메뉴 건너뛰기




Volumn 24, Issue 15, 2014, Pages

Ancient endo-siRNA pathways reveal new tricks

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; MICRORNA; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA;

EID: 84905593866     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2014.06.009     Document Type: Review
Times cited : (61)

References (198)
  • 1
    • 0027751663 scopus 로고
    • The C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • R.C. Lee, R.L. Feinbaum, and V. Ambros The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 1993 843 854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 2
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C elegans
    • B. Wightman, I. Ha, and G. Ruvkun Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans Cell 75 1993 855 862
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 4
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • M. Lagos-Quintana, R. Rauhut, W. Lendeckel, and T. Tuschl Identification of novel genes coding for small expressed RNAs Science 294 2001 853 858
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 5
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • N.C. Lau, L.P. Lim, E.G. Weinstein, and D.P. Bartel An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans Science 294 2001 858 862
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 6
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • R.C. Lee, and V. Ambros An extensive class of small RNAs in Caenorhabditis elegans Science 294 2001 862 864
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 7
    • 0037015239 scopus 로고    scopus 로고
    • CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana
    • W. Park, J. Li, R. Song, J. Messing, and X. Chen CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana Curr. Biol. 12 2002 1484 1495
    • (2002) Curr. Biol. , vol.12 , pp. 1484-1495
    • Park, W.1    Li, J.2    Song, R.3    Messing, J.4    Chen, X.5
  • 8
    • 0035984059 scopus 로고    scopus 로고
    • Endogenous and silencing-associated small RNAs in plants
    • C. Llave, K.D. Kasschau, M.A. Rector, and J.C. Carrington Endogenous and silencing-associated small RNAs in plants Plant Cell 14 2002 1605 1619
    • (2002) Plant Cell , vol.14 , pp. 1605-1619
    • Llave, C.1    Kasschau, K.D.2    Rector, M.A.3    Carrington, J.C.4
  • 9
    • 33845436047 scopus 로고    scopus 로고
    • Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C elegans
    • J.G. Ruby, C. Jan, C. Player, M.J. Axtell, W. Lee, C. Nusbaum, H. Ge, and D.P. Bartel Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans Cell 127 2006 1193 1207
    • (2006) Cell , vol.127 , pp. 1193-1207
    • Ruby, J.G.1    Jan, C.2    Player, C.3    Axtell, M.J.4    Lee, W.5    Nusbaum, C.6    Ge, H.7    Bartel, D.P.8
  • 11
    • 0036738077 scopus 로고    scopus 로고
    • Short RNAs can identify new candidate transposable element families in Arabidopsis
    • M.F. Mette, J. van der Winden, M. Matzke, and A.J. Matzke Short RNAs can identify new candidate transposable element families in Arabidopsis Plant Physiol. 130 2002 6 9
    • (2002) Plant Physiol. , vol.130 , pp. 6-9
    • Mette, M.F.1    Van Der Winden, J.2    Matzke, M.3    Matzke, A.J.4
  • 12
    • 0037072660 scopus 로고    scopus 로고
    • Small RNAs correspond to centromere heterochromatic repeats
    • B.J. Reinhart, and D.P. Bartel Small RNAs correspond to centromere heterochromatic repeats Science 297 2002 1831
    • (2002) Science , vol.297 , pp. 1831
    • Reinhart, B.J.1    Bartel, D.P.2
  • 14
    • 0029024475 scopus 로고
    • Par-1, a gene required for establishing polarity in C elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • S. Guo, and K.J. Kemphues par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed Cell 81 1995 611 620
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 15
    • 0025947975 scopus 로고
    • Production of antisense RNA leads to effective and specific inhibition of gene expression in C elegans muscle
    • A. Fire, D. Albertson, S.W. Harrison, and D.G. Moerman Production of antisense RNA leads to effective and specific inhibition of gene expression in C. elegans muscle Development 113 1991 503 514
    • (1991) Development , vol.113 , pp. 503-514
    • Fire, A.1    Albertson, D.2    Harrison, S.W.3    Moerman, D.G.4
  • 16
    • 0021229867 scopus 로고
    • Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis
    • J.G. Izant, and H. Weintraub Inhibition of thymidine kinase gene expression by anti-sense RNA: a molecular approach to genetic analysis Cell 36 1984 1007 1015
    • (1984) Cell , vol.36 , pp. 1007-1015
    • Izant, J.G.1    Weintraub, H.2
  • 17
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • C. Napoli, C. Lemieux, and R. Jorgensen Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans Plant Cell 2 1990 279 289
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 18
    • 0025405838 scopus 로고
    • Flavonoid genes in petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression
    • A.R. van der Krol, L.A. Mur, M. Beld, J.N. Mol, and A.R. Stuitje Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression Plant Cell 2 1990 291 299
    • (1990) Plant Cell , vol.2 , pp. 291-299
    • Van Der Krol, A.R.1    Mur, L.A.2    Beld, M.3    Mol, J.N.4    Stuitje, A.R.5
  • 19
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • A.J. Hamilton, and D.C. Baulcombe A species of small antisense RNA in posttranscriptional gene silencing in plants Science 286 1999 950 952
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 20
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • S.M. Elbashir, W. Lendeckel, and T. Tuschl RNA interference is mediated by 21- and 22-nucleotide RNAs Genes Dev. 15 2001 188 200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 21
