-
1
-
-
84878240136
-
Molecular regulation of stem cell quiescence
-
(doi:10.1038/nrm3591)
-
Cheung TH, Rando TA. 2013 Molecular regulation of stem cell quiescence. Nat. Rev. Mol. Cell Biol. 14, 329-340. (doi:10.1038/nrm3591)
-
(2013)
Nat. Rev. Mol. Cell Biol
, vol.14
, pp. 329-340
-
-
Cheung, T.H.1
Rando, T.A.2
-
2
-
-
84866409581
-
Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity
-
(doi:10. 1091/mbc.E12-03-0192)
-
Legesse-Miller A et al. 2012 Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity. Mol. Biol. Cell 23, 3566-3581. (doi:10. 1091/mbc.E12-03-0192)
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 3566-3581
-
-
Legesse-Miller, A.1
-
3
-
-
33644984490
-
A new description of cellular quiescence
-
(doi:10.1371/journal.pbio.0040083)
-
Coller HA, Sang L, Roberts JM. 2006 A new description of cellular quiescence. PLoS Biol. 4, e83. (doi:10.1371/journal.pbio.0040083)
-
(2006)
PLoS Biol
, vol.4
-
-
Coller, H.A.1
Sang, L.2
Roberts, J.M.3
-
4
-
-
34347341782
-
A transcriptional program mediating entry into cellular quiescence
-
(doi:10.1371/journal.pgen.0030091)
-
Liu H, Adler AS, Segal E, Chang HY. 2007 A transcriptional program mediating entry into cellular quiescence. PLoS Genet. 3, 996-1008. (doi:10.1371/journal.pgen.0030091)
-
(2007)
PLoS Genet
, vol.3
, pp. 996-1008
-
-
Liu, H.1
Adler, A.S.2
Segal, E.3
Chang, H.Y.4
-
5
-
-
0038644122
-
Regulation of quiescence in lymphocytes
-
(doi:10.1016/S1471-4906(03)00141-8)
-
Yusuf I, Fruman DA. 2003 Regulation of quiescence in lymphocytes. Trends Immunol. 24, 380-386. (doi:10.1016/S1471-4906(03)00141-8)
-
(2003)
Trends Immunol
, vol.24
, pp. 380-386
-
-
Yusuf, I.1
Fruman, D.A.2
-
6
-
-
8844250116
-
Molecular signatures of proliferation and quiescence in hematopoietic stem cells
-
(doi:10.1371/journal.pbio.0020301)
-
Venezia TA, Merchant AA, Ramos CA, Whitehouse NL, Young AS, Shaw CA, Goodell MA. 2004 Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2, e301. (doi:10.1371/journal.pbio.0020301)
-
(2004)
PLoS Biol
, vol.2
-
-
Venezia, T.A.1
Merchant, A.A.2
Ramos, C.A.3
Whitehouse, N.L.4
Young, A.S.5
Shaw, C.A.6
Goodell, M.A.7
-
7
-
-
50149117285
-
Control of the reversibility of cellular quiescence by the transcriptional repressor HES1
-
(doi:10.1126/science.1155998)
-
Sang L, Coller HA, Roberts JM. 2008 Control of the reversibility of cellular quiescence by the transcriptional repressor HES1. Science 321, 1095-1100. (doi:10.1126/science.1155998)
-
(2008)
Science
, vol.321
, pp. 1095-1100
-
-
Sang, L.1
Coller, H.A.2
Roberts, J.M.3
-
8
-
-
78149378853
-
Quiescent fibroblasts exhibit high metabolic activity
-
(doi:10.1371/journal.pbio.1000514)
-
Lemons JMS et al. 2010 Quiescent fibroblasts exhibit high metabolic activity. PLoS Biol. 8, e1000514. (doi:10.1371/journal.pbio.1000514)
-
(2010)
PLoS Biol
, vol.8
-
-
Lemons, J.M.S.1
-
9
-
-
84860778451
-
Staying alive: Metabolic adaptations to quiescence
-
(doi:10.4161/cc.19879)
-
Valcourt JR, Lemons JMS, Haley EM, Kojima M, Demuren OO, Coller HA. 2012 Staying alive: metabolic adaptations to quiescence. Cell Cycle 11, 1680-1696. (doi:10.4161/cc.19879)
-
(2012)
Cell Cycle
, vol.11
, pp. 1680-1696
-
-
Valcourt, J.R.1
Lemons, J.M.S.2
Haley, E.M.3
Kojima, M.4
Demuren, O.O.5
Coller, H.A.6
-
10
-
-
0015136814
-
Stimulation by serum of multiplication of stationary chicken cells
-
(doi:10.1002/jcp. 1040780202)
-
Temin HM. 1971 Stimulation by serum of multiplication of stationary chicken cells. J. Cell. Physiol. 78, 161-170. (doi:10.1002/jcp. 1040780202)
-
(1971)
J. Cell. Physiol
, vol.78
, pp. 161-170
-
-
Temin, H.M.1
-
11
-
-
0015411488
-
Transport changes in synchronously growing CHO and L cells
-
(doi:10.1002/jcp. 1040800214)
-
Sander G, Pardee AB. 1972 Transport changes in synchronously growing CHO and L cells. J. Cell. Physiol. 80, 267-271. (doi:10.1002/jcp. 1040800214)
-
(1972)
J. Cell. Physiol
, vol.80
, pp. 267-271
-
-
Sander, G.1
Pardee, A.B.2
-
12
-
-
0015939583
-
Effect of nutritional changes on chromatin template activity and non-histone chromosomal protein-synthesis in Wi-38 and 3t6 cells
-
(doi:10.1016/0014-4827(73)90045-1)
-
Rovera G, Baserga R. 1973 Effect of nutritional changes on chromatin template activity and non-histone chromosomal protein-synthesis in Wi-38 and 3t6 cells. Exp. Cell Res. 78, 118-126. (doi:10.1016/0014-4827(73)90045-1)
-
(1973)
Exp. Cell Res
, vol.78
, pp. 118-126
-
-
Rovera, G.1
Baserga, R.2
-
14
-
-
0016144499
-
Changes in the G0 state of WI-38 fibroblasts at different times after confluence
-
(doi:10. 1016/0014-4827(74)90789-7)
-
Augenlicht LH, Baserga R. 1974 Changes in the G0 state of WI-38 fibroblasts at different times after confluence. Exp. Cell Res. 89, 255-262. (doi:10. 1016/0014-4827(74)90789-7)
-
(1974)
Exp. Cell Res
, vol.89
, pp. 255-262
-
-
Augenlicht, L.H.1
Baserga, R.2
-
15
-
-
0028183271
-
WI-38 cell long-term quiescence model system: A valuable tool to study molecular events that regulate growth
-
(doi:10.1002/jcb.240540407)
-
Soprano KJ. 1994 WI-38 cell long-term quiescence model system: a valuable tool to study molecular events that regulate growth. J. Cell Biochem. 54, 405-414. (doi:10.1002/jcb.240540407)
-
(1994)
J. Cell Biochem
, vol.54
, pp. 405-414
-
-
Soprano, K.J.1
-
16
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
(doi:10.1073/pnas. 71.4.1286)
-
Pardee AB. 1974 A restriction point for control of normal animal cell proliferation. Proc. Natl Acad. Sci. USA, 71, 1286-1290. (doi:10.1073/pnas. 71.4.1286)
-
(1974)
Proc. Natl Acad. Sci. USA
, vol.71
, pp. 1286-1290
-
-
Pardee, A.B.1
-
17
-
-
0021855166
-
Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells
-
(doi:10.1073/pnas.82.16.5365)
-
Zetterberg A, Larsson O. 1985 Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc. Natl Acad. Sci. USA 82, 5365-5369. (doi:10.1073/pnas.82.16.5365)
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 5365-5369
-
-
Zetterberg, A.1
Larsson, O.2
-
18
-
-
0023440741
-
On G0 and cell cycle controls
-
(doi:10.1002/bies. 950070507)
-
Cooper S. 1987 On G0 and cell cycle controls. Bioessays 7, 220-223. (doi:10.1002/bies. 950070507)
-
(1987)
Bioessays
, vol.7
, pp. 220-223
-
-
Cooper, S.1
-
19
-
-
0037337879
-
Reappraisal of serum starvation, the restriction point, G0, and G1 phase arrest points
-
(doi:10.1096/fj.02-0352rev)
-
Cooper S. 2003 Reappraisal of serum starvation, the restriction point, G0, and G1 phase arrest points. Faseb J. 17, 333-340. (doi:10.1096/fj.02-0352rev)
-
(2003)
Faseb J
, vol.17
, pp. 333-340
-
-
Cooper, S.1
-
20
-
-
82255169482
-
Cell biology. The essence of quiescence
-
(doi:10.1126/ science.1216242)
-
Coller HA. 2011 Cell biology. The essence of quiescence. Science 334, 1074-1075. (doi:10.1126/ science.1216242)
-
(2011)
Science
, vol.334
, pp. 1074-1075
-
-
Coller, H.A.1
-
21
-
-
34547108336
-
What's taking so long? S-phase entry from quiescence versus proliferation
-
(doi:10.1038/nrm2223)
-
Coller HA. 2007 What's taking so long? S-phase entry from quiescence versus proliferation. Nat. Rev. Mol. Cell Biol. 8, 667-670. (doi:10.1038/nrm2223)
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 667-670
-
-
Coller, H.A.1
-
23
-
-
0015609842
-
Do cells cycle
-
(doi:10.1073/pnas. 70.4.1263)
-
Smith JA, Martin L. 1973 Do cells cycle. Proc. Natl Acad. Sci. USA 70, 1263-1267. (doi:10.1073/pnas. 70.4.1263)
-
(1973)
Proc. Natl Acad. Sci. USA
, vol.70
, pp. 1263-1267
-
-
Smith, J.A.1
Martin, L.2
-
24
-
-
0016409381
-
Some properties of a G0 model of cell-cycle investigation on possible existence of natural constraints on theoretical model in steady-state conditions
-
Demaertelaer V, Galand P. 1975 Some properties of a G0 model of cell-cycle investigation on possible existence of natural constraints on theoretical model in steady-state conditions. Cell Tissue Kinetics 8, 11-22.
