RNAi in budding yeast

Science

Volumn 326, Issue 5952, 2009, Pages 544-550

  Drinnenberg, Ines A ^a,b   Weinberg, David E ^a,b   Xie, Kathleen T ^a,b   Mower, Jeffrey P ^c,d   Wolfe, Kenneth H ^c   Fink, Gerald R ^a,b   Bartel, David P ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; DICER; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTOME;

EUKARYOTE; GENE EXPRESSION; MUTATION; PROTEIN; RNA; SPECIES DIVERSITY; YEAST;

ARTICLE; CANDIDA ALBICANS; CHEMICAL ANALYSIS; ENZYME RECONSTITUTION; GENE CONSTRUCT; GENE SILENCING; MUTANT; NONHUMAN; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROTEIN DETERMINATION; RETROPOSON; RNA INTERFERENCE; SACCHAROMYCES CASTELLI; TELOMERE; TRANSPOSON; YEAST;

FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENES, FUNGAL; GENETIC LOCI; MUTATION; OPEN READING FRAMES; REPETITIVE SEQUENCES, NUCLEIC ACID; RETROELEMENTS; RIBONUCLEASE III; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, FUNGAL; RNA, MESSENGER; RNA, SMALL INTERFERING; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SACCHAROMYCETALES; SEQUENCE ANALYSIS, RNA; TRANSCRIPTION, GENETIC; TRANSFORMATION, GENETIC;

CANDIDA ALBICANS; EUKARYOTA; SACCHAROMYCES CASTELLII; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 70350510820     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1176945     Document Type: Article

References (40)

1. Y. Tomari, P. D. Zamore, Genes Dev. 19, 517 (2005).
2. C. D. Malone, G. J. Hannon, Cell 136, 656 (2009).
3. T. A. Farazi, S. A. Juranek, T. Tuschl, Development 135, 1201 (2008).
4. H. Nakayashiki, N. Kadotani, S. Mayama, J. Mol. Evol. 63, 127 (2006).
5. J. D. Laurie, R. Linning, G. Bakkeren, Curr. Genet. 53, 49 (2008).
6. D. R. Scannell et al., Proc. Natl. Acad. Sei. U.S.A. 104, 8397 (2007).
7. M. Axelson-Fisk, P. Sunnerhagen, Comparative Genomics: Using Fungi as Models (Topics in Current Genetics, Springer, Heidelberg, Germany, vol. 15, 2006), pp. 1-28.
8. J. Berman, P. E. Sudbery, Nat. Rev. Genet. 3, 918 (2002).
9. T. M. Hall, Structure 13, 1403 (2005).
10. A. Grimson et al., Nature 455, 1193 (2008).
11. N. C. Lau, L. P. Lim, E. G. Weinstein, D. P. Bartel, Science 294, 858 (2001).
12. T. A. Montgomery et al., Cell 133, 128 (2008).
13. M. Buhler, N. Spies, D. P. Bartel, D. Moazed, Nat. Struct. Mol. Biol. 15, 1015 (2008).
14. S. I. Grewal, S. Jia, Nat. Rev. Genet. 8, 35 (2007).
15. Materials and methods are available as supporting material on Science Online.
16. B. Lamontagne, S. Larose, J. Boulanger, S. A. Elela, Curr. Issues Mol. Biol. 3, 71 (2001).
17. E. Astromskas, M. Cohn, Yeast 24, 499 (2007).
18. E. Bernstein, A. A. Caudy, S. M. Hammond, G. J. Hannon, Nature 409, 363 (2001).
19. I. J. MacRae, J. A. Doudna, Curr. Opin. Struct. Biol. 17, 138 (2007).
20. H. Zhang, F. A. Kolb, L. Jaskiewicz, E. Westhof, W. Filipowicz, Cell 118, 57 (2004).
21. Q. Liu et al., Science 301, 1921 (2003).
22. F. Vazquez, V. Gasciolli, P. Crete, H. Vaucheret, Curr. Biol. 14, 346 (2004).
23. T. P. Chendrimada et al., Nature 436, 740 (2005).
24. R. Lister et al., Cell 133, 523 (2008).
25. E. J. Louis, J. E. Haber, Genetics 131, 559 (1992).
26. K. P. Byrne, K. H. Wolfe, Genome Res. 15, 1456 (2005).
27. U. Nagalakshmi et al., Science 320, 1344 (2008).
28. Y. Tomari, C. Matranga, B. Haley, N. Martinez, P. D. Zamore, Science 306,1377 (2004).
29. M. Maiti, H. C. Lee, Y. Liu, Genes Dev. 21, 590 (2007).
30. J. Berretta, M. Pinskaya, A. Morillon, Genes Dev. 22, 615 (2008).
31. J. M. Kim, S. Vanguri, J. D. Boeke, A. Gabriel, D. F. Voytas, Genome Res. 8, 464 (1998).
32. N. T. Ingolia, S. Ghaemmaghami, J. R. S. Newman, J. S. Weissman, Science 324, 218 (2009).
33. D. J. Garfinkel, M. F. Mastrangelo, N. J. Sanders, B. K. Shafer, J. N. Strathern, Genetics 120, 95 (1988).
34. R. B. Wickner, Microbiol. Rev. 60, 250 (1996).
35. S. M. Hedtke, T. M. Townsend, D. M. Hillis, Syst. Biol. 55, 522 (2006).
36. D. A. Fitzpatrick, M. E. Logue, J. E. Stajich, G. Butler, BMC Evol. Biol. 6, 99 (2006).
37. M. Zuker, P. Stiegler, Nucleic Acids Res. 9, 133 (1981).
38. A. Sigova, N. Rhind, P. D. Zamore, Cenes Dev. 18, 2359 (2004).
39. K. Kawakami et al., Genetics 135, 309 (1993).
40. We thank A. Hochwagen, G. Ruby, and H. Guo for helpful discussions; V. Agarwal for protein homology modeling; D. Garfinkel for Ty1-VLP antiserum and other reagents; M. Cohn and A. Regev for yeast strains; W. Johnston and the Whitehead Genome Technology Core for high-throughput sequencing; and S. Pääbo for academic advising. Supported by Science Foundation Ireland and the Irish Research Council for Science, Engineering, and Technology (K.H.W.), NIH grants GM040266 (G.R.F.), GM0305010 (G.R.F.), and GM067031 (D.P.B.), an NSF graduate research fellowship (D.E.W.), and a Boehringer-lngelheim Fonds predoctoral fellowship (I.A.D.). D.P.B. is an Investigator of the Howard Hughes Medical Institute. The Gene Expression Omnibus accession number for all the mRNA-Seq and small-RNA cloning data is GSE17872.