702-1705.
-
(2009)
Cancer Res.
, vol.69
, Issue.5
, pp. 1702-1705
-
-
Liu, T.1
Liu, P.Y.2
Marshall, G.M.3
-
19
-
-
67650691722
-
SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
-
Nosho K, Shima K, Irahara N, Kure S, Firestein R, Baba Y, Toyoda S, Chen L, Hazra A, Giovannucci EL, Fuchs CS and Ogino S. SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Mod Pathol. 2009; 22(7):922-932.
-
(2009)
Mod Pathol.
, vol.22
, Issue.7
, pp. 922-932
-
-
Nosho, K.1
Shima, K.2
Irahara, N.3
Kure, S.4
Firestein, R.5
Baba, Y.6
Toyoda, S.7
Chen, L.8
Hazra, A.9
Giovannucci, E.L.10
Fuchs, C.S.11
Ogino, S.12
-
20
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell. 2006; 127(3):469-480.
-
(2006)
Cell.
, vol.127
, Issue.3
, pp. 469-480
-
-
Clevers, H.1
-
21
-
-
75549090214
-
Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer
-
Neumann J, Zeindl-Eberhart E, Kirchner T and Jung A. Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer. Pathol Res Pract. 2009; 205(12):858-862.
-
(2009)
Pathol Res Pract.
, vol.205
, Issue.12
, pp. 858-862
-
-
Neumann, J.1
Zeindl-Eberhart, E.2
Kirchner, T.3
Jung, A.4
-
22
-
-
23844497341
-
Sensitive sequencing method for KRAS mutation detection by Pyrosequencing
-
Ogino S, Kawasaki T, Brahmandam M, Yan L, Cantor M, Namgyal C, Mino-Kenudson M, Lauwers GY, Loda M and Fuchs CS. Sensitive sequencing method for KRAS mutation detection by Pyrosequencing. J Mol Diagn. 2005; 7(3):413-421.
-
(2005)
J Mol Diagn.
, vol.7
, Issue.3
, pp. 413-421
-
-
Ogino, S.1
Kawasaki, T.2
Brahmandam, M.3
Yan, L.4
Cantor, M.5
Namgyal, C.6
Mino-Kenudson, M.7
Lauwers, G.Y.8
Loda, M.9
Fuchs, C.S.10
-
23
-
-
34447519926
-
K-ras mutation detection in colorectal cancer using the Pyrosequencing technique
-
Poehlmann A, Kuester D, Meyer F, Lippert H, Roessner A and Schneider-Stock R. K-ras mutation detection in colorectal cancer using the Pyrosequencing technique. Pathol Res Pract. 2007; 203(7):489-497.
-
(2007)
Pathol Res Pract.
, vol.203
, Issue.7
, pp. 489-497
-
-
Poehlmann, A.1
Kuester, D.2
Meyer, F.3
Lippert, H.4
Roessner, A.5
Schneider-Stock, R.6
-
24
-
-
0036163763
-
Apoptosis index and apoptosis-related antigen expression in serrated adenoma of the colorectum: the sawtoothed structure may be related to inhibition of apoptosis
-
Tateyama H, Li W, Takahashi E, Miura Y, Sugiura H and Eimoto T. Apoptosis index and apoptosis-related antigen expression in serrated adenoma of the colorectum: the sawtoothed structure may be related to inhibition of apoptosis. Am J Surg Pathol. 2002; 26(2):249-256.
-
(2002)
Am J Surg Pathol.
, vol.26
, Issue.2
, pp. 249-256
-
-
Tateyama, H.1
Li, W.2
Takahashi, E.3
Miura, Y.4
Sugiura, H.5
Eimoto, T.6
-
25
-
-
18144446163
-
Colorectal proliferation and apoptosis in serrated versus conventional adenomacarcinoma pathway: growth, progression and survival
-
Horkko TT and Makinen MJ. Colorectal proliferation and apoptosis in serrated versus conventional adenomacarcinoma pathway: growth, progression and survival. Scand J Gastroenterol. 2003; 38(12):1241-1248.
-
(2003)
Scand J Gastroenterol.
, vol.38
, Issue.12
, pp. 1241-1248
-
-
Horkko, T.T.1
Makinen, M.J.2
-
26
-
-
0038792392
-
Proliferation kinetics and apoptosis of serrated adenoma of the colorectum
-
Komori K, Ajioka Y, Watanabe H, Oda K and Nimura Y. Proliferation kinetics and apoptosis of serrated adenoma of the colorectum. Pathol Int. 2003; 53(5):277-283.