-
(1975)
Cell Tissue Kinetics
, vol.8
, pp. 11-22
-
-
Demaertelaer, V.1
Galand, P.2
-
25
-
-
0017377883
-
Cells regulate their proliferation through alterations in transition-probability
-
(doi:10. 1002/jcp.1040910304)
-
Shields R, Smith JA. 1977 Cells regulate their proliferation through alterations in transition-probability. J. Cell. Physiol. 91, 345-355. (doi:10. 1002/jcp.1040910304)
-
(1977)
J. Cell. Physiol
, vol.91
, pp. 345-355
-
-
Shields, R.1
Smith, J.A.2
-
26
-
-
0018891216
-
Mammalian cell cycles need two random transitions
-
(doi:10.1016/0092-8674(80)90524-3)
-
Brooks RF, Bennett DC, Smith JA. 1980 Mammalian cell cycles need two random transitions. Cell 19, 493-504. (doi:10.1016/0092-8674(80)90524-3)
-
(1980)
Cell
, vol.19
, pp. 493-504
-
-
Brooks, R.F.1
Bennett, D.C.2
Smith, J.A.3
-
27
-
-
0018818720
-
Does the variability of the cell-cycle result from one or many chance events
-
(doi:10.1038/286080a0)
-
Koch AL. 1980 Does the variability of the cell-cycle result from one or many chance events. Nature 286, 80-82. (doi:10.1038/286080a0)
-
(1980)
Nature
, vol.286
, pp. 80-82
-
-
Koch, A.L.1
-
28
-
-
0019226550
-
A G1 rate model accounts for cell-cycle kinetics attributed to transition-probability
-
(doi:10.1038/287857a0)
-
Castor LN. 1980 A G1 rate model accounts for cell-cycle kinetics attributed to transition-probability. Nature 287, 857-859. (doi:10.1038/287857a0)
-
(1980)
Nature
, vol.287
, pp. 857-859
-
-
Castor, L.N.1
-
29
-
-
0020048204
-
The continuum model-statistical implications
-
(doi:10. 1016/0022-5193(82)90078-9)
-
Cooper S. 1982 The continuum model-statistical implications. J. Theor. Biol. 94, 783-800. (doi:10. 1016/0022-5193(82)90078-9)
-
(1982)
J. Theor. Biol
, vol.94
, pp. 783-800
-
-
Cooper, S.1
-
30
-
-
0022385786
-
The distributions of cell size and generation time in a model of the cell cycle incorporating size control and random transitions
-
(doi:10. 1016/S0022-5193(85)80074-6)
-
Tyson JJ, Hannsgen KB. 1985 The distributions of cell size and generation time in a model of the cell cycle incorporating size control and random transitions. J. Theor. Biol. 113, 29-62. (doi:10. 1016/S0022-5193(85)80074-6)
-
(1985)
J. Theor. Biol
, vol.113
, pp. 29-62
-
-
Tyson, J.J.1
Hannsgen, K.B.2
-
31
-
-
0023031739
-
Sloppy size control of the cell-division cycle
-
(doi:10.1016/S0022-5193(86)80162-X)
-
Tyson JJ, Diekmann O. 1986 Sloppy size control of the cell-division cycle. J. Theor. Biol. 118, 405-426. (doi:10.1016/S0022-5193(86)80162-X)
-
(1986)
J. Theor. Biol
, vol.118
, pp. 405-426
-
-
Tyson, J.J.1
Diekmann, O.2
-
32
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
(doi:10.1038/323643a0)
-
Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP. 1986 A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323, 643-646. (doi:10.1038/323643a0)
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogelj, S.3
Weinberg, R.A.4
Rapaport, J.M.5
Albert, D.M.6
Dryja, T.P.7
-
33
-
-
18344383345
-
Pocket proteins and cell cycle control
-
(doi:10.1038/sj. onc.1208619)
-
Cobrinik D. 2005 Pocket proteins and cell cycle control. Oncogene 24, 2796-2809. (doi:10.1038/sj. onc.1208619)
-
(2005)
Oncogene
, vol.24
, pp. 2796-2809
-
-
Cobrinik, D.1
-
34
-
-
11244276992
-
The E2F family: Specific functions and overlapping interests
-
(doi:10.1038/sj. emboj.7600481)
-
Attwooll C, Lazzerini Denchi E, Helin K. 2004 The E2F family: specific functions and overlapping interests. EMBO J. 23, 4709-4716. (doi:10.1038/sj. emboj.7600481)
-
(2004)
EMBO J
, vol.23
, pp. 4709-4716
-
-
Attwooll, C.1
Lazzerini, D.E.2
Helin, K.3
-
35
-
-
0037023755
-
Signaling networks that link cell proliferation and cell fate
-
(doi:10.1074/jbc.R10006 3200)
-
Sears RC, Nevins JR. 2002 Signaling networks that link cell proliferation and cell fate. J. Biol. Chem. 277, 11 617-11 620. (doi:10.1074/jbc.R10006 3200)
-
(2002)
J. Biol. Chem
, vol.2
, pp. 11617-11620
-
-
Sears, R.C.1
Nevins, J.R.2
-
36
-
-
2942722811
-
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
-
(doi:10. 1242/jcs.01227)
-
Frolov MV, Dyson NJ. 2004 Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell Sci. 117, 2173-2181. (doi:10. 1242/jcs.01227)
-
(2004)
J. Cell Sci
, vol.117
, pp. 2173-2181
-
-
Frolov, M.V.1
Dyson, N.J.2
-
37
-
-
33750920705
-
Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
-
DeGregori J, Johnson DG. 2006 Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr. Mol. Med. 6, 739-748.