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 22
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • P.D. Zamore, T. Tuschl, P.A. Sharp, and D.P. Bartel RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals Cell 101 2000 25 33
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 23
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 1998 806 811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 24
    • 0032472373 scopus 로고    scopus 로고
    • AGO1 defines a novel locus of Arabidopsis controlling leaf development
    • K. Bohmert, I. Camus, C. Bellini, D. Bouchez, M. Caboche, and C. Benning AGO1 defines a novel locus of Arabidopsis controlling leaf development EMBO J. 17 1998 170 180
    • (1998) EMBO J. , vol.17 , pp. 170-180
    • Bohmert, K.1    Camus, I.2    Bellini, C.3    Bouchez, D.4    Caboche, M.5    Benning, C.6
  • 25
    • 0036009918 scopus 로고    scopus 로고
    • Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance
    • J.B. Morel, C. Godon, P. Mourrain, C. Beclin, S. Boutet, F. Feuerbach, F. Proux, and H. Vaucheret Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance Plant Cell 14 2002 629 639
    • (2002) Plant Cell , vol.14 , pp. 629-639
    • Morel, J.B.1    Godon, C.2    Mourrain, P.3    Beclin, C.4    Boutet, S.5    Feuerbach, F.6    Proux, F.7    Vaucheret, H.8
  • 26
    • 0037076320 scopus 로고    scopus 로고
    • ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos
    • R.W. Williams, and G.M. Rubin ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos Proc. Natl. Acad. Sci. USA 99 2002 6889 6894
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6889-6894
    • Williams, R.W.1    Rubin, G.M.2
  • 27
    • 0036184188 scopus 로고    scopus 로고
    • RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila
    • M. Pal-Bhadra, U. Bhadra, and J.A. Birchler RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila Mol. Cell 9 2002 315 327
    • (2002) Mol. Cell , vol.9 , pp. 315-327
    • Pal-Bhadra, M.1    Bhadra, U.2    Birchler, J.A.3
  • 28
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • T.A. Volpe, C. Kidner, I.M. Hall, G. Teng, S.I. Grewal, and R.A. Martienssen Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi Science 297 2002 1833 1837
    • (2002) Science , vol.297 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.5    Martienssen, R.A.6
  • 30
    • 0034633770 scopus 로고    scopus 로고
    • AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
    • M. Fagard, S. Boutet, J.B. Morel, C. Bellini, and H. Vaucheret AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals Proc. Natl. Acad. Sci. USA 97 2000 11650 11654
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11650-11654
    • Fagard, M.1    Boutet, S.2    Morel, J.B.3    Bellini, C.4    Vaucheret, H.5
  • 31
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C elegans developmental timing
    • A. Grishok, A.E. Pasquinelli, D. Conte, N. Li, S. Parrish, I. Ha, D.L. Baillie, A. Fire, G. Ruvkun, and C.C. Mello Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing Cell 106 2001 23 34
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 32
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • M.A. Carmell, Z. Xuan, M.Q. Zhang, and G.J. Hannon The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis Genes Dev. 16 2002 2733 2742
    • (2002) Genes Dev. , vol.16 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 33
    • 0032443562 scopus 로고    scopus 로고
    • A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal
    • D.N. Cox, A. Chao, J. Baker, L. Chang, D. Qiao, and H. Lin A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal Genes Dev. 12 1998 3715 3727
    • (1998) Genes Dev. , vol.12 , pp. 3715-3727
    • Cox, D.N.1    Chao, A.2    Baker, J.3    Chang, L.4    Qiao, D.5    Lin, H.6
  • 34
    • 0032536782 scopus 로고    scopus 로고
    • Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis
    • B. Moussian, H. Schoof, A. Haecker, G. Jurgens, and T. Laux Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis EMBO J. 17 1998 1799 1809
    • (1998) EMBO J. , vol.17 , pp. 1799-1809
    • Moussian, B.1    Schoof, H.2    Haecker, A.3    Jurgens, G.4    Laux, T.5
  • 35
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C elegans
    • R.F. Ketting, S.E. Fischer, E. Bernstein, T. Sijen, G.J. Hannon, and R.H. Plasterk Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans Genes Dev. 15 2001 2654 2659
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 36
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • S.W. Knight, and B.L. Bass A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans Science 293 2001 2269 2271
    • (2001) Science , vol.293 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 37
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • E. Bernstein, A.A. Caudy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001 363 366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 38
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • G. Hutvagner, J. McLachlan, A.E. Pasquinelli, E. Balint, T. Tuschl, and P.D. Zamore A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA Science 293 2001 834 838
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 39
    • 84877766936 scopus 로고    scopus 로고
    • Molecular mechanisms of RNA interference
    • R.C. Wilson, and J.A. Doudna Molecular mechanisms of RNA interference Annu. Rev. Biophys. 42 2013 217 239
    • (2013) Annu. Rev. Biophys. , vol.42 , pp. 217-239
    • Wilson, R.C.1    Doudna, J.A.2
  • 41
    • 79751485564 scopus 로고    scopus 로고
    • The many faces of RNAi
    • R.F. Ketting The many faces of RNAi Dev. Cell 20 2011 148 161
    • (2011) Dev. Cell , vol.20 , pp. 148-161
    • Ketting, R.F.1
  • 42