-
(2003)
Pathol Int.
, vol.53
, Issue.5
, pp. 277-283
-
-
Komori, K.1
Ajioka, Y.2
Watanabe, H.3
Oda, K.4
Nimura, Y.5
-
27
-
-
0034548712
-
K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorageindependent growth than codon 13 mutation or protooncogene overexpression
-
Guerrero S, Casanova I, Farre L, Mazo A, Capella G and Mangues R. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorageindependent growth than codon 13 mutation or protooncogene overexpression. Cancer Res. 2000; 60(23):6750-6756.
-
(2000)
Cancer Res.
, vol.60
, Issue.23
, pp. 6750-6756
-
-
Guerrero, S.1
Casanova, I.2
Farre, L.3
Mazo, A.4
Capella, G.5
Mangues, R.6
-
28
-
-
7044253667
-
BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status
-
Yang S, Farraye FA, Mack C, Posnik O and O'Brien MJ. BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004; 28(11):1452-1459.
-
(2004)
Am J Surg Pathol.
, vol.28
, Issue.11
, pp. 1452-1459
-
-
Yang, S.1
Farraye, F.A.2
Mack, C.3
Posnik, O.4
O'brien, M.J.5
-
29
-
-
0042855280
-
Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum
-
Mitomi H, Sada M, Kobayashi K, Igarashi M, Mori A, Kanazawa H, Nishiyama Y, Ihara A and Otani Y. Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum. J Cancer Res Clin Oncol. 2003; 129(8):449-455.
-
(2003)
J Cancer Res Clin Oncol.
, vol.129
, Issue.8
, pp. 449-455
-
-
Mitomi, H.1
Sada, M.2
Kobayashi, K.3
Igarashi, M.4
Mori, A.5
Kanazawa, H.6
Nishiyama, Y.7
Ihara, A.8
Otani, Y.9
-
30
-
-
45849137875
-
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts
-
Huang J, Gan Q, Han L, Li J, Zhang H, Sun Y, Zhang Z and Tong T. SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. PLoS ONE. 2008; 3(3):e1710.
-
(2008)
PLoS ONE.
, vol.3
, Issue.3
-
-
Huang, J.1
Gan, Q.2
Han, L.3
Li, J.4
Zhang, H.5
Sun, Y.6
Zhang, Z.7
Tong, T.8
-
31
-
-
30544445468
-
Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells
-
Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y and Kaneki M. Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells. Oncogene. 2006; 25(2):176-185.
-
(2006)
Oncogene.
, vol.25
, Issue.2
, pp. 176-185
-
-
Ota, H.1
Tokunaga, E.2
Chang, K.3
Hikasa, M.4
Iijima, K.5
Eto, M.6
Kozaki, K.7
Akishita, M.8
Ouchi, Y.9
Kaneki, M.10
-
32
-
-
80053377582
-
Sirt1 deacetylates c-Myc and promotes c-Myc/Max association
-
Mao B, Zhao G, Lv X, Chen HZ, Xue Z, Yang B, Liu DP and Liang CC. Sirt1 deacetylates c-Myc and promotes c-Myc/Max association. Int J Biochem Cell Biol. 2011; 43(11):1573-1581.
-
(2011)
Int J Biochem Cell Biol.
, vol.43
, Issue.11
, pp. 1573-1581
-
-
Mao, B.1
Zhao, G.2
Lv, X.3
Chen, H.Z.4
Xue, Z.5
Yang, B.6
Liu, D.P.7
Liang, C.C.8
-
33
-
-
79959837062
-
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability
-
Marshall GM, Liu PY, Gherardi S, Scarlett CJ, Bedalov A, Xu N, Iraci N, Valli E, Ling D, Thomas W, van Bekkum M, Sekyere E, Jankowski K, Trahair T, Mackenzie KL, Haber M, et al. SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. PLoS Genet. 2011; 7(6):e1002135.
-
(2011)
PLoS Genet.
, vol.7
, Issue.6
-
-
Marshall, G.M.1
Liu, P.Y.2
Gherardi, S.3
Scarlett, C.J.4
Bedalov, A.5
Xu, N.6
Iraci, N.7
Valli, E.8
Ling, D.9
Thomas, W.10
van Bekkum, M.11
Sekyere, E.12
Jankowski, K.13
Trahair, T.14
Mackenzie, K.L.15
Haber, M.16
-
34
-
-
65349096174
-
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation
-
Yuan J, Minter-Dykhouse K and Lou Z. A c-Myc-SIRT1 feedback loop regulates cell growth and transformation. J Cell Biol. 2009; 185(2):203-211.