-
(2006)
Curr. Mol. Med
, vol.6
, pp. 739-748
-
-
Degregori, J.1
Johnson, D.G.2
-
38
-
-
33748084700
-
Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes
-
(doi:10.1038/sj.onc.1209680)
-
Macaluso M, Montanari M, Giordano A. 2006 Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes. Oncogene 25, 5263-5267. (doi:10.1038/sj.onc.1209680)
-
(2006)
Oncogene
, vol.25
, pp. 5263-5267
-
-
Macaluso, M.1
Montanari, M.2
Giordano, A.3
-
39
-
-
0034811677
-
Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase
-
(doi:10.1128/MCB.21.19.6484-6494. 2001)
-
Vandel L, Nicolas E, Vaute O, Ferreira R, Ait-Si-Ali S, Trouche D. 2001 Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase. Mol. Cell. Biol. 21, 6484-6494. (doi:10.1128/MCB.21.19.6484-6494. 2001)
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 6484-6494
-
-
Vandel, L.1
Nicolas, E.2
Vaute, O.3
Ferreira, R.4
Ait-Si-Ali, S.5
Trouche, D.6
-
40
-
-
0035797384
-
Rb targets histone H3 methylation and HP1 to promoters
-
(doi:10.1038/35087620)
-
Nielsen SJ et al. 2001 Rb targets histone H3 methylation and HP1 to promoters. Nature 412, 561-565. (doi:10.1038/35087620)
-
(2001)
Nature
, vol.412
, pp. 561-565
-
-
Nielsen, S.J.1
-
41
-
-
34249048369
-
L3MBTL1, a histone-methylation-dependent chromatin lock
-
(doi:10.1016/j.cell.2007.03.048)
-
Trojer P et al. 2007 L3MBTL1, a histone-methylation-dependent chromatin lock. Cell 129, 915-928. (doi:10.1016/j.cell.2007.03.048)
-
(2007)
Cell
, vol.129
, pp. 915-928
-
-
Trojer, P.1
-
42
-
-
34249109173
-
Evolutionary conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
-
(doi:10.1016/j. molcel.2007.04.015)
-
Litovchick L et al. 2007 Evolutionary conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. Mol. Cell 26, 539-551. (doi:10.1016/j. molcel.2007.04.015)
-
(2007)
Mol. Cell
, vol.26
, pp. 539-551
-
-
Litovchick, L.1
-
43
-
-
0029909272
-
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state
-
Smith EJ, Leone G, DeGregori J, Jakoi L, Nevins JR. 1996 The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. Mol. Cell. Biol. 16,6965-6976.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 6965-6976
-
-
Smith, E.J.1
Leone, G.2
Degregori, J.3
Jakoi, L.4
Nevins, J.R.5
-
44
-
-
47049087588
-
A role for Myc in facilitating transcription activation by E2F1
-
(doi:10.1038/onc.2008.55)
-
Leung JY, Ehmann GL, Giangrande PH, Nevins JR. 2008 A role for Myc in facilitating transcription activation by E2F1. Oncogene 27, 4172-4179. (doi:10.1038/onc.2008.55)
-
(2008)
Oncogene
, vol.27
, pp. 4172-4179
-
-
Leung, J.Y.1
Ehmann, G.L.2
Giangrande, P.H.3
Nevins, J.R.4
-
45
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44(MAPK) and negatively by the p38/HOG(MAPK) pathway
-
(doi:10.1074/jbc.271.34.20608)
-
Lavoie JN, L'Allemain G, Brunet A, Muller R, Pouyssegur J. 1996 Cyclin D1 expression is regulated positively by the p42/p44(MAPK) and negatively by the p38/HOG(MAPK) pathway. J. Biol. Chem. 271, 20 608-20 616. (doi:10.1074/jbc.271.34.20608)
-
(1996)
J. Biol. Chem
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
46
-
-
0030989155
-
Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1
-
Aktas H, Cai H, Cooper GM. 1997 Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1. Mol. Cell. Biol. 17, 3850-3857.
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 3850-3857
-
-
Aktas, H.1
Cai, H.2
Cooper, G.M.3
-
47
-
-
0030901947
-
Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1
-
Kerkhoff E, Rapp UR. 1997 Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1. Mol. Cell. Biol. 17, 2576-2586.
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 2576-2586
-
-
Kerkhoff, E.1
Rapp, U.R.2
-
48
-
-
0032477854
-
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase (MEK1)
-
(doi:10.1073/pnas.95.3.1091)
-
Cheng M, Sexl V, Sherr CJ, Roussel MF. 1998 Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase (MEK1). Proc. Natl Acad. Sci. USA 95, 1091-1096. (doi:10.1073/pnas.95.3.1091)
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 1091-1096
-
-
Cheng, M.1
Sexl, V.2
Sherr, C.J.3
Roussel, M.F.4
-
49
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
-
(doi:10.1016/S0092-8674(00)81519-6)
-
Harbour JW, Luo RX, Santi AD, Postigo AA, Dean DC. 1999 Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. Cell 98, 859-869. (doi:10.1016/S0092-8674(00)81519-6)
-
(1999)
Cell
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
Luo, R.X.2
Santi, A.D.3
Postigo, A.A.4
Dean, D.C.5
-
50
-
-
0035936113
-
The E2F1-3 transcription factors are essential for cellular proliferation
-
(doi:10.1038/35106593)
-
Wu L et al. 2001 The E2F1-3 transcription factors are essential for cellular proliferation. Nature 414, 457-462. (doi:10.1038/35106593)
-
(2001)
Nature
, vol.414
, pp. 457-462
-
-
Wu, L.1
-
51
-
-
0027491775
-
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
-
(doi:10.1038/365349a0)
-
Johnson DG, Schwarz JK, Cress WD, Nevins JR. 1993 Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 365, 349-352. (doi:10.1038/365349a0)
-
(1993)
Nature
, vol.365
, pp. 349-352
-
-
Johnson, D.G.1
Schwarz, J.K.2
Cress, W.D.3
Nevins, J.R.4
-
52
-
-
0035063183
-
The Rb/E2F pathway and cancer
-
(doi:10.1093/hmg/ 10.7.699)
-
Nevins JR. 2001 The Rb/E2F pathway and cancer. Hum. Mol. Genet. 10, 699-703. (doi:10.1093/hmg/ 10.7.699)
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 699-703
-
-
Nevins, J.R.1
-
53
-
-
0031741554
-
Regulation of exit from quiescence by p27 and cyclin D1-CDK4
-
Ladha MH, Lee KY, Upton TM, Reed MF, Ewen ME. 1998 Regulation of exit from quiescence by p27 and cyclin D1-CDK4. Mol. Cell. Biol. 18, 6605-6615.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 6605-6615
-
-
Ladha, M.H.1
Lee, K.Y.2
Upton, T.M.3
Reed, M.F.4
Ewen, M.E.5
-
54
-
-
0141640830
-
Progression through the G(1)-phase of the on-going cell cycle
-
(doi:10.1002/jcb.10617)
-
Boonstra J. 2003 Progression through the G(1)-phase of the on-going cell cycle. J. Cell. Biochem. 90, 244-252. (doi:10.1002/jcb.10617)
-
(2003)
J. Cell. Biochem
, vol.90
, pp. 244-252
-
-
Boonstra, J.1
-
55
-
-
33947271294
-
Critical requirement for cell cycle inhibitors in sustaining nonproliferative states
-
(doi:10.1083/jcb. 200608109)
-
Pajalunga D, Mazzola A, Salzano AM, Biferi MG, De Luca G, Crescenzi M. 2007 Critical requirement for cell cycle inhibitors in sustaining nonproliferative states. J. Cell Biol. 176, 807-818. (doi:10.1083/jcb. 200608109)
-
(2007)
J. Cell Biol
, vol.176
, pp. 807-818
-
-
Pajalunga, D.1
Mazzola, A.2
Salzano, A.M.3
Biferi, M.G.4
de Luca, G.5
Crescenzi, M.6
-
56
-
-
84885614963
-
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit
-
(doi:10.1016/j.cell. 2013.08.062)
-
Spencer SL, Cappell SD, Tsai F-C, Overton KW, Wang CL, Meyer T. 2013 The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit. Cell 155, 369-383. (doi:10.1016/j.cell. 2013.08.062)
-
(2013)
Cell
, vol.155
, pp. 369-383
-
-
Spencer, S.L.1
Cappell, S.D.2
Tsai, F.-C.3
Overton, K.W.4
Wang, C.L.5
Meyer, T.6
-
57
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
(doi:10.1126/science.287.5459.1804)
-
Cheng T, Rodrigues N, Shen H, Yang Y, Dombkowski D, Sykes M. 2000 Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287, 1804-1808. (doi:10.1126/science.287.5459.1804)
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
Yang, Y.4
Dombkowski, D.5
Sykes, M.6
-
58
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
(doi:10.1101/gad.9.10.1149)
-
Sherr CJ, Roberts JM. 1995 Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163. (doi:10.1101/gad.9.10.1149)
-
(1995)
Genes Dev
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
59
-
-
0029664461
-
Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle
-
(doi:10.1126/science.272.5263.877)
-
Coats S, Flanagan WM, Nourse J, Roberts JM. 1996 Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science 272, 877-880. (doi:10.1126/science.272.5263.877)
-
(1996)
Science
, vol.272
, pp. 877-880
-
-
Coats, S.1
Flanagan, W.M.2
Nourse, J.3
Roberts, J.M.4
-
60
-
-
0002070843
-
The p130 pocket protein: Keeping order at cell cycle exit/re-entrance transitions
-
Mayol X, Grana X. 1998 The p130 pocket protein: keeping order at cell cycle exit/re-entrance transitions. Front. Biosci. 3, d11-d24.
