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Volumn 53, Issue 4, 2014, Pages 534-548

Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex

(28)  Fan, Jun a   Shan, Changliang a   Kang, Hee Bum a   Elf, Shannon a   Xie, Jianxin b   Tucker, Meghan b   Gu, Ting Lei b   Aguiar, Mike b   Lonning, Scott b   Chen, Huaibin c   Mohammadi, Moosa c   Britton, Laura Mae P e   Garcia, Benjamin A e   Alečković, Maša d   Kang, Yibin d   Kaluz, Stefan a   Devi, Narra a   VanMeir, Erwin G a   Hitosugi, Taro a,g   Seo, JaeHo a   more..


Author keywords

[No Author keywords available]

Indexed keywords

ACETYL-COA C-ACETYLTRANSFERASE; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOLYSIS; HUMANS; LYSINE; MALE; MICE; MICE, NUDE; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; NEOPLASMS; PHOSPHORYLATION; PYRUVATE DEHYDROGENASE (LIPOAMIDE); PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE; SIRTUIN 3; TYROSINE;

EID: 84894263431     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2013.12.026     Document Type: Article
Times cited : (244)

References (33)
  • 1
    • 0024549618 scopus 로고
    • Ketone body production and disposal:effects of fasting, diabetes, and exercise
    • Balasse E.O., Féry F. Ketone body production and disposal:effects of fasting, diabetes, and exercise. Diabetes Metab. Rev. 1989, 5:247-270.
    • (1989) Diabetes Metab. Rev. , vol.5 , pp. 247-270
    • Balasse, E.O.1    Féry, F.2
  • 2
    • 79959819034 scopus 로고    scopus 로고
    • SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
    • Bell E.L., Emerling B.M., Ricoult S.J., Guarente L. SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene 2011, 30:2986-2996.
    • (2011) Oncogene , vol.30 , pp. 2986-2996
    • Bell, E.L.1    Emerling, B.M.2    Ricoult, S.J.3    Guarente, L.4
  • 3
    • 3543025709 scopus 로고    scopus 로고
    • Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II
    • Boerner J.L., Demory M.L., Silva C., Parsons S.J. Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II. Mol. Cell. Biol. 2004, 24:7059-7071.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7059-7071
    • Boerner, J.L.1    Demory, M.L.2    Silva, C.3    Parsons, S.J.4
  • 7
    • 0036377351 scopus 로고    scopus 로고
    • Regulation of the activity of the pyruvate dehydrogenase complex
    • Harris R.A., Bowker-Kinley M.M., Huang B., Wu P. Regulation of the activity of the pyruvate dehydrogenase complex. Adv. Enzyme Regul. 2002, 42:249-259.
    • (2002) Adv. Enzyme Regul. , vol.42 , pp. 249-259
    • Harris, R.A.1    Bowker-Kinley, M.M.2    Huang, B.3    Wu, P.4
  • 8
    • 1342325393 scopus 로고    scopus 로고
    • Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components
    • Hiromasa Y., Fujisawa T., Aso Y., Roche T.E. Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components. J.Biol. Chem. 2004, 279:6921-6933.
    • (2004) J.Biol. Chem. , vol.279 , pp. 6921-6933
    • Hiromasa, Y.1    Fujisawa, T.2    Aso, Y.3    Roche, T.E.4
  • 10
    • 0346158376 scopus 로고    scopus 로고
    • Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation
    • Holness M.J., Sugden M.C. Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation. Biochem. Soc. Trans. 2003, 31:1143-1151.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 1143-1151
    • Holness, M.J.1    Sugden, M.C.2
  • 12
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
    • Kim J.W., Tchernyshyov I., Semenza G.L., Dang C.V. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006, 3:177-185.
    • (2006) Cell Metab. , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 13
  • 14
    • 35649014840 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
    • Kim J.W., Gao P., Liu Y.C., Semenza G.L., Dang C.V. Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol. Cell. Biol. 2007, 27:7381-7393.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 7381-7393
