메뉴 건너뛰기




Volumn 3, Issue 4, 2008, Pages 416-428

Hematopoietic Stem Cell Quiescence Is Maintained by Compound Contributions of the Retinoblastoma Gene Family

Author keywords

CELLCYCLE; HUMDISEASE; STEMCELL

Indexed keywords

PROTEIN P107; PROTEIN P130; RETINOBLASTOMA PROTEIN;

EID: 52949114971     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2008.07.009     Document Type: Article
Times cited : (131)

References (44)
  • 2
    • 0000099705 scopus 로고
    • Generation of normal lymphocyte populations by Rb-deficient embryonic stem cells
    • Chen J., Gorman J.R., Stewart V., Williams B., Jacks T., and Alt F.W. Generation of normal lymphocyte populations by Rb-deficient embryonic stem cells. Curr. Biol. 3 (1993) 405-413
    • (1993) Curr. Biol. , vol.3 , pp. 405-413
    • Chen, J.1    Gorman, J.R.2    Stewart, V.3    Williams, B.4    Jacks, T.5    Alt, F.W.6
  • 3
    • 0033694302 scopus 로고    scopus 로고
    • Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
    • Cheng T., Rodrigues N., Dombkowski D., Stier S., and Scadden D.T. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat. Med. 6 (2000) 1235-1240
    • (2000) Nat. Med. , vol.6 , pp. 1235-1240
    • Cheng, T.1    Rodrigues, N.2    Dombkowski, D.3    Stier, S.4    Scadden, D.T.5
  • 6
    • 41349095902 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress
    • Daria D., Filippi M.D., Knudsen E.S., Faccio R., Li Z., Kalfa T., and Geiger H. The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress. Blood 111 (2008) 1894-1902
    • (2008) Blood , vol.111 , pp. 1894-1902
    • Daria, D.1    Filippi, M.D.2    Knudsen, E.S.3    Faccio, R.4    Li, Z.5    Kalfa, T.6    Geiger, H.7
  • 7
    • 34249907279 scopus 로고    scopus 로고
    • shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development
    • Fasano C.A., Dimos J.T., Ivanova N.B., Lowry N., Lemischka I.R., and Temple S. shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell 1 (2007) 87-99
    • (2007) Cell Stem Cell , vol.1 , pp. 87-99
    • Fasano, C.A.1    Dimos, J.T.2    Ivanova, N.B.3    Lowry, N.4    Lemischka, I.R.5    Temple, S.6
  • 8
    • 0027185511 scopus 로고
    • Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells
    • Fleming W.H., Alpern E.J., Uchida N., Ikuta K., Spangrude G.J., and Weissman I.L. Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. J. Cell Biol. 122 (1993) 897-902
    • (1993) J. Cell Biol. , vol.122 , pp. 897-902
    • Fleming, W.H.1    Alpern, E.J.2    Uchida, N.3    Ikuta, K.4    Spangrude, G.J.5    Weissman, I.L.6
  • 11
    • 11144248047 scopus 로고    scopus 로고
    • Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages
    • Iavarone A., King E.R., Dai X.M., Leone G., Stanley E.R., and Lasorella A. Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature 432 (2004) 1040-1045
    • (2004) Nature , vol.432 , pp. 1040-1045
    • Iavarone, A.1    King, E.R.2    Dai, X.M.3    Leone, G.4    Stanley, E.R.5    Lasorella, A.6
  • 15
  • 16
    • 0031782695 scopus 로고    scopus 로고
    • Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene
    • LeCouter J.E., Kablar B., Hardy W.R., Ying C., Megeney L.A., May L.L., and Rudnicki M.A. Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. Mol. Cell. Biol. 18 (1998) 7455-7465
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7455-7465
    • LeCouter, J.E.1    Kablar, B.2    Hardy, W.R.3    Ying, C.4    Megeney, L.A.5    May, L.L.6    Rudnicki, M.A.7
  • 18
    • 33748087799 scopus 로고    scopus 로고
    • Retinoblastoma gene family expression in lymphoid tissues
    • Leoncini L., Bellan C., and De Falco G. Retinoblastoma gene family expression in lymphoid tissues. Oncogene 25 (2006) 5309-5314
    • (2006) Oncogene , vol.25 , pp. 5309-5314
    • Leoncini, L.1    Bellan, C.2    De Falco, G.3
  • 20
    • 0035318565 scopus 로고    scopus 로고
    • Molecular biology of chronic myeloid leukemia
    • Maru Y. Molecular biology of chronic myeloid leukemia. Int. J. Hematol. 73 (2001) 308-322
    • (2001) Int. J. Hematol. , vol.73 , pp. 308-322
    • Maru, Y.1
  • 21
    • 34250348814 scopus 로고    scopus 로고
    • On hematopoietic stem cell fate
    • Metcalf D. On hematopoietic stem cell fate. Immunity 26 (2007) 669-673
    • (2007) Immunity , vol.26 , pp. 669-673
    • Metcalf, D.1
  • 22
    • 30144443995 scopus 로고    scopus 로고
    • Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis
    • Mihara K., Chowdhury M., Nakaju N., Hidani S., Ihara A., Hyodo H., Yasunaga S., Takihara Y., and Kimura A. Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis. Blood 107 (2006) 305-308
    • (2006) Blood , vol.107 , pp. 305-308
    • Mihara, K.1    Chowdhury, M.2    Nakaju, N.3    Hidani, S.4    Ihara, A.5    Hyodo, H.6    Yasunaga, S.7    Takihara, Y.8    Kimura, A.9
  • 24
    • 33749350639 scopus 로고    scopus 로고
    • Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
    • Oguro H., Iwama A., Morita Y., Kamijo T., van Lohuizen M., and Nakauchi H. Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice. J. Exp. Med. 203 (2006) 2247-2253
    • (2006) J. Exp. Med. , vol.203 , pp. 2247-2253
    • Oguro, H.1    Iwama, A.2    Morita, Y.3    Kamijo, T.4    van Lohuizen, M.5    Nakauchi, H.6