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Y.S. Lee, K. Nakahara, J.W. Pham, K. Kim, Z. He, E.J. Sontheimer, and R.W. Carthew Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways Cell 117 2004 69 81
    • (2004) Cell , vol.117 , pp. 69-81
    • Lee, Y.S.1    Nakahara, K.2    Pham, J.W.3    Kim, K.4    He, Z.5    Sontheimer, E.J.6    Carthew, R.W.7
  • 43
    • 0141868916 scopus 로고    scopus 로고
    • R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • Q. Liu, T.A. Rand, S. Kalidas, F. Du, H.E. Kim, D.P. Smith, and X. Wang R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway Science 301 2003 1921 1925
    • (2003) Science , vol.301 , pp. 1921-1925
    • Liu, Q.1    Rand, T.A.2    Kalidas, S.3    Du, F.4    Kim, H.E.5    Smith, D.P.6    Wang, X.7
  • 45
    • 0036752955 scopus 로고    scopus 로고
    • Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
    • D.S. Schwarz, G. Hutvagner, B. Haley, and P.D. Zamore Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways Mol. Cell 10 2002 537 548
    • (2002) Mol. Cell , vol.10 , pp. 537-548
    • Schwarz, D.S.1    Hutvagner, G.2    Haley, B.3    Zamore, P.D.4
  • 47
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • A. Khvorova, A. Reynolds, and S.D. Jayasena Functional siRNAs and miRNAs exhibit strand bias Cell 115 2003 209 216
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 48
    • 75649129754 scopus 로고    scopus 로고
    • Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
    • M. Ghildiyal, J. Xu, H. Seitz, Z. Weng, and P.D. Zamore Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway RNA 16 2010 43 56
    • (2010) RNA , vol.16 , pp. 43-56
    • Ghildiyal, M.1    Xu, J.2    Seitz, H.3    Weng, Z.4    Zamore, P.D.5
  • 50
    • 41349114789 scopus 로고    scopus 로고
    • Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide
    • S. Mi, T. Cai, Y. Hu, Y. Chen, E. Hodges, F. Ni, L. Wu, S. Li, H. Zhou, and C. Long et al. Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide Cell 133 2008 116 127
    • (2008) Cell , vol.133 , pp. 116-127
    • Mi, S.1    Cai, T.2    Hu, Y.3    Chen, Y.4    Hodges, E.5    Ni, F.6    Wu, L.7    Li, S.8    Zhou, H.9    Long, C.10
  • 51
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: An expanding universe
    • M. Ghildiyal, and P.D. Zamore Small silencing RNAs: an expanding universe Nat. Rev. Genet. 10 2009 94 108
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 53
    • 84880770383 scopus 로고    scopus 로고
    • Diversifying microRNA sequence and function
    • S.L. Ameres, and P.D. Zamore Diversifying microRNA sequence and function Nat. Rev. Mol. Cell Biol. 14 2013 475 488
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 475-488
    • Ameres, S.L.1    Zamore, P.D.2
  • 54
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
    • E. Huntzinger, and E. Izaurralde Gene silencing by microRNAs: contributions of translational repression and mRNA decay Nat. Rev. Genet. 12 2011 99 110
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 56
    • 33745336617 scopus 로고    scopus 로고
    • A germline-specific class of small RNAs binds mammalian Piwi proteins
    • A. Girard, R. Sachidanandam, G.J. Hannon, and M.A. Carmell A germline-specific class of small RNAs binds mammalian Piwi proteins Nature 442 2006 199 202
    • (2006) Nature , vol.442 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.J.3    Carmell, M.A.4
  • 57
    • 33745621037 scopus 로고    scopus 로고
    • A novel class of small RNAs in mouse spermatogenic cells
    • S.T. Grivna, E. Beyret, Z. Wang, and H. Lin A novel class of small RNAs in mouse spermatogenic cells Genes Dev. 20 2006 1709 1714
    • (2006) Genes Dev. , vol.20 , pp. 1709-1714
    • Grivna, S.T.1    Beyret, E.2    Wang, Z.3    Lin, H.4
  • 61
    • 84893013259 scopus 로고    scopus 로고
    • To be or not to be a piRNA: Genomic origin and processing of piRNAs
    • A. Le Thomas, K.F. Toth, and A.A. Aravin To be or not to be a piRNA: genomic origin and processing of piRNAs Genome Biol. 15 2014 204
    • (2014) Genome Biol. , vol.15 , pp. 204
    • Le Thomas, A.1    Toth, K.F.2    Aravin, A.A.3
  • 62
    • 84880917068 scopus 로고    scopus 로고
    • PIWI-interacting RNAs: From generation to transgenerational epigenetics
    • M.J. Luteijn, and R.F. Ketting PIWI-interacting RNAs: from generation to transgenerational epigenetics Nat. Rev. Genet. 14 2013 523 534
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 523-534
    • Luteijn, M.J.1    Ketting, R.F.2
  • 64
    • 84880723481 scopus 로고    scopus 로고
    • Biology and mechanisms of short RNAs in Caenorhabditis elegans
    • A. Grishok Biology and mechanisms of short RNAs in Caenorhabditis elegans Adv. Genet. 83 2013 1 69
    • (2013) Adv. Genet. , vol.83 , pp. 1-69
    • Grishok, A.1
  • 65
    • 84896033622 scopus 로고    scopus 로고
    • Seeing the forest for the trees: Annotating small RNA producing genes in plants
    • C. Coruh, S. Shahid, and M.J. Axtell Seeing the forest for the trees: annotating small RNA producing genes in plants Curr. Opin. Plant Biol. 18C 2014 87 95
    • (2014) Curr. Opin. Plant Biol. , vol.18 C , pp. 87-95
    • Coruh, C.1    Shahid, S.2    Axtell, M.J.3
  • 68
    • 44349101881 scopus 로고    scopus 로고
    • Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster
    • K. Okamura, S. Balla, R. Martin, N. Liu, and E.C. Lai Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster Nat. Struct. Mol. Biol. 15 2008 581 590
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 581-590
    • Okamura, K.1    Balla, S.2    Martin, R.3    Liu, N.4    Lai, E.C.5
  • 69
    • 44349084754 scopus 로고    scopus 로고
    • The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
    • K. Okamura, W.J. Chung, J.G. Ruby, H. Guo, D.P. Bartel, and E.C. Lai The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs Nature 453 2008 803 806
    • (2008) Nature , vol.453 , pp. 803-806