-
(1998)
Front. Biosci
, vol.3
-
-
Mayol, X.1
Grana, X.2
-
61
-
-
0036897835
-
A revised picture of the E2F transcriptional network and RB function
-
(doi:10.1016/S0955-0674(02)00388-5)
-
Stevaux O, Dyson NJ. 2002 A revised picture of the E2F transcriptional network and RB function. Curr. Opin. Cell Biol. 14, 684-691. (doi:10.1016/S0955-0674(02)00388-5)
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 684-691
-
-
Stevaux, O.1
Dyson, N.J.2
-
62
-
-
0034682037
-
Cell-cycle inhibitors: Three families united by a common cause
-
(doi:10.1016/S0378-1119(00) 00092-5)
-
Vidal A, Koff A. 2000 Cell-cycle inhibitors: three families united by a common cause. Gene 247, 1-15. (doi:10.1016/S0378-1119(00) 00092-5)
-
(2000)
Gene
, vol.247
, pp. 1-15
-
-
Vidal, A.1
Koff, A.2
-
63
-
-
0037052539
-
A complex with chromatin modifiers that occupies E2Fand Myc-responsive genes in G(0) cells
-
(doi:10.1126/science.1069861)
-
Ogawa H, Ishiguro K, Gaubatz S, Livingston DM, Nakatani Y. 2002 A complex with chromatin modifiers that occupies E2Fand Myc-responsive genes in G(0) cells. Science 296, 1132-1136. (doi:10.1126/science.1069861)
-
(2002)
Science
, vol.296
, pp. 1132-1136
-
-
Ogawa, H.1
Ishiguro, K.2
Gaubatz, S.3
Livingston, D.M.4
Nakatani, Y.5
-
64
-
-
0029666482
-
Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts
-
(doi:10.1074/ jbc.271.31.18337)
-
Rivard N, L'Allemain G, Bartek J, Pouyssegur J. 1996 Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts. J. Biol. Chem. 271, 18 337-18 341. (doi:10.1074/ jbc.271.31.18337)
-
(1996)
J. Biol. Chem
, vol.271
, pp. 18337-18341
-
-
Rivard, N.1
L'Allemain, G.2
Bartek, J.3
Pouyssegur, J.4
-
65
-
-
0028990221
-
Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA
-
(doi:10.1073/pnas. 92.10.4352)
-
Nakanishi M, Adami GR, Robetorye RS, Noda A, Venable SF, Dimitrov D, Pereira-Smith OM, Smith JR. 1995 Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA. Proc. Natl Acad. Sci. USA 92, 4352-4356. (doi:10.1073/pnas. 92.10.4352)
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 4352-4356
-
-
Nakanishi, M.1
Adami, G.R.2
Robetorye, R.S.3
Noda, A.4
Venable, S.F.5
Dimitrov, D.6
Pereira-Smith, O.M.7
Smith, J.R.8
-
66
-
-
15444377643
-
p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
-
(doi:10.1101/gad.1272305)
-
Kippin TE, Martens DJ, van der Kooy D. 2005 p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev. 19, 756-767. (doi:10.1101/gad.1272305)
-
(2005)
Genes Dev
, vol.19
, pp. 756-767
-
-
Kippin, T.E.1
Martens, D.J.2
van der Kooy, D.3
-
67
-
-
0033635597
-
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
-
(doi:10. 1101/gad.847700)
-
Dannenberg JH, van Rossum A, Schuijff L, te Riele H. 2000 Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev. 14, 3051-3064. (doi:10. 1101/gad.847700)
-
(2000)
Genes Dev
, vol.14
, pp. 3051-3064
-
-
Dannenberg, J.H.1
van Rossum, A.2
Schuijff, L.3
te Riele, H.4
-
68
-
-
52949114971
-
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
-
(doi:10.1016/j.stem. 2008.07.009)
-
Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, Butte AJ, Passegué E, Sage J. 2008 Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell 3, 416-428. (doi:10.1016/j.stem. 2008.07.009)
-
(2008)
Cell Stem Cell
, vol.3
, pp. 416-428
-
-
Viatour, P.1
Somervaille, T.C.2
Venkatasubrahmanyam, S.3
Kogan, S.4
McLaughlin, M.E.5
Weissman, I.L.6
Butte, A.J.7
Passegué, E.8
Sage, J.9
-
69
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
(doi:10.1101/gad.843200)
-
Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T. 2000 Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev. 14, 3037-3050. (doi:10.1101/gad.843200)
-
(2000)
Genes Dev
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
70
-
-
0038342441
-
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
-
(doi:10.1038/nature01764)
-
Sage J, Miller AL, Perez-Mancera PA, Wysocki JM, Jacks T. 2003 Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424, 223-228. (doi:10.1038/nature01764)
-
(2003)
Nature
, vol.424
, pp. 223-228
-
-
Sage, J.1
Miller, A.L.2
Perez-Mancera, P.A.3
Wysocki, J.M.4
Jacks, T.5
-
71
-
-
0345359924
-
A positive-feedback-based bistable 'memory module' that governs a cell fate decision
-
(doi:10.1038/ nature02089)
-
Xiong W, Ferrell Jr JE. 2003 A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426, 460-465. (doi:10.1038/ nature02089)
-
(2003)
Nature
, vol.426
, pp. 460-465
-
-
Xiong, W.1
Ferrell, J.E.2
-
72
-
-
0037417803
-
Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts
-
(doi:10.1073/pnas. 0235349100)
-
Sha W, Moore J, Chen K, Lassaletta AD, Yi C-S, Tyson JJ, Sible JC. 2003 Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proc. Natl Acad. Sci. USA 100, 975-980. (doi:10.1073/pnas. 0235349100)
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 975-980
-
-
Sha, W.1
Moore, J.2
Chen, K.3
Lassaletta, A.D.4
Yi, C.-S.5
Tyson, J.J.6
Sible, J.C.7
-
73
-
-
1442354192
-
Multistability in the lactose utilization network of Escherichia coli
-
(doi:10.1038/nature02298)
-
Ozbudak EM, Thattai M, Lim HN, Shraiman BI, Van Oudenaarden A. 2004 Multistability in the lactose utilization network of Escherichia coli. Nature 427, 737-740. (doi:10.1038/nature02298)
-
(2004)
Nature
, vol.427
, pp. 737-740
-
-
Ozbudak, E.M.1
Thattai, M.2
Lim, H.N.3
Shraiman, B.I.4
van Oudenaarden, A.5
-
74
-
-
33847394655
-
MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast
-
(doi:10.1038/ nature05561)
-
Paliwal S, Iglesias PA, Campbell K, Hilioti Z, Groisman A, Levchenko A. 2007 MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast. Nature 446, 46-51. (doi:10.1038/ nature05561)
-
(2007)
Nature
, vol.446
, pp. 46-51
-
-
Paliwal, S.1
Iglesias, P.A.2
Campbell, K.3
Hilioti, Z.4
Groisman, A.5
Levchenko, A.6
-
75
-
-
0037376655
-
Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell
-
(doi:10.1016/S0955-0674(03)00017-6)
-
Tyson JJ, Chen KC, Novak B. 2003 Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr. Opin. Cell Biol. 15, 221-231. (doi:10.1016/S0955-0674(03)00017-6)
-
(2003)
Curr. Opin. Cell Biol
, vol.15
, pp. 221-231
-
-
Tyson, J.J.1
Chen, K.C.2
Novak, B.3
-
76
-
-
0036532226
-
Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
-
(doi:10.1016/S0955-0674(02)00314-9)
-
Ferrell Jr JE. 2002 Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr. Opin. Cell Biol. 14, 140-148. (doi:10.1016/S0955-0674(02)00314-9)
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 140-148
-
-
Ferrell, J.E.1
-
77
-
-
58049208229
-
Ordered cyclic motifs contribute to dynamic stability in biological and engineered networks
-
(doi:10.1073/pnas.0805344105)
-
Ma'Ayan A, Cecchi GA, Wagner J, Rao AR, Iyengar R, Stolovitzky G. 2008 Ordered cyclic motifs contribute to dynamic stability in biological and engineered networks. Proc. Natl Acad. Sci. USA 105, 19 235-19 240. (doi:10.1073/pnas.0805344105)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.1
, pp. 19235-19240
-
-
Ma'Ayan, A.1
Cecchi, G.A.2
Wagner, J.3
Rao, A.R.4
Iyengar, R.5
Stolovitzky, G.6
-
78
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
(doi:10.1101/ gad.11.11.1464)
-
Sheaff RJ, Groudine M, Gordon M, Roberts JM, Clurman BE. 1997 Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11, 1464-1478. (doi:10.1101/ gad.11.11.1464)
-
(1997)
Genes Dev
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.J.1
Groudine, M.2
Gordon, M.3
Roberts, J.M.4
Clurman, B.E.5
-
79