-
(2009)
J Cell Biol.
, vol.185
, Issue.2
, pp. 203-211
-
-
Yuan, J.1
Minter-Dykhouse, K.2
Lou, Z.3
-
35
-
-
84863792910
-
c-MYC and SIRT1 locked in a vicious cycle
-
Menssen A and Hermeking H. c-MYC and SIRT1 locked in a vicious cycle. Oncotarget. 2012; 3(2):116-117. 36. Sears R, Leone G, DeGregori J and Nevins JR. Ras enhances Myc protein stability. Mol Cell. 1999; 3(2):169-179.
-
(2012)
Oncotarget.
, vol.3
, Issue.2
, pp. 116-117
-
-
Menssen, A.1
Hermeking, H.2
-
37
-
-
0034306997
-
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
-
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K and Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev. 2000; 14(19):2501-2514.
-
(2000)
Genes Dev.
, vol.14
, Issue.19
, pp. 2501-2514
-
-
Sears, R.1
Nuckolls, F.2
Haura, E.3
Taya, Y.4
Tamai, K.5
Nevins, J.R.6
-
38
-
-
32444444938
-
c-Myc phosphorylation is required for cellular response to oxidative stress
-
Benassi B, Fanciulli M, Fiorentino F, Porrello A, Chiorino G, Loda M, Zupi G and Biroccio A. c-Myc phosphorylation is required for cellular response to oxidative stress. Mol Cell. 2006; 21(4):509-519.
-
(2006)
Mol Cell.
, vol.21
, Issue.4
, pp. 509-519
-
-
Benassi, B.1
Fanciulli, M.2
Fiorentino, F.3
Porrello, A.4
Chiorino, G.5
Loda, M.6
Zupi, G.7
Biroccio, A.8
-
39
-
-
0347695988
-
Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization
-
Gregory MA, Qi Y and Hann SR. Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J Biol Chem. 2003; 278(51):51606-51612.
-
(2003)
J Biol Chem.
, vol.278
, Issue.51
, pp. 51606-51612
-
-
Gregory, M.A.1
Qi, Y.2
Hann, S.R.3
-
40
-
-
41649102270
-
Frequent beta-catenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential
-
Wu JM, Montgomery EA and Iacobuzio-Donahue CA. Frequent beta-catenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential. Am J Clin Pathol. 2008; 129(3):416-423.
-
(2008)
Am J Clin Pathol.
, vol.129
, Issue.3
, pp. 416-423
-
-
Wu, J.M.1
Montgomery, E.A.2
Iacobuzio-Donahue, C.A.3
-
41
-
-
73349134675
-
Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation
-
Yachida S, Mudali S, Martin SA, Montgomery EA and Iacobuzio-Donahue CA. Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation. Am J Surg Pathol. 2009; 33(12):1823-1832.
-
(2009)
Am J Surg Pathol.
, vol.33
, Issue.12
, pp. 1823-1832
-
-
Yachida, S.1
Mudali, S.2
Martin, S.A.3
Montgomery, E.A.4
Iacobuzio-Donahue, C.A.5
-
42
-
-
49349087349
-
Serrated adenoma of the colorectum undergoes a proliferation versus differentiation process: new conceptual interpretation of morphogenesis
-
Jiao YF, Nakamura S, Sugai T, Yamada N and Habano W. Serrated adenoma of the colorectum undergoes a proliferation versus differentiation process: new conceptual interpretation of morphogenesis. Oncology. 2008; 74(3-4):127-134.
-
(2008)
Oncology.
, vol.74
, Issue.3-4
, pp. 127-134
-
-
Jiao, Y.F.1
Nakamura, S.2
Sugai, T.3
Yamada, N.4
Habano, W.5
-
43
-
-
71049167623
-
Hypermethylation of APC promoter 1A is associated with moderate activation of Wnt signalling pathway in a subset of colorectal serrated adenomas
-
Fu X, Li J, Li K, Tian X and Zhang Y. Hypermethylation of APC promoter 1A is associated with moderate activation of Wnt signalling pathway in a subset of colorectal serrated adenomas. Histopathology. 2009; 55(5):554-563.
-
(2009)
Histopathology.