    • Okamura, K.1    Chung, W.J.2    Ruby, J.G.3    Guo, H.4    Bartel, D.P.5    Lai, E.C.6
  • 70
    • 44349174824 scopus 로고    scopus 로고
    • Endogenous RNA interference provides a somatic defense against Drosophila transposons
    • W.J. Chung, K. Okamura, R. Martin, and E.C. Lai Endogenous RNA interference provides a somatic defense against Drosophila transposons Curr. Biol. 18 2008 795 802
    • (2008) Curr. Biol. , vol.18 , pp. 795-802
    • Chung, W.J.1    Okamura, K.2    Martin, R.3    Lai, E.C.4
  • 72
    • 70349641600 scopus 로고    scopus 로고
    • Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line
    • N.C. Lau, N. Robine, R. Martin, W.J. Chung, Y. Niki, E. Berezikov, and E.C. Lai Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line Genome Res. 19 2009 1776 1785
    • (2009) Genome Res. , vol.19 , pp. 1776-1785
    • Lau, N.C.1    Robine, N.2    Martin, R.3    Chung, W.J.4    Niki, Y.5    Berezikov, E.6    Lai, E.C.7
  • 74
    • 33745599586 scopus 로고    scopus 로고
    • Identification and characterization of two novel classes of small RNAs in the mouse germline: Retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    • T. Watanabe, A. Takeda, T. Tsukiyama, K. Mise, T. Okuno, H. Sasaki, N. Minami, and H. Imai Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes Genes Dev. 20 2006 1732 1743
    • (2006) Genes Dev. , vol.20 , pp. 1732-1743
    • Watanabe, T.1    Takeda, A.2    Tsukiyama, T.3    Mise, K.4    Okuno, T.5    Sasaki, H.6    Minami, N.7    Imai, H.8
  • 76
    • 84899741616 scopus 로고    scopus 로고
    • The diversity, biogenesis, and activities of endogenous silencing small RNAs in Arabidopsis
    • N.G. Bologna, and O. Voinnet The diversity, biogenesis, and activities of endogenous silencing small RNAs in Arabidopsis Annu. Rev. Plant Biol. 65 2014 473 503
    • (2014) Annu. Rev. Plant Biol. , vol.65 , pp. 473-503
    • Bologna, N.G.1    Voinnet, O.2
  • 77
    • 77649254581 scopus 로고    scopus 로고
    • Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans
    • C.C. Conine, P.J. Batista, W. Gu, J.M. Claycomb, D.A. Chaves, M. Shirayama, and C.C. Mello Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans Proc. Natl. Acad. Sci. USA 107 2010 3588 3593
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 3588-3593
    • Conine, C.C.1    Batista, P.J.2    Gu, W.3    Claycomb, J.M.4    Chaves, D.A.5    Shirayama, M.6    Mello, C.C.7
  • 79
    • 71549147194 scopus 로고    scopus 로고
    • Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans
    • D.M. Pavelec, J. Lachowiec, T.F. Duchaine, H.E. Smith, and S. Kennedy Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans Genetics 183 2009 1283 1295
    • (2009) Genetics , vol.183 , pp. 1283-1295
    • Pavelec, D.M.1    Lachowiec, J.2    Duchaine, T.F.3    Smith, H.E.4    Kennedy, S.5
  • 82
    • 84890860526 scopus 로고    scopus 로고
    • Argonautes promote male fertility and provide a paternal memory of germline gene expression in C elegans
    • C.C. Conine, J.J. Moresco, W. Gu, M. Shirayama, D.J. Conte, J.R.r. Yates, and C.C. Mello Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans Cell 155 2013 1532 1544
    • (2013) Cell , vol.155 , pp. 1532-1544
    • Conine, C.C.1    Moresco, J.J.2    Gu, W.3    Shirayama, M.4    Conte, D.J.5    Mello, C.C.6
  • 85
    • 33846527241 scopus 로고    scopus 로고
    • Distinct populations of primary and secondary effectors during RNAi in C elegans
    • J. Pak, and A. Fire Distinct populations of primary and secondary effectors during RNAi in C. elegans Science 315 2007 241 244
    • (2007) Science , vol.315 , pp. 241-244
    • Pak, J.1    Fire, A.2
  • 87
    • 33846524902 scopus 로고    scopus 로고
    • Secondary siRNAs result from unprimed RNA synthesis and form a distinct class
    • T. Sijen, F.A. Steiner, K.L. Thijssen, and R.H. Plasterk Secondary siRNAs result from unprimed RNA synthesis and form a distinct class Science 315 2007 244 247
    • (2007) Science , vol.315 , pp. 244-247
    • Sijen, T.1    Steiner, F.A.2    Thijssen, K.L.3    Plasterk, R.H.4
  • 88
    • 84869065524 scopus 로고    scopus 로고
    • Protection from feed-forward amplification in an amplified RNAi mechanism
    • J. Pak, J.M. Maniar, C.C. Mello, and A. Fire Protection from feed-forward amplification in an amplified RNAi mechanism Cell 151 2012 885 899
    • (2012) Cell , vol.151 , pp. 885-899
    • Pak, J.1    Maniar, J.M.2    Mello, C.C.3    Fire, A.4
  • 89
    • 84865605458 scopus 로고    scopus 로고
    • Small RNAs in development - Insights from plants
    • X. Chen Small RNAs in development - insights from plants Curr. Opin. Genet. Dev. 22 2012 361 367
    • (2012) Curr. Opin. Genet. Dev. , vol.22 , pp. 361-367
    • Chen, X.1
  • 91
    • 4644286235 scopus 로고    scopus 로고
    • SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis
    • A. Peragine, M. Yoshikawa, G. Wu, H.L. Albrecht, and R.S. Poethig SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis Genes Dev. 18 2004 2368 2379
    • (2004) Genes Dev. , vol.18 , pp. 2368-2379
    • Peragine, A.1    Yoshikawa, M.2    Wu, G.3    Albrecht, H.L.4    Poethig, R.S.5
  • 92
    • 17444430392 scopus 로고    scopus 로고
    • MicroRNA-directed phasing during trans-acting siRNA biogenesis in plants
    • E. Allen, Z. Xie, A.M. Gustafson, and J.C. Carrington microRNA-directed phasing during trans-acting siRNA biogenesis in plants Cell 121 2005 207 221
    • (2005) Cell , vol.121 , pp. 207-221
    • Allen, E.1    Xie, Z.2    Gustafson, A.M.3    Carrington, J.C.4
  • 93
    • 23944483216 scopus 로고    scopus 로고
    • Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs
    • V. Gasciolli, A.C. Mallory, D.P. Bartel, and H. Vaucheret Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs Curr. Biol. 15 2005 1494 1500