  • 25
    • 38349132624 scopus 로고    scopus 로고
    • Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
    • Orford K.W., and Scadden D.T. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat. Rev. Genet. 9 (2008) 115-128
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 115-128
    • Orford, K.W.1    Scadden, D.T.2
  • 27
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • Passegue E., Wagers A.J., Giuriato S., Anderson W.C., and Weissman I.L. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J. Exp. Med. 202 (2005) 1599-1611
    • (2005) J. Exp. Med. , vol.202 , pp. 1599-1611
    • Passegue, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 28
    • 39149086121 scopus 로고    scopus 로고
    • Stems cells and the pathways to aging and cancer
    • Rossi D.J., Jamieson C.H., and Weissman I.L. Stems cells and the pathways to aging and cancer. Cell 132 (2008) 681-696
    • (2008) Cell , vol.132 , pp. 681-696
    • Rossi, D.J.1    Jamieson, C.H.2    Weissman, I.L.3
  • 29
    • 0038342441 scopus 로고    scopus 로고
    • Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
    • Sage J., Miller A.L., Perez-Mancera P.A., Wysocki J.M., and Jacks T. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424 (2003) 223-228
    • (2003) Nature , vol.424 , pp. 223-228
    • Sage, J.1    Miller, A.L.2    Perez-Mancera, P.A.3    Wysocki, J.M.4    Jacks, T.5
  • 30
    • 39449110058 scopus 로고    scopus 로고
    • Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis
    • Sankaran V.G., Orkin S.H., and Walkley C.R. Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis. Genes Dev. 22 (2008) 463-475
    • (2008) Genes Dev. , vol.22 , pp. 463-475
    • Sankaran, V.G.1    Orkin, S.H.2    Walkley, C.R.3
  • 32
    • 22844441332 scopus 로고    scopus 로고
    • The Rb tumor suppressor in stress responses and hematopoietic homeostasis
    • Spike B.T., and Macleod K.F. The Rb tumor suppressor in stress responses and hematopoietic homeostasis. Cell Cycle 4 (2005) 42-45
    • (2005) Cell Cycle , vol.4 , pp. 42-45
    • Spike, B.T.1    Macleod, K.F.2
  • 36
    • 33745161029 scopus 로고    scopus 로고
    • Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cells
    • Walkley C.R., and Orkin S.H. Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cells. Proc. Natl. Acad. Sci. USA 103 (2006) 9057-9062
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9057-9062
    • Walkley, C.R.1    Orkin, S.H.2
  • 37
    • 34250363611 scopus 로고    scopus 로고
    • Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment
    • Walkley C.R., Shea J.M., Sims N.A., Purton L.E., and Orkin S.H. Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell 129 (2007) 1081-1095
    • (2007) Cell , vol.129 , pp. 1081-1095
    • Walkley, C.R.1    Shea, J.M.2    Sims, N.A.3    Purton, L.E.4    Orkin, S.H.5
  • 38
    • 33646577125 scopus 로고    scopus 로고
    • Retinoblastoma family proteins: insights gained through genetic manipulation of mice
    • Wikenheiser-Brokamp K.A. Retinoblastoma family proteins: insights gained through genetic manipulation of mice. Cell. Mol. Life Sci. 63 (2006) 767-780
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 767-780
    • Wikenheiser-Brokamp, K.A.1
  • 39
    • 0344276481 scopus 로고    scopus 로고
    • Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential
    • Ye M., Iwasaki H., Laiosa C.V., Stadtfeld M., Xie H., Heck S., Clausen B., Akashi K., and Graf T. Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential. Immunity 19 (2003) 689-699
    • (2003) Immunity , vol.19 , pp. 689-699
    • Ye, M.1    Iwasaki, H.2    Laiosa, C.V.3    Stadtfeld, M.4    Xie, H.5    Heck, S.6    Clausen, B.7    Akashi, K.8    Graf, T.9
  • 40
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., and Morrison S.J. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 (2006) 475-482
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6    Morrison, S.J.7
  • 41
    • 31544463261 scopus 로고    scopus 로고
    • Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/Waf1 in opposite manners
    • Yu H., Yuan Y., Shen H., and Cheng T. Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/Waf1 in opposite manners. Blood 107 (2006) 1200-1206
    • (2006) Blood , vol.107 , pp. 1200-1206
    • Yu, H.1    Yuan, Y.2    Shen, H.3    Cheng, T.4
  • 42
    • 31544438803 scopus 로고    scopus 로고
    • Hematopoietic stem cells are not the direct target of spontaneous leukemic transformation in p18(INK4C)-null reconstituted mice
    • Yuan Y., Yu H., Boyer M.J., Song X., Cao S., Shen H., and Cheng T. Hematopoietic stem cells are not the direct target of spontaneous leukemic transformation in p18(INK4C)-null reconstituted mice. Cancer Res. 66 (2006) 343-351
    • (2006) Cancer Res. , vol.66 , pp. 343-351
    • Yuan, Y.1    Yu, H.2    Boyer, M.J.3    Song, X.4    Cao, S.5    Shen, H.6    Cheng, T.7
  • 44
    • 43749110075 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal
    • Zon L.I. Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature 453 (2008) 306-313
    • (2008) Nature , vol.453 , pp. 306-313
    • Zon, L.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.