-
-
0033453231
-
The kinetic origins of the restriction point in the mammalian cell cycle
-
(doi:10.1046/j.1365-2184. 1999.3250321.x)
-
Aguda BD, Tang Y. 1999 The kinetic origins of the restriction point in the mammalian cell cycle. Cell Prolif. 32, 321-335. (doi:10.1046/j.1365-2184. 1999.3250321.x)
-
(1999)
Cell Prolif
, vol.32
, pp. 321-335
-
-
Aguda, B.D.1
Tang, Y.2
-
80
-
-
4444349425
-
A model for restriction point control of the mammalian cell cycle
-
(doi:10.1016/j.jtbi.2004. 04.039)
-
Novak B, Tyson JJ. 2004 A model for restriction point control of the mammalian cell cycle. J. Theor. Biol. 230, 563-579. (doi:10.1016/j.jtbi.2004. 04.039)
-
(2004)
J. Theor. Biol
, vol.230
, pp. 563-579
-
-
Novak, B.1
Tyson, J.J.2
-
81
-
-
0033590255
-
A mathematical description of regulation of the G1-S transition of the mammalian cell cycle
-
(doi:10.1002/(SICI)1097-0290(19991220)65:6,631::AID-BIT3.3.0.CO;2-7)
-
Hatzimanikatis V, Lee KH, Bailey JE. 1999 A mathematical description of regulation of the G1-S transition of the mammalian cell cycle. Biotechnol. Bioeng. 65, 631-637. (doi:10.1002/(SICI)1097-0290(19991220)65:6,631::AID-BIT3.3.0.CO;2-7)
-
(1999)
Biotechnol. Bioeng
, vol.65
, pp. 631-637
-
-
Hatzimanikatis, V.1
Lee, K.H.2
Bailey, J.E.3
-
82
-
-
0344982141
-
Dynamics of the cell cycle: Checkpoints, sizers, and timers
-
(doi:10.1016/S0006-3495(03)74778-X)
-
Qu Z, MacLellan WR, Weiss JN. 2003 Dynamics of the cell cycle: checkpoints, sizers, and timers. Biophys. J. 85, 3600-3611. (doi:10.1016/S0006-3495(03)74778-X)
-
(2003)
Biophys. J
, vol.85
, pp. 3600-3611
-
-
Qu, Z.1
Maclellan, W.R.2
Weiss, J.N.3
-
83
-
-
0030767422
-
Bistable biochemical switching and the control of the events of the cell cycle
-
(doi:10.1038/sj.onc.1201190)
-
Thron CD. 1997 Bistable biochemical switching and the control of the events of the cell cycle. Oncogene 15, 317-325. (doi:10.1038/sj.onc.1201190)
-
(1997)
Oncogene
, vol.15
, pp. 317-325
-
-
Thron, C.D.1
-
84
-
-
43149108161
-
A bistable Rb-E2F switch underlies the restriction point
-
(doi:10.1038/ ncb1711)
-
Yao G, Lee TJ, Mori S, Nevins JR, You L. 2008 A bistable Rb-E2F switch underlies the restriction point. Nat. Cell Biol. 10, 476-482. (doi:10.1038/ ncb1711)
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 476-482
-
-
Yao, G.1
Lee, T.J.2
Mori, S.3
Nevins, J.R.4
You, L.5
-
85
-
-
79955553550
-
Origin of bistability underlying mammalian cell cycle entry
-
(doi:10.1038/msb. 2011.19)
-
Yao G, Tan C, West M, Nevins JR, You L. 2011 Origin of bistability underlying mammalian cell cycle entry. Mol. Syst. Biol. 7, 485. (doi:10.1038/msb. 2011.19)
-
(2011)
Mol. Syst. Biol
, vol.7
, pp. 485
-
-
Yao, G.1
Tan, C.2
West, M.3
Nevins, J.R.4
You, L.5
-
86
-
-
77957894780
-
Stochastic E2F activation and reconciliation of phenomenological cell-cycle models
-
(doi:10.1371/journal.pbio.1000488)
-
Lee T, Yao G, Bennett DC, Nevins JR, You L. 2010 Stochastic E2F activation and reconciliation of phenomenological cell-cycle models. PLoS Biol. 8, e1000488. (doi:10.1371/journal.pbio.1000488)
-
(2010)
PLoS Biol
, vol.8
-
-
Lee, T.1
Yao, G.2
Bennett, D.C.3
Nevins, J.R.4
You, L.5
-
87
-
-
0026099022
-
The MYC protein activates transcription of the alpha-prothymosin gene
-
Eilers M, Schirm S, Bishop JM. 1991 The MYC protein activates transcription of the alpha-prothymosin gene. EMBO J. 10, 133-141.
-
(1991)
EMBO J
, vol.10
, pp. 133-141
-
-
Eilers, M.1
Schirm, S.2
Bishop, J.M.3
-
88
-
-
38549161152
-
Cell fate determination during G1 phase progression
-
(doi:10.1007/s00018-007-7271-z)
-
Blomen VA, Boonstra J. 2007 Cell fate determination during G1 phase progression. Cell Mol. Life Sci. 64, 3084-3104. (doi:10.1007/s00018-007-7271-z)
-
(2007)
Cell Mol. Life Sci
, vol.64
, pp. 3084-3104
-
-
Blomen, V.A.1
Boonstra, J.2
-
89
-
-
0030477686
-
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
-
(doi:10.1073/pnas.93.24.13742)
-
Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, Barrett JC. 1996 Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc. Natl Acad. Sci. USA 93, 13 742-13 747. (doi:10.1073/pnas.93.24.13742)
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 13742-13747
-
-
Alcorta, D.A.1
Xiong, Y.2
Phelps, D.3
Hannon, G.4
Beach, D.5
Barrett, J.C.6
-
90
-
-
0033013980
-
Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts
-
Stein GH, Drullinger LF, Soulard A, Dulic V. 1999 Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts. Mol. Cell Biol. 19, 2109-2117.
-
(1999)
Mol. Cell Biol
, vol.19
, pp. 2109-2117
-
-
Stein, G.H.1
Drullinger, L.F.2
Soulard, A.3
Dulic, V.4
-
91
-
-
14644422293
-
Increased stability of the p16 mRNA with replicative senescence
-
(doi:10.1038/sj.embor.7400346)
-
Wang W, Martindale JL, Yang X, Chrest FJ, Gorospe M. 2005 Increased stability of the p16 mRNA with replicative senescence. EMBO Rep. 6, 158-164. (doi:10.1038/sj.embor.7400346)
-
(2005)
EMBO Rep
, vol.6
, pp. 158-164
-
-
Wang, W.1
Martindale, J.L.2
Yang, X.3
Chrest, F.J.4
Gorospe, M.5
-
92
-
-
36749101915
-
Non-proliferation as an active state- conceptual and practical implications
-
(doi:10.4161/cc.6.12.4378)
-
Pajalunga D, Mazzola A, Puggioni E, Crescenzi M. 2007 Non-proliferation as an active state- conceptual and practical implications. Cell Cycle 6, 1415-1418. (doi:10.4161/cc.6.12.4378)
-
(2007)
Cell Cycle
, vol.6
, pp. 1415-1418
-
-
Pajalunga, D.1
Mazzola, A.2
Puggioni, E.3
Crescenzi, M.4
-
93
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
(doi:10.1093/ emboj/cdg417)
-
Beausejour CM, Krtolica A, Galimi F, Narita M, Lowe SW, Yaswen P, Campisi J. 2003 Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J. 22, 4212-4222. (doi:10.1093/ emboj/cdg417)
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
94
-
-
0034934780
-
Reconstitution of cyclin D1-associated kinase activity drives terminally differentiated cells into the cell cycle
-
(doi:10.1128/ MCB.21.16.5631-5643.2001)
-
Latella L, Sacco A, Pajalunga D, Tiainen M, Macera D, D'Angelo M, Felici A, Sacchi A, Crescenzi M. 2001 Reconstitution of cyclin D1-associated kinase activity drives terminally differentiated cells into the cell cycle. Mol. Cell Biol. 21, 5631-5643. (doi:10.1128/ MCB.21.16.5631-5643.2001)
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 5631-5643
-
-
Latella, L.1
Sacco, A.2
Pajalunga, D.3
Tiainen, M.4
Macera, D.5
D'Angelo, M.6
Felici, A.7
Sacchi, A.8
Crescenzi, M.9
-
95
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
(doi:10.1126/science.284.5415.770)
-
Artavanis-Tsakonas S, Rand MD, Lake RJ. 1999 Notch signaling: cell fate control and signal integration in development. Science 284, 770-776. (doi:10.1126/science.284.5415.770)
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
96
-
-
84862942273
-
Notch signaling is necessary to maintain quiescence in adult muscle stem cells
-
(doi:10.1002/ stem.773)
-
Bjornson CRR, Cheung TH, Liu L, Tripathi PV, Steeper KM, Rando TA. 2012 Notch signaling is necessary to maintain quiescence in adult muscle stem cells. Stem Cells 30, 232-242. (doi:10.1002/ stem.773)
-
(2012)
Stem Cells
, vol.30
, pp. 232-242
-
-
Bjornson, C.R.R.1
Cheung, T.H.2
Liu, L.3
Tripathi, P.V.4
Steeper, K.M.5
Rando, T.A.6
-
97
-
-
84856118451
-
A critical requirement for notch signaling in maintenance of the quiescent skeletal muscle stem cell state
-
(doi:10.1002/stem.775)
-