    • (2005) Curr. Biol. , vol.15 , pp. 1494-1500
    • Gasciolli, V.1    Mallory, A.C.2    Bartel, D.P.3    Vaucheret, H.4
  • 94
    • 24644481318 scopus 로고    scopus 로고
    • DICER-LIKE 4 functions in trans-acting small interfering RNA biogenesis and vegetative phase change in Arabidopsis thaliana
    • Z. Xie, E. Allen, A. Wilken, and J.C. Carrington DICER-LIKE 4 functions in trans-acting small interfering RNA biogenesis and vegetative phase change in Arabidopsis thaliana Proc. Natl. Acad. Sci. USA 102 2005 12984 12989
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 12984-12989
    • Xie, Z.1    Allen, E.2    Wilken, A.3    Carrington, J.C.4
  • 95
    • 24944491201 scopus 로고    scopus 로고
    • A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis
    • M. Yoshikawa, A. Peragine, M.Y. Park, and R.S. Poethig A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis Genes Dev. 19 2005 2164 2175
    • (2005) Genes Dev. , vol.19 , pp. 2164-2175
    • Yoshikawa, M.1    Peragine, A.2    Park, M.Y.3    Poethig, R.S.4
  • 96
    • 28444464041 scopus 로고    scopus 로고
    • DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal
    • P. Dunoyer, C. Himber, and O. Voinnet DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal Nat. Genet. 37 2005 1356 1360
    • (2005) Nat. Genet. , vol.37 , pp. 1356-1360
    • Dunoyer, P.1    Himber, C.2    Voinnet, O.3
  • 97
    • 77956975564 scopus 로고    scopus 로고
    • RNA-directed DNA methylation: Mechanisms and functions
    • M.M. Mahfouz RNA-directed DNA methylation: mechanisms and functions Plant Signal. Behav. 5 2010 806 816
    • (2010) Plant Signal. Behav. , vol.5 , pp. 806-816
    • Mahfouz, M.M.1
  • 99
    • 78650306521 scopus 로고    scopus 로고
    • Small RNA sorting: Matchmaking for Argonautes
    • B. Czech, and G.J. Hannon Small RNA sorting: matchmaking for Argonautes Nat. Rev. Genet. 12 2011 19 31
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 19-31
    • Czech, B.1    Hannon, G.J.2
  • 100
    • 37549014207 scopus 로고    scopus 로고
    • Argonaute proteins: Key players in RNA silencing
    • G. Hutvagner, and M.J. Simard Argonaute proteins: key players in RNA silencing Nat. Rev. Mol. Cell Biol. 9 2008 22 32
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 22-32
    • Hutvagner, G.1    Simard, M.J.2
  • 102
    • 80052956817 scopus 로고    scopus 로고
    • Compatibility with killer explains the rise of RNAi-deficient fungi
    • I.A. Drinnenberg, G.R. Fink, and D.P. Bartel Compatibility with killer explains the rise of RNAi-deficient fungi Science 333 2011 1592
    • (2011) Science , vol.333 , pp. 1592
    • Drinnenberg, I.A.1    Fink, G.R.2    Bartel, D.P.3
  • 103
    • 33645997706 scopus 로고    scopus 로고
    • Yeast viral killer toxins: Lethality and self-protection
    • M.J. Schmitt, and F. Breinig Yeast viral killer toxins: lethality and self-protection Nat. Rev. Microbiol. 4 2006 212 221
    • (2006) Nat. Rev. Microbiol. , vol.4 , pp. 212-221
    • Schmitt, M.J.1    Breinig, F.2
  • 104
    • 84880531520 scopus 로고    scopus 로고
    • Functional diversification of Argonautes in nematodes: An expanding universe
    • A.H. Buck, and M. Blaxter Functional diversification of Argonautes in nematodes: an expanding universe Biochem. Soc. Trans. 41 2013 881 886
    • (2013) Biochem. Soc. Trans. , vol.41 , pp. 881-886
    • Buck, A.H.1    Blaxter, M.2
  • 105
    • 84876739532 scopus 로고    scopus 로고
    • Eukaryotic Argonautes come into focus
    • C.D. Kuhn, and L. Joshua-Tor Eukaryotic Argonautes come into focus Trends Biochem. Sci. 38 2013 263 271
    • (2013) Trends Biochem. Sci. , vol.38 , pp. 263-271
    • Kuhn, C.D.1    Joshua-Tor, L.2
  • 106
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • S.M. Hammond, E. Bernstein, D. Beach, and G.J. Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature 404 2000 293 296
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 107
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • S.M. Hammond, S. Boettcher, A.A. Caudy, R. Kobayashi, and G.J. Hannon Argonaute2, a link between genetic and biochemical analyses of RNAi Science 293 2001 1146 1150
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 108
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • J.J. Song, S.K. Smith, G.J. Hannon, and L. Joshua-Tor Crystal structure of Argonaute and its implications for RISC slicer activity Science 305 2004 1434 1437
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 112
    • 77954214431 scopus 로고    scopus 로고
    • Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein
    • A. Boland, F. Tritschler, S. Heimstadt, E. Izaurralde, and O. Weichenrieder Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein EMBO Rep. 11 2010 522 527
    • (2010) EMBO Rep. , vol.11 , pp. 522-527
    • Boland, A.1    Tritschler, F.2    Heimstadt, S.3    Izaurralde, E.4    Weichenrieder, O.5
  • 113
    • 77953479619 scopus 로고    scopus 로고
    • Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2
    • F. Frank, N. Sonenberg, and B. Nagar Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2 Nature 465 2010 818 822
    • (2010) Nature , vol.465 , pp. 818-822
    • Frank, F.1    Sonenberg, N.2    Nagar, B.3
  • 114
    • 15844371219 scopus 로고    scopus 로고
    • Structural basis for 5'-end-specific recognition of guide RNA by the A fulgidus Piwi protein
    • J.B. Ma, Y.R. Yuan, G. Meister, Y. Pei, T. Tuschl, and D.J. Patel Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein Nature 434 2005 666 670
    • (2005) Nature , vol.434 , pp. 666-670
    • Ma, J.B.1    Yuan, Y.R.2    Meister, G.3    Pei, Y.4    Tuschl, T.5    Patel, D.J.6
  • 115
    • 15844402005 scopus 로고    scopus 로고
    • Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
    • J.S. Parker, S.M. Roe, and D. Barford Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex Nature 434 2005 663 666