, vol.55
, Issue.5
, pp. 554-563
-
-
Fu, X.1
Li, J.2
Li, K.3
Tian, X.4
Zhang, Y.5
-
44
-
-
70349332694
-
Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation
-
Finch AJ, Soucek L, Junttila MR, Swigart LB and Evan GI. Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/ beta-catenin pathway activation. Mol Cell Biol. 2009; 29(19):5306-5315.
-
(2009)
Mol Cell Biol.
, vol.29
, Issue.19
, pp. 5306-5315
-
-
Finch, A.J.1
Soucek, L.2
Junttila, M.R.3
Swigart, L.B.4
Evan, G.I.5
-
45
-
-
0028171968
-
Mediation of c-Myc-induced apoptosis by p53
-
Hermeking H and Eick D. Mediation of c-Myc-induced apoptosis by p53. Science. 1994; 265(5181):2091-2093.
-
(1994)
Science.
, vol.265
, Issue.5181
, pp. 2091-2093
-
-
Hermeking, H.1
Eick, D.2
-
46
-
-
84856319611
-
p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers
-
Bond CE, Umapathy A, Ramsnes I, Greco SA, Zhen Zhao Z, Mallitt KA, Buttenshaw RL, Montgomery GW, Leggett BA and Whitehall VL. p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers. Int J Cancer. 2012; 130(7):1567-1576.
-
(2012)
Int J Cancer.
, vol.130
, Issue.7
, pp. 1567-1576
-
-
Bond, C.E.1
Umapathy, A.2
Ramsnes, I.3
Greco, S.A.4
Zhen Zhao, Z.5
Mallitt, K.A.6
Buttenshaw, R.L.7
Montgomery, G.W.8
Leggett, B.A.9
Whitehall, V.L.10
-
47
-
-
79960009775
-
Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer
-
Kriegl L, Neumann J, Vieth M, Greten FR, Reu S, Jung A and Kirchner T. Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer. Mod Pathol. 2011; 24(7):1015-1022.
-
(2011)
Mod Pathol.
, vol.24
, Issue.7
, pp. 1015-1022
-
-
Kriegl, L.1
Neumann, J.2
Vieth, M.3
Greten, F.R.4
Reu, S.5
Jung, A.6
Kirchner, T.7
-
48
-
-
0037372340
-
Frequent CpG island methylation in serrated adenomas of the colorectum
-
Park SJ, Rashid A, Lee JH, Kim SG, Hamilton SR and Wu TT. Frequent CpG island methylation in serrated adenomas of the colorectum. Am J Pathol. 2003; 162(3):815-822.
-
(2003)
Am J Pathol.
, vol.162
, Issue.3
, pp. 815-822
-
-
Park, S.J.1
Rashid, A.2
Lee, J.H.3
Kim, S.G.4
Hamilton, S.R.5
Wu, T.T.6
-
49
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG and Baylin SB. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2006; 2(3):e40.
-
(2006)
PLoS Genet.
, vol.2
, Issue.3
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
Mcgarvey, K.M.4
Kang, S.H.5
Watkins, D.N.6
Herman, J.G.7
Baylin, S.B.8
-
50
-
-
33748331132
-
Progressive loss of SIRT1 with cell cycle withdrawal
-
Sasaki T, Maier B, Bartke A and Scrable H. Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell. 2006; 5(5):413-422.
-
(2006)
Aging Cell.
, vol.5
, Issue.5
, pp. 413-422
-
-
Sasaki, T.1
Maier, B.2
Bartke, A.3
Scrable, H.4
-
51
-
-
83255186739
-
SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities
-
Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS and Seto E. SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities. Mol Cell Biol. 2011; 31(23):4720-4734.
-
(2011)
Mol Cell Biol.
, vol.31
, Issue.23
, pp. 4720-4734
-
-
Peng, L.1
Yuan, Z.2
Ling, H.3
Fukasawa, K.4
Robertson, K.5
Olashaw, N.6
Koomen, J.7
Chen, J.8
Lane, W.S.9
Seto, E.10
-
52
-
-
84873408603
-
SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells
-
Mar 12(doi:10.1038/onc.2012.83)
-
Wang Z, Yuan H, Roth M, Stark JM, Bhatia R and Chen WY. SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells. Oncogene. 2012; Mar 12(doi:10.1038/onc.2012.83).
-
(2012)
Oncogene.
-
-
Wang, Z.1
Yuan, H.2
Roth, M.3
Stark, J.M.4
Bhatia, R.5
Chen, W.Y.6
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