Mourikis P, Sambasivan R, Castel D, Rocheteau P, Bizzarro V, Tajbakhsh S. 2012 A critical requirement for notch signaling in maintenance of the quiescent skeletal muscle stem cell state. Stem Cells 30, 243-252. (doi:10.1002/stem.775)
-
(2012)
Stem Cells
, vol.30
, pp. 243-252
-
-
Mourikis, P.1
Sambasivan, R.2
Castel, D.3
Rocheteau, P.4
Bizzarro, V.5
Tajbakhsh, S.6
-
98
-
-
68049112459
-
Fear of commitment: Hes1 protects quiescent fibroblasts from irreversible cellular fates
-
(doi:10. 4161/cc.8.14.9104)
-
Sang L, Coller HA. 2009 Fear of commitment: Hes1 protects quiescent fibroblasts from irreversible cellular fates. Cell Cycle 8, 2161-2167. (doi:10. 4161/cc.8.14.9104)
-
(2009)
Cell Cycle
, vol.8
, pp. 2161-2167
-
-
Sang, L.1
Coller, H.A.2
-
99
-
-
10044271901
-
HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1
-
(doi:10.1038/sj.onc.1208139)
-
Hartman J, Müller P, Foster JS, Wimalasena J, Gustafsson J, Ström A. 2004 HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1. Oncogene 23, 8826-8833. (doi:10.1038/sj.onc.1208139)
-
(2004)
Oncogene
, vol.23
, pp. 8826-8833
-
-
Hartman, J.1
Müller, P.2
Foster, J.S.3
Wimalasena, J.4
Gustafsson, J.5
Ström, A.6
-
100
-
-
0037088627
-
Blocking HES1 expression initiates GABAergic differentiation and induces the expression of p21(CIP1/WAF1) in human neural stem cells
-
(doi:10.1074/jbc.C100758200)
-
Kabos P, Kabosova A, Neuman T. 2002 Blocking HES1 expression initiates GABAergic differentiation and induces the expression of p21(CIP1/WAF1) in human neural stem cells. J. Biol. Chem. 277, 8763-8766. (doi:10.1074/jbc.C100758200)
-
(2002)
J. Biol. Chem
, vol.277
, pp. 8763-8766
-
-
Kabos, P.1
Kabosova, A.2
Neuman, T.3
-
101
-
-
18144386919
-
Hes1 directly controls cell proliferation through the transcriptional repression of p27(Kip1)
-
(doi:10.1128/MCB.25.10.4262-4271.2005)
-
Murata K, Hattori M, Hirai N, Shinozuka Y, Hirata H, Kageyama R, Sakai T, Minato N. 2005 Hes1 directly controls cell proliferation through the transcriptional repression of p27(Kip1). Mol. Cell. Biol. 25, 4262-4271. (doi:10.1128/MCB.25.10.4262-4271.2005)
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 4262-4271
-
-
Murata, K.1
Hattori, M.2
Hirai, N.3
Shinozuka, Y.4
Hirata, H.5
Kageyama, R.6
Sakai, T.7
Minato, N.8
-
102
-
-
0037124024
-
A role for p53 in maintaining and establishing the quiescence growth arrest in human cells
-
(doi:10.1074/jbc.M201028200)
-
Itahana K et al. 2002 A role for p53 in maintaining and establishing the quiescence growth arrest in human cells. J. Biol. Chem. 277, 18 206-18 214. (doi:10.1074/jbc.M201028200)
-
(2002)
J. Biol. Chem
, vol.277
, pp. 18206-18214
-
-
Itahana, K.1
-
103
-
-
58049216794
-
p53 regulates hematopoietic stem cell quiescence
-
(doi:10. 1016/j.stem.2008.11.006)
-
Liu Y et al. 2009 p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 4, 37-48. (doi:10. 1016/j.stem.2008.11.006)
-
(2009)
Cell Stem Cell
, vol.4
, pp. 37-48
-
-
Liu, Y.1
-
104
-
-
7244231429
-
Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
-
(doi:10.1038/nature02994)
-
Hock H, Hamblen MJ, Rooke HM, Schindler JW, Saleque S, Fujiwara Y, Orkin SH. 2004 Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature 431, 1002-1007. (doi:10.1038/nature02994)
-
(2004)
Nature
, vol.431
, pp. 1002-1007
-
-
Hock, H.1
Hamblen, M.J.2
Rooke, H.M.3
Schindler, J.W.4
Saleque, S.5
Fujiwara, Y.6
Orkin, S.H.7
-
105
-
-
33644819269
-
The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells
-
(doi:10.1016/j.ccr.2006.02.017)
-
Lacorazza HD, Yamada T, Liu Y, Miyata Y, Sivina M, Nunes J, Nimer SD. 2006 The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells. Cancer Cell 9, 175-187. (doi:10.1016/j.ccr.2006.02.017)
-
(2006)
Cancer Cell
, vol.9
, pp. 175-187
-
-
Lacorazza, H.D.1
Yamada, T.2
Liu, Y.3
Miyata, Y.4
Sivina, M.5
Nunes, J.6
Nimer, S.D.7
-
106
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
(doi:10.1038/ nature01036)
-
Kops GJ et al. 2002 Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419, 316-321. (doi:10.1038/ nature01036)
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
-
107
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
(doi:10.1016/j. cell.2007.01.003)
-
Tothova Z et al. 2007 FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128, 325-339. (doi:10.1016/j. cell.2007.01.003)
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
-
108
-
-
84860528235
-
The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells
-
(doi:10.1038/ncb2468)
-
Maryanovich M, Oberkovitz G, Niv H, Vorobiyov L, Zaltsman Y, Brenner O, Lapidot T, Jung S, Gross A. 2012 The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells. Nat. Cell Biol. 14, 535-541. (doi:10.1038/ncb2468)
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 535-541
-
-
Maryanovich, M.1
Oberkovitz, G.2
Niv, H.3
Vorobiyov, L.4
Zaltsman, Y.5
Brenner, O.6
Lapidot, T.7
Jung, S.8
Gross, A.9
-
109
-
-
0034941567
-
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells
-
(doi:10.1128/MCB.21.16.5644-5657. 2001)
-
Rossig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM, Dimmeler S. 2001 Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol. Cell Biol. 21, 5644-5657. (doi:10.1128/MCB.21.16.5644-5657. 2001)
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
110
-
-
0034745353
-
Cytoplasmic localization of p21Cip1/ WAF1 by Akt-induced phosphorylation in HER-2/ neu-overexpressing cells
-
(doi:10.1038/35060032)
-
Zhou BP, Liao Y, Xia W, Spohn B, Lee M-H, Hung M-C. 2001 Cytoplasmic localization of p21Cip1/ WAF1 by Akt-induced phosphorylation in HER-2/ neu-overexpressing cells. Nat. Cell Biol. 3, 245-252. (doi:10.1038/35060032)
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 245-252
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Spohn, B.4
Lee, M.-H.5
Hung, M.-C.6
-
111
-
-
77956217067
-
Regulation of the HIF-1 alpha level is essential for hematopoietic stem cells
-
(doi:10.1016/j.stem.2010.06. 020)
-
Takubo K et al. 2010 Regulation of the HIF-1 alpha level is essential for hematopoietic stem cells. Cell Stem Cell 7, 391-402. (doi:10.1016/j.stem.2010.06. 020)
-
(2010)
Cell Stem Cell
, vol.7
, pp. 391-402
-
-
Takubo, K.1
-
112
-
-
78649851511
-
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
-
(doi:10.1038/nature09572)
-
Gurumurthy S et al. 2010 The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468, 659-663. (doi:10.1038/nature09572)
-
(2010)
Nature
, vol.468
, pp. 659-663
-
-
Gurumurthy, S.1
-
113
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
(doi:10.1038/ nature09595)
-
Gan B et al. 2010 Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468, 701-704. (doi:10.1038/ nature09595)
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
-
114
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
(doi:10.1038/nature09571)
-
Nakada D, Saunders TL, Morrison SJ. 2010 Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468, 653-658. (doi:10.1038/nature09571)
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
115
-
-
45149123052
-
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
-
(doi:10.1084/jem.20080277)
-
Thompson BJ, Jankovic V, Gao J, Buonamici S, Vest A, Lee JM, Zavadil J, Nimer SD, Aifantis I. 2008 Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7. J. Exp. Med. 205, 1395-1408. (doi:10.1084/jem.20080277)
-
(2008)
J. Exp. Med
, vol.205
, pp. 1395-1408
-
-
Thompson, B.J.1
Jankovic, V.2
Gao, J.3
Buonamici, S.4
Vest, A.5
Lee, J.M.6
Zavadil, J.7
Nimer, S.D.8