    • (2005) Nature , vol.434 , pp. 663-666
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 116
    • 56249145105 scopus 로고    scopus 로고
    • Structure of the guide-strand-containing argonaute silencing complex
    • Y. Wang, G. Sheng, S. Juranek, T. Tuschl, and D.J. Patel Structure of the guide-strand-containing argonaute silencing complex Nature 456 2008 209 213
    • (2008) Nature , vol.456 , pp. 209-213
    • Wang, Y.1    Sheng, G.2    Juranek, S.3    Tuschl, T.4    Patel, D.J.5
  • 117
    • 0642345790 scopus 로고    scopus 로고
    • Structure and conserved RNA binding of the PAZ domain
    • K.S. Yan, S. Yan, A. Farooq, A. Han, L. Zeng, and M.M. Zhou Structure and conserved RNA binding of the PAZ domain Nature 426 2003 468 474
    • (2003) Nature , vol.426 , pp. 468-474
    • Yan, K.S.1    Yan, S.2    Farooq, A.3    Han, A.4    Zeng, L.5    Zhou, M.M.6
  • 118
    • 0345359925 scopus 로고    scopus 로고
    • Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain
    • A. Lingel, B. Simon, E. Izaurralde, and M. Sattler Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain Nature 426 2003 465 469
    • (2003) Nature , vol.426 , pp. 465-469
    • Lingel, A.1    Simon, B.2    Izaurralde, E.3    Sattler, M.4
  • 120
    • 2442679207 scopus 로고    scopus 로고
    • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
    • J.B. Ma, K. Ye, and D.J. Patel Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain Nature 429 2004 318 322
    • (2004) Nature , vol.429 , pp. 318-322
    • Ma, J.B.1    Ye, K.2    Patel, D.J.3
  • 124
    • 84861451595 scopus 로고    scopus 로고
    • The crystal structure of human Argonaute2
    • N.T. Schirle, and I.J. MacRae The crystal structure of human Argonaute2 Science 336 2012 1037 1040
    • (2012) Science , vol.336 , pp. 1037-1040
    • Schirle, N.T.1    Macrae, I.J.2
  • 128
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • G. Hutvagner, and P.D. Zamore A microRNA in a multiple-turnover RNAi enzyme complex Science 297 2002 2056 2060
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvagner, G.1    Zamore, P.D.2
  • 129
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • S.M. Elbashir, J. Martinez, A. Patkaniowska, W. Lendeckel, and T. Tuschl Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate EMBO J. 20 2001 6877 6888
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 130
    • 14644393684 scopus 로고    scopus 로고
    • Perspective: Machines for RNAi
    • Y. Tomari, and P.D. Zamore Perspective: machines for RNAi Genes Dev. 19 2005 517 529
    • (2005) Genes Dev. , vol.19 , pp. 517-529
    • Tomari, Y.1    Zamore, P.D.2
  • 131
    • 79251485649 scopus 로고    scopus 로고
    • Modifications of small RNAs and their associated proteins
    • Y.K. Kim, I. Heo, and V.N. Kim Modifications of small RNAs and their associated proteins Cell 143 2010 703 709
    • (2010) Cell , vol.143 , pp. 703-709
    • Kim, Y.K.1    Heo, I.2    Kim, V.N.3
  • 132
    • 54349104464 scopus 로고    scopus 로고
    • Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs
    • J.E. Babiarz, J.G. Ruby, Y. Wang, D.P. Bartel, and R. Blelloch Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs Genes Dev. 22 2008 2773 2785
    • (2008) Genes Dev. , vol.22 , pp. 2773-2785
    • Babiarz, J.E.1    Ruby, J.G.2    Wang, Y.3    Bartel, D.P.4    Blelloch, R.5
  • 134
    • 77953961505 scopus 로고    scopus 로고
    • Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription
    • S. Guang, A.F. Bochner, K.B. Burkhart, N. Burton, D.M. Pavelec, and S. Kennedy Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription Nature 465 2010 1097 1101
    • (2010) Nature , vol.465 , pp. 1097-1101
    • Guang, S.1    Bochner, A.F.2    Burkhart, K.B.3    Burton, N.4    Pavelec, D.M.5    Kennedy, S.6
  • 136
    • 83755183247 scopus 로고    scopus 로고
    • Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans
    • N.O. Burton, K.B. Burkhart, and S. Kennedy Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans Proc. Natl. Acad. Sci. USA 108 2011 19683 19688
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 19683-19688
    • Burton, N.O.1    Burkhart, K.B.2    Kennedy, S.3
  • 139
    • 84863631177 scopus 로고    scopus 로고
    • PiRNAs initiate an epigenetic memory of nonself RNA in the C elegans germline
    • M. Shirayama, M. Seth, H.C. Lee, W. Gu, T. Ishidate, D.J. Conte, and C.C. Mello piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline Cell 150 2012 65 77
    • (2012) Cell , vol.150 , pp. 65-77
    • Shirayama, M.1    Seth, M.2    Lee, H.C.3    Gu, W.4    Ishidate, T.5    Conte, D.J.6    Mello, C.C.7
  • 140
    • 84856239588 scopus 로고    scopus 로고
    • Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint
    • S.G. Gu, J. Pak, S. Guang, J.M. Maniar, S. Kennedy, and A. Fire Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint Nat. Genet. 44 2012 157 164
    • (2012) Nat. Genet. , vol.44 , pp. 157-164
    • Gu, S.G.1    Pak, J.2    Guang, S.3    Maniar, J.M.4    Kennedy, S.5    Fire, A.6
  • 141
    • 70149093944 scopus 로고    scopus 로고
    • Regulation of heterochromatin assembly on unpaired chromosomes during Caenorhabditis elegans meiosis by components of a small RNA-mediated pathway
    • X. She, X. Xu, A. Fedotov, W.G. Kelly, and E.M. Maine Regulation of heterochromatin assembly on unpaired chromosomes during Caenorhabditis elegans meiosis by components of a small RNA-mediated pathway PLoS Genet. 5 2009 e1000624
    • (2009) PLoS Genet. , vol.5 , pp. 1000624
    • She, X.1    Xu, X.2    Fedotov, A.3    Kelly, W.G.4    Maine, E.M.5
  • 146
    • 22144433672 scopus 로고    scopus 로고
    • A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes
    • L. Williams, C.C. Carles, K.S. Osmont, and J.C. Fletcher A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes Proc. Natl. Acad. Sci. USA 102 2005 9703 9708