    • Kim, J.W.1    Gao, P.2    Liu, Y.C.3    Semenza, G.L.4    Dang, C.V.5
  • 16
    • 22044442973 scopus 로고    scopus 로고
    • Tyrosine kinases as targets for cancer therapy
    • Krause D.S., Van Etten R.A. Tyrosine kinases as targets for cancer therapy. N.Engl. J. Med. 2005, 353:172-187.
    • (2005) N.Engl. J. Med. , vol.353 , pp. 172-187
    • Krause, D.S.1    Van Etten, R.A.2
  • 17
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: cancer's Achilles' heel
    • Kroemer G., Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 2008, 13:472-482.
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 18
    • 84882605310 scopus 로고    scopus 로고
    • Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth
    • Lin R., Tao R., Gao X., Li T., Zhou X., Guan K.L., Xiong Y., Lei Q.Y. Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth. Mol. Cell 2013, 51:506-518.
    • (2013) Mol. Cell , vol.51 , pp. 506-518
    • Lin, R.1    Tao, R.2    Gao, X.3    Li, T.4    Zhou, X.5    Guan, K.L.6    Xiong, Y.7    Lei, Q.Y.8
  • 20
    • 79959371914 scopus 로고    scopus 로고
    • Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth
    • Lv L., Li D., Zhao D., Lin R., Chu Y., Zhang H., Zha Z., Liu Y., Li Z., Xu Y., et al. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Mol. Cell 2011, 42:719-730.
    • (2011) Mol. Cell , vol.42 , pp. 719-730
    • Lv, L.1    Li, D.2    Zhao, D.3    Lin, R.4    Chu, Y.5    Zhang, H.6    Zha, Z.7    Liu, Y.8    Li, Z.9    Xu, Y.10
  • 21
    • 84887206685 scopus 로고    scopus 로고
    • Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization
    • Lv L., Xu Y.P., Zhao D., Li F.L., Wang W., Sasaki N., Jiang Y., Zhou X., Li T.T., Guan K.L., et al. Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization. Mol. Cell 2013, 52:340-352.
    • (2013) Mol. Cell , vol.52 , pp. 340-352
    • Lv, L.1    Xu, Y.P.2    Zhao, D.3    Li, F.L.4    Wang, W.5    Sasaki, N.6    Jiang, Y.7    Zhou, X.8    Li, T.T.9    Guan, K.L.10
  • 23
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I., Cairns R.A., Fontana L., Lim A.L., Denko N.C. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006, 3:187-197.
    • (2006) Cell Metab. , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 25
    • 0035788107 scopus 로고    scopus 로고
    • Pushing the boundaries of molecular replacement with maximum likelihood
    • Read R.J. Pushing the boundaries of molecular replacement with maximum likelihood. Acta Crystallogr. D Biol. Crystallogr. 2001, 57:1373-1382.
    • (2001) Acta Crystallogr. D Biol. Crystallogr. , vol.57 , pp. 1373-1382
    • Read, R.J.1
  • 27
    • 0021268270 scopus 로고
    • Insulin and epidermal growth factor stimulate glycolysis in quiescent 3T3 fibroblasts with no changes in key glycolytic enzyme activities
    • Sumi S., Ichihara K., Kono N., Nonaka K., Tarui S. Insulin and epidermal growth factor stimulate glycolysis in quiescent 3T3 fibroblasts with no changes in key glycolytic enzyme activities. Endocrinol. Jpn. 1984, 31:117-125.
    • (1984) Endocrinol. Jpn. , vol.31 , pp. 117-125
    • Sumi, S.1    Ichihara, K.2    Kono, N.3    Nonaka, K.4    Tarui, S.5
  • 28
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 29
    • 77149120797 scopus 로고    scopus 로고
    • Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux
    • Wang Q., Zhang Y., Yang C., Xiong H., Lin Y., Yao J., Li H., Xie L., Zhao W., Yao Y., et al. Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science 2010, 327:1004-1007.
    • (2010) Science , vol.327 , pp. 1004-1007
    • Wang, Q.1    Zhang, Y.2    Yang, C.3    Xiong, H.4    Lin, Y.5    Yao, J.6    Li, H.7    Xie, L.8    Zhao, W.9    Yao, Y.10
  • 30
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.