Aifantis, I.9
-
116
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
(doi:10.1038/nature04703)
-
Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu H, Morrison SJ. 2006 Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441, 475-482. (doi:10.1038/nature04703)
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
117
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
(doi:10.1038/ nature04747)
-
Zhang J et al. 2006 PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441, 518-522. (doi:10.1038/ nature04747)
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
-
118
-
-
44349166602
-
PML targeting eradicates quiescent leukaemia-initiating cells
-
(doi:10.1038/nature07016)
-
Ito K et al. 2008 PML targeting eradicates quiescent leukaemia-initiating cells. Nature 453, 1072-1078. (doi:10.1038/nature07016)
-
(2008)
Nature
, vol.453
, pp. 1072-1078
-
-
Ito, K.1
-
119
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
(doi:10. 1084/jem.20081297)
-
Chen C, Liu Y, Liu R, Ikenoue T, Guan K-L, Liu Y, Zheng P. 2008 TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Med. 205, 2397-2408. (doi:10. 1084/jem.20081297)
-
(2008)
J. Exp. Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.-L.5
Liu, Y.6
Zheng, P.7
-
120
-
-
80052507407
-
E2F transcription factor-1 regulates oxidative metabolism
-
(doi:10.1038/ncb2309)
-
Blanchet E et al. 2011 E2F transcription factor-1 regulates oxidative metabolism. Nat. Cell Biol. 13, 1146-1152. (doi:10.1038/ncb2309)
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 1146-1152
-
-
Blanchet, E.1
-
121
-
-
50849129599
-
Autophagy is activated, but is not required for the G(0) function of BCL-2 or BCL-x(L)
-
(doi:10.4161/cc. 7.17.6595)
-
Valentin M, Yang E. 2008 Autophagy is activated, but is not required for the G(0) function of BCL-2 or BCL-x(L). Cell Cycle 7, 2762-2768. (doi:10.4161/cc. 7.17.6595)
-
(2008)
Cell Cycle
, vol.7
, pp. 2762-2768
-
-
Valentin, M.1
Yang, E.2
-
122
-
-
0028222874
-
Autophagy and related mechanisms of lysosome-mediated protein degradation
-
(doi:10. 1016/0962-8924(94)90069-8)
-
Dunn Jr WA. 1994 Autophagy and related mechanisms of lysosome-mediated protein degradation. Trends Cell Biol. 4, 139-143. (doi:10. 1016/0962-8924(94)90069-8)
-
(1994)
Trends Cell Biol
, vol.4
, pp. 139-143
-
-
Dunn, W.A.1
-
123
-
-
0034537290
-
Cell biology-autophagy as a regulated pathway of cellular degradation
-
(doi:10.1126/science.290. 5497.1717)
-
Klionsky DJ, Emr SD. 2000 Cell biology-autophagy as a regulated pathway of cellular degradation. Science 290, 1717-1721. (doi:10.1126/science.290. 5497.1717)
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
124
-
-
78649704325
-
Autophagy and metabolism
-
(doi:10. 1126/science.1193497)
-
Rabinowitz JD, White E. 2010 Autophagy and metabolism. Science 330, 1344-1348. (doi:10. 1126/science.1193497)
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
125
-
-
79952728102
-
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
-
(doi:10. 1084/jem.20101145)
-
Mortensen M et al. 2011 The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J. Exp. Med. 208, 455-467. (doi:10. 1084/jem.20101145)
-
(2011)
J. Exp. Med
, vol.208
, pp. 455-467
-
-
Mortensen, M.1
-
126
-
-
65249155441
-
An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation
-
(doi:10. 1091/mbc.E08-12-1250)
-
Chang YY, Neufeld TP. 2009 An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation. Mol. Biol. Cell 20, 2004-2014. (doi:10. 1091/mbc.E08-12-1250)
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2004-2014
-
-
Chang, Y.Y.1
Neufeld, T.P.2
-
127
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
(doi:10.1091/mbc.E08-12-1249)
-
Jung CH, Jun CB, Ro S-H, Kim Y-M, Otto NM, Cao J, Kundu M, Kim D-H. 2009 ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol. Biol. Cell 20, 1992-2003. (doi:10.1091/mbc.E08-12-1249)
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.-H.3
Kim, Y.-M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.-H.8
-
128
-
-
75749090429
-
Tor directly controls the Atg1 kinase complex to regulate autophagy
-
(doi:10. 1128/MCB.01344-09)
-
Kamada Y, Yoshino K-I, Kondo C, Kawamata T, Oshiro N, Yonezawa K, Ohsumi Y. 2010 Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol. Cell. Biol. 30, 1049-1058. (doi:10. 1128/MCB.01344-09)
-
(2010)
Mol. Cell. Biol
, vol.30
, pp. 1049-1058
-
-
Kamada, Y.1
Yoshino, K.-I.2
Kondo, C.3
Kawamata, T.4
Oshiro, N.5
Yonezawa, K.6
Ohsumi, Y.7
-
129
-
-
78049262912
-
The RB-E2F1 pathway regulates autophagy
-
(doi:10. 1158/0008-5472.CAN-10-1604)
-
Jiang H et al. 2010 The RB-E2F1 pathway regulates autophagy. Cancer Res 70, 7882-7893. (doi:10. 1158/0008-5472.CAN-10-1604)
-
(2010)
Cancer Res
, vol.70
, pp. 7882-7893
-
-
Jiang, H.1
-
130
-
-
49649121765
-
E2F1 regulates autophagy and the transcription of autophagy genes
-
(doi:10.1038/onc. 2008.117)
-
Polager S, Ofir M, Ginsberg D. 2008 E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 27, 4860-4864. (doi:10.1038/onc. 2008.117)
-
(2008)
Oncogene
, vol.27
, pp. 4860-4864
-
-
Polager, S.1
Ofir, M.2
Ginsberg, D.3
-
131
-
-
84863115641
-
Maintenance of muscle stem-cell quiescence by microRNA-489
-
(doi:10. 1038/nature10834)
-
Cheung TH, Quach NL, Charville GW, Liu L, Park L, Edalati A, Yoo B, Hoang P, Rando TA. 2012 Maintenance of muscle stem-cell quiescence by microRNA-489. Nature 482, 524-528. (doi:10. 1038/nature10834)
-
(2012)
Nature
, vol.482
, pp. 524-528
-
-
Cheung, T.H.1
Quach, N.L.2
Charville, G.W.3
Liu, L.4
Park, L.5
Edalati, A.6
Yoo, B.7
Hoang, P.8
Rando, T.A.9
-
132
-
-
79955570371
-
MicroRNA programs in normal and aberrant stem and progenitor cells
-
(doi:10.1101/gr.111385.110)
-
Arnold CP et al. 2011 MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res. 21, 798-810. (doi:10.1101/gr.111385.110)
-
(2011)
Genome Res
, vol.21
, pp. 798-810
-
-
Arnold, C.P.1
-
133
-
-
79952126479
-
Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment
-
(doi:10. 1016/j.stem.2011.01.014)
-
Zhang L, Stokes N, Polak L, Fuchs E. 2011 Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell 8, 294-308. (doi:10. 1016/j.stem.2011.01.014)
-
(2011)
Cell Stem Cell
, vol.8
, pp. 294-308
-
-
Zhang, L.1
Stokes, N.2
Polak, L.3
Fuchs, E.4
-
134
-
-
84871358614
-
A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts
-
(doi:10.1186/gb-2012-13-12-r121)
-
Suh EJ et al. 2012 A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts. Genome Biol. 13, R121. (doi:10.1186/gb-2012-13-12-r121)
-
(2012)
Genome Biol
, vol.13
-
-
Suh, E.J.1
-
135
-
-
84870894496
-
Attenuation of miR-126 activity expands hsc in vivo without exhaustion
-
(doi:10.1016/j.stem.2012.09.001)
-
Lechman ER et al. 2012 Attenuation of miR-126 activity expands hsc in vivo without exhaustion. Cell Stem Cell 11, 799-811. (doi:10.1016/j.stem.2012.09.001)
-
(2012)
Cell Stem Cell
, vol.11
, pp. 799-811
-
-
Lechman, E.R.1
-
136
-
-
84863230221
-
Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
-
(doi:10.1016/ j.stem.2012.01.017)
-
Boutet SC et al. 2012 Alternative polyadenylation mediates microRNA regulation of muscle stem cell function. Cell Stem Cell 10, 327-336. (doi:10.1016/ j.stem.2012.01.017)
-
(2012)
Cell Stem Cell
, vol.10
, pp. 327-336
-
-
Boutet, S.C.1
-
137
-
-
46249092601
-
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
-
(doi:10.1126/science.1155390)
-
Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. 2008 Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 320, 1643-1647. (doi:10.1126/science.1155390)
-
(2008)
Science
, vol.320
, pp. 1643-1647
-
-
Sandberg, R.1
Neilson, J.R.2
Sarma, A.3
Sharp, P.A.4
Burge, C.B.5
-
138
-
-
68749113985
-
Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
-
(doi:10.1016/j.cell.2009.06.016)
-
Mayr C, Bartel DP. 2009 Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138, 673-684. (doi:10.1016/j.cell.2009.06.016)
-
(2009)
Cell
, vol.138
, pp. 673-684
-
-
Mayr, C.1
Bartel, D.P.2
-
139
-
-
42349093068
-
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival
-
(doi:10.1158/0008-5472.CAN-07-6754)
-
Medina R, Zaidi SK, Liu C-G, Stein JL, vanWijnen AJ, Croce CM, Stein GS. 2008 MicroRNAs 221 and 222 bypass quiescence and compromise cell survival. Cancer Res. 68, 2773-2780. (doi:10.1158/0008-5472.CAN-07-6754)
-
(2008)
Cancer Res
, vol.68
, pp. 2773-2780
-
-
Medina, R.1
Zaidi, S.K.2
Liu, C.-G.3
Stein, J.L.4
Vanwijnen, A.J.5
Croce, C.M.6
Stein, G.S.7
-
140
-
-
34548268220
-
Regulation of p27Kip1 by miRNA 221/222 in glioblastoma
-
(doi:10.4161/cc.6. 16.4526)
-
Gillies JK, Lorimer IA. 2007 Regulation of p27Kip1 by miRNA 221/222 in glioblastoma. Cell Cycle 6, 2005-2009. (doi:10.4161/cc.6. 16.4526)
-
(2007)
Cell Cycle
, vol.6
, pp. 2005-2009
-
-
Gillies, J.K.1
Lorimer, I.A.2
-
141
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
(doi:10.1158/ 0008-5472.CAN-07-2462)
-
Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ. 2007 MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res. 67, 9762-9770. (doi:10.1158/ 0008-5472.CAN-07-2462)
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
Yang, Q.4
Aris, V.5
Soteropoulos, P.6
Petrelli, N.J.7
Dunn, S.P.8
Krueger, L.J.9
-
142
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
(doi:10.1038/nature03677)
-
O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. 2005 c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435, 839-843. (doi:10.1038/nature03677)
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
143
-
-
34047267329
-
An E2F/miR-20a autoregulatory feedback loop
-
(doi:10.1074/jbc. M608939200)
-
Sylvestre Y, De Guire V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F, Ferbeyre G, Chartrand P. 2007 An E2F/miR-20a autoregulatory feedback loop. J. Biol. Chem. 282, 2135-2143. (doi:10.1074/jbc. M608939200)
-
(2007)
J. Biol. Chem
, vol.282
, pp. 2135-2143
-
-
Sylvestre, Y.1
de Guire, V.2
Querido, E.3
Mukhopadhyay, U.K.4
Bourdeau, V.5
Major, F.6
Ferbeyre, G.7
Chartrand, P.8
-
144
-
-
80054711591
-
MicroRNA-mediated positive feedback loop and optimized bistable switch in a cancer network involving miR-17-92
-
(doi:10.1371/journal.pone. 0026302)
-
Li Y, Zhang H, Chen Y. 2011 MicroRNA-mediated positive feedback loop and optimized bistable switch in a cancer network involving miR-17-92. PLoS ONE 6, e26302. (doi:10.1371/journal.pone. 0026302)
-
(2011)
PLoS ONE
, vol.6
-
-
Li, Y.1
Zhang, H.2
Chen, Y.3
-
145
-
-
58149382580
-
MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc
-
(doi:10.1073/ pnas.0811166106)
-
Aguda BD, Kim Y, Piper-Hunter MG, Friedman A, Marsh CB. 2008 MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc. Proc. Natl Acad. Sci. USA 105, 19 678-19 683. (doi:10.1073/ pnas.0811166106)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19678-19683
-
-
Aguda, B.D.1
Kim, Y.2
Piper-Hunter, M.G.3
Friedman, A.4
Marsh, C.B.5
-
146
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
(doi:10.1101/gad.947102)
-
Bird A. 2002 DNA methylation patterns and epigenetic memory. Genes Dev. 16, 6-21. (doi:10.1101/gad.947102)
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
147
-
-
33847032960
-
The mammalian epigenome
-
(doi:10.1016/j.cell.2007.01.033)
-
Bernstein BE, Meissner A, Lander ES. 2007 The mammalian epigenome. Cell 128, 669-681. (doi:10.1016/j.cell.2007.01.033)
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
148
-
-
33845877732
-
Defining an epigenetic code
-
(doi:10.1038/ncb0107-2)
-
Turner BM. 2007 Defining an epigenetic code. Nat. Cell Biol. 9, 2-6. (doi:10.1038/ncb0107-2)
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 2-6
-
-
Turner, B.M.1
-
149
-
-
77953527600
-
Regulation of cellular chromatin state: Insights from quiescence and differentiation
-
(doi:10.4161/org.6.1.11337)
-
Srivastava S, Mishra RK, Dhawan J. 2010 Regulation of cellular chromatin state: insights from quiescence and differentiation. Organogenesis 6, 37-47. (doi:10.4161/org.6.1.11337)
-
(2010)
Organogenesis
, vol.6
, pp. 37-47
-
-
Srivastava, S.1
Mishra, R.K.2
Dhawan, J.3
-
150
-
-
33344469959
-
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
(doi:10.1182/ blood-2005-09-3585)
-
Kamminga LM et al. 2006 The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107, 2170-2179. (doi:10.1182/ blood-2005-09-3585)
-
(2006)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
-
151
-
-
84868340057
-
Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest
-
(doi:10.1016/j.stem.2012.08.001)
-
Hidalgo I, Herrera-Merchan A, Ligos JM, Carramolino L, Nuñez J, Martinez F, Dominguez O, Torres M, Gonzalez S. 2012 Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest. Cell Stem Cell 11, 649-662. (doi:10.1016/j.stem.2012.08.001)
-
(2012)
Cell Stem Cell
, vol.11
, pp. 649-662
-
-
Hidalgo, I.1
Herrera-Merchan, A.2
Ligos, J.M.3
Carramolino, L.4
Nuñez, J.5
Martinez, F.6
Dominguez, O.7
Torres, M.8
Gonzalez, S.9
-
152
-
-
79952220410
-
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
-
(doi:10.1101/gad.2019811)
-
Ezhkova E, Lien W-H, Stokes N, Pasolli HA, Silva JM, Fuchs E. 2011 EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev. 25, 485-498. (doi:10.1101/gad.2019811)
-
(2011)
Genes Dev
, vol.25
, pp. 485-498
-
-
Ezhkova, E.1
Lien, W.-H.2
Stokes, N.3
Pasolli, H.A.4
Silva, J.M.5
Fuchs, E.6
-
153
-
-
84884795416
-
H4K20 methylation regulates quiescence and chromatin compaction
-
(doi:10.1091/mbc.E12-07-0529)
-
Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA. 2013 H4K20 methylation regulates quiescence and chromatin compaction. Mol. Biol. Cell 24, 3025-3037. (doi:10.1091/mbc.E12-07-0529)
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 3025-3037
-
-
Evertts, A.G.1
Manning, A.L.2
Wang, X.3
Dyson, N.J.4
Garcia, B.A.5
Coller, H.A.6
-
154
-
-
36749080303
-
E2F-associated chromatin modifiers and cell cycle control
-
(doi:10.1016/j.ceb.2007.10.003)
-
Blais A, Dynlacht BD. 2007 E2F-associated chromatin modifiers and cell cycle control. Curr. Opin. Cell Biol. 19, 658-662. (doi:10.1016/j.ceb.2007.10.003)
-
(2007)
Curr. Opin. Cell Biol
, vol.19
, pp. 658-662
-
-
Blais, A.1
Dynlacht, B.D.2
-
155
-
-
33748269854
-
Proteolysis of MLL family proteins is essential for Taspase1-orchestrated cell cycle progression
-
(doi:10.1101/gad.1449406)
-
Takeda S et al. 2006 Proteolysis of MLL family proteins is essential for Taspase1-orchestrated cell cycle progression. Genes Dev. 20, 2397-2409. (doi:10.1101/gad.1449406)
-
(2006)
Genes Dev
, vol.20
, pp. 2397-2409
-
-
Takeda, S.1
-
156
-
-
34250823511
-
E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases
-
(doi:10. 1016/j.molcel.2007.05.030)
-
Tyagi S, Chabes AL, Wysocka J, Herr W. 2007 E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases. Mol. Cell 27, 107-119. (doi:10. 1016/j.molcel.2007.05.030)
-
(2007)
Mol. Cell
, vol.27
, pp. 107-119
-
-
Tyagi, S.1
Chabes, A.L.2
Wysocka, J.3
Herr, W.4
|