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 9703-9708
    • Williams, L.1    Carles, C.C.2    Osmont, K.S.3    Fletcher, J.C.4
  • 147
    • 80053893642 scopus 로고    scopus 로고
    • Cell-to-cell and long-distance siRNA movement in plants: Mechanisms and biological implications
    • C.A. Brosnan, and O. Voinnet Cell-to-cell and long-distance siRNA movement in plants: mechanisms and biological implications Curr. Opin. Plant Biol. 14 2011 580 587
    • (2011) Curr. Opin. Plant Biol. , vol.14 , pp. 580-587
    • Brosnan, C.A.1    Voinnet, O.2
  • 148
    • 60149098474 scopus 로고    scopus 로고
    • Small RNAs as guardians of the genome
    • C.D. Malone, and G.J. Hannon Small RNAs as guardians of the genome Cell 136 2009 656 668
    • (2009) Cell , vol.136 , pp. 656-668
    • Malone, C.D.1    Hannon, G.J.2
  • 149
    • 33845741236 scopus 로고    scopus 로고
    • Drosophila rasiRNA pathway mutations disrupt embryonic axis specification through activation of an ATR/Chk2 DNA damage response
    • C. Klattenhoff, D.P. Bratu, N. McGinnis-Schultz, B.S. Koppetsch, H.A. Cook, and W.E. Theurkauf Drosophila rasiRNA pathway mutations disrupt embryonic axis specification through activation of an ATR/Chk2 DNA damage response Dev. Cell 12 2007 45 55
    • (2007) Dev. Cell , vol.12 , pp. 45-55
    • Klattenhoff, C.1    Bratu, D.P.2    McGinnis-Schultz, N.3    Koppetsch, B.S.4    Cook, H.A.5    Theurkauf, W.E.6
  • 155
    • 84872533627 scopus 로고    scopus 로고
    • RNA interference in the nucleus: Roles for small RNAs in transcription, epigenetics and beyond
    • S.E. Castel, and R.A. Martienssen RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond Nat. Rev. Genet. 14 2013 100 112
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 100-112
    • Castel, S.E.1    Martienssen, R.A.2
  • 156
    • 84887476086 scopus 로고    scopus 로고
    • Antiviral RNA interference in animals: Piecing together the evidence
    • M. Tanguy, and E.A. Miska Antiviral RNA interference in animals: piecing together the evidence Nat. Struct. Mol. Biol. 20 2013 1239 1241
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 1239-1241
    • Tanguy, M.1    Miska, E.A.2
  • 157
    • 77956170809 scopus 로고    scopus 로고
    • RNA-based antiviral immunity
    • S.W. Ding RNA-based antiviral immunity Nat. Rev. Immunol. 10 2010 632 644
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 632-644
    • Ding, S.W.1
  • 159
    • 0035807818 scopus 로고    scopus 로고
    • Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
    • E. Billy, V. Brondani, H. Zhang, U. Muller, and W. Filipowicz Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines Proc. Natl. Acad. Sci. USA 98 2001 14428 14433
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14428-14433
    • Billy, E.1    Brondani, V.2    Zhang, H.3    Muller, U.4    Filipowicz, W.5
  • 160
    • 84895749135 scopus 로고    scopus 로고
    • Distinct antiviral responses in pluripotent versus differentiated cells
    • J.M. Pare, and C.S. Sullivan Distinct antiviral responses in pluripotent versus differentiated cells PLoS Pathog. 10 2014 e1003865
    • (2014) PLoS Pathog. , vol.10 , pp. 1003865
    • Pare, J.M.1    Sullivan, C.S.2
  • 161
    • 53349121971 scopus 로고    scopus 로고
    • Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila
    • R. Aliyari, Q. Wu, H.W. Li, X.H. Wang, F. Li, L.D. Green, C.S. Han, W.X. Li, and S.W. Ding Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila Cell Host Microbe 4 2008 387 397
    • (2008) Cell Host Microbe , vol.4 , pp. 387-397
    • Aliyari, R.1    Wu, Q.2    Li, H.W.3    Wang, X.H.4    Li, F.5    Green, L.D.6    Han, C.S.7    Li, W.X.8    Ding, S.W.9
  • 162
    • 65249175123 scopus 로고    scopus 로고
    • Dicing of viral replication intermediates during silencing of latent Drosophila viruses
    • A. Flynt, N. Liu, R. Martin, and E.C. Lai Dicing of viral replication intermediates during silencing of latent Drosophila viruses Proc. Natl. Acad. Sci. USA 106 2009 5270 5275
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 5270-5275
    • Flynt, A.1    Liu, N.2    Martin, R.3    Lai, E.C.4
  • 163
    • 33751120715 scopus 로고    scopus 로고
    • The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster
    • R.P. van Rij, M.C. Saleh, B. Berry, C. Foo, A. Houk, C. Antoniewski, and R. Andino The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster Genes Dev. 20 2006 2985 2995
    • (2006) Genes Dev. , vol.20 , pp. 2985-2995
    • Van Rij, R.P.1    Saleh, M.C.2    Berry, B.3    Foo, C.4    Houk, A.5    Antoniewski, C.6    Andino, R.7
  • 164
    • 33744494279 scopus 로고    scopus 로고
    • Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila
    • D. Galiana-Arnoux, C. Dostert, A. Schneemann, J.A. Hoffmann, and J.L. Imler Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila Nat. Immunol. 7 2006 590 597
    • (2006) Nat. Immunol. , vol.7 , pp. 590-597
    • Galiana-Arnoux, D.1    Dostert, C.2    Schneemann, A.3    Hoffmann, J.A.4    Imler, J.L.5
  • 169
    • 84885635441 scopus 로고    scopus 로고
    • RNA interference functions as an antiviral immunity mechanism in mammals
    • Y. Li, J. Lu, Y. Han, X. Fan, and S.W. Ding RNA interference functions as an antiviral immunity mechanism in mammals Science 342 2013 231 234
    • (2013) Science , vol.342 , pp. 231-234
    • Li, Y.1    Lu, J.2    Han, Y.3    Fan, X.4    Ding, S.W.5
  • 171
    • 23944506789 scopus 로고    scopus 로고
    • Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans
    • R. Lu, M. Maduro, F. Li, H.W. Li, G. Broitman-Maduro, W.X. Li, and S.W. Ding Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans Nature 436 2005 1040 1043
    • (2005) Nature , vol.436 , pp. 1040-1043
    • Lu, R.1    Maduro, M.2    Li, F.3    Li, H.W.4    Broitman-Maduro, G.5    Li, W.X.6    Ding, S.W.7
  • 172
    • 61449248246 scopus 로고    scopus 로고
    • An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans
    • R. Lu, E. Yigit, W.X. Li, and S.W. Ding An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans PLoS Pathog. 5 2009 e1000286
    • (2009) PLoS Pathog. , vol.5 , pp. 1000286
    • Lu, R.1    Yigit, E.2    Li, W.X.3    Ding, S.W.4
  • 173
    • 83255184978 scopus 로고    scopus 로고
    • Transgenerational inheritance of an acquired small RNA-based antiviral response in C elegans
    • O. Rechavi, G. Minevich, and O. Hobert Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans Cell 147 2011 1248 1256
    • (2011) Cell , vol.147 , pp. 1248-1256
    • Rechavi, O.1    Minevich, G.2    Hobert, O.3
  • 174
    • 84885334266 scopus 로고    scopus 로고
    • A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity
    • A. Ashe, T. Belicard, J. Le Pen, P. Sarkies, L. Frezal, N.J. Lehrbach, M.A. Felix, and E.A. Miska A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity Elife 2 2013 e00994
    • (2013) Elife , vol.2 , pp. 00994
    • Ashe, A.1    Belicard, T.2    Le Pen, J.3    Sarkies, P.4    Frezal, L.5    Lehrbach, N.J.6    Felix, M.A.7    Miska, E.A.8
  • 178
    • 84863624978 scopus 로고    scopus 로고
    • C elegans piRNAs mediate the genome-wide surveillance of germline transcripts
    • H.C. Lee, W. Gu, M. Shirayama, E. Youngman, D.J. Conte, and C.C. Mello C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts Cell 150 2012 78 87
    • (2012) Cell , vol.150 , pp. 78-87
    • Lee, H.C.1    Gu, W.2    Shirayama, M.3    Youngman, E.4    Conte, D.J.5    Mello, C.C.6
  • 179
    • 84871593032 scopus 로고    scopus 로고
    • CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C elegans piRNA precursors
    • W. Gu, H.C. Lee, D. Chaves, E.M. Youngman, G.J. Pazour, D.J. Conte, and C.C. Mello CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors Cell 151 2012 1488 1500
    • (2012) Cell , vol.151 , pp. 1488-1500
    • Gu, W.1    Lee, H.C.2    Chaves, D.3    Youngman, E.M.4    Pazour, G.J.5    Conte, D.J.6    Mello, C.C.7
  • 180
    • 84890818459 scopus 로고    scopus 로고
    • The C elegans CSR-1 Argonaute pathway counteracts epigenetic silencing to promote germline gene expression
    • M. Seth, M. Shirayama, W. Gu, T. Ishidate, D.J. Conte, and C.C. Mello The C. elegans CSR-1 Argonaute pathway counteracts epigenetic silencing to promote germline gene expression Dev. Cell 27 2013 656 663
    • (2013) Dev. Cell , vol.27 , pp. 656-663
    • Seth, M.1    Shirayama, M.2    Gu, W.3    Ishidate, T.4    Conte, D.J.5    Mello, C.C.6
  • 181
    • 84890836064 scopus 로고    scopus 로고
    • Protection of germline gene expression by the C elegans Argonaute CSR-1
    • C.J. Wedeles, M.Z. Wu, and J.M. Claycomb Protection of germline gene expression by the C. elegans Argonaute CSR-1 Dev. Cell 27 2013 664 671
    • (2013) Dev. Cell , vol.27 , pp. 664-671
    • Wedeles, C.J.1    Wu, M.Z.2    Claycomb, J.M.3
  • 183
    • 33947262696 scopus 로고    scopus 로고
    • AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2
    • S. Vasudevan, and J.A. Steitz AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2 Cell 128 2007 1105 1118
    • (2007) Cell , vol.128 , pp. 1105-1118
    • Vasudevan, S.1    Steitz, J.A.2
  • 184
    • 36048937264 scopus 로고    scopus 로고
    • An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster
    • H. Yin, and H. Lin An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster Nature 450 2007 304 308
    • (2007) Nature , vol.450 , pp. 304-308
    • Yin, H.1    Lin, H.2
  • 185
  • 187
    • 84896879856 scopus 로고    scopus 로고
    • Small but sturdy: Small RNAs in cellular memory and epigenetics
    • E. Stuwe, K.F. Toth, and A.A. Aravin Small but sturdy: small RNAs in cellular memory and epigenetics Genes Dev. 28 2014 423 431
    • (2014) Genes Dev. , vol.28 , pp. 423-431
    • Stuwe, E.1    Toth, K.F.2    Aravin, A.A.3
  • 190
    • 36749037521 scopus 로고    scopus 로고
    • The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race
    • A.A. Aravin, G.J. Hannon, and J. Brennecke The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race Science 318 2007 761 764
    • (2007) Science , vol.318 , pp. 761-764
    • Aravin, A.A.1    Hannon, G.J.2    Brennecke, J.3
  • 193
    • 84892974070 scopus 로고    scopus 로고
    • Small RNAs and heritable epigenetic variation in plants
    • D.M. Bond, and D.C. Baulcombe Small RNAs and heritable epigenetic variation in plants Trends Cell Biol. 24 2014 100 107
    • (2014) Trends Cell Biol. , vol.24 , pp. 100-107
    • Bond, D.M.1    Baulcombe, D.C.2
  • 194
    • 33646885228 scopus 로고    scopus 로고
    • Arabidopsis displays centromeric DNA hypomethylation and cytological alterations of heterochromatin upon attack by pseudomonas syringae
    • V. Pavet, C. Quintero, N.M. Cecchini, A.L. Rosa, and M.E. Alvarez Arabidopsis displays centromeric DNA hypomethylation and cytological alterations of heterochromatin upon attack by pseudomonas syringae Mol. Plant Microbe Interact. 19 2006 577 587
    • (2006) Mol. Plant Microbe Interact. , vol.19 , pp. 577-587
    • Pavet, V.1    Quintero, C.2    Cecchini, N.M.3    Rosa, A.L.4    Alvarez, M.E.5
  • 196
    • 84856565990 scopus 로고    scopus 로고
    • Descendants of primed Arabidopsis plants exhibit resistance to biotic stress
    • A. Slaughter, X. Daniel, V. Flors, E. Luna, B. Hohn, and B. Mauch-Mani Descendants of primed Arabidopsis plants exhibit resistance to biotic stress Plant Physiol. 158 2012 835 843
    • (2012) Plant Physiol. , vol.158 , pp. 835-843
    • Slaughter, A.1    Daniel, X.2    Flors, V.3    Luna, E.4    Hohn, B.5    Mauch-Mani, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.